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{
"count": 221304,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1680",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1678",
"results": [
{
"created": "2020-08-09T20:58:57.820587+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.157",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: SLC30A10: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Hypermanganesemia with dystonia 1, MIM# 613280; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "SLC30A10",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:53:46.441847+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.157",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: POLG as ready",
"entity_name": "POLG",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:53:46.432660+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.157",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: polg has been classified as Red List (Low Evidence).",
"entity_name": "POLG",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:53:40.731592+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.157",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: POLG were changed from to Mitochondrial DNA depletion syndrome 4A (Alpers type), MIM# 203700",
"entity_name": "POLG",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:53:14.188240+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.156",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: POLG was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "POLG",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:52:53.839754+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.155",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: POLG as Red List (low evidence)",
"entity_name": "POLG",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:52:53.829817+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.155",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: polg has been classified as Red List (Low Evidence).",
"entity_name": "POLG",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:52:16.456708+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.154",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: POLG: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Mitochondrial DNA depletion syndrome 4A (Alpers type), MIM# 203700; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "POLG",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:48:33.580386+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.154",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PKHD1 as ready",
"entity_name": "PKHD1",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:48:33.570393+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.154",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pkhd1 has been classified as Green List (High Evidence).",
"entity_name": "PKHD1",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:48:14.165922+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.154",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PKHD1 were changed from to Polycystic kidney disease 4, with or without hepatic disease, MIM# 263200",
"entity_name": "PKHD1",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:47:42.982459+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.153",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PKHD1 were set to ",
"entity_name": "PKHD1",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:47:20.697502+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.152",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PKHD1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PKHD1",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:46:53.066646+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.151",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PKHD1: Rating: GREEN; Mode of pathogenicity: None; Publications: 30366773, 25771912, 8616994; Phenotypes: Polycystic kidney disease 4, with or without hepatic disease, MIM# 263200; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PKHD1",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:42:37.266664+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.151",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PEX7 as ready",
"entity_name": "PEX7",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:42:37.255913+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.151",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex7 has been classified as Red List (Low Evidence).",
"entity_name": "PEX7",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:42:30.185065+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.151",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PEX7 were changed from to Peroxisome biogenesis disorder 2A (Zellweger), MIM# 214110",
"entity_name": "PEX7",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:42:16.418673+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.150",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX7 was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX7",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:41:59.028319+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.150",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX7 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX7",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:41:34.540323+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.149",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PEX7 as Red List (low evidence)",
"entity_name": "PEX7",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:41:34.532547+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.149",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex7 has been classified as Red List (Low Evidence).",
"entity_name": "PEX7",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:41:11.821463+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.148",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PEX7: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Peroxisome biogenesis disorder 2A (Zellweger), MIM# 214110; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX7",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:39:35.838894+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.148",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PEX5 as ready",
"entity_name": "PEX5",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:39:35.828512+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.148",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex5 has been classified as Red List (Low Evidence).",
"entity_name": "PEX5",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:39:31.987374+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.148",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PEX5 were changed from to Peroxisome biogenesis disorder 10A (Zellweger), MIM# 614882",
"entity_name": "PEX5",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:39:09.639062+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.147",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX5",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:38:49.438912+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.146",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PEX5 as Red List (low evidence)",
