HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 220725,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2019",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2017",
"results": [
{
"created": "2019-12-31T13:25:01.561794+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.90",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lars2 has been classified as Green List (High Evidence).",
"entity_name": "LARS2",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:24:58.938132+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.90",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: LARS2 were changed from to Perrault syndrome 4, MIM#615300",
"entity_name": "LARS2",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:24:05.393183+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.89",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: LARS2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "LARS2",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:22:56.077333+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.473",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KITLG as ready",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:22:56.061397+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.473",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kitlg has been classified as Amber List (Moderate Evidence).",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:22:47.897453+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.473",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: KITLG was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:22:21.371802+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.472",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: KITLG were set to ",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:15:24.338770+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.471",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: KITLG were changed from to Deafness, autosomal dominant 69, unilateral or asymmetric, MIM# 616697",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:14:58.249885+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.470",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: KITLG as Amber List (moderate evidence)",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:14:58.237080+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.470",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kitlg has been classified as Amber List (Moderate Evidence).",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:14:40.646014+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.469",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: KITLG: Rating: AMBER; Mode of pathogenicity: None; Publications: 26522471; Phenotypes: Deafness, autosomal dominant 69, unilateral or asymmetric, MIM# 616697; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:12:40.308011+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MCM2 as ready",
"entity_name": "MCM2",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:12:40.296451+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mcm2 has been classified as Red List (Low Evidence).",
"entity_name": "MCM2",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:12:36.499882+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: MCM2 as Red List (low evidence)",
"entity_name": "MCM2",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:12:36.484862+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.88",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mcm2 has been classified as Red List (Low Evidence).",
"entity_name": "MCM2",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:11:26.260021+11:00",
"panel_name": "Autism_VCGS",
"panel_id": 51,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MET as ready",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:11:26.247897+11:00",
"panel_name": "Autism_VCGS",
"panel_id": 51,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: met has been classified as Red List (Low Evidence).",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:11:03.001122+11:00",
"panel_name": "Autism_VCGS",
"panel_id": 51,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MET were changed from to ?Deafness, autosomal recessive 97, OMIM #616705; {Osteofibrous dysplasia, susceptibility to}, OMIM #607278",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:10:40.154298+11:00",
"panel_name": "Autism_VCGS",
"panel_id": 51,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: MET was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:10:18.512442+11:00",
"panel_name": "Autism_VCGS",
"panel_id": 51,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: MET as Red List (low evidence)",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:10:18.447657+11:00",
"panel_name": "Autism_VCGS",
"panel_id": 51,
"panel_version": "0.19",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: met has been classified as Red List (Low Evidence).",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:07:24.305694+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.87",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MIR96 as ready",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:07:24.294719+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.87",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mir96 has been classified as Amber List (Moderate Evidence).",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:07:11.794035+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.87",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MIR96 were changed from Autosomal dominant hearing loss to Deafness, autosomal dominant 50, MIM# 613074",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:06:36.328943+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.469",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MIR96 were changed from to Deafness, autosomal dominant 50, MIM# 613074",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:06:23.719795+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.468",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: MIR96 were set to ",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:06:10.498500+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.467",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: MIR96 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:05:53.670553+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.466",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: MIR96 as Amber List (moderate evidence)",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:05:53.658393+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.466",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mir96 has been classified as Amber List (Moderate Evidence).",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:05:35.735588+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.465",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MIR96: Rating: AMBER; Mode of pathogenicity: None; Publications: 19363479, 29325119; Phenotypes: Deafness, autosomal dominant 50, MIM# 613074; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:03:36.531839+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.86",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MIR96 as ready",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:03:36.519833+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.86",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mir96 has been classified as Amber List (Moderate Evidence).",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:02:44.694914+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.86",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MIR96 were changed from to Autosomal dominant hearing loss",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:02:02.701198+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.85",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: MIR96 were set to ",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T13:01:42.438572+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.85",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: MIR96 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:59:29.709248+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: MIR96 as Amber List (moderate evidence)",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:59:29.696971+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.84",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: mir96 has been classified as Amber List (Moderate Evidence).",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:50:25.322592+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MYO3A: Rating: GREEN; Mode of pathogenicity: None; Publications: 21165622, 26754646, 23990876; Phenotypes: Deafness, autosomal recessive 30, MIM# 607101; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "MYO3A",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:46:57.678091+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MYH14 as ready",
