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{
"count": 220725,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2011",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2009",
"results": [
{
"created": "2020-01-03T14:53:08.774471+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.37",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: DCDC2 were set to ",
"entity_name": "DCDC2",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:50:41.166690+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.36",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: DCDC2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "DCDC2",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:50:32.423033+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.35",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DCDC2 as Amber List (moderate evidence)",
"entity_name": "DCDC2",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:50:32.411490+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.35",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: dcdc2 has been classified as Amber List (Moderate Evidence).",
"entity_name": "DCDC2",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:50:20.219001+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.34",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: DCDC2: Rating: AMBER; Mode of pathogenicity: None; Publications: 25557784; Phenotypes: Nephronophthisis 19, MIM# 616217; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "DCDC2",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:49:24.953937+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.34",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Classified gene: CEP120 as Amber List (moderate evidence)",
"entity_name": "CEP120",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:49:24.942740+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.34",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Gene: cep120 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CEP120",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:49:11.247151+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.33",
"user_name": "chirag patel",
"item_type": "entity",
"text": "reviewed gene: CEP120: Rating: AMBER; Mode of pathogenicity: None; Publications: PMID: 25361962; Phenotypes: Joubert syndrome 31, OMIM #617761, Short-rib thoracic dysplasia 13 with or without polydactyly, OMIM #616300; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CEP120",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:42:10.765898+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.33",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Classified gene: C2CD3 as Red List (low evidence)",
"entity_name": "C2CD3",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:42:10.754507+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.33",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Gene: c2cd3 has been classified as Red List (Low Evidence).",
"entity_name": "C2CD3",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:42:00.174696+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.32",
"user_name": "chirag patel",
"item_type": "entity",
"text": "changed review comment from: Renal phenotype not commonly seen in this group.; to: Renal phenotype not commonly seen in this ciliopathy, so not a renal ciliopathy",
"entity_name": "C2CD3",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:41:33.501058+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.32",
"user_name": "chirag patel",
"item_type": "entity",
"text": "reviewed gene: C2CD3: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "C2CD3",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:36:07.849981+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.32",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Classified gene: B9D1 as Red List (low evidence)",
"entity_name": "B9D1",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:36:07.837128+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.32",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Gene: b9d1 has been classified as Red List (Low Evidence).",
"entity_name": "B9D1",
"entity_type": "gene"
},
{
"created": "2020-01-03T14:35:58.974046+11:00",
"panel_name": "Renal ciliopathies and nephronophthisis_KidGen_VCGS",
"panel_id": 193,
"panel_version": "0.31",
"user_name": "chirag patel",
"item_type": "entity",
"text": "reviewed gene: B9D1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ?Meckel syndrome 9, OMIM #614209, Joubert syndrome 27, OMIM #617120; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "B9D1",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:59:49.476136+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CD151 as ready",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:59:49.459190+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cd151 has been classified as Red List (Low Evidence).",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:59:39.946711+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CD151 were changed from to Nephropathy with pretibial epidermolysis bullosa and deafness, MIM#609057",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:57:45.948065+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.12",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CD151 were set to 15265795; 29138120",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:57:20.722798+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CD151 was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:56:53.467474+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.11",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Classified gene: OCRL as Red List (low evidence)",
"entity_name": "OCRL",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:56:53.443423+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.11",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Gene: ocrl has been classified as Red List (Low Evidence).",
"entity_name": "OCRL",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:56:26.707492+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.10",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Classified gene: OCRL as Red List (low evidence)",
"entity_name": "OCRL",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:56:26.675610+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.10",
"user_name": "chirag patel",
"item_type": "entity",
"text": "Gene: ocrl has been classified as Red List (Low Evidence).",
"entity_name": "OCRL",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:56:01.098575+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CD151 as Red List (low evidence)",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:56:01.031574+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cd151 has been classified as Red List (Low Evidence).",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:55:36.843539+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CD151 were set to ",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:55:09.175585+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CD151 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:54:42.652638+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CD151 as Red List (low evidence)",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:54:41.995782+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cd151 has been classified as Red List (Low Evidence).",
"entity_name": "CD151",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:54:39.142269+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.8",
"user_name": "chirag patel",
"item_type": "entity",
"text": "reviewed gene: OCRL: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "OCRL",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:48:42.228097+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.569",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PIGQ as ready",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:48:42.134225+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.569",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pigq has been classified as Green List (High Evidence).",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:47:51.300007+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.569",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PIGQ as Green List (high evidence)",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:47:51.123071+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.569",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pigq has been classified as Green List (High Evidence).",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:47:25.418710+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.568",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: PIGQ was added\ngene: PIGQ was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: PIGQ was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: PIGQ were set to 25558065; 24463883; 31148362\nPhenotypes for gene: PIGQ were set to Epileptic encephalopathy, early infantile, 77, MIM#\t618548\nReview for gene: PIGQ was set to GREEN\nAdded comment: Three unrelated families reported. \nSources: Expert list",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:39:45.879680+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PIGQ as ready",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:39:45.861745+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pigq has been classified as Green List (High Evidence).",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:39:41.444893+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PIGQ as Green List (high evidence)",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:39:41.426008+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pigq has been classified as Green List (High Evidence).",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T13:39:08.468320+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: PIGQ was added\ngene: PIGQ was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: PIGQ was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: PIGQ were set to 25558065; 24463883; 31148362\nPhenotypes for gene: PIGQ were set to Epileptic encephalopathy, early infantile, 77, MIM#\t618548\nReview for gene: PIGQ was set to GREEN\nAdded comment: Three unrelated families reported. \nSources: Expert list",
