HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 220504,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2031",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2029",
"results": [
{
"created": "2019-12-20T15:52:08.325163+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cfh has been classified as Green List (High Evidence).",
"entity_name": "CFH",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:52:04.991643+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CFH were changed from to Complement factor H deficiency, MIM#609814",
"entity_name": "CFH",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:51:42.446810+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CFH was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "CFH",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:51:02.470070+11:00",
"panel_name": "Haematuria_VCGS_KidGen",
"panel_id": 39,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CFH: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Complement factor H deficiency, MIM#609814; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "CFH",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:46:48.469061+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.388",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP37 was added\ngene: NUP37 was added to Mendeliome_VCGS. Sources: Literature\nMode of inheritance for gene: NUP37 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP37 were set to 30179222\nPhenotypes for gene: NUP37 were set to Nephrotic syndrome\nReview for gene: NUP37 was set to RED\nAdded comment: Single family reported with nephrotic syndrome. \nSources: Literature",
"entity_name": "NUP37",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:45:02.139068+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.54",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP37 as ready",
"entity_name": "NUP37",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:45:02.127363+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.54",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup37 has been classified as Red List (Low Evidence).",
"entity_name": "NUP37",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:44:51.532777+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.54",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP37 was added\ngene: NUP37 was added to Proteinuria_VCGS_KidGen. Sources: Expert list\nMode of inheritance for gene: NUP37 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP37 were set to 30179222\nPhenotypes for gene: NUP37 were set to Nephrotic syndrome\nReview for gene: NUP37 was set to RED\nAdded comment: Single family reported. \nSources: Expert list",
"entity_name": "NUP37",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:40:09.429421+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.387",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP133 as ready",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:40:09.422434+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.387",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup133 has been classified as Green List (High Evidence).",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:39:59.994672+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.387",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NUP133 as Green List (high evidence)",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:39:59.987457+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.387",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup133 has been classified as Green List (High Evidence).",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:39:39.656331+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.386",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP133 was added\ngene: NUP133 was added to Mendeliome_VCGS. Sources: Literature\nMode of inheritance for gene: NUP133 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP133 were set to 30179222\nPhenotypes for gene: NUP133 were set to Nephrotic syndrome, type 18, MIM#618177\nReview for gene: NUP133 was set to GREEN\nAdded comment: Two unrelated families with functional data. \nSources: Literature",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:37:52.509289+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.385",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP160 as ready",
"entity_name": "NUP160",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:37:52.502478+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.385",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup160 has been classified as Red List (Low Evidence).",
"entity_name": "NUP160",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:37:40.358665+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.385",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP160 was added\ngene: NUP160 was added to Mendeliome_VCGS. Sources: Literature\nMode of inheritance for gene: NUP160 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP160 were set to 30179222\nPhenotypes for gene: NUP160 were set to Nephrotic syndrome, type 19, MIM#618178\nReview for gene: NUP160 was set to RED\nAdded comment: Single family, no functional data. \nSources: Literature",
"entity_name": "NUP160",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:35:28.639411+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP160 as ready",
"entity_name": "NUP160",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:35:28.632529+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup160 has been classified as Red List (Low Evidence).",
"entity_name": "NUP160",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:35:18.848758+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.53",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP160 was added\ngene: NUP160 was added to Proteinuria_VCGS_KidGen. Sources: Literature\nMode of inheritance for gene: NUP160 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP160 were set to 30179222\nPhenotypes for gene: NUP160 were set to Nephrotic syndrome, type 19, MIM#618178\nReview for gene: NUP160 was set to RED\nAdded comment: Single family, no functional data. \nSources: Literature",
"entity_name": "NUP160",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:33:02.034071+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.52",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP133 as ready",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:33:02.006756+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.52",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup133 has been classified as Green List (High Evidence).",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:27:47.502029+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.52",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NUP133 as Green List (high evidence)",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:27:47.495307+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.52",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup133 has been classified as Green List (High Evidence).",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:27:20.518057+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.51",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP133 was added\ngene: NUP133 was added to Proteinuria_VCGS_KidGen. Sources: Literature\nMode of inheritance for gene: NUP133 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP133 were set to 30179222\nPhenotypes for gene: NUP133 were set to Nephrotic syndrome, type 18, MIM#618177\nReview for gene: NUP133 was set to GREEN\nAdded comment: Two unrelated families with functional data. \nSources: Literature",
"entity_name": "NUP133",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:24:33.237483+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.384",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP85 as ready",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:24:33.230205+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.384",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup85 has been classified as Green List (High Evidence).",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:24:22.838592+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.384",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NUP85 as Green List (high evidence)",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:24:22.831741+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.384",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup85 has been classified as Green List (High Evidence).",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:23:54.765130+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.383",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP85 was added\ngene: NUP85 was added to Mendeliome_VCGS. Sources: Literature\nMode of inheritance for gene: NUP85 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP85 were set to 30179222\nPhenotypes for gene: NUP85 were set to Nephrotic syndrome, type 17, MIM#618176\nReview for gene: NUP85 was set to GREEN\nAdded comment: Three unrelated families reported. \nSources: Literature",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:21:46.786979+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.50",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP85 as ready",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:21:46.779764+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.50",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup85 has been classified as Green List (High Evidence).",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:21:41.142078+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.50",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NUP85 as Green List (high evidence)",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:21:41.132529+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.50",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup85 has been classified as Green List (High Evidence).",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T15:21:11.446209+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.49",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP85 was added\ngene: NUP85 was added to Proteinuria_VCGS_KidGen. Sources: Literature\nMode of inheritance for gene: NUP85 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP85 were set to 30179222\nPhenotypes for gene: NUP85 were set to Nephrotic syndrome, type 17, MIM#618176\nReview for gene: NUP85 was set to GREEN\nAdded comment: Three unrelated families described. \nSources: Literature",