"entity_name": "PEX5",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:38:49.430440+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.146",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex5 has been classified as Red List (Low Evidence).",
"entity_name": "PEX5",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:38:26.687252+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.145",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PEX5: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Peroxisome biogenesis disorder 10A (Zellweger), MIM# 614882; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX5",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:36:41.846236+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.145",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PEX3 as ready",
"entity_name": "PEX3",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:36:41.837644+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.145",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex3 has been classified as Red List (Low Evidence).",
"entity_name": "PEX3",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:36:39.549597+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.145",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PEX3 were changed from to Peroxisome biogenesis disorder 12A (Zellweger), MIM# 614886",
"entity_name": "PEX3",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:36:17.475021+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.144",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX3",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:35:49.535144+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.143",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PEX3 as Red List (low evidence)",
"entity_name": "PEX3",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:35:49.524501+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.143",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex3 has been classified as Red List (Low Evidence).",
"entity_name": "PEX3",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:35:23.227803+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.142",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PEX3: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Peroxisome biogenesis disorder 12A (Zellweger), MIM# 614886; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX3",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:32:15.150594+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.142",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PEX19 as ready",
"entity_name": "PEX19",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:32:15.140944+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.142",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex19 has been classified as Red List (Low Evidence).",
"entity_name": "PEX19",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:32:12.251462+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.142",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PEX19 were changed from to Peroxisome biogenesis disorder 8A (Zellweger), MIM# 614876",
"entity_name": "PEX19",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:31:36.548760+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.141",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PEX19 were set to ",
"entity_name": "PEX19",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:31:16.485852+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.140",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX19 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX19",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:30:54.476926+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.139",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PEX19 as Red List (low evidence)",
"entity_name": "PEX19",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:30:54.468261+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.139",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex19 has been classified as Red List (Low Evidence).",
"entity_name": "PEX19",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:30:31.513985+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.138",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PEX19: Rating: RED; Mode of pathogenicity: None; Publications: 20683989; Phenotypes: Peroxisome biogenesis disorder 8A (Zellweger), MIM# 614876; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX19",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:26:12.166449+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.138",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PEX16 as Red List (low evidence)",
"entity_name": "PEX16",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:26:12.158760+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.138",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex16 has been classified as Red List (Low Evidence).",
"entity_name": "PEX16",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:25:50.152750+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.137",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PEX16 as ready",
"entity_name": "PEX16",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:25:50.144400+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.137",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex16 has been classified as Green List (High Evidence).",
"entity_name": "PEX16",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:25:47.193977+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.137",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PEX16 were changed from to Peroxisome biogenesis disorder 13A (Zellweger), MIM# 614887",
"entity_name": "PEX16",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:25:19.538947+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.136",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX16 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX16",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:24:53.180974+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.135",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PEX16: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Peroxisome biogenesis disorder 13A (Zellweger), MIM# 614887; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX16",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:23:16.306906+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.135",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PEX14 as ready",
"entity_name": "PEX14",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:23:16.297133+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.135",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex14 has been classified as Amber List (Moderate Evidence).",
"entity_name": "PEX14",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:22:46.456917+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.135",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PEX14 were changed from to Peroxisome biogenesis disorder 13A (Zellweger), MIM# 614887",
"entity_name": "PEX14",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:22:19.620685+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.134",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PEX14 were set to ",
