HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 220212,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1394",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1392",
"results": [
{
"created": "2021-03-06T13:29:52.835088+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.190",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS24 were changed from to Diamond-blackfan anemia 3, MIM# 610629; MONDO:0012529",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:29:25.009056+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.189",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPS24 were set to ",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:28:57.157161+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.188",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPS24 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:28:28.501863+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.187",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPS24: Rating: GREEN; Mode of pathogenicity: None; Publications: 17186470, 23812780, 25946618; Phenotypes: Diamond-blackfan anemia 3, MIM# 610629, MONDO:0012529; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:27:57.122901+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6597",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPS24 as ready",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:27:57.112262+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6597",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rps24 has been classified as Green List (High Evidence).",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:27:50.052638+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6597",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS24 were changed from to Diamond-blackfan anemia 3, MIM# 610629; MONDO:0012529",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:27:31.424800+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6596",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPS24 were set to ",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:27:12.087910+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6595",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPS24 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:26:48.896301+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6594",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPS24: Rating: GREEN; Mode of pathogenicity: None; Publications: 17186470, 23812780, 25946618; Phenotypes: Diamond-blackfan anemia 3, MIM# 610629, MONDO:0012529; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:25:16.116587+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPS24 as ready",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:25:16.108243+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rps24 has been classified as Green List (High Evidence).",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:25:12.806933+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS24 were changed from to Diamond-blackfan anemia 3, MIM# 610629; MONDO:0012529",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:24:20.128329+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPS24 were set to ",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:23:52.495853+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPS24 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:23:23.729871+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.66",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPS24: Rating: GREEN; Mode of pathogenicity: None; Publications: 17186470, 23812780, 25946618; Phenotypes: Diamond-blackfan anemia 3, MIM# 610629; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS24",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:20:36.543430+11:00",
"panel_name": "Radial Ray Abnormalities",
"panel_id": 163,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPS19 as ready",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:20:36.532074+11:00",
"panel_name": "Radial Ray Abnormalities",
"panel_id": 163,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rps19 has been classified as Green List (High Evidence).",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:20:31.369157+11:00",
"panel_name": "Radial Ray Abnormalities",
"panel_id": 163,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS19 were changed from to Diamond-Blackfan anemia 1, MIM# 105650; MONDO:0007110",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:20:04.415315+11:00",
"panel_name": "Radial Ray Abnormalities",
"panel_id": 163,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPS19 were set to ",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:19:34.072285+11:00",
"panel_name": "Radial Ray Abnormalities",
"panel_id": 163,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPS19 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:19:05.132047+11:00",
"panel_name": "Radial Ray Abnormalities",
"panel_id": 163,
"panel_version": "0.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPS19: Rating: GREEN; Mode of pathogenicity: None; Publications: 9988267, 10590074; Phenotypes: Diamond-Blackfan anemia 1, MIM# 105650, MONDO:0007110; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:17:36.601429+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6594",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS19 were changed from Diamond-Blackfan anemia 1, MIM# 105650 to Diamond-Blackfan anemia 1, MIM# 105650; MONDO:0007110",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:17:09.207712+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.187",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPS19 as ready",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:17:09.196252+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.187",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rps19 has been classified as Green List (High Evidence).",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:17:06.781847+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.187",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS19 were changed from to Diamond-Blackfan anemia 1, MIM# 105650; MONDO:0007110",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:16:30.368749+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.186",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPS19 were set to ",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:15:53.266328+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.66",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS19 were changed from Diamond-Blackfan anemia 1, MIM# 105650 to Diamond-Blackfan anemia 1, MIM# 105650; MONDO:0007110",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T13:15:23.748539+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: RPS19: Changed phenotypes: Diamond-Blackfan anemia 1, MIM# 105650, MONDO:0007110",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T12:11:13.817342+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.185",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPS19 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T12:09:16.629388+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.184",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPS19: Rating: GREEN; Mode of pathogenicity: None; Publications: 9988267, 10590074; Phenotypes: Diamond-Blackfan anemia 1, MIM# 105650; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T12:07:30.903599+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6593",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPS19 as ready",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T12:07:30.884032+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6593",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rps19 has been classified as Green List (High Evidence).",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T12:07:14.016634+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6593",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS19 were changed from to Diamond-Blackfan anemia 1, MIM# 105650",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T12:06:55.513809+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6592",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPS19 were set to ",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T12:06:33.168505+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6591",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPS19 