"entity_name": "NUP85",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:26:53.700023+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.48",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PAX2 as ready",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:26:53.692636+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.48",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pax2 has been classified as Green List (High Evidence).",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:26:50.575055+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.48",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: PAX2 were changed from to Glomerulosclerosis, focal segmental, 7, MIM#616002",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:26:27.539949+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.47",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: PAX2 were set to ",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:25:59.606621+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.46",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: PAX2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:25:30.402165+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: PAX2: Rating: GREEN; Mode of pathogenicity: None; Publications: 24676634; Phenotypes: Glomerulosclerosis, focal segmental, 7, MIM#616002; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "PAX2",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:22:43.464725+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TTC21B as ready",
"entity_name": "TTC21B",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:22:43.457852+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ttc21b has been classified as Red List (Low Evidence).",
"entity_name": "TTC21B",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:22:39.119024+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.45",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TTC21B were changed from to Nephronophthisis 12, MIM#613820",
"entity_name": "TTC21B",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:22:10.608221+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.44",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TTC21B was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TTC21B",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:21:43.782549+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.43",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TTC21B as Red List (low evidence)",
"entity_name": "TTC21B",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:21:43.775500+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.43",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ttc21b has been classified as Red List (Low Evidence).",
"entity_name": "TTC21B",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:21:15.903669+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TTC21B: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Nephronophthisis 12, MIM#613820; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TTC21B",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:19:40.350704+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.382",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: XPO5 as ready",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:19:40.343875+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.382",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: xpo5 has been classified as Amber List (Moderate Evidence).",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:17:46.840048+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.382",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: XPO5 were changed from to Nephrotic syndrome",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:17:30.452387+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.381",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: XPO5 were set to ",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:17:09.218221+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.380",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: XPO5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:16:49.272993+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.379",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: XPO5 as Amber List (moderate evidence)",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:16:49.266462+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.379",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: xpo5 has been classified as Amber List (Moderate Evidence).",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:16:28.611678+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.378",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: XPO5: Rating: AMBER; Mode of pathogenicity: None; Publications: 26878725; Phenotypes: Nephrotic syndrome; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:14:53.632486+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: XPO5 as ready",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:14:53.625540+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: xpo5 has been classified as Amber List (Moderate Evidence).",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:14:48.943078+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: XPO5 as Amber List (moderate evidence)",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:14:48.935678+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.42",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: xpo5 has been classified as Amber List (Moderate Evidence).",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:14:18.671993+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.41",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: XPO5 was added\ngene: XPO5 was added to Proteinuria_VCGS_KidGen. Sources: Expert list\nMode of inheritance for gene: XPO5 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: XPO5 were set to 26878725\nPhenotypes for gene: XPO5 were set to Nephrotic syndrome\nReview for gene: XPO5 was set to AMBER\nAdded comment: Singe family reported. \nSources: Expert list",
"entity_name": "XPO5",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:11:04.972305+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.40",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP93 as ready",
"entity_name": "NUP93",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:11:04.965331+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.40",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup93 has been classified as Green List (High Evidence).",
"entity_name": "NUP93",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:10:38.576412+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.40",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NUP93 as Green List (high evidence)",
"entity_name": "NUP93",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:10:38.568451+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.40",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup93 has been classified as Green List (High Evidence).",
"entity_name": "NUP93",
"entity_type": "gene"
},
{
"created": "2019-12-20T14:05:16.323545+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.39",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP93 was added\ngene: NUP93 was added to Proteinuria_VCGS_KidGen. Sources: Expert list\nMode of inheritance for gene: NUP93 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP93 were set to 26878725\nPhenotypes for gene: NUP93 were set to Nephrotic syndrome, type 12, MIM#616892\nReview for gene: NUP93 was set to GREEN\nAdded comment: 7 individuals from six unrelated families reported with bi-allelic variants in this gene. \nSources: Expert list",
