HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 221272,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1032",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1030",
"results": [
{
"created": "2022-01-24T08:50:28.390565+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.686",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: UQCRC2 as Green List (high evidence)",
"entity_name": "UQCRC2",
"entity_type": "gene"
},
{
"created": "2022-01-24T08:50:28.379909+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.686",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: uqcrc2 has been classified as Green List (High Evidence).",
"entity_name": "UQCRC2",
"entity_type": "gene"
},
{
"created": "2022-01-23T13:10:32.451818+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10741",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DNHD1 were changed from Male infertility due to sperm motility disorder (MONDO:0018395) to Spermatogenic failure 65, MIM# 619712",
"entity_name": "DNHD1",
"entity_type": "gene"
},
{
"created": "2022-01-23T13:10:10.101982+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10740",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: DNHD1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Spermatogenic failure 65, MIM# 619712; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "DNHD1",
"entity_type": "gene"
},
{
"created": "2022-01-23T11:25:38.295225+11:00",
"panel_name": "Growth failure",
"panel_id": 3631,
"panel_version": "1.30",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: STT3A were changed from Congenital disorder of glycosylation, type Iw MIM#615596 to Congenital disorder of glycosylation, type Iw, AR, OMIM #615596; Congenital disorder of glycosylation, type Iw, autosomal dominant, MIM# 619714",
"entity_name": "STT3A",
"entity_type": "gene"
},
{
"created": "2022-01-23T11:25:03.651862+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4458",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: STT3A were changed from Congenital disorder of glycosylation, type Iw; OMIM #615596 to Congenital disorder of glycosylation, type Iw, AR, OMIM #615596; Congenital disorder of glycosylation, type Iw, autosomal dominant, MIM# 619714",
"entity_name": "STT3A",
"entity_type": "gene"
},
{
"created": "2022-01-23T11:24:08.542225+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10740",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: STT3A were changed from Congenital disorder of glycosylation, type Iw MIM#615596 to Congenital disorder of glycosylation, type Iw, AR, OMIM #615596; Congenital disorder of glycosylation, type Iw, autosomal dominant, MIM# 619714",
"entity_name": "STT3A",
"entity_type": "gene"
},
{
"created": "2022-01-23T11:23:36.992400+11:00",
"panel_name": "Macrocephaly_Megalencephaly",
"panel_id": 135,
"panel_version": "0.100",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: STT3A were changed from Congenital disorder of glycosylation, type Iw MIM#615596 to Congenital disorder of glycosylation, type Iw, AR, OMIM #615596; Congenital disorder of glycosylation, type Iw, autosomal dominant, MIM# 619714",
"entity_name": "STT3A",
"entity_type": "gene"
},
{
"created": "2022-01-23T11:23:05.319403+11:00",
"panel_name": "Macrocephaly_Megalencephaly",
"panel_id": 135,
"panel_version": "0.99",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: STT3A: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Congenital disorder of glycosylation, type Iw, AR, OMIM #615596, Congenital disorder of glycosylation, type Iw, autosomal dominant, MIM# 619714; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "STT3A",
"entity_type": "gene"
},
{
"created": "2022-01-23T11:22:46.615160+11:00",
"panel_name": "Congenital Disorders of Glycosylation",
"panel_id": 68,
"panel_version": "1.23",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: STT3A were changed from Congenital disorder of glycosylation, type Iw; OMIM #615596 to Congenital disorder of glycosylation, type Iw, AR, OMIM #615596; Congenital disorder of glycosylation, type Iw, autosomal dominant, MIM# 619714",
"entity_name": "STT3A",
"entity_type": "gene"
},
{
"created": "2022-01-23T11:22:07.310635+11:00",
"panel_name": "Congenital Disorders of Glycosylation",
"panel_id": 68,
"panel_version": "1.22",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: STT3A: Changed phenotypes: Congenital disorder of glycosylation, type Iw, AR, OMIM #615596, Congenital disorder of glycosylation, type Iw, autosomal dominant, MIM# 619714",
"entity_name": "STT3A",
"entity_type": "gene"
},
{
"created": "2022-01-21T17:04:45.942376+11:00",
"panel_name": "Ectodermal Dysplasia",
"panel_id": 3089,
"panel_version": "0.66",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Classified gene: CHD1 as Red List (low evidence)",
"entity_name": "CHD1",
"entity_type": "gene"
},
{
"created": "2022-01-21T17:04:45.931771+11:00",
"panel_name": "Ectodermal Dysplasia",
"panel_id": 3089,
"panel_version": "0.66",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: chd1 has been classified as Red List (Low Evidence).",
"entity_name": "CHD1",
"entity_type": "gene"
},
{
"created": "2022-01-21T17:04:39.296727+11:00",
"panel_name": "Ectodermal Dysplasia",
"panel_id": 3089,
"panel_version": "0.65",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: CHD1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "CHD1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:52:48.717298+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2665",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Deleted their review",
"entity_name": "WNT1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:50:54.871177+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2665",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "changed review comment from: LD/ID reported in ~20% according to this cohort/literature review.; to: Robinow syndrome is characterized by dysmorphic features resembling a fetal face, mesomelic limb shortening, hypoplastic external genitalia in males, and renal and vertebral anomalies.",
"entity_name": "WNT5A",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:49:41.436153+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2665",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "changed review comment from: Although WNT7A-related conditions cause ulnar abnormalities, include in this panel due to phenotypic overlap (single forearm bone may be difficult to distinguish, particularly in non-specialist setting). \nSources: Expert list; to: Limb anomalies.\r\n\r\n\r\nSources: Expert list",
"entity_name": "WNT7A",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:47:22.603414+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2665",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Deleted their review",
"entity_name": "ZIC1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:46:38.430598+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2665",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "changed review comment from: 1 family (4 affected members), Weiss et al. (2017) identified a heterozygous nonsense ZNF462 mutation.\r\n3 additional unrelated patients with a similar phenotype with heterozygous ZNF462 mutations.\r\n14 unrelated patients with WSKA, Kruszka et al. (2019) identified heterozygous loss-of-function ZNF462 mutations.; to: 1 family (4 affected members), Weiss et al. (2017) identified a heterozygous nonsense ZNF462 mutation.\r\n3 additional unrelated patients with a similar phenotype with heterozygous ZNF462 mutations.\r\n14 unrelated patients with WSKA, Kruszka et al. (2019) identified heterozygous loss-of-function ZNF462 mutations.\r\n\r\nMultiple congenital anomalies syndrome.",
"entity_name": "ZNF462",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:41:31.392128+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2665",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FOXL2 as ready",
"entity_name": "FOXL2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:41:31.378078+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2665",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: foxl2 has been classified as Red List (Low Evidence).",
"entity_name": "FOXL2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:41:27.873166+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2665",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: FOXL2 were changed from BLEPHAROPHIMOSIS, PTOSIS, AND EPICANTHUS INVERSUS SYNDROME to Blepharophimosis, epicanthus inversus, and ptosis, type 1 with premature ovarian insufficiency (POI) and type II without POI (MIM# 110100)",
"entity_name": "FOXL2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:41:14.351690+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2664",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: FOXL2 were set to ",
