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{
"count": 221304,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1710",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1708",
"results": [
{
"created": "2020-07-27T18:10:07.287711+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: FOXE3 as Red List (low evidence)",
"entity_name": "FOXE3",
"entity_type": "gene"
},
{
"created": "2020-07-27T18:10:07.278689+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: foxe3 has been classified as Red List (Low Evidence).",
"entity_name": "FOXE3",
"entity_type": "gene"
},
{
"created": "2020-07-27T18:09:43.580644+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: FOXE3: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Anterior segment dysgenesis 2, multiple subtypes, MIM# 610256; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "FOXE3",
"entity_type": "gene"
},
{
"created": "2020-07-27T18:06:19.171176+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CYP4V2 as ready",
"entity_name": "CYP4V2",
"entity_type": "gene"
},
{
"created": "2020-07-27T18:06:19.161062+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cyp4v2 has been classified as Green List (High Evidence).",
"entity_name": "CYP4V2",
"entity_type": "gene"
},
{
"created": "2020-07-27T18:05:37.432145+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CYP4V2 were changed from to Bietti crystalline corneoretinal dystrophy, MIM# 210370",
"entity_name": "CYP4V2",
"entity_type": "gene"
},
{
"created": "2020-07-27T18:05:11.928524+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CYP4V2 were set to ",
"entity_name": "CYP4V2",
"entity_type": "gene"
},
{
"created": "2020-07-27T18:04:47.637515+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CYP4V2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CYP4V2",
"entity_type": "gene"
},
{
"created": "2020-07-27T18:04:23.905594+10:00",
"panel_name": "Corneal Dystrophy",
"panel_id": 91,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CYP4V2: Rating: GREEN; Mode of pathogenicity: None; Publications: 15042513; Phenotypes: Bietti crystalline corneoretinal dystrophy, MIM# 210370; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CYP4V2",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:26:02.697245+10:00",
"panel_name": "Hereditary Haemorrhagic Telangiectasia",
"panel_id": 260,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RASA1 as ready",
"entity_name": "RASA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:26:02.691419+10:00",
"panel_name": "Hereditary Haemorrhagic Telangiectasia",
"panel_id": 260,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Similarly to EPHB4, phenotypic overlap with HHT.",
"entity_name": "RASA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:26:02.649045+10:00",
"panel_name": "Hereditary Haemorrhagic Telangiectasia",
"panel_id": 260,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rasa1 has been classified as Green List (High Evidence).",
"entity_name": "RASA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:25:44.580429+10:00",
"panel_name": "Hereditary Haemorrhagic Telangiectasia",
"panel_id": 260,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RASA1 were set to ",
"entity_name": "RASA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:12:32.778039+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.25",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SPINK1 as ready",
"entity_name": "SPINK1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:12:32.766887+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.25",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: spink1 has been classified as Green List (High Evidence).",
"entity_name": "SPINK1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:12:12.505816+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.25",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SPINK1 were changed from to Tropical calcific pancreatitis, MIM# 608189; Pancreatitis, hereditary, MIM# 167800",
"entity_name": "SPINK1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:11:47.532153+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.24",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: SPINK1 were set to ",
"entity_name": "SPINK1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:11:26.900014+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.23",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: SPINK1 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "SPINK1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:10:22.230536+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.22",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: SPINK1: Rating: GREEN; Mode of pathogenicity: None; Publications: 10835640, 11355022, 11938439, 16823394, 17274009, 27535533; Phenotypes: Tropical calcific pancreatitis, MIM# 608189, Pancreatitis, hereditary, MIM# 167800; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "SPINK1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:07:18.659222+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.22",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PRSS1 as ready",
"entity_name": "PRSS1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:07:18.648996+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.22",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: prss1 has been classified as Green List (High Evidence).",
"entity_name": "PRSS1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:07:15.972960+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.22",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PRSS1 were changed from to Pancreatitis, hereditary, MIM# 167800",
"entity_name": "PRSS1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:06:51.168247+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.21",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PRSS1 were set to ",
"entity_name": "PRSS1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:06:01.463834+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.20",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PRSS1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PRSS1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:05:38.988611+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PRSS1: Rating: GREEN; Mode of pathogenicity: None; Publications: 8841182, 10204851, 10529393, 11097832, 11702203, 15776435, 16791840, 18461367, 17072318; Phenotypes: Pancreatitis, hereditary, MIM# 167800; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PRSS1",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:03:39.658482+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CFTR as ready",
"entity_name": "CFTR",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:03:39.647825+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cftr has been classified as Green List (High Evidence).",
"entity_name": "CFTR",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:03:36.691716+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CFTR were changed from to Cystic fibrosis",
