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{
"count": 220725,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2013",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2011",
"results": [
{
"created": "2020-01-02T20:50:07.395192+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1461",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PPP1R12A as Green List (high evidence)",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:50:07.383688+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ_VCGS",
"panel_id": 250,
"panel_version": "0.1461",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ppp1r12a has been classified as Green List (High Evidence).",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:49:40.213671+11:00",
"panel_name": "Holoprosencephaly and septo-optic dysplasia_VCGS",
"panel_id": 112,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PPP1R12A as ready",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:49:40.201731+11:00",
"panel_name": "Holoprosencephaly and septo-optic dysplasia_VCGS",
"panel_id": 112,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ppp1r12a has been classified as Green List (High Evidence).",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:49:36.589047+11:00",
"panel_name": "Holoprosencephaly and septo-optic dysplasia_VCGS",
"panel_id": 112,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PPP1R12A were set to ",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:49:04.086746+11:00",
"panel_name": "Holoprosencephaly and septo-optic dysplasia_VCGS",
"panel_id": 112,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PPP1R12A as Green List (high evidence)",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:49:04.075921+11:00",
"panel_name": "Holoprosencephaly and septo-optic dysplasia_VCGS",
"panel_id": 112,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ppp1r12a has been classified as Green List (High Evidence).",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:48:18.912037+11:00",
"panel_name": "Disorders of Sex Differentiation_VCGS",
"panel_id": 99,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PPP1R12A as ready",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:48:18.907047+11:00",
"panel_name": "Disorders of Sex Differentiation_VCGS",
"panel_id": 99,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Now published; 12 individuals, upgraded to Green.",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:48:18.879936+11:00",
"panel_name": "Disorders of Sex Differentiation_VCGS",
"panel_id": 99,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ppp1r12a has been classified as Green List (High Evidence).",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:47:50.415644+11:00",
"panel_name": "Disorders of Sex Differentiation_VCGS",
"panel_id": 99,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PPP1R12A as Green List (high evidence)",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:47:50.403348+11:00",
"panel_name": "Disorders of Sex Differentiation_VCGS",
"panel_id": 99,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ppp1r12a has been classified as Green List (High Evidence).",
"entity_name": "PPP1R12A",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:46:37.999492+11:00",
"panel_name": "Hypertrophic cardiomyopathy_VCGS",
"panel_id": 111,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: UQCRFS1 as ready",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:46:37.988796+11:00",
"panel_name": "Hypertrophic cardiomyopathy_VCGS",
"panel_id": 111,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: uqcrfs1 has been classified as Green List (High Evidence).",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:46:15.198061+11:00",
"panel_name": "Hypertrophic cardiomyopathy_VCGS",
"panel_id": 111,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: UQCRFS1 as Green List (high evidence)",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:46:15.186236+11:00",
"panel_name": "Hypertrophic cardiomyopathy_VCGS",
"panel_id": 111,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: uqcrfs1 has been classified as Green List (High Evidence).",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T20:45:39.243376+11:00",
"panel_name": "Hypertrophic cardiomyopathy_VCGS",
"panel_id": 111,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: UQCRFS1 was added\ngene: UQCRFS1 was added to Hypertrophic cardiomyopathy_VCGS. Sources: Literature\nMode of inheritance for gene: UQCRFS1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: UQCRFS1 were set to 31883641\nPhenotypes for gene: UQCRFS1 were set to Mitochondrial Complex III deficiency; lactic acidosis; fetal bradycardia; hypertrophic cardiomyopathy; alopecia totalis\nReview for gene: UQCRFS1 was set to GREEN\nAdded comment: Two unrelated families reported plus functional evidence. \nSources: Literature",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:56:40.737505+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.537",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: UQCRFS1 as ready",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:56:40.725181+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.537",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: uqcrfs1 has been classified as Green List (High Evidence).",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:56:33.300278+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.537",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: UQCRFS1 as Green List (high evidence)",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:56:33.289400+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.537",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: uqcrfs1 has been classified as Green List (High Evidence).",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:56:14.433857+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.536",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: UQCRFS1 was added\ngene: UQCRFS1 was added to Mendeliome_VCGS. Sources: Literature\nMode of inheritance for gene: UQCRFS1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: UQCRFS1 were set to 31883641\nPhenotypes for gene: UQCRFS1 were set to Mitochondrial Complex III deficiency; lactic acidosis; fetal bradycardia; hypertrophic cardiomyopathy; alopecia totalis\nReview for gene: UQCRFS1 was set to GREEN\nAdded comment: Two unrelated families reported plus functional evidence. \nSources: Literature",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:54:04.038858+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.28",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: UQCRFS1 as ready",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:54:04.027695+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.28",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: uqcrfs1 has been classified as Green List (High Evidence).",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:53:56.475920+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.28",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: UQCRFS1 as Green List (high evidence)",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:53:56.464334+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.28",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: uqcrfs1 has been classified as Green List (High Evidence).",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T18:53:21.001644+11:00",
"panel_name": "Mitochondrial_AustralianGenomics_VCGS",
"panel_id": 203,
"panel_version": "0.27",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: UQCRFS1 was added\ngene: UQCRFS1 was added to Mitochondrial_AustralianGenomics_VCGS. Sources: Literature\nMode of inheritance for gene: UQCRFS1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: UQCRFS1 were set to 31883641\nPhenotypes for gene: UQCRFS1 were set to Mitochondrial Complex III deficiency; lactic acidosis; fetal bradycardia; hypertrophic cardiomyopathy; alopecia totalis\nReview for gene: UQCRFS1 was set to GREEN\nAdded comment: Two unrelated families reported plus functional evidence. \nSources: Literature",
