HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 220725,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2012",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2010",
"results": [
{
"created": "2020-01-03T10:56:24.966074+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.556",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CPLX1 as ready",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:56:24.954835+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.556",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cplx1 has been classified as Green List (High Evidence).",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:56:14.918211+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.556",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CPLX1 as Green List (high evidence)",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:56:14.906699+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.556",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cplx1 has been classified as Green List (High Evidence).",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:55:57.391600+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.555",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: CPLX1 was added\ngene: CPLX1 was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: CPLX1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: CPLX1 were set to 26539891; 28422131\nPhenotypes for gene: CPLX1 were set to Epileptic encephalopathy, early infantile, 63, MIM#\t617976\nReview for gene: CPLX1 was set to GREEN\nAdded comment: Five individuals from three unrelated families reported in larger neurodevelopmental cohorts. \nSources: Expert list",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:53:51.477771+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.70",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CPLX1 as ready",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:53:51.460849+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.70",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cplx1 has been classified as Green List (High Evidence).",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:53:44.493637+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.70",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CPLX1 as Green List (high evidence)",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:53:44.480247+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.70",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cplx1 has been classified as Green List (High Evidence).",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:53:07.097919+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: CPLX1 was added\ngene: CPLX1 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: CPLX1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: CPLX1 were set to 26539891; 28422131\nPhenotypes for gene: CPLX1 were set to Epileptic encephalopathy, early infantile, 63, MIM#\t617976\nReview for gene: CPLX1 was set to GREEN\nAdded comment: Five individuals from three unrelated families reported in larger neurodevelopmental cohorts. \nSources: Expert list",
"entity_name": "CPLX1",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:48:23.354961+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.41",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RNF13 as ready",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:48:23.344333+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.41",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnf13 has been classified as Green List (High Evidence).",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:48:19.306969+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.41",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: RNF13 as Green List (high evidence)",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:48:19.293793+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.41",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnf13 has been classified as Green List (High Evidence).",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:47:41.089948+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.554",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RNF13 as ready",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:47:41.078209+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.554",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnf13 has been classified as Green List (High Evidence).",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:47:33.530577+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.40",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: RNF13 was added\ngene: RNF13 was added to Regression_VCGS. Sources: Literature\nMode of inheritance for gene: RNF13 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: RNF13 were set to 30595371\nPhenotypes for gene: RNF13 were set to Epileptic encephalopathy, early infantile, 73, MIM#\t618379\nMode of pathogenicity for gene: RNF13 was set to Other\nReview for gene: RNF13 was set to GREEN\nAdded comment: Three unrelated individuals with de novo gain-of-function variants in this gene reported; severe neurodegenerative disorder, seizures are a prominent part of the phenotype. \nSources: Literature",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:47:22.620103+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.554",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: RNF13 as Green List (high evidence)",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:47:22.607940+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.554",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnf13 has been classified as Green List (High Evidence).",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:46:57.614983+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RNF13 as ready",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:46:57.603428+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnf13 has been classified as Green List (High Evidence).",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:46:53.226076+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.553",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: RNF13 was added\ngene: RNF13 was added to Mendeliome_VCGS. Sources: Literature\nMode of inheritance for gene: RNF13 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: RNF13 were set to 30595371\nPhenotypes for gene: RNF13 were set to Epileptic encephalopathy, early infantile, 73, MIM#\t618379\nMode of pathogenicity for gene: RNF13 was set to Other\nReview for gene: RNF13 was set to GREEN\nAdded comment: Three unrelated individuals with de novo gain-of-function variants in this gene reported; severe neurodegenerative disorder, seizures are a prominent part of the phenotype. \nSources: Literature",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:46:26.305505+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: RNF13 as Green List (high evidence)",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:46:26.293664+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnf13 has been classified as Green List (High Evidence).",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:44:12.504437+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: RNF13 as Green List (high evidence)",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:44:12.480490+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnf13 has been classified as Green List (High Evidence).",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:43:07.335652+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.66",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: RNF13 was added\ngene: RNF13 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Literature\nMode of inheritance for gene: RNF13 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: RNF13 were set to 30595371\nPhenotypes for gene: RNF13 were set to Epileptic encephalopathy, early infantile, 73, MIM#\t618379\nMode of pathogenicity for gene: RNF13 was set to Other\nReview for gene: RNF13 was set to GREEN\nAdded comment: Three unrelated individuals with de novo gain-of-function variants in this gene reported; severe neurodegenerative disorder, seizures are a prominent part of the phenotype. \nSources: Literature",