"entity_name": "CFTR",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:03:08.660429+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.18",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CFTR was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CFTR",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:02:45.895377+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.17",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CFTR: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Cystic fibrosis; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CFTR",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:00:01.906006+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3536",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CTRC as ready",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T14:00:01.894819+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3536",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ctrc has been classified as Amber List (Moderate Evidence).",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:59:55.576300+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3536",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CTRC were changed from to {Pancreatitis, chronic, susceptibility to}, MIM#167800",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:59:37.755232+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3535",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CTRC were set to ",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:59:19.896236+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3534",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CTRC was changed from Unknown to Other",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:59:04.953801+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3533",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CTRC as Amber List (moderate evidence)",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:59:04.939155+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3533",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ctrc has been classified as Amber List (Moderate Evidence).",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:58:48.833256+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3532",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CTRC: Rating: AMBER; Mode of pathogenicity: None; Publications: 18059268, 18172691, 28502372; Phenotypes: {Pancreatitis, chronic, susceptibility to}, MIM#167800; Mode of inheritance: Other",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:57:48.479820+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.17",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CTRC as ready",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:57:48.469212+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.17",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ctrc has been classified as Amber List (Moderate Evidence).",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:57:44.829658+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.17",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CTRC were changed from to {Pancreatitis, chronic, susceptibility to}, MIM#167800",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:57:19.698010+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.16",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CTRC were set to ",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:56:57.431432+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.15",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CTRC was changed from Unknown to Other",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:56:34.369037+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.14",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CTRC as Amber List (moderate evidence)",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:56:34.360443+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.14",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ctrc has been classified as Amber List (Moderate Evidence).",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T13:56:11.239063+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CTRC: Rating: AMBER; Mode of pathogenicity: None; Publications: 18059268, 18172691, 28502372; Phenotypes: {Pancreatitis, chronic, susceptibility to}, MIM#167800; Mode of inheritance: Other",
"entity_name": "CTRC",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:44:10.683420+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3532",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CPA1 as ready",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:44:10.673851+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3532",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cpa1 has been classified as Green List (High Evidence).",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:44:02.617980+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3532",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CPA1 were changed from to Susceptibility to chronic pancreatitis; Hereditary pancreatitis",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:43:44.660251+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3531",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CPA1 were set to ",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:43:26.713319+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3530",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CPA1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:43:08.930006+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3529",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CPA1: Rating: GREEN; Mode of pathogenicity: None; Publications: 23955596, 28497564, 28258133, 31005883; Phenotypes: Susceptibility to chronic pancreatitis, Hereditary pancreatitis; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:42:14.832522+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CPA1 as ready",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:42:14.820200+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cpa1 has been classified as Green List (High Evidence).",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:42:11.030272+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CPA1 were changed from to Susceptibility to chronic pancreatitis; Hereditary pancreatitis",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:41:47.580429+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.12",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CPA1 were set to ",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:41:24.933946+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CPA1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T12:40:58.238701+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CPA1: Rating: GREEN; Mode of pathogenicity: None; Publications: 23955596, 28497564, 28258133, 31005883; Phenotypes: Susceptibility to chronic pancreatitis, Hereditary pancreatitis; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CPA1",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:53:51.568847+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3529",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CLDN2 as ready",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:53:51.560565+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3529",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cldn2 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:53:45.517197+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3529",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CLDN2 were changed from to Susceptibility to pancreatitis",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:53:31.119109+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3528",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CLDN2 were set to ",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:53:14.189403+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3527",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CLDN2 was changed from Unknown to