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{
"count": 220212,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1405",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1403",
"results": [
{
"created": "2021-02-18T18:53:38.285766+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rasa1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "RASA1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:53:23.002989+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: RASA1 as Amber List (moderate evidence)",
"entity_name": "RASA1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:53:22.995646+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rasa1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "RASA1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:53:14.357403+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RASA1: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: Capillary malformation-arteriovenous malformation syndrome; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "RASA1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:52:42.540890+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: PTEN.",
"entity_name": "PTEN",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:52:26.814438+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PTEN as ready",
"entity_name": "PTEN",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:52:26.806924+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pten has been classified as Green List (High Evidence).",
"entity_name": "PTEN",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:52:17.149309+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PTEN: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Epidermal naevi, Cowden syndrome, Bannayan-Riley-Ruvalcaba syndrome, Melanoma; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PTEN",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:51:42.759657+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PIK3CA as ready",
"entity_name": "PIK3CA",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:51:42.751473+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pik3ca has been classified as Green List (High Evidence).",
"entity_name": "PIK3CA",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:51:39.422078+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PIK3CA were changed from Vascular malformations; PIK3CA-related overgrowth syndromes to Vascular malformations; PIK3CA-related overgrowth syndromes; CLAPO syndrome, somatic 613089; CLOVE syndrome, somatic 612918; Nevus, epidermal, somatic 162900",
"entity_name": "PIK3CA",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:51:27.984686+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: PIK3CA.",
"entity_name": "PIK3CA",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:51:19.574924+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PIK3CA: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Vascular malformations, PIK3CA-related overgrowth syndromes, CLAPO syndrome, somatic 613089, CLOVE syndrome, somatic 612918, Nevus, epidermal, somatic 162900; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PIK3CA",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:49:58.554668+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: NRAS.",
"entity_name": "NRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:49:52.003174+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NRAS as ready",
"entity_name": "NRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:49:51.995086+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nras has been classified as Green List (High Evidence).",
"entity_name": "NRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:49:37.626192+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: NRAS: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Melanocytic naevi, Congenital melanocytic naevus syndrome; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:49:11.181643+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NF2 as ready",
"entity_name": "NF2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:49:11.166687+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nf2 has been classified as Green List (High Evidence).",
"entity_name": "NF2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:49:05.316871+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NF2 were changed from NF2; NEUROFIBROMATOSIS, TYPE II to Schwannomatosis, somatic 162091; Meningioma, NF2-related, somatic 607174; Neurofibromatosis, type 2 101000",
"entity_name": "NF2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:48:45.200318+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.8",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NF2 was changed from MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NF2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:48:35.497582+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: NF2: Changed publications: 29409008",
"entity_name": "NF2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:48:21.155972+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: NF2: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Schwannomatosis, somatic 162091, Meningioma, NF2-related, somatic 607174, Neurofibromatosis, type 2 101000; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NF2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:46:52.534877+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NF1 as ready",
"entity_name": "NF1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:46:52.527162+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nf1 has been classified as Green List (High Evidence).",
"entity_name": "NF1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:46:50.412831+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NF1 were changed from Neurofibromatosis type I to Neurofibromatosis type I, MIM#162200",
"entity_name": "NF1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:46:40.260972+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: NF1: Changed phenotypes: Neurofibromatosis type I, MIM#162200",
"entity_name": "NF1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:45:50.215124+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: NF1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Neurofibromatosis type I; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NF1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:45:00.650303+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MTOR as ready",
"entity_name": "MTOR",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:45:00.637953+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mtor has been classified as Green List (High Evidence).",
"entity_name": "MTOR",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:44:52.783195+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MTOR: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Hypomelanosis of Ito/Blaschko-linear hypopigmentation; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MTOR",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:44:15.451000+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MAP3K3 as ready",