"entity_name": "PIGQ",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:49:21.130005+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1466",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NTRK2 as ready",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:49:21.119110+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1466",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ntrk2 has been classified as Green List (High Evidence).",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:49:15.439061+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1466",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NTRK2 as Green List (high evidence)",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:49:15.427872+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1466",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ntrk2 has been classified as Green List (High Evidence).",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:49:02.374762+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1465",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NTRK2 was added\ngene: NTRK2 was added to Intellectual disability, syndromic and non-syndromic_GHQ_VCGS. Sources: Expert list\nMode of inheritance for gene: NTRK2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: NTRK2 were set to 15494731; 27884935; 29100083\nPhenotypes for gene: NTRK2 were set to Obesity, hyperphagia, and developmental delay, MIM# 613886\nReview for gene: NTRK2 was set to GREEN\nAdded comment: Three unrelated individuals reported with this phenotype.\r\nNote recurrent missense in this gene also causes EE. \nSources: Expert list",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:47:10.987661+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.567",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NTRK2 as ready",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:47:10.976203+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.567",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ntrk2 has been classified as Green List (High Evidence).",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:47:00.442689+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.567",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NTRK2 were changed from to Epileptic encephalopathy, early infantile, 58, MIM# 617830; Obesity, hyperphagia, and developmental delay, MIM# 613886",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:46:57.730873+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.567",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NTRK2 were set to ",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:46:30.956057+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.566",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NTRK2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:46:11.476005+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.565",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: NTRK2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29100083, 15494731, 27884935, 29100083; Phenotypes: Epileptic encephalopathy, early infantile, 58, MIM# 617830, Obesity, hyperphagia, and developmental delay, MIM# 613886; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:42:34.775197+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NTRK2 as ready",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:42:34.762562+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ntrk2 has been classified as Green List (High Evidence).",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:39:27.658503+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NTRK2 as Green List (high evidence)",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:39:27.646029+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ntrk2 has been classified as Green List (High Evidence).",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:38:49.988353+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.81",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NTRK2 was added\ngene: NTRK2 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: NTRK2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: NTRK2 were set to 29100083\nPhenotypes for gene: NTRK2 were set to Epileptic encephalopathy, early infantile, 58, MIM#\t617830\nReview for gene: NTRK2 was set to GREEN\nAdded comment: Four unrelated individuals with recurrent de novo missense variant in this gene reported. \nSources: Expert list",
"entity_name": "NTRK2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:36:14.266142+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.565",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: ADAM22 was added\ngene: ADAM22 was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: ADAM22 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: ADAM22 were set to 27066583; 30237576\nPhenotypes for gene: ADAM22 were set to Epileptic encephalopathy, early infantile, 61, MIM#\t617933\nReview for gene: ADAM22 was set to AMBER\nAdded comment: Two families reported; the second one as part of a large consanguineous cohort. \nSources: Expert list",
"entity_name": "ADAM22",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:35:20.201131+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.80",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: ADAM22 as Amber List (moderate evidence)",
"entity_name": "ADAM22",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:35:20.187252+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.80",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: adam22 has been classified as Amber List (Moderate Evidence).",
"entity_name": "ADAM22",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:34:32.387932+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: ADAM22 was added\ngene: ADAM22 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: ADAM22 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: ADAM22 were set to 27066583; 30237576\nPhenotypes for gene: ADAM22 were set to Epileptic encephalopathy, early infantile, 61, MIM#\t617933\nReview for gene: ADAM22 was set to AMBER\nAdded comment: Two families reported; the second one as part of a large consanguineous cohort. \nSources: Expert list",
"entity_name": "ADAM22",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:29:55.067928+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.564",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PHACTR1 as ready",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:29:55.055662+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.564",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: phactr1 has been classified as Green List (High Evidence).",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:29:13.718789+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.564",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PHACTR1 as Green List (high evidence)",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:29:13.706011+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.564",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: phactr1 has been classified as Green List (High Evidence).",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:28:56.177856+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.563",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: PHACTR1 was added\ngene: PHACTR1 was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: PHACTR1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: PHACTR1 were set to 30256902\nPhenotypes for gene: PHACTR1 were set to Epileptic encephalopathy, early infantile, 70, MIM#\t618298\nReview for gene: PHACTR1 was set to GREEN\nAdded comment: Three unrelated individuals reported with de novo variants in this gene. \nSources: Expert list",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:28:54.595738+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PHACTR1 as