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{
"count": 220599,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=113",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=111",
"results": [
{
"created": "2025-11-27T10:05:01.531575+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.452",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: EN2 as ready",
"entity_name": "EN2",
"entity_type": "gene"
},
{
"created": "2025-11-27T10:05:01.523618+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.452",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: en2 has been classified as Red List (Low Evidence).",
"entity_name": "EN2",
"entity_type": "gene"
},
{
"created": "2025-11-27T10:04:53.901258+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.452",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: EN2 was added\ngene: EN2 was added to Intellectual disability syndromic and non-syndromic. Sources: ClinGen\ndisputed tags were added to gene: EN2.\nMode of inheritance for gene: EN2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: EN2 were set to Complex neurodevelopmental disorder, MONDO:0100038\nReview for gene: EN2 was set to RED\nAdded comment: ClinGen DISPUTED - Feb 2021\r\n\r\nhttps://search.clinicalgenome.org/kb/gene-validity/CGGV:assertion_91eb2fc6-864c-4a4a-9b2d-0b2bdd695999-2021-02-16T170000.000Z?page=1&size=25&search= \nSources: ClinGen",
"entity_name": "EN2",
"entity_type": "gene"
},
{
"created": "2025-11-27T10:01:35.987875+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3670",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Mode of inheritance for gene: CNTN4 was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T10:01:35.058251+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3670",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Mode of inheritance for gene: CNTN4 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T10:00:38.712680+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.229",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T10:00:24.869222+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.230",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T10:00:12.148507+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.230",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T10:00:08.242656+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.451",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: KATNAL2.",
"entity_name": "KATNAL2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:59:56.638889+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.230",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:59:38.317622+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.230",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:59:33.337605+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: KIRREL3: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "KIRREL3",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:59:23.558724+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.229",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:59:10.079561+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag refuted was removed from gene: KIRREL3.\nTag disputed tag was added to gene: KIRREL3.",
"entity_name": "KIRREL3",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:59:02.167165+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.229",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:58:56.835243+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.451",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag refuted was removed from gene: KIRREL3.\nTag disputed tag was added to gene: KIRREL3.",
"entity_name": "KIRREL3",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:58:44.329496+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.229",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:58:30.532604+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.229",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:58:16.855863+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.229",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:58:02.919152+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.229",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from Intellectual disability; SCA to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:52.883466+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.228",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: CNTN4.",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:47.118016+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:46.628554+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:46.610895+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:45.993054+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:45.722075+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:44.686067+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:43.579397+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3669",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:35.331877+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3668",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:15.397156+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3667",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: CNTN4.",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:57:00.246079+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3667",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Added reviews for gene CNTN4 from panel Intellectual disability syndromic and non-syndromic",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-27T09:56:47.225815+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.228",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Added reviews for gene CNTN4 from panel Intellectual disability syndromic and non-syndromic",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-27T09:56:42.521252+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.451",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:56:25.274486+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.451",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:56:15.802179+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3666",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: CNTNAP5 as ready",
"entity_name": "CNTNAP5",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:56:15.789655+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3666",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: cntnap5 has been classified as Red List (Low Evidence).",
"entity_name": "CNTNAP5",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:56:11.648571+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.451",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:56:09.258280+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.228",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTNAP2 were changed from Cortical dysplasia-focal epilepsy syndrome, MIM# 610042 to Cortical dysplasia-focal epilepsy syndrome, MIM# 610042",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:55:55.274921+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.227",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTNAP2 were changed from Cortical dysplasia-focal epilepsy syndrome, MIM# 610042 to Cortical dysplasia-focal epilepsy syndrome, MIM# 610042",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:55:53.115732+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.451",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from complex neurodevelopmental disorder, MONDO:0100038 to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:55:40.189975+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.451",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTN4 were changed from Intellectual disability; SCA to complex neurodevelopmental disorder, MONDO:0100038",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:55:35.874283+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.226",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTNAP2 were changed from Cortical dysplasia-focal epilepsy syndrome, MIM# 610042 