"entity_name": "MAP3K3",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:44:15.439831+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: map3k3 has been classified as Green List (High Evidence).",
"entity_name": "MAP3K3",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:44:04.021566+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MAP3K3: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Verrucous haemangiomas; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MAP3K3",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:43:37.297334+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: GNAS.",
"entity_name": "GNAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:43:03.469782+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Panel types changed to Rare Disease",
"entity_name": null,
"entity_type": null
},
{
"created": "2021-02-18T18:41:33.724422+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: MAP2K1 as Amber List (moderate evidence)",
"entity_name": "MAP2K1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:41:33.714660+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: map2k1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "MAP2K1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:41:11.785837+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MAP2K1: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: vascular malformations; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MAP2K1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:39:58.535424+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KRT10 as ready",
"entity_name": "KRT10",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:39:58.524742+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: krt10 has been classified as Green List (High Evidence).",
"entity_name": "KRT10",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:39:49.940860+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: KRT10: Changed phenotypes: Epidermolytic hyperkeratosis MIM#113800, Pachyonychia congenita, Ichythosis with confetti, MIM#609165, Palmoplantar keratoderma",
"entity_name": "KRT10",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:38:52.632125+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: KRT10: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Epidermolytic hyperkeratosis, Pachyonychia congenita, Ichythosis with confetti, Palmoplantar keratoderma; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "KRT10",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:38:30.288274+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KRT1 as ready",
"entity_name": "KRT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:38:30.269330+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: krt1 has been classified as Green List (High Evidence).",
"entity_name": "KRT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:38:26.119236+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: KRT1.",
"entity_name": "KRT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:38:15.569498+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: KRT1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Ichthyosis histrix, Epidermolytic hyperkeratosis, Palmoplantar keratoderma; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "KRT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:37:54.481276+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KRAS as ready",
"entity_name": "KRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:37:54.470313+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kras has been classified as Green List (High Evidence).",
"entity_name": "KRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:37:49.698357+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: KRAS.",
"entity_name": "KRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:37:38.651635+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: KRAS: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Epidermal naevi, Schimmelpenning syndrome; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "KRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:37:05.327363+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IDH2 as ready",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:37:05.319109+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: idh2 has been classified as Green List (High Evidence).",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:37:00.461254+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: IDH2.",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:36:53.217076+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: IDH2: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Maffucci syndrome, Ollier disease; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:36:32.582137+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IDH1 as ready",
"entity_name": "IDH1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:36:32.568683+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: idh1 has been classified as Green List (High Evidence).",
"entity_name": "IDH1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:36:27.424120+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: IDH1.",
"entity_name": "IDH1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:36:19.249460+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: IDH1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Maffucci syndrome, Ollier disease; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "IDH1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:35:51.882400+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HRAS as ready",
"entity_name": "HRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:35:51.872238+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hras has been classified as Green List (High Evidence).",
"entity_name": "HRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:35:47.618205+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: HRAS.",
"entity_name": "HRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:35:38.639115+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: HRAS: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Phakomatosis pigmentokeratotica, Epidermal naevi, Woolly hair, Costello syndrome, Schimmelpenning syndrome; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "HRAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:35:02.960830+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GNAS as ready",
"entity_name": "GNAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:35:02.950595+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gnas has been classified as Green List (High Evidence).",
"entity_name": "GNAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:34:59.679906+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: GNAS were set to 12970318",
"entity_name": "GNAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:34:34.938840+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: GNAS: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: McCune-Albright syndrome; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GNAS",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:34:09.957231+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GNAQ as ready",