"entity_name": "MYH14",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:46:57.667064+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: myh14 has been classified as Green List (High Evidence).",
"entity_name": "MYH14",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:46:52.490766+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MYH14 were changed from Deafness, autosomal dominant 4A, MIM# 600652 to Deafness, autosomal dominant 4A, MIM# 600652",
"entity_name": "MYH14",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:46:32.422628+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MYH14 were changed from to Deafness, autosomal dominant 4A, MIM# 600652",
"entity_name": "MYH14",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:46:11.621620+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: MYH14 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MYH14",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:45:36.437308+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.81",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MYH14: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Deafness, autosomal dominant 4A, MIM# 600652; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MYH14",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:45:07.390237+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.81",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "reviewed gene: MIR96: Rating: AMBER; Mode of pathogenicity: None; Publications: 19363479, 29325119; Phenotypes: Autosomal dominant hearing loss; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "MIR96",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:44:04.114060+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.81",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MSRB3 as ready",
"entity_name": "MSRB3",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:44:04.103044+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.81",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: msrb3 has been classified as Green List (High Evidence).",
"entity_name": "MSRB3",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:44:00.534077+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.81",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: MSRB3 were changed from to Deafness, autosomal recessive 74, MIM# 613718",
"entity_name": "MSRB3",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:43:37.786268+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.80",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: MSRB3 were set to ",
"entity_name": "MSRB3",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:43:02.279216+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: MSRB3: Rating: ; Mode of pathogenicity: None; Publications: 19650862, 24191262, 21185009; Phenotypes: Deafness, autosomal recessive 74, MIM# 613718; Mode of inheritance: None",
"entity_name": "MSRB3",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:39:50.291918+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: MET as ready",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:39:50.278355+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: met has been classified as Red List (Low Evidence).",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:39:24.090419+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: MET was added\ngene: MET was added to Deafness_MelbourneGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: MET was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: MET were set to 25941349; 31801140\nPhenotypes for gene: MET were set to Deafness, autosomal recessive 97, MIM#\t616705\nReview for gene: MET was set to RED\nAdded comment: Two families reported, no functional data. \nSources: Expert list",
"entity_name": "MET",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:37:51.836501+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.78",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "gene: MCM2 was added\ngene: MCM2 was added to Deafness_MelbourneGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: MCM2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: MCM2 were set to 26196677\nPhenotypes for gene: MCM2 were set to Autosomal dominant hearing loss\nReview for gene: MCM2 was set to RED\nAdded comment: One family, expression studies. \nSources: Expert list",
"entity_name": "MCM2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:34:22.753598+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KITLG as ready",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:34:22.741501+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kitlg has been classified as Amber List (Moderate Evidence).",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:34:18.866060+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: KITLG as Amber List (moderate evidence)",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:34:18.854312+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kitlg has been classified as Amber List (Moderate Evidence).",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:34:10.558331+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.77",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "reviewed gene: LARS2: Rating: GREEN; Mode of pathogenicity: None; Publications: 23541342, 27650058, 26970254, 26657938, 28832386, 28000701, 29205794; Phenotypes: Perrault syndrome; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "LARS2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:33:49.006086+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.77",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: KITLG was added\ngene: KITLG was added to Deafness_MelbourneGenomics_VCGS. Sources: Expert list\nMode of inheritance for gene: KITLG was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: KITLG were set to 26522471\nPhenotypes for gene: KITLG were set to Deafness, autosomal dominant 69, unilateral or asymmetric, MIM#\t616697\nReview for gene: KITLG was set to AMBER\nAdded comment: Two unrelated families, limited functional data. \nSources: Expert list",
"entity_name": "KITLG",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:30:40.674580+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.76",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "reviewed gene: KCNJ10: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "KCNJ10",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:29:20.212902+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KCNE1 as ready",
"entity_name": "KCNE1",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:29:20.200393+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kcne1 has been classified as Green List (High Evidence).",
"entity_name": "KCNE1",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:29:16.355329+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: KCNE1 were changed from Jervell and Lange-Nielsen syndrome 2, MIM# 612347 to Jervell and Lange-Nielsen syndrome 2, MIM# 612347",
"entity_name": "KCNE1",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:28:54.746210+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: KCNE1 were changed from to Jervell and Lange-Nielsen syndrome 2, MIM# 612347",