"entity_name": "UQCRFS1",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:58:19.719193+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.222",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TSPEAR as ready",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:58:19.707540+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.222",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tspear has been classified as Red List (Low Evidence).",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:58:16.340170+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.222",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TSPEAR were changed from Deafness, autosomal recessive 98, MIM#614861 to Deafness, autosomal recessive 98, MIM#614861",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:57:54.674984+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.221",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TSPEAR were changed from to Deafness, autosomal recessive 98, MIM#614861",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:57:31.735457+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.220",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TSPEAR were set to ",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:57:07.519550+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.220",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TSPEAR was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:56:38.358886+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.219",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TSPEAR as Red List (low evidence)",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:56:38.346706+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.219",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tspear has been classified as Red List (Low Evidence).",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:56:04.970641+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.218",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TSPEAR: Rating: RED; Mode of pathogenicity: None; Publications: 22678063, 26969326; Phenotypes: Deafness, autosomal recessive 98, MIM#614861; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TSPEAR",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:49:03.589196+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.218",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TNC as ready",
"entity_name": "TNC",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:49:03.578006+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.218",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tnc has been classified as Amber List (Moderate Evidence).",
"entity_name": "TNC",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:48:56.931458+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.218",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TNC were changed from to Deafness, autosomal dominant 56, MIM# 615629",
"entity_name": "TNC",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:48:33.398951+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.217",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TNC were set to ",
"entity_name": "TNC",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:48:00.572252+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.216",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TNC was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TNC",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:47:29.747612+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.215",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TNC as Amber List (moderate evidence)",
"entity_name": "TNC",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:47:29.735844+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.215",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tnc has been classified as Amber List (Moderate Evidence).",
"entity_name": "TNC",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:46:55.285725+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.214",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TNC: Rating: AMBER; Mode of pathogenicity: None; Publications: 23936043; Phenotypes: Deafness, autosomal dominant 56, MIM# 615629; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TNC",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:42:26.636880+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.214",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TJP2 as ready",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:42:26.624238+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.214",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tjp2 has been classified as Red List (Low Evidence).",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:36:56.342102+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.214",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TJP2 were changed from Deafness to Deafness",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:36:34.499882+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.214",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TJP2 were set to 24752540; 20602916; 18616530",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:35:56.761473+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.213",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TJP2 were changed from to Deafness",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:35:21.199747+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.213",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TJP2 were set to ",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:34:51.527437+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.213",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TJP2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:34:14.653136+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.212",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TJP2 as Red List (low evidence)",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:34:14.638943+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.212",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tjp2 has been classified as Red List (Low Evidence).",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:33:40.361263+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.211",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TJP2: Rating: RED; Mode of pathogenicity: None; Publications: 24752540, 20602916, 18616530; Phenotypes: Deafness; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TJP2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:25:34.181208+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.211",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SLC26A5 as ready",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:25:34.175071+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.211",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Another publication identified, plus another individual with bi-allelic variants reported by a diagnostic laboratory.",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:25:34.143923+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.211",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: slc26a5 has been classified as Green List (High Evidence).",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:25:07.577248+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.211",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Deleted their comment",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:25:03.831542+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.211",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment on publications: Another another individual with bi-allelic variants reported by a diagnostic laboratory.",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:25:03.808420+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.211",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: SLC26A5 were set to 24164807; 26969326",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:24:39.941857+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.210",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment on publications: Another another individual with bi-allelic variants reported by a diagnostic laboratory.",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:24:39.917853+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.210",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: SLC26A5 were set to 24164807",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:23:46.711003+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.209",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: SLC26A5 as Green List (high evidence)",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:23:46.691668+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.209",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: slc26a5 has been classified as Green List (High Evidence).",
"entity_name": "SLC26A5",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:05:23.245139+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.208",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MPZL2 as ready",
"entity_name": "MPZL2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:05:23.228787+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.208",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mpzl2 has been classified as Green List (High Evidence).",