"entity_name": "RNF13",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:39:56.577919+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1464",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GLS as ready",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:39:56.566915+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1464",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gls has been classified as Amber List (Moderate Evidence).",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:39:52.688541+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1464",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GLS as Amber List (moderate evidence)",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:39:52.675539+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1464",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gls has been classified as Amber List (Moderate Evidence).",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:39:29.763114+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1463",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: GLS was added\ngene: GLS was added to Intellectual disability, syndromic and non-syndromic_GHQ_VCGS. Sources: Literature\nMode of inheritance for gene: GLS was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: GLS were set to 30970188\nPhenotypes for gene: GLS were set to Global developmental delay, progressive ataxia, and elevated glutamine, MIM#\t618412\nReview for gene: GLS was set to AMBER\nAdded comment: Three unrelated individuals described with compound het variants, however, note one of these is a triplet expansion in the 5' UTR, this may not be tractable depending on sequencing modality. \nSources: Literature",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:36:00.683753+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.552",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GLS as ready",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:36:00.672107+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.552",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gls has been classified as Green List (High Evidence).",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:35:52.809460+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.552",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GLS as Green List (high evidence)",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:35:52.796875+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.552",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gls has been classified as Green List (High Evidence).",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:35:17.549978+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.551",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: GLS was added\ngene: GLS was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: GLS was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: GLS were set to 30575854; 30970188\nPhenotypes for gene: GLS were set to Epileptic encephalopathy, early infantile, 71, MIM#\t618328; Global developmental delay, progressive ataxia, and elevated glutamine, MIM#\t618412\nReview for gene: GLS was set to GREEN\nAdded comment: Three individuals from two unrelated families reported with early neonatal refractory seizures, structural brain abnormalities and oedema; significantly increased glutamine levels (PMID: 30575854).\r\n\r\nAnother three unrelated individuals described with compound het variants, one of which is a triplet expansion in the 5' UTR (PMID: 30970188). \nSources: Expert list",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:30:17.676279+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GLS as ready",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:30:17.664308+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gls has been classified as Amber List (Moderate Evidence).",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:29:05.878937+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GLS as Amber List (moderate evidence)",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:29:05.850678+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gls has been classified as Amber List (Moderate Evidence).",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:28:28.971040+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: GLS was added\ngene: GLS was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: GLS was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: GLS were set to 30575854\nPhenotypes for gene: GLS were set to Epileptic encephalopathy, early infantile, 71, MIM#\t618328\nReview for gene: GLS was set to AMBER\nAdded comment: Three individuals from two unrelated families reported with early neonatal refractory seizures, structural brain abnormalities and oedema; significantly increased glutamine levels. \nSources: Expert list",
"entity_name": "GLS",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:24:11.389762+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.39",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CAD as ready",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:24:11.378053+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.39",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cad has been classified as Green List (High Evidence).",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:24:06.819833+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.39",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CAD as Green List (high evidence)",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:24:06.808938+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.39",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cad has been classified as Green List (High Evidence).",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:23:32.538175+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.38",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: CAD was added\ngene: CAD was added to Regression_VCGS. Sources: Expert list\nMode of inheritance for gene: CAD was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: CAD were set to 28007989; 25678555\nPhenotypes for gene: CAD were set to Epileptic encephalopathy, early infantile, 50, MIM#\t616457\nReview for gene: CAD was set to GREEN\nAdded comment: Five individuals from four unrelated families reported, seizures are a prominent part of the phenotype of this progressive neurometabolic condition. \nSources: Expert