"entity_name": "PEX14",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:21:59.438897+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.133",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX14 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX14",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:21:24.274310+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.132",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PEX14 as Amber List (moderate evidence)",
"entity_name": "PEX14",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:21:24.265868+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.132",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex14 has been classified as Amber List (Moderate Evidence).",
"entity_name": "PEX14",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:21:03.011945+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.131",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PEX14: Rating: AMBER; Mode of pathogenicity: None; Publications: 21686775, 18285423; Phenotypes: Peroxisome biogenesis disorder 13A (Zellweger), MIM# 614887; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX14",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:18:56.970394+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.131",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PEX13 as ready",
"entity_name": "PEX13",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:18:56.959827+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.131",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex13 has been classified as Red List (Low Evidence).",
"entity_name": "PEX13",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:18:53.933935+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.131",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PEX13 were changed from to Peroxisome biogenesis disorder 11A (Zellweger), MIM# 614883",
"entity_name": "PEX13",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:18:31.652914+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.130",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX13 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX13",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:18:07.051490+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.129",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PEX13 as Red List (low evidence)",
"entity_name": "PEX13",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:18:07.041987+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.129",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex13 has been classified as Red List (Low Evidence).",
"entity_name": "PEX13",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:17:43.590009+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.128",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PEX13: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Peroxisome biogenesis disorder 11A (Zellweger), MIM# 614883; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX13",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:15:39.422434+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.128",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PEX11B as ready",
"entity_name": "PEX11B",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:15:39.413544+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.128",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex11b has been classified as Red List (Low Evidence).",
"entity_name": "PEX11B",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:15:36.618532+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.128",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PEX11B were changed from to Peroxisome biogenesis disorder 14B, MIM# 614920",
"entity_name": "PEX11B",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:15:10.375229+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.127",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PEX11B was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX11B",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:14:45.524277+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.126",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PEX11B as Red List (low evidence)",
"entity_name": "PEX11B",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:14:45.514098+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.126",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pex11b has been classified as Red List (Low Evidence).",
"entity_name": "PEX11B",
"entity_type": "gene"
},
{
"created": "2020-08-09T20:14:19.503840+10:00",
"panel_name": "Cholestasis",
"panel_id": 78,
"panel_version": "0.125",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PEX11B: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Peroxisome biogenesis disorder 14B, MIM# 614920; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PEX11B",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:05:49.105393+10:00",
"panel_name": "Melanoma",
"panel_id": 3279,
"panel_version": "0.1",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Panel types changed to Cancer Germline; SA Pathology",
"entity_name": null,
"entity_type": null
},
{
"created": "2020-08-09T18:04:33.219152+10:00",
"panel_name": "Medulloblastoma",
"panel_id": 3280,
"panel_version": "0.1",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Panel types changed to Cancer Germline; SA Pathology",
"entity_name": null,
"entity_type": null
},
{
"created": "2020-08-09T18:01:37.377898+10:00",
"panel_name": "Medulloblastoma",
"panel_id": 3280,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: PHOX2B was added\ngene: PHOX2B was added to Medulloblastoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: PHOX2B was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PHOX2B",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:37.334264+10:00",
"panel_name": "Medulloblastoma",
"panel_id": 3280,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: ALK was added\ngene: ALK was added to Medulloblastoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: ALK was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "ALK",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:37.290560+10:00",
"panel_name": "Medulloblastoma",
"panel_id": 3280,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: TP53 was added\ngene: TP53 was added to Medulloblastoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: TP53 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TP53",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:37.247000+10:00",
"panel_name": "Medulloblastoma",
"panel_id": 3280,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: SUFU was added\ngene: SUFU was added to Medulloblastoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: SUFU was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "SUFU",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:37.198837+10:00",
"panel_name": "Medulloblastoma",
"panel_id": 3280,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: PTCH1 was added\ngene: PTCH1 was added to Medulloblastoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: PTCH1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PTCH1",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:37.155496+10:00",
"panel_name": "Medulloblastoma",