Other",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:52:54.996076+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3526",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CLDN2 as Amber List (moderate evidence)",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:52:54.984940+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3526",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cldn2 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:52:37.585507+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.3525",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CLDN2: Rating: AMBER; Mode of pathogenicity: None; Publications: 29884332, 31163246; Phenotypes: Susceptibility to pancreatitis; Mode of inheritance: Other",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:51:32.559402+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CLDN2 as ready",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:51:32.550786+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cldn2 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:51:29.675885+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CLDN2 were changed from to Susceptibility to pancreatitis",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:51:09.692627+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CLDN2 were set to ",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:50:48.928897+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.8",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CLDN2 was changed from Unknown to Other",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:50:23.292842+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CLDN2 as Amber List (moderate evidence)",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:50:23.282161+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cldn2 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:49:56.633139+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CLDN2: Rating: AMBER; Mode of pathogenicity: None; Publications: 29884332, 31163246; Phenotypes: Susceptibility to pancreatitis; Mode of inheritance: Other",
"entity_name": "CLDN2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:43:31.674689+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "panel",
"text": "Panel types changed to Victorian Clinical Genetics Services; Rare Disease",
"entity_name": null,
"entity_type": null
},
{
"created": "2020-07-27T11:41:58.328957+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CASR as ready",
"entity_name": "CASR",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:41:58.321146+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: casr has been classified as Amber List (Moderate Evidence).",
"entity_name": "CASR",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:41:55.150942+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CASR were changed from to Susceptibility to pancreatitis",
"entity_name": "CASR",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:41:28.912144+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CASR were set to ",
"entity_name": "CASR",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:41:05.321189+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CASR was changed from Unknown to Other",
"entity_name": "CASR",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:40:45.289880+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CASR as Amber List (moderate evidence)",
"entity_name": "CASR",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:40:45.280138+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: casr has been classified as Amber List (Moderate Evidence).",
"entity_name": "CASR",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:40:17.298891+10:00",
"panel_name": "Pancreatitis",
"panel_id": 154,
"panel_version": "0.1",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CASR: Rating: AMBER; Mode of pathogenicity: None; Publications: 16497624, 26166472; Phenotypes: Susceptibility to pancreatitis; Mode of inheritance: Other",
"entity_name": "CASR",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:22:09.947291+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: ABCC8 as ready",
"entity_name": "ABCC8",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:22:09.935851+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: abcc8 has been classified as Green List (High Evidence).",
"entity_name": "ABCC8",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:21:50.932098+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: ACVRL1 as ready",
"entity_name": "ACVRL1",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:21:50.917420+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: acvrl1 has been classified as Green List (High Evidence).",
"entity_name": "ACVRL1",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:21:29.545324+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: BMPR2 as ready",
"entity_name": "BMPR2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:21:29.537215+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: bmpr2 has been classified as Green List (High Evidence).",
"entity_name": "BMPR2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:21:09.593454+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: ENG as ready",
"entity_name": "ENG",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:21:09.582520+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: eng has been classified as Green List (High Evidence).",
"entity_name": "ENG",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:21:06.577133+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.55",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: ENG were changed from Telangiectasia, hereditary hemorrhagic, type 1 MIM#187300 to Telangiectasia, hereditary hemorrhagic, type 1 MIM#187300; Pulmonary arterial hypertension",
"entity_name": "ENG",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:20:58.466113+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.54",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: ENG were set to ",
"entity_name": "ENG",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:20:35.370600+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GDF2 as ready",
"entity_name": "GDF2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:20:35.361733+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gdf2 has been classified as Green List (High Evidence).",
"entity_name": "GDF2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:20:32.992995+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: GDF2 were changed from Telangiectasia, hereditary hemorrhagic, type 5 MIM#615506 to Telangiectasia, hereditary hemorrhagic, type 5 MIM#615506; Pulmonary arterial hypertension",
"entity_name": "GDF2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:20:23.793388+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.52",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: GDF2 were set to ",
"entity_name": "GDF2",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:19:54.122845+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KCNK3 as ready",
"entity_name": "KCNK3",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:19:54.080218+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kcnk3 has been classified as Green List (High Evidence).",
"entity_name": "KCNK3",
"entity_type": "gene"
},
{
"created": "2020-07-27T11:19:32.417710+10:00",
"panel_name": "Pulmonary Arterial Hypertension",
"panel_id": 3095,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SMAD9 as ready",
"entity_name": "SMAD9",
"entity_type": "gene"
}
]
}