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{
"count": 220694,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=133",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=131",
"results": [
{
"created": "2025-11-14T12:59:46.074053+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.269",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: AP1S1 were changed from MEDNIK syndrome 609313; non-syndromic congenital intestinal failure to MEDNIK syndrome, MONDO:0012251",
"entity_name": "AP1S1",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:59:43.250981+11:00",
"panel_name": "Congenital Diarrhoea",
"panel_id": 89,
"panel_version": "1.27",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Classified gene: AP1S1 as Green List (high evidence)",
"entity_name": "AP1S1",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:59:43.242779+11:00",
"panel_name": "Congenital Diarrhoea",
"panel_id": 89,
"panel_version": "1.27",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: ap1s1 has been classified as Green List (High Evidence).",
"entity_name": "AP1S1",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:59:31.135969+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.269",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Publications for gene: AP1S1 were set to 32306098",
"entity_name": "AP1S1",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:58:53.826390+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.268",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: AP1S1 as ready",
"entity_name": "AP1S1",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:58:53.815555+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.268",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: ap1s1 has been classified as Green List (High Evidence).",
"entity_name": "AP1S1",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:58:01.088113+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.268",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene AP1S1 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T12:58:00.915526+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.268",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: AP1S1 was added\ngene: AP1S1 was added to Deafness_IsolatedAndComplex. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: AP1S1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: AP1S1 were set to 32306098\nPhenotypes for gene: AP1S1 were set to MEDNIK syndrome 609313; non-syndromic congenital intestinal failure",
"entity_name": "AP1S1",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:57:22.100620+11:00",
"panel_name": "Congenital Diarrhoea",
"panel_id": 89,
"panel_version": "1.26",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Added reviews for gene AP1S1 from panel Mendeliome",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T12:54:25.448510+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.3549",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: AP1S1: Rating: GREEN; Mode of pathogenicity: None; Publications: 19057675, 23423674, 30244301, 32306098, 24754424, 39541497; Phenotypes: MEDNIK syndrome, MONDO:0012251; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "AP1S1",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:48:59.412869+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.267",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Publications for gene: TUBB4B were set to 31884617, 38662826, 37448631, 35240325, 38719929, 39876836, 29198720",
"entity_name": "TUBB4B",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:48:45.737899+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.267",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Publications for gene: TUBB4B were set to 31884617, 38662826, 37448631, 35240325, 38719929, 39876836, 29198720",
"entity_name": "TUBB4B",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:48:03.238158+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.266",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: TUBB4B were changed from Leber congenital amaurosis with early-onset deafness, MIM#\t617879 to TUBB4B-related ciliopathy, MONDO:1060115",
"entity_name": "TUBB4B",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:47:49.428009+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.266",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Publications for gene: TUBB4B were set to 29198720",
"entity_name": "TUBB4B",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:47:16.150722+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.265",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "edited their review of gene: TUBB4B: Added comment: ClinGen definitive gene-disease association.\r\nAffected individuals also exhibited congenital or childhood onset sensorineural hearing impairment.; Changed publications: 31884617, 38662826, 37448631, 35240325, 38719929, 39876836, 29198720; Changed phenotypes: TUBB4B-related ciliopathy, MONDO:1060115",
"entity_name": "TUBB4B",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:44:43.337754+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.265",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Phenotypes for gene: TRPV4 were changed from Auditory neuropathy spectrum disorder; Peripheral neuropathy; Hearing loss to Auditory neuropathy spectrum disorder; Charcot-Marie-Tooth disease axonal type 2C, MONDO:0011633; Hearing loss",
"entity_name": "TRPV4",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:44:01.949809+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.264",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: TRPV4: Rating: GREEN; Mode of pathogenicity: None; Publications: 20037586; Phenotypes: Charcot-Marie-Tooth disease axonal type 2C, MONDO:0011633; Mode of inheritance: None",
"entity_name": "TRPV4",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:36:33.963935+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.264",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Classified gene: TMEM132E as Red List (low evidence)",
"entity_name": "TMEM132E",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:36:33.955613+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.264",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: tmem132e has been classified as Red List (Low Evidence).",