"entity_name": "NUP93",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:59:08.790901+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.378",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP205 as ready",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:59:08.784108+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.378",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup205 has been classified as Red List (Low Evidence).",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:58:54.159884+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.378",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NUP205 were changed from to Nephrotic syndrome, type 13, MIM#616893",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:58:28.818632+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.377",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NUP205 were set to ",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:58:05.944371+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.376",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NUP205 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:57:45.577085+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.375",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NUP205 as Red List (low evidence)",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:57:45.570104+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.375",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup205 has been classified as Red List (Low Evidence).",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:51:52.952647+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.374",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: NUP205: Rating: RED; Mode of pathogenicity: None; Publications: 26878725; Phenotypes: Nephrotic syndrome, type 13, MIM#616893; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:50:30.967389+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.38",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NUP205 as ready",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:50:30.960152+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.38",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nup205 has been classified as Red List (Low Evidence).",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:50:20.697495+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.38",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: NUP205 was added\ngene: NUP205 was added to Proteinuria_VCGS_KidGen. Sources: Expert list\nMode of inheritance for gene: NUP205 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP205 were set to 26878725\nPhenotypes for gene: NUP205 were set to Nephrotic syndrome, type 13, MIM#616893\nReview for gene: NUP205 was set to RED\nAdded comment: Single family described so far. \nSources: Expert list",
"entity_name": "NUP205",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:44:33.923077+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.37",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: LMNA as ready",
"entity_name": "LMNA",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:44:33.915757+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.37",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lmna has been classified as Red List (Low Evidence).",
"entity_name": "LMNA",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:44:29.531637+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.37",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: LMNA were changed from to Familial partial lipodystrophy; FSGS",
"entity_name": "LMNA",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:44:04.254492+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.36",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: LMNA were set to ",
"entity_name": "LMNA",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:43:37.719749+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.35",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: LMNA was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "LMNA",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:43:09.187654+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.34",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: LMNA as Red List (low evidence)",
"entity_name": "LMNA",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:43:09.180604+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.34",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lmna has been classified as Red List (Low Evidence).",
"entity_name": "LMNA",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:42:41.398619+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.33",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: LMNA: Rating: RED; Mode of pathogenicity: None; Publications: 24080738; Phenotypes: Familial partial lipodystrophy, FSGS; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "LMNA",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:40:08.563752+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.374",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: KANK1 as Amber List (moderate evidence)",
"entity_name": "KANK1",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:40:08.560573+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.374",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment on list classification: Amber for nephrotic after discussion with Chirag Patel.",
"entity_name": "KANK1",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:40:08.541573+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.374",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kank1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "KANK1",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:38:51.718125+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.373",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KANK4 as ready",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:38:51.710812+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.373",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kank4 has been classified as Amber List (Moderate Evidence).",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:37:51.424114+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.373",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: KANK4 as Amber List (moderate evidence)",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:37:51.417339+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.373",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kank4 has been classified as Amber List (Moderate Evidence).",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:37:22.913580+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.372",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: KANK4 was added\ngene: KANK4 was added to Mendeliome_VCGS. Sources: Expert list\nMode of inheritance for gene: KANK4 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: KANK4 were set to 25961457\nPhenotypes for gene: KANK4 were set to Nephrotic syndrome\nReview for gene: KANK4 was set to AMBER\nAdded comment: Two individuals from a single family reported; gene belongs to a family implicated in nephrotic syndrome. \nSources: Expert list",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:34:50.265942+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.33",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: KANK4 as ready",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:34:50.256085+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.33",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kank4 has been classified as Amber List (Moderate Evidence).",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:34:44.095180+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.33",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: KANK4 as Amber List (moderate evidence)",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:34:44.088193+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.33",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: kank4 has been classified as Amber List (Moderate Evidence).",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:34:15.629350+11:00",
"panel_name": "Alternating hemiplegia including hemiplegic migraine_VCGS",
"panel_id": 40,
"panel_version": "0.0",
"user_name": "Michelle Torres",
"item_type": "entity",
"text": "reviewed gene: PRRT2: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID 22101681, PMID 22744660, PMID 31124310, PMID 26561923; Phenotypes: Convulsions, familial infantile, with paroxysmal choreoathetosis, 602066, Episodic kinesigenic dyskinesia 1, 128200, Seizures, benign familial infantile, 2, 605751; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted; Current diagnostic: yes",
"entity_name": "PRRT2",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:34:09.812699+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.32",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: KANK4 was added\ngene: KANK4 was added to Proteinuria_VCGS_KidGen. Sources: Expert list\nMode of inheritance for gene: KANK4 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: KANK4 were set to 25961457\nReview for gene: KANK4 was set to AMBER\nAdded comment: Single family with two affected individuals reported; belongs to family of proteins implicated in nephrotic syndrome. \nSources: Expert list",
"entity_name": "KANK4",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:30:42.101021+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.31",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: KANK1 as Amber List (moderate evidence)",
"entity_name": "KANK1",
"entity_type": "gene"
},
{
"created": "2019-12-20T13:30:42.097083+11:00",
"panel_name": "Proteinuria_VCGS_KidGen",
"panel_id": 144,
"panel_version": "0.31",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment on list classification: Note previously discussed with Chirag Patel, Amber for now.",
"entity_name": "KANK1",
"entity_type": "gene"
}
]
}