HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 221415,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1779",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=1777",
"results": [
{
"created": "2020-06-01T20:04:54.485831+10:00",
"panel_name": "Long QT Syndrome",
"panel_id": 131,
"panel_version": "0.36",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: KCNJ5 as Red List (low evidence)",
"entity_name": "KCNJ5",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:04:54.476755+10:00",
"panel_name": "Long QT Syndrome",
"panel_id": 131,
"panel_version": "0.36",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kcnj5 has been classified as Red List (Low Evidence).",
"entity_name": "KCNJ5",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:02:53.404391+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.95",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NPHP4 as ready",
"entity_name": "NPHP4",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:02:53.394058+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.95",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nphp4 has been classified as Amber List (Moderate Evidence).",
"entity_name": "NPHP4",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:02:53.041998+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.95",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NPHP4 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "NPHP4",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:02:32.646097+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.95",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NPHP4 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "NPHP4",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:02:01.289733+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.94",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NPHP4 as Amber List (moderate evidence)",
"entity_name": "NPHP4",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:02:01.276181+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.94",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nphp4 has been classified as Amber List (Moderate Evidence).",
"entity_name": "NPHP4",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:00:19.542577+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NKX2-5 as ready",
"entity_name": "NKX2-5",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:00:19.533735+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nkx2-5 has been classified as Green List (High Evidence).",
"entity_name": "NKX2-5",
"entity_type": "gene"
},
{
"created": "2020-06-01T20:00:05.660837+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NKX2-5 were changed from to Ventricular septal defect 3 (MIM#614432); Tetralogy of Fallot (MIM#187500)",
"entity_name": "NKX2-5",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:59:17.336656+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.44",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NKX2-5 were set to ",
"entity_name": "NKX2-5",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:58:54.480745+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.43",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NKX2-5 was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NKX2-5",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:58:34.342771+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.43",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NKX2-5 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NKX2-5",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:05:14.872578+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.93",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CCNO as ready",
"entity_name": "CCNO",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:05:14.862336+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.93",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ccno has been classified as Red List (Low Evidence).",
"entity_name": "CCNO",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:05:11.631823+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.93",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CCNO were changed from to Ciliary dyskinesia, primary, 29, MIM# 615872",
"entity_name": "CCNO",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:04:40.300840+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.92",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CCNO were set to ",
"entity_name": "CCNO",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:04:11.506741+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.91",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CCNO was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CCNO",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:03:44.862715+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.90",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CCNO as Red List (low evidence)",
"entity_name": "CCNO",
"entity_type": "gene"
},
{
"created": "2020-06-01T19:03:44.853713+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.90",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ccno has been classified as Red List (Low Evidence).",
"entity_name": "CCNO",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:41:36.780163+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.89",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CRELD1 as Amber List (moderate evidence)",
"entity_name": "CRELD1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:41:36.767285+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.89",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: creld1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CRELD1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:41:06.044466+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "changed review comment from: Three families reported with heterozygous missense variants and heterotaxy phenotype. \nSources: Expert list; to: Three families reported with heterozygous missense variants and heterotaxy phenotype. However, supporting evidence of pathogenicity for some of the variants is relatively weak.\r\nSources: Expert list",
"entity_name": "CRELD1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:40:39.966850+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: CRELD1: Changed rating: AMBER",
"entity_name": "CRELD1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:35:47.892945+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DNAAF2 as ready",
"entity_name": "DNAAF2",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:35:47.881053+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dnaaf2 has been classified as Green List (High Evidence).",
"entity_name": "DNAAF2",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:35:44.698983+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DNAAF2 were changed from to Ciliary dyskinesia, primary, 10 612518",
"entity_name": "DNAAF2",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:35:17.106820+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.87",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: DNAAF2 were set to ",
"entity_name": "DNAAF2",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:34:54.118475+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.86",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: DNAAF2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "DNAAF2",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:29:54.173823+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.85",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DNAH1 as ready",
"entity_name": "DNAH1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:29:54.163692+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.85",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dnah1 has been classified as Red List (Low Evidence).",