"entity_name": "TMEM132E",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:31:46.309807+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.263",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Classified gene: PSMC3 as Green List (high evidence)",
"entity_name": "PSMC3",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:31:46.299240+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.263",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: psmc3 has been classified as Green List (High Evidence).",
"entity_name": "PSMC3",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:31:27.195675+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.262",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: PSMC3: Rating: GREEN; Mode of pathogenicity: None; Publications: 37256937; Phenotypes: Neurodevelopmental disorder, MONDO:0700092, PSMC3-related; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "PSMC3",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:27:43.988347+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.262",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Classified gene: PAX2 as Green List (high evidence)",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:27:43.978588+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.262",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: pax2 has been classified as Green List (High Evidence).",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2025-11-14T12:27:22.835540+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.261",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: PAX2: Rating: GREEN; Mode of pathogenicity: None; Publications: 22213154; Phenotypes: Renal coloboma syndrome, MONDO:0007352; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:37:45.966675+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.261",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Classified gene: DSPP as Green List (high evidence)",
"entity_name": "DSPP",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:37:45.956427+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.261",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: dspp has been classified as Green List (High Evidence).",
"entity_name": "DSPP",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:37:14.560377+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "reviewed gene: DSPP: Rating: GREEN; Mode of pathogenicity: None; Publications: 11175790, 15690376, 17686168, 15592686, 18456718, 15241678; Phenotypes: Dentinogenesis imperfecta, MONDO:0018849; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "DSPP",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:55.134381+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: ADAMTS1 as ready",
"entity_name": "ADAMTS1",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:55.098604+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: adamts1 has been classified as Red List (Low Evidence).",
"entity_name": "ADAMTS1",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:39.699608+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: ANKRD24 as ready",
"entity_name": "ANKRD24",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:39.684777+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: ankrd24 has been classified as Red List (Low Evidence).",
"entity_name": "ANKRD24",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:32.539533+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: ATP11A as ready",
"entity_name": "ATP11A",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:32.532219+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: atp11a has been classified as Green List (High Evidence).",
"entity_name": "ATP11A",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:20.491346+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: CPD as ready",
"entity_name": "CPD",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:20.484184+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: cpd has been classified as Green List (High Evidence).",
"entity_name": "CPD",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:09.775047+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: GOSR2 as ready",
"entity_name": "GOSR2",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:23:09.767464+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: gosr2 has been classified as Red List (Low Evidence).",
"entity_name": "GOSR2",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:22:59.623297+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: IKZF2 as ready",
"entity_name": "IKZF2",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:22:59.612428+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: ikzf2 has been classified as Green List (High Evidence).",
"entity_name": "IKZF2",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:22:50.826901+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: MEPE as ready",
"entity_name": "MEPE",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:22:50.819486+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: mepe has been classified as Amber List (Moderate Evidence).",
"entity_name": "MEPE",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:22:41.677756+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: MPDZ as ready",
"entity_name": "MPDZ",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:22:41.667332+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: mpdz has been classified as Red List (Low Evidence).",
"entity_name": "MPDZ",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:22:32.492128+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: NCOA3 as ready",
"entity_name": "NCOA3",
"entity_type": "gene"
},
{
"created": "2025-11-14T11:22:32.483952+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: ncoa3 has been classified as Red List (Low Evidence).",
"entity_name": "NCOA3",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:30:36.048628+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: REST as ready",
"entity_name": "REST",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:30:36.037905+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: rest has been classified as Amber List (Moderate Evidence).",
"entity_name": "REST",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:30:27.590123+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: SEZ6 as ready",
"entity_name": "SEZ6",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:30:27.581787+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: sez6 has been classified as Red List (Low Evidence).",