"entity_name": "FOXL2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:41:00.410502+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2663",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: FOXL2 was changed from MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "FOXL2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:38:18.902120+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2662",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: FOXL2 as Red List (low evidence)",
"entity_name": "FOXL2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:38:18.891912+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2662",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: foxl2 has been classified as Red List (Low Evidence).",
"entity_name": "FOXL2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:30:12.123066+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2661",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FN1 as ready",
"entity_name": "FN1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:30:12.111463+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2661",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fn1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "FN1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:29:52.466502+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2661",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: FN1 were changed from Spondylometaphyseal Dysplasia with Corner Fractures to Spondylometaphyseal dysplasia, corner fracture type (MIM#184255)",
"entity_name": "FN1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:29:39.563622+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2660",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: FN1 were set to ",
"entity_name": "FN1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:29:27.938051+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2659",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: FN1 was changed from MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "FN1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:29:13.745477+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2658",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: FN1: Rating: AMBER; Mode of pathogenicity: None; Publications: 33605604; Phenotypes: Spondylometaphyseal dysplasia, corner fracture type (MIM#184255); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "FN1",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:26:55.808626+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4457",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FMN2 as ready",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:26:55.798256+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4457",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fmn2 has been classified as Green List (High Evidence).",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:26:51.976606+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4457",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: FMN2 were changed from to Intellectual developmental disorder, autosomal recessive 47, MIM#616193",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:26:16.578853+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4456",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: FMN2 were set to ",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:22:52.371668+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4455",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: FMN2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T12:22:16.813002+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4454",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: FMN2: Rating: GREEN; Mode of pathogenicity: None; Publications: 25480035, 32162566, 24161494; Phenotypes: Intellectual developmental disorder, autosomal recessive 47, MIM#616193; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T11:02:44.754492+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10739",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FMN2 as ready",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T11:02:44.739641+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10739",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fmn2 has been classified as Green List (High Evidence).",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T11:02:34.058646+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10739",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: FMN2 were changed from to Intellectual developmental disorder, autosomal recessive 47, MIM#616193",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T11:02:13.830370+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10738",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: FMN2 were set to ",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T11:00:08.589424+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10737",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: FMN2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:59:43.774891+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: FMN2: Rating: GREEN; Mode of pathogenicity: None; Publications: 25480035, 32162566, 24161494; Phenotypes: Intellectual developmental disorder, autosomal recessive 47, MIM#616193; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:55:49.735292+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2658",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FMN2 as ready",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:55:49.723689+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2658",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fmn2 has been classified as Red List (Low Evidence).",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:55:40.822045+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2658",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: FMN2 were changed from NONSYNDROMIC AUTOSOMAL-RECESSIVE INTELLECTUAL DISABILITY to Intellectual developmental disorder, autosomal recessive 47, MIM#616193",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:55:24.503305+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2657",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: FMN2 were set to ",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:55:10.275850+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2656",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: FMN2 as Red List (low evidence)",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:55:10.263929+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2656",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fmn2 has been classified as Red List (Low Evidence).",
"entity_name": "FMN2",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:54:29.916074+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HAND1 as ready",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:54:29.905582+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hand1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:54:18.759208+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: HAND1 as Amber List (moderate evidence)",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:54:18.744892+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hand1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:53:59.035823+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10735",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HAND1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:53:37.546709+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10734",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HAND1 were set to ",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:53:19.927432+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10733",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HAND1 were changed from to Congenital heart disease, MONDO:0005453",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:52:55.974504+11:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.183",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HAND1 were changed from Congenital heart disease to Congenital heart disease, MONDO:0005453",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:52:12.227188+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2655",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HAND1 as ready",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:52:12.203100+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2655",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hand1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:52:06.561403+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2655",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HAND1 were changed from Congenital heart defects to Congenital heart disease, MONDO:0005453",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:51:33.702224+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2654",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HAND1 