"entity_name": "DNAH1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:29:48.608264+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.85",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DNAH1 as Red List (low evidence)",
"entity_name": "DNAH1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:29:48.599245+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.85",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dnah1 has been classified as Red List (Low Evidence).",
"entity_name": "DNAH1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:26:32.368163+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2985",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DNAH6 as ready",
"entity_name": "DNAH6",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:26:32.354415+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2985",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dnah6 has been classified as Amber List (Moderate Evidence).",
"entity_name": "DNAH6",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:25:55.947062+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2985",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DNAH6 as Amber List (moderate evidence)",
"entity_name": "DNAH6",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:25:55.937628+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2985",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dnah6 has been classified as Amber List (Moderate Evidence).",
"entity_name": "DNAH6",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:25:10.663478+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.109",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DNAH9 as ready",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:25:10.648764+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.109",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dnah9 has been classified as Green List (High Evidence).",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:25:03.168137+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.109",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DNAH9 were changed from to Ciliary dyskinesia, primary, 40, MIM# 618300",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:24:38.831049+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.108",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: DNAH9 were set to ",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:24:14.018183+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.107",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: DNAH9 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:23:44.082704+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.106",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: DNAH9: Rating: GREEN; Mode of pathogenicity: None; Publications: 30471717, 30471718; Phenotypes: Ciliary dyskinesia, primary, 40, MIM# 618300; Mode of inheritance: None",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:21:57.716543+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DNAH9 as ready",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:21:57.706106+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dnah9 has been classified as Green List (High Evidence).",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:21:51.844098+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DNAH9 as Green List (high evidence)",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:21:51.835051+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dnah9 has been classified as Green List (High Evidence).",
"entity_name": "DNAH9",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:18:07.570732+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2984",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DRC1 as ready",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:18:07.562084+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2984",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: drc1 has been classified as Green List (High Evidence).",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:17:58.422717+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2984",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DRC1 were changed from to Ciliary dyskinesia, primary, 21, MIM# 615294",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:17:34.348375+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2983",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: DRC1 were set to ",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:17:14.834847+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2982",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: DRC1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:16:57.005043+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2981",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag SV/CNV tag was added to gene: DRC1.",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:16:45.549093+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2981",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: DRC1: Changed mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:16:34.038058+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2981",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: DRC1: Rating: GREEN; Mode of pathogenicity: None; Publications: 31960620; Phenotypes: Ciliary dyskinesia, primary, 21, MIM# 615294; Mode of inheritance: None",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:14:56.398728+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DRC1 as ready",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:14:56.386725+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: drc1 has been classified as Red List (Low Evidence).",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:14:53.608376+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DRC1 were changed from to Ciliary dyskinesia, primary, 21, MIM# 615294",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:13:16.081581+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: DRC1 were set to ",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:12:47.103334+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.81",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: DRC1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:10:30.975398+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.80",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DRC1 as Red List (low evidence)",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:10:30.965820+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.80",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: drc1 has been classified as Red List (Low Evidence).",
"entity_name": "DRC1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:07:51.084397+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TLL1 as ready",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:07:51.073380+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tll1 has been classified as Green List (High Evidence).",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:07:47.953541+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TLL1 were set to ",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:06:58.779572+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.41",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TLL1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:06:25.166485+10:00",
"panel_name": "Congenital Heart Defect",
"panel_id": 76,