"entity_name": "SEZ6",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:30:17.832051+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: SMARCA4 as ready",
"entity_name": "SMARCA4",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:30:17.824523+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: smarca4 has been classified as Red List (Low Evidence).",
"entity_name": "SMARCA4",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:30:04.565978+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: TECTB as ready",
"entity_name": "TECTB",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:30:04.554849+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: tectb has been classified as Red List (Low Evidence).",
"entity_name": "TECTB",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:53.868174+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: TRRAP as ready",
"entity_name": "TRRAP",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:53.858357+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: trrap has been classified as Red List (Low Evidence).",
"entity_name": "TRRAP",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:44.355146+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: CENPP as ready",
"entity_name": "CENPP",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:44.347520+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: cenpp has been classified as Red List (Low Evidence).",
"entity_name": "CENPP",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:35.618564+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: MAP3K1 as ready",
"entity_name": "MAP3K1",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:35.608673+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: map3k1 has been classified as Red List (Low Evidence).",
"entity_name": "MAP3K1",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:25.773420+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: TOGARAM2 as ready",
"entity_name": "TOGARAM2",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:25.763690+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: togaram2 has been classified as Red List (Low Evidence).",
"entity_name": "TOGARAM2",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:16.848631+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: STX4 as ready",
"entity_name": "STX4",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:16.841091+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: stx4 has been classified as Amber List (Moderate Evidence).",
"entity_name": "STX4",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:05.411617+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: MVD as ready",
"entity_name": "MVD",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:29:05.403803+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: mvd has been classified as Red List (Low Evidence).",
"entity_name": "MVD",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:28:57.261745+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: PKHD1L1 as ready",
"entity_name": "PKHD1L1",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:28:57.250389+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: pkhd1l1 has been classified as Green List (High Evidence).",
"entity_name": "PKHD1L1",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:28:43.492908+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: FXN as ready",
"entity_name": "FXN",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:28:43.482799+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: fxn has been classified as Green List (High Evidence).",
"entity_name": "FXN",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:28:33.504486+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: MPZ as ready",
"entity_name": "MPZ",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:28:33.496685+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: mpz has been classified as Red List (Low Evidence).",
"entity_name": "MPZ",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:28:23.659047+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: PCDH9 as ready",
"entity_name": "PCDH9",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:28:23.649131+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: pcdh9 has been classified as Red List (Low Evidence).",
"entity_name": "PCDH9",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:27:48.654355+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: TMEM126A as ready",
"entity_name": "TMEM126A",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:27:48.646485+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: tmem126a has been classified as Amber List (Moderate Evidence).",
"entity_name": "TMEM126A",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:27:20.748723+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Marked gene: NEFL as ready",
"entity_name": "NEFL",
"entity_type": "gene"
},
{
"created": "2025-11-14T10:27:20.738125+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: nefl has been classified as Green List (High Evidence).",
"entity_name": "NEFL",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:50:53.190840+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.260",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "HPO terms changed from Hearing impairment, HP:0000365 to Hearing impairment, HP:0000365; Sensorineural hearing impairment HP:0000407",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:30:29.460563+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.259",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene NEFL from panel Auditory Neuropathy",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:30:29.161836+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.259",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: NEFL was added\ngene: NEFL was added to Deafness_IsolatedAndComplex. Sources: Expert Review Green,Literature\nMode of inheritance for gene: NEFL was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: NEFL were set to 21176974\nPhenotypes for gene: NEFL were set to Syndromic auditory neuropathy spectrum disorder",