were set to 19586923; 28112363; 18276607; 27942761; 31286141",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:51:18.788321+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2653",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: HAND1 as Amber List (moderate evidence)",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:51:18.778095+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2653",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hand1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:50:56.832725+11:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.182",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HAND1 as ready",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:50:56.820818+11:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.182",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hand1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:50:54.409294+11:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.182",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HAND1 were changed from to Congenital heart disease",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:50:29.128653+11:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.181",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HAND1 were set to ",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:49:59.562335+11:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.180",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HAND1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:49:36.742149+11:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.179",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: HAND1 as Amber List (moderate evidence)",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:49:36.732739+11:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.179",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hand1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "HAND1",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:47:47.513122+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2652",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: FKBP8 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:47:36.745154+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2651",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: FKBP8 as Amber List (moderate evidence)",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:47:36.735936+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2651",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fkbp8 has been classified as Amber List (Moderate Evidence).",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:47:22.361054+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2650",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: FKBP8: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: Spina bifida, MONDO:0008449; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:46:36.698316+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2650",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FKBP8 as ready",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:46:36.687474+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2650",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fkbp8 has been classified as Red List (Low Evidence).",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:46:32.043662+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2650",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: FKBP8 were changed from Spina bifida, HP:0002414; Vertebral segmentation defects to Spina bifida, MONDO:0008449",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:45:59.516370+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2649",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: FKBP8 as Red List (low evidence)",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:45:59.506339+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.2649",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fkbp8 has been classified as Red List (Low Evidence).",
"entity_name": "FKBP8",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:45:04.151141+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10732",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: ILK as ready",
"entity_name": "ILK",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:45:04.139575+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10732",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ilk has been classified as Red List (Low Evidence).",
"entity_name": "ILK",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:44:44.058835+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10732",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: ILK were changed from to Dilated cardiomyopathy",
"entity_name": "ILK",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:44:24.275543+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10731",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: ILK were set to ",
"entity_name": "ILK",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:44:02.888326+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10730",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: ILK was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "ILK",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:43:44.306481+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10729",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: ILK as Red List (low evidence)",
"entity_name": "ILK",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:43:44.294493+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10729",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ilk has been classified as Red List (Low Evidence).",
"entity_name": "ILK",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:43:22.077706+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10728",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: ILK: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Dilated cardiomyopathy; Mode of inheritance: None",
"entity_name": "ILK",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:41:53.878491+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10728",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: ZIC4 as ready",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:41:53.874250+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10728",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Two individuals reported with a deletion of ZIC1 and ZIC4 and Dandy-Walker malformation.",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:41:53.833979+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10728",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: zic4 has been classified as Red List (Low Evidence).",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:41:23.553565+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10728",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: ZIC4 were set to ",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:41:04.241410+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10727",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: ZIC4 as Red List (low evidence)",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:41:04.230031+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.10727",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: zic4 has been classified as Red List (Low Evidence).",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:40:26.837610+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.393",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: ZIC4 as ready",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:40:26.833618+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.393",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Two individuals with deletions of ZIC4 and ZIC1 reported with Dandy-Walker malformation.",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:40:26.797615+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.393",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: zic4 has been classified as Red List (Low Evidence).",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:39:30.045554+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.393",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: ZIC4 were set to ",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:39:03.391729+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.392",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: ZIC4 as Red List (low evidence)",
"entity_name": "ZIC4",
"entity_type": "gene"
},
{
"created": "2022-01-21T10:39:03.376975+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.392",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: zic4 has been classified as Red List (Low Evidence).",
"entity_name": "ZIC4",
"entity_type": "gene"
}
]
}