to Cortical dysplasia-focal epilepsy syndrome, MIM# 610042",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:55:05.578931+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.227",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTNAP2 were changed from Cortical dysplasia-focal epilepsy syndrome, MIM# 610042 to Cortical dysplasia-focal epilepsy syndrome, MIM# 610042",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:54:55.350960+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.450",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: CNTN4.",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:54:51.274282+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.227",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTNAP2 were changed from Cortical dysplasia-focal epilepsy syndrome, MIM# 610042 to Cortical dysplasia-focal epilepsy syndrome, MIM# 610042",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:54:47.523751+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.450",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: CNTN4: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: complex neurodevelopmental disorder, MONDO:0100038; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CNTN4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:54:36.285727+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.227",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTNAP2 were changed from Cortical dysplasia-focal epilepsy syndrome, MIM# 610042 to Cortical dysplasia-focal epilepsy syndrome, MIM# 610042",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:54:22.732212+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.226",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTNAP2 were changed from Cortical dysplasia-focal epilepsy syndrome, MIM# 610042 to Cortical dysplasia-focal epilepsy syndrome, MIM# 610042",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:54:04.964778+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.226",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: CNTNAP2 were changed from to Cortical dysplasia-focal epilepsy syndrome, MIM# 610042",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:53:51.323822+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.226",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Mode of inheritance for gene: CNTNAP2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CNTNAP2",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:53:00.322849+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3666",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene CNTNAP5 from panel Intellectual disability syndromic and non-syndromic",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-27T09:52:59.492587+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3666",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: CNTNAP5 was added\ngene: CNTNAP5 was added to Mendeliome. Sources: Expert Review Red,Genetic Health Queensland\ndisputed tags were added to gene: CNTNAP5.\nMode of inheritance for gene: CNTNAP5 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: CNTNAP5 were set to 20346443\nPhenotypes for gene: CNTNAP5 were set to Autism",
"entity_name": "CNTNAP5",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:52:37.186688+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.450",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: CNTNAP5.",
"entity_name": "CNTNAP5",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:52:30.599279+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.450",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: CNTNAP5: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Complex neurodevelopmental disorder, MONDO:0100038; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CNTNAP5",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:52:03.243032+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.225",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Added reviews for gene CNTNAP2 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-27T09:49:14.362546+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.450",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: TMLHE.",
"entity_name": "TMLHE",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:48:55.802475+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3665",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: TMLHE.",
"entity_name": "TMLHE",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:48:46.821260+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.450",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Source Genetic Health Queensland was removed from SLC9A9.\nSource ClinGen was added to SLC9A9.\nMode of inheritance for gene SLC9A9 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nTag disputed tag was added to SLC9A9.",
"entity_name": "SLC9A9",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:48:45.116345+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.224",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: TMLHE.",
"entity_name": "TMLHE",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:47:56.823887+11:00",
"panel_name": "Autism",
"panel_id": 51,
"panel_version": "0.224",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: SLC9A9.",
"entity_name": "SLC9A9",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:47:35.116926+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3665",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: SLC9A9.",
"entity_name": "SLC9A9",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:46:38.517843+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.449",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: SLC9A9: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "SLC9A9",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:46:30.194063+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.449",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Mode of inheritance for gene: AVPR1A was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "AVPR1A",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:46:16.655565+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.449",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Mode of inheritance for gene: AVPR1A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "AVPR1A",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:45:59.420600+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.449",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: AVPR1A were changed from to autism spectrum disorder MONDO:0005258",
"entity_name": "AVPR1A",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:45:09.262304+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3665",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: SLC6A4 were changed from Autism spectrum disorder MONDO:0005258 to Autism spectrum disorder MONDO:0005258",
"entity_name": "SLC6A4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:45:08.327004+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3665",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: SLC6A4 were changed from {Obsessive-compulsive disorder}, MIM# 164230; depression; alcohol dependence to Autism spectrum disorder MONDO:0005258",
"entity_name": "SLC6A4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:44:57.082814+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3664",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Tag disputed tag was added to gene: SLC6A4.",
"entity_name": "SLC6A4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:44:42.580594+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3664",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "commented on gene: SLC6A4: ClinGen DISPUTED - Jan 2021",
"entity_name": "SLC6A4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:44:41.990909+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3664",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: SLC6A4: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Autism spectrum disorder MONDO:0005258; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "SLC6A4",
"entity_type": "gene"
