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{
"count": 220613,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=114",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=112",
"results": [
{
"created": "2025-11-26T15:46:07.928801+11:00",
"panel_name": "Ataxia - paediatric",
"panel_id": 271,
"panel_version": "1.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:43:55.042407+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.445",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: COQ5 were changed from Coenzyme Q10 deficiency, primary 9, MIM#619028; Cerebellar ataxia; encephalopathy; generalized tonic-clonic seizures; intellectual disability to Coenzyme Q10 deficiency, primary, 9 MIM#619028",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:42:59.493917+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.444",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: COQ5 were set to 29044765",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:42:27.601875+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.443",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COQ5 as Green List (high evidence)",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:42:27.591463+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.443",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:41:28.087133+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: COQ5 as ready",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:41:28.078383+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:41:00.632736+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1090",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: COQ5 were changed from Coenzyme Q10 deficiency, primary 9, MIM#619028; Cerebellar ataxia; encephalopathy; generalized tonic-clonic seizures; intellectual disability to Coenzyme Q10 deficiency, primary, 9 MIM#619028",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:40:20.258499+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1089",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: COQ5 were set to 29044765",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:43.420737+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1088",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COQ5 as Green List (high evidence)",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:43.411650+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1088",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:36.517838+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.286",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Copied gene COQ5 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T15:39:35.847524+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: COQ5 was added\ngene: COQ5 was added to Genetic Epilepsy. Sources: Expert Review Green,Expert list,Victorian Clinical Genetics Services\nMode of inheritance for gene: COQ5 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: COQ5 were set to 29044765; 37599337; 21937992; 41199775; 36266294\nPhenotypes for gene: COQ5 were set to Coenzyme Q10 deficiency, primary 9, MIM#619028",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:24.236793+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1088",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COQ5 as Green List (high evidence)",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:39:24.221780+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1088",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:37:55.815203+11:00",
"panel_name": "Ataxia - paediatric",
"panel_id": 271,
"panel_version": "1.66",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Added reviews for gene COQ5 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T15:34:46.585487+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3663",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: COQ5 as Green List (high evidence)",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T15:34:46.577934+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3663",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: coq5 has been classified as Green List (High Evidence).",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:35:30.311583+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.1087",
"user_name": "Lucy Spencer",
"item_type": "panel",
"text": "Added reviews for gene COQ5 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T14:34:32.366560+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "1.442",
"user_name": "Lucy Spencer",
"item_type": "panel",
"text": "Added reviews for gene COQ5 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T14:33:48.126996+11:00",
"panel_name": "Ataxia - paediatric",
"panel_id": 271,
"panel_version": "1.65",
"user_name": "Lucy Spencer",
"item_type": "panel",
"text": "Added reviews for gene COQ5 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-26T14:32:11.590860+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3662",
"user_name": "Lucy Spencer",
"item_type": "entity",
"text": "Phenotypes for gene: COQ5 were changed from Coenzyme Q10 deficiency, primary 9, MIM#619028; Cerebellar ataxia; encephalopathy; generalized tonic-clonic seizures; intellectual disability to Coenzyme Q10 deficiency, primary 9, MIM#619028",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:31:56.816612+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3661",
"user_name": "Lucy Spencer",
"item_type": "entity",
"text": "Publications for gene: COQ5 were set to 29044765",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:31:18.353709+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3660",
"user_name": "Lucy Spencer",
"item_type": "entity",
"text": "reviewed gene: COQ5: Rating: GREEN; Mode of pathogenicity: None; Publications: 29044765, 37599337, 21937992, 41199775, 36266294; Phenotypes: Coenzyme Q10 deficiency, primary, 9 MIM#619028; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "COQ5",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:02:44.681498+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TYROBP as ready",
"entity_name": "TYROBP",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:02:44.670832+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tyrobp has been classified as Red List (Low Evidence).",
"entity_name": "TYROBP",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:02:38.349822+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TYROBP were changed from to polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1 MONDO:0020749",
"entity_name": "TYROBP",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:02:14.686075+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TYROBP were set to ",
"entity_name": "TYROBP",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:01:15.958104+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.77",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TYROBP was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TYROBP",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:00:49.542688+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TYROBP as Red List (low evidence)",
"entity_name": "TYROBP",
"entity_type": "gene"
},
{
"created": "2025-11-26T14:00:49.535974+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tyrobp has been classified as Red List (Low Evidence).",
"entity_name": "TYROBP",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:59:15.978947+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TNFRSF11A as ready",
"entity_name": "TNFRSF11A",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:59:15.967263+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tnfrsf11a has been classified as Green List (High Evidence).",