list",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:21:34.629491+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.550",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CAD as ready",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:21:34.618081+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.550",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cad has been classified as Green List (High Evidence).",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:21:25.750943+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.550",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CAD as Green List (high evidence)",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:21:25.740306+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.550",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cad has been classified as Green List (High Evidence).",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:21:05.227721+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.549",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: CAD was added\ngene: CAD was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: CAD was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: CAD were set to 28007989; 25678555\nPhenotypes for gene: CAD were set to Epileptic encephalopathy, early infantile, 50, MIM#\t616457\nReview for gene: CAD was set to GREEN\nAdded comment: Five individuals from four unrelated families reported, seizures are a prominent part of the phenotype of this progressive neurometabolic condition. \nSources: Expert list",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:19:37.121904+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.63",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CAD as ready",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:19:37.110449+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.63",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cad has been classified as Green List (High Evidence).",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:19:32.232382+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.63",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CAD as Green List (high evidence)",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:19:32.219719+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.63",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cad has been classified as Green List (High Evidence).",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:18:56.098281+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.62",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: CAD was added\ngene: CAD was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: CAD was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: CAD were set to 28007989; 25678555\nPhenotypes for gene: CAD were set to Epileptic encephalopathy, early infantile, 50, MIM#\t616457\nReview for gene: CAD was set to GREEN\nAdded comment: Five individuals from four unrelated families reported, seizures are a prominent part of the phenotype of this progressive neurometabolic condition. \nSources: Expert list",
"entity_name": "CAD",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:14:58.248766+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.548",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PARS2 as ready",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:14:58.236271+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.548",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pars2 has been classified as Green List (High Evidence).",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:14:50.283096+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.548",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PARS2 were changed from to Epileptic encephalopathy, early infantile, 75, MIM# 618437",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:14:27.509001+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.547",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PARS2 were set to ",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:14:04.705508+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.546",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PARS2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:13:34.993086+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.545",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PARS2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29410512, 28077841, 25629079, 29915213; Phenotypes: Epileptic encephalopathy, early infantile, 75, MIM# 618437; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:12:41.228302+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.31",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PARS2 as ready",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:12:41.216598+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.31",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pars2 has been classified as Green List (High Evidence).",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:12:37.947552+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.31",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PARS2 were changed from to Epileptic encephalopathy, early infantile, 75, MIM# 618437",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:12:10.522429+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.30",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PARS2 were set to ",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:11:38.059943+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.29",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PARS2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:11:02.346117+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.28",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PARS2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29410512, 28077841, 25629079, 29915213; Phenotypes: Epileptic encephalopathy, early infantile, 75, MIM# 618437; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:09:38.250710+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.61",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PARS2 as ready",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:09:38.238223+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.61",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pars2 has been classified as Green List (High Evidence).",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:09:26.806153+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.61",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PARS2 as Green List (high evidence)",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:09:26.795282+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.61",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pars2 has been classified as Green List (High Evidence).",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-03T10:08:38.326306+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.60",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: PARS2 was added\ngene: PARS2 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: PARS2 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: PARS2 were set to 29410512; 28077841; 25629079; 29915213\nPhenotypes for gene: PARS2 were set to Epileptic encephalopathy, early infantile, 75, MIM#\t618437\nReview for gene: PARS2 was set to GREEN\nAdded comment: Eight individuals from four unrelated families reported; seizures are a prominent part of the phenotype. \nSources: Expert list",