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T12:06:13.096524+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6590",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPS19: Rating: GREEN; Mode of pathogenicity: None; Publications: 9988267, 10590074; Phenotypes: Diamond-Blackfan anemia 1, MIM# 105650; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:30:45.086300+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPS19 as ready",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:30:45.075479+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rps19 has been classified as Green List (High Evidence).",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:30:42.258079+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS19 were changed from to Diamond-Blackfan anemia 1, MIM# 105650",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:30:14.738701+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPS19 were set to ",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:29:48.749721+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.63",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPS19 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:29:19.561558+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.62",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPS19: Rating: GREEN; Mode of pathogenicity: None; Publications: 9988267, 10590074; Phenotypes: Diamond-Blackfan anemia 1, MIM# 105650; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS19",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:26:41.459360+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.62",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPS10 as ready",
"entity_name": "RPS10",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:26:41.449157+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.62",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rps10 has been classified as Green List (High Evidence).",
"entity_name": "RPS10",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:26:38.468068+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.62",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPS10 were changed from to Diamond-Blackfan anemia 9, MIM# 613308",
"entity_name": "RPS10",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:26:09.690361+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.61",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPS10 were set to ",
"entity_name": "RPS10",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:25:42.448093+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.60",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPS10 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS10",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:25:13.688444+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.59",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPS10: Rating: GREEN; Mode of pathogenicity: None; Publications: 20116044, 23718193, 25946618; Phenotypes: Diamond-Blackfan anemia 9, MIM# 613308; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPS10",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:18:30.428501+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6590",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: ACKR3 were changed from Oculomotor synkinesis; Ptosis to Oculomotor-abducens synkinesis, MIM# 619215",
"entity_name": "ACKR3",
"entity_type": "gene"
},
{
"created": "2021-03-06T09:18:03.037043+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6589",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: ACKR3: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: Oculomotor-abducens synkinesis, MIM# 619215; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "ACKR3",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:48:01.836090+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6589",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "gene: SIAH1 was added\ngene: SIAH1 was added to Mendeliome. Sources: Literature\nMode of inheritance for gene: SIAH1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown\nPublications for gene: SIAH1 were set to 32430360\nPhenotypes for gene: SIAH1 were set to Developmental delay; Infantile hypotonia; Dysmorphic features; Laryngomalacia\nReview for gene: SIAH1 was set to GREEN\nAdded comment: - PMID: 32430360 (2021) - Five unrelated individuals with shared features of developmental delay, infantile hypotonia, dysmorphic features and laryngomalacia. All had speech delay and where cognitive assessment was age appropriate individuals exhibited learning difficulties. Trio WES revealed distinct de novo variants in SIAH1. In vitro assays demonstrated that SIAH1 mutants induce loss of Wnt stimulatory activity. \nSources: Literature",
"entity_name": "SIAH1",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:27:10.992386+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6589",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SYCP2L as ready",
"entity_name": "SYCP2L",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:27:10.984845+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6589",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: sycp2l has been classified as Amber List (Moderate Evidence).",
"entity_name": "SYCP2L",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:26:57.467356+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6589",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: SYCP2L as Amber List (moderate evidence)",
"entity_name": "SYCP2L",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:26:57.456876+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6589",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: sycp2l has been classified as Amber List (Moderate Evidence).",
"entity_name": "SYCP2L",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:24:33.017841+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6588",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPL5 as ready",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:24:33.009646+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6588",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rpl5 has been classified as Green List (High Evidence).",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:24:08.602249+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6588",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPL5 were changed from to Diamond-Blackfan anemia 6, MIM# 612561; MONDO:0012937",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:23:49.428634+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6587",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPL5 were set to ",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:23:31.011942+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6586",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPL5 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:23:10.395094+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6585",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPL5: Rating: GREEN; Mode of pathogenicity: None; Publications: 19061985; Phenotypes: Diamond-Blackfan anemia 6, MIM# 612561, MONDO:0012937; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:22:13.107301+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.56",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: RPL5: Changed phenotypes: Diamond-Blackfan anemia 6, MIM# 612561, MONDO:0012937",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:21:56.088433+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.56",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPL5 as ready",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:21:56.076613+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.56",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rpl5 has been classified as Green List (High Evidence).",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:21:51.946109+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.56",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPL5 were set to ",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:21:21.307040+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPL5 were changed from to Diamond-Blackfan anemia 6, MIM# 