"panel_version": "0.40",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TLL1: Rating: GREEN; Mode of pathogenicity: None; Publications: 18830233, 30538173, 27418595, 31570783; Phenotypes: Atrial septal defect; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:05:29.256026+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2981",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TLL1 were changed from to Atrial septal defect",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:05:07.571011+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2980",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TLL1 were set to ",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T18:04:05.572941+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2979",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TLL1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T17:52:47.873553+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2978",
"user_name": "Dean Phelan",
"item_type": "entity",
"text": "reviewed gene: TLL1: Rating: GREEN; Mode of pathogenicity: None; Publications: 18830233, 30538173, 27418595, 31570783; Phenotypes: Atrial septal defect; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TLL1",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:58:07.821814+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2978",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HIST1H4J as ready",
"entity_name": "HIST1H4J",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:58:07.811677+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2978",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hist1h4j has been classified as Amber List (Moderate Evidence).",
"entity_name": "HIST1H4J",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:57:59.374169+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2978",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: HIST1H4J as Amber List (moderate evidence)",
"entity_name": "HIST1H4J",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:57:59.360931+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2978",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hist1h4j has been classified as Amber List (Moderate Evidence).",
"entity_name": "HIST1H4J",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:57:41.431953+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2977",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: HIST1H4J was added\ngene: HIST1H4J was added to Mendeliome. Sources: Literature\nMode of inheritance for gene: HIST1H4J was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: HIST1H4J were set to 31804630\nPhenotypes for gene: HIST1H4J were set to microcephaly; intellectual disability; dysmorphic features\nReview for gene: HIST1H4J was set to AMBER\nAdded comment: Single case report but with functional evidence in zebrafish and phenotypic similarity to other HIST1H4C phenotype \nSources: Literature",
"entity_name": "HIST1H4J",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:55:13.799529+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2976",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MCIDAS as ready",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:55:13.790691+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2976",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mcidas has been classified as Green List (High Evidence).",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:55:06.701014+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2976",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MCIDAS were changed from to Ciliary dyskinesia, primary, 42 (MIM#618695)",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:54:44.259956+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2975",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: MCIDAS were set to ",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:54:07.430642+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2974",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: MCIDAS was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:53:48.433087+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2973",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MCIDAS: Rating: GREEN; Mode of pathogenicity: None; Publications: 25048963; Phenotypes: Ciliary dyskinesia, primary, 42 (MIM#618695); Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:52:39.201777+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MCIDAS as ready",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:52:39.187979+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mcidas has been classified as Red List (Low Evidence).",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:52:36.591888+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MCIDAS were changed from to Ciliary dyskinesia, primary, 42 (MIM#618695)",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:51:53.500041+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: MCIDAS were set to ",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:50:30.783165+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.77",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: MCIDAS was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:50:02.281923+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: MCIDAS as Red List (low evidence)",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:50:02.272719+10:00",
"panel_name": "Heterotaxy",
"panel_id": 108,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mcidas has been classified as Red List (Low Evidence).",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:49:24.609961+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.106",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MCIDAS as ready",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:49:24.601307+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.106",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mcidas has been classified as Green List (High Evidence).",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:47:28.611180+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.106",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MCIDAS were changed from to Ciliary dyskinesia, primary, 42 (MIM#618695)",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:45:43.063023+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.105",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: MCIDAS were set to ",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:45:10.172810+10:00",
"panel_name": "Ciliary Dyskinesia",
"panel_id": 82,
"panel_version": "0.104",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: MCIDAS was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "MCIDAS",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:36:15.236372+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2973",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: VWA3B as ready",
"entity_name": "VWA3B",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:36:15.225119+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.2973",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: vwa3b has been classified as Red List (Low Evidence).",
"entity_name": "VWA3B",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:33:07.500750+10:00",
"panel_name": "Muscular dystrophy",
"panel_id": 141,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TOR1AIP1 as ready",
"entity_name": "TOR1AIP1",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:33:07.491531+10:00",
"panel_name": "Muscular dystrophy",
"panel_id": 141,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tor1aip1 has been classified as Green List (High Evidence).",
"entity_name": "TOR1AIP1",
"entity_type": "gene"
},
{
"created": "2020-06-01T16:33:03.330980+10:00",
"panel_name": "Muscular dystrophy",
"panel_id": 141,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TOR1AIP1 as Green List (high evidence)",
"entity_name": "TOR1AIP1",
"entity_type": "gene"
}
]
}