"entity_name": "GNAQ",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:34:09.947651+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gnaq has been classified as Green List (High Evidence).",
"entity_name": "GNAQ",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:34:01.566339+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: GNAQ: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Extensive dermal melanocytosis, Sturge Weber syndrome, Phakomatosis pigmentovascularis; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GNAQ",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:33:36.178710+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GNA14 as ready",
"entity_name": "GNA14",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:33:36.159022+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gna14 has been classified as Green List (High Evidence).",
"entity_name": "GNA14",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:33:32.276446+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: GNA14.",
"entity_name": "GNA14",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:33:20.840041+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: GNA14: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Kaposiform endothelioma, Tufted angioma; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GNA14",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:32:43.394122+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GNA11 as ready",
"entity_name": "GNA11",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:32:43.380937+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gna11 has been classified as Green List (High Evidence).",
"entity_name": "GNA11",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:32:38.837762+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: GNA11.",
"entity_name": "GNA11",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:32:29.443817+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: GNA11: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Extensive dermal melanocytosis, Phakomatosis pigmentovascularis; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GNA11",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:32:04.982780+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: ACTB.",
"entity_name": "ACTB",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:31:43.935452+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: AKT1.",
"entity_name": "AKT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:31:35.527086+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: FGFR1.",
"entity_name": "FGFR1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:31:25.506433+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FGFR3 as ready",
"entity_name": "FGFR3",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:31:25.498993+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fgfr3 has been classified as Green List (High Evidence).",
"entity_name": "FGFR3",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:31:18.863628+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: FGFR3.",
"entity_name": "FGFR3",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:31:10.555432+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: FGFR3: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Epidermal naevi, Syringocystadenoma papilliferum; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "FGFR3",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:30:36.434680+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: FGFR1 as ready",
"entity_name": "FGFR1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:30:36.420823+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: fgfr1 has been classified as Green List (High Evidence).",
"entity_name": "FGFR1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:30:29.121851+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: FGFR1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Epidermal naevi; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "FGFR1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:29:54.587198+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: AKT1 as ready",
"entity_name": "AKT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:29:54.572336+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: akt1 has been classified as Green List (High Evidence).",
"entity_name": "AKT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:29:52.430672+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: AKT1 were changed from Proteus syndrome to Proteus syndrome, somatic\t176920",
"entity_name": "AKT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:29:39.387529+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: AKT1: Rating: GREEN; Mode of pathogenicity: None; Publications: 33030203; Phenotypes: Proteus syndrome, somatic 176920; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "AKT1",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:28:53.350166+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: ACTB as ready",
"entity_name": "ACTB",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:28:53.341535+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: actb has been classified as Green List (High Evidence).",
"entity_name": "ACTB",
"entity_type": "gene"
},
{
"created": "2021-02-18T18:28:51.660910+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: ACTB were changed from to Becker's naevus",
"entity_name": "ACTB",
"entity_type": "gene"
},
{
"created": "2021-02-18T17:33:35.463315+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.1",
"user_name": "Mathew Wallis",
"item_type": "entity",
"text": "edited their review of gene: PIK3R2: Changed publications: PMID: 22729224",
"entity_name": "PIK3R2",
"entity_type": "gene"
},
{
"created": "2021-02-18T17:33:22.600609+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.1",
"user_name": "Mathew Wallis",
"item_type": "entity",
"text": "edited their review of gene: PIK3R2: Changed publications: PMID: 22729224, PMID: 22729224",
"entity_name": "PIK3R2",
"entity_type": "gene"
},
{
"created": "2021-02-18T17:33:04.783337+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.1",
"user_name": "Mathew Wallis",
"item_type": "entity",
"text": "gene: AKT3 was added\ngene: AKT3 was added to Mosaic skin disorders. Sources: Literature\nMode of inheritance for gene: AKT3 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: AKT3 were set to PMID: 22729224\nReview for gene: AKT3 was set to GREEN\nAdded comment: Sources: Literature",
"entity_name": "AKT3",
"entity_type": "gene"
},
{
"created": "2021-02-18T17:29:36.397841+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.1",
"user_name": "Mathew Wallis",
"item_type": "entity",
"text": "changed review comment from: Sources: Literature, Expert Review; to: Sources: Literature",
"entity_name": "TSC2",
"entity_type": "gene"
},
{
"created": "2021-02-18T17:29:24.736081+11:00",
"panel_name": "Mosaic skin disorders",
"panel_id": 3472,
"panel_version": "0.1",
"user_name": "Mathew Wallis",
"item_type": "entity",
"text": "changed review comment from: Sources: Expert Review, Literature; to: Sources: Literature",
"entity_name": "TSC1",
"entity_type": "gene"
}
]
}