ready",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:28:54.582932+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: phactr1 has been classified as Green List (High Evidence).",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:28:49.440131+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PHACTR1 as Green List (high evidence)",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:28:49.428801+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: phactr1 has been classified as Green List (High Evidence).",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:27:36.676173+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.77",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PHACTR1 as Green List (high evidence)",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:27:36.663483+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.77",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: phactr1 has been classified as Green List (High Evidence).",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:26:53.921085+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: PHACTR1 was added\ngene: PHACTR1 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: PHACTR1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: PHACTR1 were set to 23033978; 30256902\nPhenotypes for gene: PHACTR1 were set to Epileptic encephalopathy, early infantile, 70, MIM#\t618298\nReview for gene: PHACTR1 was set to GREEN\nAdded comment: Three unrelated individuals reported with de novo variants in this gene. \nSources: Expert list",
"entity_name": "PHACTR1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:24:09.930926+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.562",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GABRB1 as ready",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:24:09.919233+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.562",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gabrb1 has been classified as Green List (High Evidence).",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:24:01.134953+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.562",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GABRB1 as Green List (high evidence)",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:24:01.123910+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.562",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gabrb1 has been classified as Green List (High Evidence).",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:23:43.332318+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.561",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: GABRB1 was added\ngene: GABRB1 was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: GABRB1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: GABRB1 were set to 23934111; 27273810; 31618474\nPhenotypes for gene: GABRB1 were set to Epileptic encephalopathy, early infantile, 45, MIM#\t617153\nReview for gene: GABRB1 was set to GREEN\nAdded comment: Three individuals reported, two as part of large epilepsy cohorts. \nSources: Expert list",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:22:58.910901+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GABRB1 as ready",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:22:58.896243+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gabrb1 has been classified as Green List (High Evidence).",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:22:41.632753+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GABRB1 as Green List (high evidence)",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:22:41.620485+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gabrb1 has been classified as Green List (High Evidence).",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:21:18.786220+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: GABRB1 was added\ngene: GABRB1 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: GABRB1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: GABRB1 were set to 23934111; 27273810; 31618474\nPhenotypes for gene: GABRB1 were set to Epileptic encephalopathy, early infantile, 45, MIM#\t617153\nReview for gene: GABRB1 was set to GREEN\nAdded comment: Three individuals reported, two as part of large epilepsy cohorts. \nSources: Expert list",
"entity_name": "GABRB1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:15:01.964463+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.560",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GABRA2 as ready",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:15:01.951738+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.560",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gabra2 has been classified as Green List (High Evidence).",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:14:53.676675+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.560",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: GABRA2 were changed from to Epileptic encephalopathy, early infantile, 78, MIM# 618557",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:14:38.353592+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.559",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: GABRA2 were set to ",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:14:24.328689+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.558",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: GABRA2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:14:05.929880+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.557",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: GABRA2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29422393; Phenotypes: Epileptic encephalopathy, early infantile, 78, MIM# 618557; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:12:56.665287+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GABRA2 as ready",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:12:56.653493+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gabra2 has been classified as Green List (High Evidence).",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:12:50.697133+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GABRA2 as Green List (high evidence)",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:12:50.685082+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gabra2 has been classified as Green List (High Evidence).",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:11:39.688196+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: GABRA2 was added\ngene: GABRA2 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: GABRA2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: GABRA2 were set to 29961870; 31032849; 29422393\nPhenotypes for gene: GABRA2 were set to Epileptic encephalopathy, early infantile, 78, MIM#\t618557\nReview for gene: GABRA2 was set to GREEN\nAdded comment: Five unrelated individuals reported in three publications. \nSources: Expert list",
"entity_name": "GABRA2",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:08:31.102938+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.557",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GUF1 as ready",
"entity_name": "GUF1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:08:31.090420+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.557",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: guf1 has been classified as Red List (Low Evidence).",
"entity_name": "GUF1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:08:21.179351+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.557",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: GUF1 was added\ngene: GUF1 was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: GUF1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: GUF1 were set to 26486472\nPhenotypes for gene: GUF1 were set to Epileptic encephalopathy, early infantile, 40, MIM#\t617065\nReview for gene: GUF1 was set to RED\nAdded comment: Single family reported with homozygous missense in three sibs. \nSources: Expert list",
"entity_name": "GUF1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:06:43.168114+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.71",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GUF1 as ready",
"entity_name": "GUF1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:06:43.155776+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.71",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: guf1 has been classified as Red List (Low Evidence).",
"entity_name": "GUF1",
"entity_type": "gene"
},
{
"created": "2020-01-03T12:06:36.163747+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.71",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: GUF1 was added\ngene: GUF1 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: GUF1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: GUF1 were set to 26486472\nPhenotypes for gene: GUF1 were set to Epileptic encephalopathy, early infantile, 40, MIM#\t617065\nReview for gene: GUF1 was set to RED\nAdded comment: Single family reported with homozygous missense in three sibs. \nSources: Expert list",
"entity_name": "GUF1",
"entity_type": "gene"
}
]
}