612561; MONDO:0012937",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:20:44.217684+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.54",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPL5 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:20:03.354583+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPL5: Rating: GREEN; Mode of pathogenicity: None; Publications: 19061985; Phenotypes: Diamond-Blackfan anemia 6, MIM# 612561; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL5",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:18:55.052730+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.184",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPL35A as ready",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:18:55.032040+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.184",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rpl35a has been classified as Green List (High Evidence).",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:18:52.077390+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.184",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPL35A were changed from to Diamond-Blackfan anemia 5, MIM# 612528",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:18:19.792994+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.183",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPL35A were set to ",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:17:51.843037+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.182",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPL35A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:17:14.431636+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.181",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPL35A: Rating: GREEN; Mode of pathogenicity: None; Publications: 18535205, 32241839; Phenotypes: Diamond-Blackfan anemia 5, MIM# 612528; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:16:30.190014+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6585",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag SV/CNV tag was added to gene: RPL35A.",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:16:02.622348+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6585",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPL35A as ready",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:16:02.612227+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6585",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rpl35a has been classified as Green List (High Evidence).",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:15:53.678828+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6585",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPL35A were changed from to Diamond-Blackfan anemia 5, MIM# 612528",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:15:30.482531+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6584",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPL35A were set to ",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:13:27.408650+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6583",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPL35A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:13:13.597337+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6582",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "gene: SYCP2L was added\ngene: SYCP2L was added to Mendeliome. Sources: Literature\nMode of inheritance for gene: SYCP2L was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: SYCP2L were set to 32303603\nPhenotypes for gene: SYCP2L were set to Premature ovarian insufficiency\nReview for gene: SYCP2L was set to AMBER\nAdded comment: - PMID: 32303603 (2021) - Two unrelated individuals with premature ovarian insufficiency and homozygous variants (c.150_151del (p.Ser52Profs*7), c.999A>G (p.Ile333Met)) in SYCP2L.\r\nIn vitro assays revealed that mutant SYCP2L proteins induced mislocalisation and reduced expression. Sycp2l knockout mice exhibit accelerated reproductive ageing. \nSources: Literature",
"entity_name": "SYCP2L",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:13:11.910621+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "changed review comment from: Over 50 unrelated individuals reported.; to: Over 50 unrelated individuals reported. Large deletions common.",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:12:57.339704+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6582",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPL35A: Rating: GREEN; Mode of pathogenicity: None; Publications: 18535205, 32241839; Phenotypes: Diamond-Blackfan anemia 5, MIM# 612528; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:12:02.960043+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPL35A as ready",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:12:02.949271+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rpl35a has been classified as Green List (High Evidence).",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:11:55.044035+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag SV/CNV tag was added to gene: RPL35A.",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:11:30.826880+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPL35A were changed from to Diamond-Blackfan anemia 5, MIM# 612528",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:10:43.046036+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.52",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPL35A were set to ",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:10:19.143042+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPL35A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:09:49.069333+11:00",
"panel_name": "Diamond Blackfan anaemia",
"panel_id": 98,
"panel_version": "0.50",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPL35A: Rating: GREEN; Mode of pathogenicity: None; Publications: 18535205, 32241839; Phenotypes: Diamond-Blackfan anemia 5, MIM# 612528; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL35A",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:08:01.088331+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6582",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPL27 as ready",
"entity_name": "RPL27",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:08:01.079629+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6582",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rpl27 has been classified as Red List (Low Evidence).",
"entity_name": "RPL27",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:07:53.044073+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6582",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RPL27 were changed from to Diamond-Blackfan anemia 16, MIM# 617408",
"entity_name": "RPL27",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:07:32.197005+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6581",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RPL27 were set to ",
"entity_name": "RPL27",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:07:12.540382+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6580",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RPL27 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL27",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:06:48.567543+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6579",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: RPL27 as Red List (low evidence)",
"entity_name": "RPL27",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:06:48.554506+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6579",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rpl27 has been classified as Red List (Low Evidence).",
"entity_name": "RPL27",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:06:23.085375+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.6578",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RPL27: Rating: RED; Mode of pathogenicity: None; Publications: 25424902; Phenotypes: Diamond-Blackfan anemia 16, MIM# 617408; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RPL27",
"entity_type": "gene"
},
{
"created": "2021-03-05T21:05:44.229181+11:00",
"panel_name": "Bone Marrow Failure",
"panel_id": 56,
"panel_version": "0.181",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RPL27 as ready",
"entity_name": "RPL27",
"entity_type": "gene"
}
]
}