},
{
"created": "2025-11-27T09:43:56.591333+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.448",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Added reviews for gene AVPR1A from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T20:02:01.679132+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.447",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: COX4I1 as ready",
"entity_name": "COX4I1",
"entity_type": "gene"
},
{
"created": "2025-11-26T20:02:01.667953+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.447",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cox4i1 has been classified as Green List (High Evidence).",
"entity_name": "COX4I1",
"entity_type": "gene"
},
{
"created": "2025-11-26T20:01:53.276604+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.447",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COX4I1 as Green List (high evidence)",
"entity_name": "COX4I1",
"entity_type": "gene"
},
{
"created": "2025-11-26T20:01:53.268392+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.447",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cox4i1 has been classified as Green List (High Evidence).",
"entity_name": "COX4I1",
"entity_type": "gene"
},
{
"created": "2025-11-26T16:38:58.633037+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.596",
"user_name": "Lucy Spencer",
"item_type": "panel",
"text": "Added reviews for gene COX4I1 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T16:38:20.938540+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1091",
"user_name": "Lucy Spencer",
"item_type": "panel",
"text": "Added reviews for gene COX4I1 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T16:37:26.271049+11:00",
"panel_name": "Microcephaly",
"panel_id": 138,
"panel_version": "1.370",
"user_name": "Lucy Spencer",
"item_type": "panel",
"text": "Copied gene COX4I1 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T16:37:26.098942+11:00",
"panel_name": "Microcephaly",
"panel_id": 138,
"panel_version": "1.370",
"user_name": "Lucy Spencer",
"item_type": "entity",
"text": "gene: COX4I1 was added\ngene: COX4I1 was added to Microcephaly. Sources: Expert Review Amber,Expert list\nMode of inheritance for gene: COX4I1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: COX4I1 were set to 28766551; 22592081; 31290619; 40095452; 41203052\nPhenotypes for gene: COX4I1 were set to Mitochondrial complex IV deficiency, nuclear type 16, MIM#619060",
"entity_name": "COX4I1",
"entity_type": "gene"
},
{
"created": "2025-11-26T16:36:44.536442+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.446",
"user_name": "Lucy Spencer",
"item_type": "panel",
"text": "Copied gene COX4I1 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T16:36:44.160556+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.446",
"user_name": "Lucy Spencer",
"item_type": "entity",
"text": "gene: COX4I1 was added\ngene: COX4I1 was added to Intellectual disability syndromic and non-syndromic. Sources: Expert Review Amber,Expert list\nMode of inheritance for gene: COX4I1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: COX4I1 were set to 28766551; 22592081; 31290619; 40095452; 41203052\nPhenotypes for gene: COX4I1 were set to Mitochondrial complex IV deficiency, nuclear type 16, MIM#619060",
"entity_name": "COX4I1",
"entity_type": "gene"
},
{
"created": "2025-11-26T16:33:13.085312+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3664",
"user_name": "Lucy Spencer",
"item_type": "entity",
"text": "Publications for gene: COX4I1 were set to 28766551; 22592081; 31290619",
"entity_name": "COX4I1",
"entity_type": "gene"
},
{
"created": "2025-11-26T16:32:43.176264+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3663",
"user_name": "Lucy Spencer",
"item_type": "entity",
"text": "reviewed gene: COX4I1: Rating: GREEN; Mode of pathogenicity: None; Publications: 28766551, 31290619, 40095452, 41203052; Phenotypes: Mitochondrial complex IV deficiency, nuclear type 16 MIM#619060; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "COX4I1",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:47:04.377068+11:00",
"panel_name": "Ataxia - paediatric",
"panel_id": 271,
"panel_version": "1.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: COQ5 were changed from Coenzyme Q10 deficiency, primary 9, MIM#619028; Cerebellar ataxia; encephalopathy; generalized tonic-clonic seizures; intellectual disability to Coenzyme Q10 deficiency, primary, 9 MIM#619028",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:46:47.031272+11:00",
"panel_name": "Ataxia - paediatric",
"panel_id": 271,
"panel_version": "1.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: COQ5 were set to 29044765",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:46:07.938524+11:00",
"panel_name": "Ataxia - paediatric",
"panel_id": 271,
"panel_version": "1.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COQ5 as Green List (high evidence)",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:46:07.928801+11:00",
"panel_name": "Ataxia - paediatric",
"panel_id": 271,
"panel_version": "1.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:43:55.042407+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.445",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: COQ5 were changed from Coenzyme Q10 deficiency, primary 9, MIM#619028; Cerebellar ataxia; encephalopathy; generalized tonic-clonic seizures; intellectual disability to Coenzyme Q10 deficiency, primary, 9 MIM#619028",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:42:59.493917+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.444",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: COQ5 were set to 29044765",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:42:27.601875+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.443",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COQ5 as Green List (high evidence)",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:42:27.591463+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.443",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:41:28.087133+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: COQ5 as ready",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:41:28.078383+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:41:00.632736+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1090",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: COQ5 were changed from Coenzyme Q10 deficiency, primary 9, MIM#619028; Cerebellar ataxia; encephalopathy; generalized tonic-clonic seizures; intellectual disability to Coenzyme Q10 deficiency, primary, 9 MIM#619028",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:40:20.258499+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1089",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: COQ5 were set to 29044765",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:43.420737+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1088",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COQ5 as Green List (high evidence)",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:43.411650+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1088",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:36.517838+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.286",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Copied gene COQ5 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T15:39:35.847524+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: COQ5 was added\ngene: COQ5 was added to Genetic Epilepsy. Sources: Expert Review Green,Expert list,Victorian Clinical Genetics Services\nMode of inheritance for gene: COQ5 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: COQ5 were set to 29044765; 37599337; 21937992; 41199775; 36266294\nPhenotypes for gene: COQ5 were set to Coenzyme Q10 deficiency, primary 9, MIM#619028",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:24.236793+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1088",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COQ5 as Green List (high evidence)",
"entity_name": "COQ5",
"entity_type": "gene"
}
]
}