"entity_name": "NEFL",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:28:50.092523+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.258",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene TMEM126A from panel Auditory Neuropathy",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:28:49.910611+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.258",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: TMEM126A was added\ngene: TMEM126A was added to Deafness_IsolatedAndComplex. Sources: Expert Review Amber,Literature\nMode of inheritance for gene: TMEM126A was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: TMEM126A were set to 21176974\nPhenotypes for gene: TMEM126A were set to Optic atrophy 7 MIM#612989; Syndromic auditory neuropathy spectrum disorder",
"entity_name": "TMEM126A",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:27:36.335843+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.257",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Classified gene: PMP22 as Green List (high evidence)",
"entity_name": "PMP22",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:27:36.325235+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.257",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: pmp22 has been classified as Green List (High Evidence).",
"entity_name": "PMP22",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:27:19.249838+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.257",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Classified gene: PMP22 as Green List (high evidence)",
"entity_name": "PMP22",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:27:19.227684+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.257",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "Gene: pmp22 has been classified as Green List (High Evidence).",
"entity_name": "PMP22",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:26:48.372708+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.256",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene PCDH9 from panel Auditory Neuropathy",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:26:48.147869+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.256",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: PCDH9 was added\ngene: PCDH9 was added to Deafness_IsolatedAndComplex. Sources: Expert Review Red,Literature\nMode of inheritance for gene: PCDH9 was set to Unknown\nPublications for gene: PCDH9 were set to 21176974\nPhenotypes for gene: PCDH9 were set to Non-syndromic auditory neuropathy spectrum disorder",
"entity_name": "PCDH9",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:26:08.907437+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.255",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene MPZ from panel Auditory Neuropathy",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:26:08.691786+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.255",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: MPZ was added\ngene: MPZ was added to Deafness_IsolatedAndComplex. Sources: Expert Review Red,Literature\nMode of inheritance for gene: MPZ was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: MPZ were set to 21176974; 12845552; 12805115\nPhenotypes for gene: MPZ were set to Syndromic auditory neuropathy spectrum disorder",
"entity_name": "MPZ",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:25:32.534518+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.255",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene FXN from panel Auditory Neuropathy",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:25:32.364310+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.255",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: FXN was added\ngene: FXN was added to Deafness_IsolatedAndComplex. Sources: Expert Review Green,Literature\nSTR tags were added to gene: FXN.\nMode of inheritance for gene: FXN was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: FXN were set to 18515321; 25791504\nPhenotypes for gene: FXN were set to Friedreich ataxia MIM#229300",
"entity_name": "FXN",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:23:38.066593+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.254",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene PKHD1L1 from panel Deafness_Isolated",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:23:37.896894+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.254",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: PKHD1L1 was added\ngene: PKHD1L1 was added to Deafness_IsolatedAndComplex. Sources: Expert Review Green,Literature\nMode of inheritance for gene: PKHD1L1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: PKHD1L1 were set to 38459354\nPhenotypes for gene: PKHD1L1 were set to non syndromic hearing loss (MONDO:0020678)",
"entity_name": "PKHD1L1",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:21:25.772314+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.253",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene MVD from panel Deafness_Isolated",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:21:25.586927+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.253",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: MVD was added\ngene: MVD was added to Deafness_IsolatedAndComplex. Sources: Expert Review Red,Literature\nMode of inheritance for gene: MVD was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: MVD were set to 34135477\nPhenotypes for gene: MVD were set to Nonsyndromic genetic hearing loss MONDO:0019497, MPDZ-related",
"entity_name": "MVD",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:20:49.772359+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.252",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene STX4 from panel Deafness_Isolated",
"entity_name": null,
"entity_type": null
},
{
"created": "2025-11-14T09:20:49.510187+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.252",
"user_name": "Chirag Patel",
"item_type": "entity",
"text": "gene: STX4 was added\ngene: STX4 was added to Deafness_IsolatedAndComplex. Sources: Expert Review Amber,Literature\nMode of inheritance for gene: STX4 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: STX4 were set to 36355422\nPhenotypes for gene: STX4 were set to Deafness, autosomal recessive 123, MIM# 620745",
"entity_name": "STX4",
"entity_type": "gene"
},
{
"created": "2025-11-14T09:20:11.946663+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.252",
"user_name": "Chirag Patel",
"item_type": "panel",
"text": "Copied gene TOGARAM2 from panel Deafness_Isolated",
"entity_name": null,
"entity_type": null
}
]
}