"panel_id": 3280,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: APC was added\ngene: APC was added to Medulloblastoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: APC was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "APC",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:37.108952+10:00",
"panel_name": "Melanoma",
"panel_id": 3279,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: CDKN2A was added\ngene: CDKN2A was added to Melanoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: CDKN2A was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CDKN2A",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:37.066139+10:00",
"panel_name": "Melanoma",
"panel_id": 3279,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: CDK4 was added\ngene: CDK4 was added to Melanoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: CDK4 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: CDK4 were set to Melanoma, cutaneous malignant, MIM#609408",
"entity_name": "CDK4",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:37.015889+10:00",
"panel_name": "Melanoma",
"panel_id": 3279,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: BAP1 was added\ngene: BAP1 was added to Melanoma. Sources: SA Pathology,Expert Review Green\nMode of inheritance for gene: BAP1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: BAP1 were set to Tumour predisposition syndrome, MIM#614327",
"entity_name": "BAP1",
"entity_type": "gene"
},
{
"created": "2020-08-09T18:01:36.479775+10:00",
"panel_name": "Medulloblastoma",
"panel_id": 3280,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Added panel Medulloblastoma",
"entity_name": null,
"entity_type": null
},
{
"created": "2020-08-09T18:01:36.471767+10:00",
"panel_name": "Melanoma",
"panel_id": 3279,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Added panel Melanoma",
"entity_name": null,
"entity_type": null
},
{
"created": "2020-08-09T17:37:51.063959+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.2835",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SLC5A6 were changed from Developmental delay; epilepsy; neurodegeneration to Developmental delay; epilepsy; neurodegeneration; Neurodegeneration, infantile-onset, biotin-responsive, MIM#\t618973",
"entity_name": "SLC5A6",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:37:16.426444+10:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.130",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SLC5A6 were changed from Developmental delay; epilepsy; neurodegeneration to Developmental delay; epilepsy; neurodegeneration; Neurodegeneration, infantile-onset, biotin-responsive, MIM#\t618973",
"entity_name": "SLC5A6",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:36:47.419405+10:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.129",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: SLC5A6: Changed phenotypes: Developmental delay, epilepsy, neurodegeneration, Neurodegeneration, infantile-onset, biotin-responsive, MIM# 618973",
"entity_name": "SLC5A6",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:36:32.779868+10:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "0.774",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SLC5A6 were changed from Developmental delay; epilepsy; neurodegeneration to Developmental delay; epilepsy; neurodegeneration; Neurodegeneration, infantile-onset, biotin-responsive, MIM#\t618973",
"entity_name": "SLC5A6",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:35:47.878748+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3737",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SLC5A6 were changed from Developmental delay; epilepsy; neurodegeneration to Developmental delay; epilepsy; neurodegeneration; Neurodegeneration, infantile-onset, biotin-responsive, MIM#\t618973",
"entity_name": "SLC5A6",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:35:31.369947+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: SLC5A6: Changed phenotypes: Developmental delay, epilepsy, neurodegeneration, Neurodegeneration, infantile-onset, biotin-responsive, MIM# 618973",
"entity_name": "SLC5A6",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:34:37.943590+10:00",
"panel_name": "Polydactyly",
"panel_id": 159,
"panel_version": "0.170",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SMO were changed from Microcephaly, congenital heart disease, polydactyly, aganglionosis; Curry-Jones syndrome, somatic mosaic 601707 to Microcephaly, congenital heart disease, polydactyly, aganglionosis; Pallister-Hall-like syndrome\t, MIM#241800; Curry-Jones syndrome, somatic mosaic 601707",
"entity_name": "SMO",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:33:57.721666+10:00",
"panel_name": "Polydactyly",
"panel_id": 159,
"panel_version": "0.169",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: SMO: Changed phenotypes: Microcephaly, congenital heart disease, polydactyly, aganglionosis, Pallister-Hall-like syndrome, MIM# 241800, Curry-Jones syndrome, somatic mosaic 601707",
"entity_name": "SMO",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:33:07.427870+10:00",
"panel_name": "Microcephaly",
"panel_id": 138,
"panel_version": "0.148",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SMO were changed from Microcephaly, congenital heart disease, polydactyly, aganglionosis to Microcephaly, congenital heart disease, polydactyly, aganglionosis; Pallister-Hall-like syndrome\t, MIM#241800",
"entity_name": "SMO",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:32:16.006381+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SMO were changed from Microcephaly, congenital heart disease, polydactyly, aganglionosis; Curry-Jones syndrome, somatic mosaic 601707 to Microcephaly, congenital heart disease, polydactyly, aganglionosis, Pallister-Hall-like syndrome, MIM#\t241800; Curry-Jones syndrome, somatic mosaic 601707",
"entity_name": "SMO",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:31:37.954434+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3735",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: SMO: Changed phenotypes: Microcephaly, congenital heart disease, polydactyly, aganglionosis, Pallister-Hall-like syndrome, MIM# 241800, Curry-Jones syndrome, somatic mosaic 601707",
"entity_name": "SMO",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:31:02.853576+10:00",
"panel_name": "Hirschsprung disease",
"panel_id": 110,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SMO were changed from Microcephaly, congenital heart disease, polydactyly, aganglionosis to Microcephaly, congenital heart disease, polydactyly, aganglionosis; Pallister-Hall-like syndrome\t, MIM#241800",
"entity_name": "SMO",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:30:38.425965+10:00",
"panel_name": "Hirschsprung disease",
"panel_id": 110,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: SMO: Changed phenotypes: Microcephaly, congenital heart disease, polydactyly, aganglionosis, Pallister-Hall-like syndrome , MIM#241800",
"entity_name": "SMO",
"entity_type": "gene"
},
{
"created": "2020-08-09T17:30:20.841319+10:00",
"panel_name": "Craniosynostosis",
"panel_id": 93,
"panel_version": "0.135",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag somatic tag was added to gene: SMO.",
"entity_name": "SMO",
"entity_type": "gene"
}
]
}