"entity_name": "MPZL2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:05:16.850255+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.208",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: MPZL2 were set to ",
"entity_name": "MPZL2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:04:50.687022+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.207",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MPZL2 were changed from to Deafness, autosomal recessive 111, MIM#618145",
"entity_name": "MPZL2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:04:26.707756+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.206",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: MPZL2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "MPZL2",
"entity_type": "gene"
},
{
"created": "2020-01-02T16:03:37.194816+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.205",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MPZL2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29982980, 29961571; Phenotypes: Deafness, autosomal recessive 111, MIM#618145; Mode of inheritance: None",
"entity_name": "MPZL2",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:59:39.669327+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.205",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: LMX1A as ready",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:59:39.663441+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.205",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Two families with mono-allelic variants and dominant pattern of deafness, one family with bi-allelic variants. Mouse model.",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:59:39.635013+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.205",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lmx1a has been classified as Amber List (Moderate Evidence).",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:59:37.148264+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.205",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: LMX1A were changed from to Deafness, autosomal recessive and autosomal dominant",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:59:13.521819+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.204",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: LMX1A were set to ",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:57:48.418522+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.203",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: LMX1A was changed from BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:57:21.190933+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.202",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: LMX1A as Amber List (moderate evidence)",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:57:21.179921+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.202",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lmx1a has been classified as Amber List (Moderate Evidence).",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:56:58.727261+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.201",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: LMX1A was changed from Unknown to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:56:35.422258+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.201",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: LMX1A as Amber List (moderate evidence)",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:56:35.355884+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.201",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lmx1a has been classified as Amber List (Moderate Evidence).",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:54:40.368198+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.200",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: LMX1A: Rating: AMBER; Mode of pathogenicity: None; Publications: 29971487; Phenotypes: Deafness, autosomal recessive; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "LMX1A",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:49:48.238748+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.200",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HGF as ready",
"entity_name": "HGF",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:49:48.233451+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.200",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: Note founder variants are synonymous (S165S) or deep intronic, c.482+1986_1988, c.482+1991_2000del",
"entity_name": "HGF",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:49:48.205792+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.200",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hgf has been classified as Green List (High Evidence).",
"entity_name": "HGF",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:49:07.420175+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.200",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HGF were set to ",
"entity_name": "HGF",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:37:22.881000+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.199",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GJB6 as Red List (low evidence)",
"entity_name": "GJB6",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:37:22.862004+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.199",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gjb6 has been classified as Red List (Low Evidence).",
"entity_name": "GJB6",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:37:07.786677+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.198",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GJB6 as ready",
"entity_name": "GJB6",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:37:07.773506+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.198",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gjb6 has been classified as Red List (Low Evidence).",
"entity_name": "GJB6",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:36:58.416984+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.198",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: GJB6 were changed from to Deafness, autosomal recessive and autosomal dominant",
"entity_name": "GJB6",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:36:33.982609+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.198",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GJB6 as Red List (low evidence)",
"entity_name": "GJB6",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:36:33.918435+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.198",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gjb6 has been classified as Red List (Low Evidence).",
"entity_name": "GJB6",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:35:59.924532+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.197",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: GJB6: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Deafness, autosomal recessive and autosomal dominant; Mode of inheritance: None",
"entity_name": "GJB6",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:30:18.267561+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.197",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GJB4 as ready",
"entity_name": "GJB4",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:30:18.256347+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.197",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gjb4 has been classified as Red List (Low Evidence).",
"entity_name": "GJB4",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:30:14.052628+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.197",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: GJB4 as Red List (low evidence)",
"entity_name": "GJB4",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:30:14.041311+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.197",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: gjb4 has been classified as Red List (Low Evidence).",
"entity_name": "GJB4",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:29:40.533686+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.196",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: GJB4: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: Unknown",
"entity_name": "GJB4",
"entity_type": "gene"
},
{
"created": "2020-01-02T15:23:34.511870+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.196",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GJB1 as ready",
"entity_name": "GJB1",
"entity_type": "gene"
}
]
}