"entity_name": "TNFRSF11A",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:59:11.129106+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TNFRSF11A were changed from to Osteopetrosis, autosomal recessive 7 MIM#612301",
"entity_name": "TNFRSF11A",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:58:42.708863+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TNFRSF11A were set to ",
"entity_name": "TNFRSF11A",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:58:20.244863+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TNFRSF11A was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TNFRSF11A",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:57:45.403233+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TGFB1 as ready",
"entity_name": "TGFB1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:57:45.391867+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tgfb1 has been classified as Green List (High Evidence).",
"entity_name": "TGFB1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:57:38.656141+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TGFB1 were changed from to Camurati-Engelmann disease MONDO:0007542",
"entity_name": "TGFB1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:57:10.879188+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.71",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TGFB1 were set to ",
"entity_name": "TGFB1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:56:38.798988+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.70",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TGFB1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TGFB1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:55:57.386366+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TCIRG1 as ready",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:55:57.379070+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tcirg1 has been classified as Green List (High Evidence).",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:55:51.858257+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TCIRG1 were changed from to Osteopetrosis, autosomal recessive 1 MIM#259700",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:55:25.422603+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TCIRG1 were set to ",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:52:43.984403+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TCIRG1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:51:58.022097+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.66",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SOST as ready",
"entity_name": "SOST",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:51:58.011687+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.66",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: sost has been classified as Green List (High Evidence).",
"entity_name": "SOST",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:51:55.870751+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.66",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SOST were changed from to sclerosteosis 1 MONDO:0010016",
"entity_name": "SOST",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:51:33.872466+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: SOST were set to ",
"entity_name": "SOST",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:51:08.090593+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: SOST was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "SOST",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:50:18.692656+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.63",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SNX10 as ready",
"entity_name": "SNX10",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:50:18.684990+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.63",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: snx10 has been classified as Green List (High Evidence).",
"entity_name": "SNX10",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:50:15.700364+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.63",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SNX10 were changed from to Osteopetrosis, autosomal recessive 8 MIM#615085",
"entity_name": "SNX10",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:49:52.899524+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.62",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: SNX10 were set to ",
"entity_name": "SNX10",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:49:31.157993+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.61",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: SNX10 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "SNX10",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:48:54.116611+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.60",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PTH1R as ready",
"entity_name": "PTH1R",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:48:54.105663+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.60",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pth1r has been classified as Green List (High Evidence).",
"entity_name": "PTH1R",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:48:50.637730+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.60",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PTH1R were changed from to Chondrodysplasia, Blomstrand type, MIM# 215045",
"entity_name": "PTH1R",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:48:27.944006+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.59",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PTH1R were set to ",
"entity_name": "PTH1R",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:48:02.161266+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.58",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PTH1R was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PTH1R",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:47:37.301548+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.57",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PTH1R: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Chondrodysplasia, Blomstrand type, MIM# 215045; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PTH1R",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:46:04.232729+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.57",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: LRP5 as ready",
"entity_name": "LRP5",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:46:04.221004+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.57",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lrp5 has been classified as Green List (High Evidence).",
"entity_name": "LRP5",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:46:01.494676+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.57",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: LRP5 were changed from autosomal dominant osteopetrosis 1 MONDO:0011877 to autosomal dominant osteopetrosis 1 MONDO:0011877",
"entity_name": "LRP5",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:45:43.618413+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.57",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: LRP5 were changed from to autosomal dominant osteopetrosis 1 MONDO:0011877",
"entity_name": "LRP5",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:44:12.245368+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.56",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: LRP5 were set to ",