"entity_name": "KCNE1",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:28:31.252677+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.75",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: KCNE1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "KCNE1",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:27:44.190083+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: KCNE1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Jervell and Lange-Nielsen syndrome 2, MIM# 612347; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "KCNE1",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:26:43.800134+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.74",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "reviewed gene: KARS: Rating: GREEN; Mode of pathogenicity: None; Publications: 23768514, 23768514, 14975237; Phenotypes: autosomal recessive sensorineural hearing loss; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "KARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:26:00.904620+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HOMER2 as ready",
"entity_name": "HOMER2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:26:00.893130+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: homer2 has been classified as Green List (High Evidence).",
"entity_name": "HOMER2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:25:56.998787+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HOMER2 were changed from to Deafness, autosomal dominant 68, MIM# 616707",
"entity_name": "HOMER2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:25:34.166883+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HOMER2 were set to ",
"entity_name": "HOMER2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:24:58.024081+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: HOMER2: Rating: ; Mode of pathogenicity: None; Publications: 25816005, 30047143, 25816005; Phenotypes: Deafness, autosomal dominant 68, MIM# 616707; Mode of inheritance: None",
"entity_name": "HOMER2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:21:40.415992+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.72",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "reviewed gene: HARS2: Rating: GREEN; Mode of pathogenicity: None; Publications: 21464306, 27650058, 31827252, 31486067; Phenotypes: Perrault syndrome, autosomal recessive sensorineural hearing loss; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HARS2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:21:11.348480+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HGF as ready",
"entity_name": "HGF",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:21:11.335988+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hgf has been classified as Green List (High Evidence).",
"entity_name": "HGF",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:21:08.604237+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HGF were changed from to Deafness, autosomal recessive 39, MIM# 608265",
"entity_name": "HGF",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:20:36.330299+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.71",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: HGF: Rating: GREEN; Mode of pathogenicity: None; Publications: 19576567; Phenotypes: Deafness, autosomal recessive 39, MIM# 608265; Mode of inheritance: None",
"entity_name": "HGF",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:17:11.386755+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.71",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HARS were set to 22279524",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:17:03.775139+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.70",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HARS as ready",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:17:03.762393+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.70",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hars has been classified as Red List (Low Evidence).",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:16:25.925973+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.70",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HARS were changed from Usher syndrome type 3B, MIM# 614504 to Usher syndrome type 3B, MIM# 614504",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:16:05.395111+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HARS was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:15:44.999219+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HARS were changed from to Usher syndrome type 3B, MIM# 614504",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:15:25.888833+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.68",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "changed review comment from: Single family with multiple sibs, function studies.; to: Single family with multiple sibs, function studies. 'Moderate' classification from ClinGen expert panel.",
"entity_name": "GRXCR2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:15:21.902488+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HARS were set to ",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:14:57.844010+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: HARS as Red List (low evidence)",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:14:57.799362+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.68",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hars has been classified as Red List (Low Evidence).",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:14:36.948888+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.67",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "reviewed gene: GRXCR2: Rating: AMBER; Mode of pathogenicity: None; Publications: 24619944; Phenotypes: autosomal recessive sensorineural hearing loss; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "GRXCR2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:14:25.570272+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: HARS: Rating: RED; Mode of pathogenicity: None; Publications: 22279524; Phenotypes: Usher syndrome type 3B, MIM# 614504; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HARS",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:10:11.104461+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GRHL2 as ready",
"entity_name": "GRHL2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:10:11.093387+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: grhl2 has been classified as Green List (High Evidence).",
"entity_name": "GRHL2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:10:08.420746+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.67",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: GRHL2 were changed from Deafness, autosomal dominant 28, MIM# 608641 to Deafness, autosomal dominant 28, MIM# 608641",
"entity_name": "GRHL2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:09:44.694365+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.66",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: GRHL2 was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GRHL2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:09:08.211408+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.65",
"user_name": "Lilian Rudd",
"item_type": "entity",
"text": "reviewed gene: FOXI1: Rating: GREEN; Mode of pathogenicity: None; Publications: 29242249, 9843211; Phenotypes: sensorineural deafness and distal renal tubular acidosis; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "FOXI1",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:09:05.360186+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: GRHL2 were changed from to Deafness, autosomal dominant 28, MIM# 608641",
"entity_name": "GRHL2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:08:42.483347+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: GRHL2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GRHL2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:08:11.899718+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: GRHL2: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Deafness, autosomal dominant 28, MIM# 608641; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "GRHL2",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:06:26.355131+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: GJB3 were changed from Deafness, autosomal dominant 2B, MIM# 612644 to Deafness, autosomal dominant 2B, MIM# 612644",
"entity_name": "GJB3",
"entity_type": "gene"
},
{
"created": "2019-12-31T12:06:10.668036+11:00",
"panel_name": "Deafness_MelbourneGenomics_VCGS",
"panel_id": 209,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: GJB3 as ready",
"entity_name": "GJB3",
"entity_type": "gene"
}
]
}