"entity_name": "PARS2",
"entity_type": "gene"
},
{
"created": "2020-01-02T22:14:32.065211+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.545",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CHRNA3 as ready",
"entity_name": "CHRNA3",
"entity_type": "gene"
},
{
"created": "2020-01-02T22:14:32.053709+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.545",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: chrna3 has been classified as Green List (High Evidence).",
"entity_name": "CHRNA3",
"entity_type": "gene"
},
{
"created": "2020-01-02T22:14:23.445091+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.545",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CHRNA3 were changed from to CAKUT; dysautonomia",
"entity_name": "CHRNA3",
"entity_type": "gene"
},
{
"created": "2020-01-02T22:13:15.215092+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.544",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CHRNA3 were set to ",
"entity_name": "CHRNA3",
"entity_type": "gene"
},
{
"created": "2020-01-02T22:12:48.271251+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.543",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CHRNA3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CHRNA3",
"entity_type": "gene"
},
{
"created": "2020-01-02T22:12:29.433709+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.542",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CHRNA3: Rating: GREEN; Mode of pathogenicity: None; Publications: 31708116; Phenotypes: CAKUT, dysautonomia; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CHRNA3",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:05:00.178954+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.542",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NADSYN1 as ready",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:05:00.161316+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.542",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nadsyn1 has been classified as Green List (High Evidence).",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:04:49.844100+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.542",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NADSYN1 as Green List (high evidence)",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:04:49.831459+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.542",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nadsyn1 has been classified as Green List (High Evidence).",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:04:30.428350+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.541",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NADSYN1 was added\ngene: NADSYN1 was added to Mendeliome_VCGS. Sources: Literature\nMode of inheritance for gene: NADSYN1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NADSYN1 were set to 31883644\nPhenotypes for gene: NADSYN1 were set to Multiple congenital abnormalities; absent kidneys; cardiac; limb; vertebral\nReview for gene: NADSYN1 was set to GREEN\nAdded comment: Five individuals from four unrelated families. \nSources: Literature",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:02:21.691829+11:00",
"panel_name": "Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS",
"panel_id": 63,
"panel_version": "0.32",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NADSYN1 as ready",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:02:21.680256+11:00",
"panel_name": "Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS",
"panel_id": 63,
"panel_version": "0.32",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nadsyn1 has been classified as Green List (High Evidence).",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:02:15.662506+11:00",
"panel_name": "Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS",
"panel_id": 63,
"panel_version": "0.32",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NADSYN1 as Green List (high evidence)",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:02:15.651170+11:00",
"panel_name": "Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS",
"panel_id": 63,
"panel_version": "0.32",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nadsyn1 has been classified as Green List (High Evidence).",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T21:01:13.330238+11:00",
"panel_name": "Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS",
"panel_id": 63,
"panel_version": "0.31",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NADSYN1 was added\ngene: NADSYN1 was added to Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS. Sources: Literature\nMode of inheritance for gene: NADSYN1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NADSYN1 were set to 31883644\nPhenotypes for gene: NADSYN1 were set to Multiple congenital abnormalities; absent kidneys; cardiac; limb; vertebral\nReview for gene: NADSYN1 was set to GREEN\nAdded comment: Five individuals from four unrelated families. \nSources: Literature",
"entity_name": "NADSYN1",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:52:56.342319+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.540",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PPP1R12A as ready",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:52:56.337254+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.540",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Now published, 12 individuals, upgraded to Green.",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:52:56.310731+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.540",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ppp1r12a has been classified as Green List (High Evidence).",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:52:47.543743+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.540",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PPP1R12A were changed from to Intellectual disability; holoprosencephaly; disorder of sex development",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:52:10.254981+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.539",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PPP1R12A were set to ",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:51:28.171555+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.538",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PPP1R12A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:50:34.023903+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1462",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PPP1R12A as ready",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:50:34.018124+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1462",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Now published, 12 individuals, upgraded to Green.",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:50:33.989809+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1462",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ppp1r12a has been classified as Green List (High Evidence).",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:50:19.223161+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1462",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PPP1R12A were set to ",
"entity_name": "PPP1R12A",
"entity_type": "gene"
}
]
}