"entity_name": "LRP5",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:43:48.283681+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: LRP5 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "LRP5",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:34:42.994513+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.54",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IKBKG as ready",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:34:42.985505+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.54",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ikbkg has been classified as Green List (High Evidence).",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:34:31.071380+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.54",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: IKBKG were changed from to IKBKG-related immunodeficiency with or without ectodermal dysplasia MONDO:0100162; incontinentia pigmenti MONDO:0010631",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:33:53.352359+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: IKBKG were set to ",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:33:24.828251+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.52",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: IKBKG was changed from Unknown to X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:32:56.773377+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag SV/CNV tag was added to gene: IKBKG.",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:32:24.137494+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FERMT3 as ready",
"entity_name": "FERMT3",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:32:24.129750+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fermt3 has been classified as Green List (High Evidence).",
"entity_name": "FERMT3",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:32:20.411481+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: FERMT3 were changed from to leukocyte adhesion deficiency 3 MONDO:0013016",
"entity_name": "FERMT3",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:31:40.832741+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.50",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: FERMT3 were set to ",
"entity_name": "FERMT3",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:31:13.042223+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.49",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: FERMT3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "FERMT3",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:30:40.153977+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.48",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CTSK as ready",
"entity_name": "CTSK",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:30:40.143430+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.48",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ctsk has been classified as Green List (High Evidence).",
"entity_name": "CTSK",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:30:38.207025+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.48",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CTSK were changed from to pycnodysostosis MONDO:0009940",
"entity_name": "CTSK",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:30:12.006395+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.47",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CTSK were set to ",
"entity_name": "CTSK",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:29:48.991547+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.46",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CTSK was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CTSK",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:29:11.612354+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: ANKH as ready",
"entity_name": "ANKH",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:29:11.599649+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ankh has been classified as Green List (High Evidence).",
"entity_name": "ANKH",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:29:09.209442+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: ANKH were changed from to craniometaphyseal dysplasia MONDO:0015465",
"entity_name": "ANKH",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:28:43.357175+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.44",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: ANKH were set to ",
"entity_name": "ANKH",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:28:15.950277+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.43",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: ANKH was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "ANKH",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:25:52.717152+11:00",
"panel_name": "Skeletal dysplasia",
"panel_id": 258,
"panel_version": "0.359",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: AMER1 as ready",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:25:52.709306+11:00",
"panel_name": "Skeletal dysplasia",
"panel_id": 258,
"panel_version": "0.359",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: amer1 has been classified as Green List (High Evidence).",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:25:48.885298+11:00",
"panel_name": "Skeletal dysplasia",
"panel_id": 258,
"panel_version": "0.359",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: AMER1 were changed from Osteopathia striata with cranial sclerosis\t300373; Osteopathia striata with cranial sclerosis 300373 to Osteopathia striata with cranial sclerosis, MIM# 300373",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:25:18.258871+11:00",
"panel_name": "Skeletal dysplasia",
"panel_id": 258,
"panel_version": "0.358",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: AMER1 were set to ",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:24:41.120308+11:00",
"panel_name": "Pierre Robin Sequence",
"panel_id": 160,
"panel_version": "0.57",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: AMER1 as ready",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:24:41.111545+11:00",
"panel_name": "Pierre Robin Sequence",
"panel_id": 160,
"panel_version": "0.57",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: amer1 has been classified as Green List (High Evidence).",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:24:35.472141+11:00",
"panel_name": "Pierre Robin Sequence",
"panel_id": 160,
"panel_version": "0.57",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: AMER1 were changed from to Osteopathia striata with cranial sclerosis, MIM# 300373",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:23:54.333637+11:00",
"panel_name": "Pierre Robin Sequence",
"panel_id": 160,
"panel_version": "0.56",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: AMER1 were set to ",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:23:33.307063+11:00",
"panel_name": "Pierre Robin Sequence",
"panel_id": 160,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: AMER1 was changed from Unknown to X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:22:58.316458+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: AMER1 as ready",
"entity_name": "AMER1",
"entity_type": "gene"
},
{
"created": "2025-11-26T13:22:58.305835+11:00",
"panel_name": "Osteopetrosis",
"panel_id": 150,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: amer1 has been classified as Green List (High Evidence).",
"entity_name": "AMER1",
"entity_type": "gene"
}
]
}