HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 220324,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2085",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=2083",
"results": [
{
"created": "2019-11-26T20:35:17.757890+11:00",
"panel_name": "Callosome_VCGS",
"panel_id": 205,
"panel_version": "0.8",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cd96 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:35:13.446922+11:00",
"panel_name": "Callosome_VCGS",
"panel_id": 205,
"panel_version": "0.8",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CD96 were changed from to C syndrome, MIM#211750",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:34:42.739415+11:00",
"panel_name": "Callosome_VCGS",
"panel_id": 205,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CD96 were set to ",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:34:12.311814+11:00",
"panel_name": "Callosome_VCGS",
"panel_id": 205,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CD96 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:33:45.871634+11:00",
"panel_name": "Callosome_VCGS",
"panel_id": 205,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CD96 as Amber List (moderate evidence)",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:33:45.864268+11:00",
"panel_name": "Callosome_VCGS",
"panel_id": 205,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cd96 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:32:57.178317+11:00",
"panel_name": "Polydactyly_VCGS",
"panel_id": 159,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CD96 as ready",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:32:57.171151+11:00",
"panel_name": "Polydactyly_VCGS",
"panel_id": 159,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cd96 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:32:54.126824+11:00",
"panel_name": "Polydactyly_VCGS",
"panel_id": 159,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CD96 were changed from to C syndrome, MIM#211750",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:32:22.490856+11:00",
"panel_name": "Polydactyly_VCGS",
"panel_id": 159,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CD96 were set to ",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:31:47.504224+11:00",
"panel_name": "Polydactyly_VCGS",
"panel_id": 159,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CD96 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:31:20.461861+11:00",
"panel_name": "Polydactyly_VCGS",
"panel_id": 159,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CD96 as Amber List (moderate evidence)",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:31:20.446450+11:00",
"panel_name": "Polydactyly_VCGS",
"panel_id": 159,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cd96 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T20:28:33.899963+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CD96: Rating: AMBER; Mode of pathogenicity: None; Publications: 17847009; Phenotypes: C syndrome, MIM#211750; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CD96",
"entity_type": "gene"
},
{
"created": "2019-11-26T11:06:17.326845+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.87",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: WDFY3 as ready",
"entity_name": "WDFY3",
"entity_type": "gene"
},
{
"created": "2019-11-26T11:06:17.317887+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.87",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: wdfy3 has been classified as Green List (High Evidence).",
"entity_name": "WDFY3",
"entity_type": "gene"
},
{
"created": "2019-11-26T11:06:09.417063+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.87",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: WDFY3 were changed from to Microcephaly 18, primary, autosomal dominant, MIM#617520",
"entity_name": "WDFY3",
"entity_type": "gene"
},
{
"created": "2019-11-26T11:05:45.434801+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.86",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: WDFY3 were set to ",
"entity_name": "WDFY3",
"entity_type": "gene"
},
{
"created": "2019-11-26T11:05:19.904947+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.85",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: WDFY3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "WDFY3",
"entity_type": "gene"
},
{
"created": "2019-11-26T10:33:15.473670+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SALL3 as ready",
"entity_name": "SALL3",
"entity_type": "gene"
},
{
"created": "2019-11-26T10:33:15.466714+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: sall3 has been classified as Red List (Low Evidence).",
"entity_name": "SALL3",
"entity_type": "gene"
},
{
"created": "2019-11-26T10:33:03.309604+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: SALL3 as Red List (low evidence)",
"entity_name": "SALL3",
"entity_type": "gene"
},
{
"created": "2019-11-26T10:33:03.300348+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.83",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: sall3 has been classified as Red List (Low Evidence).",
"entity_name": "SALL3",
"entity_type": "gene"
},
{
"created": "2019-11-26T10:32:25.610799+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: SALL3: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "SALL3",
"entity_type": "gene"
},
{
"created": "2019-11-25T20:14:03.659461+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CCDC8 as ready",
"entity_name": "CCDC8",
"entity_type": "gene"
},
{
"created": "2019-11-25T20:14:03.651607+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ccdc8 has been classified as Green List (High Evidence).",
"entity_name": "CCDC8",
"entity_type": "gene"
},
{
"created": "2019-11-25T20:13:55.412600+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.82",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CCDC8 were changed from to 3-M syndrome 3, MIM#614205",
"entity_name": "CCDC8",
"entity_type": "gene"
},
{
"created": "2019-11-25T20:13:30.664461+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.81",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CCDC8 were set to ",
"entity_name": "CCDC8",
"entity_type": "gene"
},
{
"created": "2019-11-25T20:13:05.282192+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.80",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CCDC8 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CCDC8",
"entity_type": "gene"
},
{
"created": "2019-11-25T20:12:42.939319+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CCDC8: Rating: GREEN; Mode of pathogenicity: None; Publications: 21737058; Phenotypes: 3-M syndrome 3, MIM#614205; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CCDC8",
"entity_type": "gene"
},
{
"created": "2019-11-25T20:10:20.654992+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CCDC8: Rating: RED; Mode of pathogenicity: None; Publications: 21737058; Phenotypes: 3-M syndrome 3, MIM#614205; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CCDC8",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:32:56.962972+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CCDC78 as ready",
"entity_name": "CCDC78",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:32:56.955850+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ccdc78 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CCDC78",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:32:48.202897+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CCDC78 were changed from to Centronuclear myopathy 4, MIM#614807",
"entity_name": "CCDC78",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:32:24.296477+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CCDC78 were set to ",
"entity_name": "CCDC78",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:32:01.501104+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.77",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CCDC78 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CCDC78",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:31:42.090348+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CCDC78 as Amber List (moderate evidence)",
"entity_name": "CCDC78",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:31:42.082805+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.76",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ccdc78 has been classified as Amber List (Moderate Evidence).",
"entity_name": "CCDC78",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:22:45.249747+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CCDC78: Rating: AMBER; Mode of pathogenicity: None; Publications: 22818856; Phenotypes: Centronuclear myopathy 4, MIM#614807; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CCDC78",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:19:40.166803+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CACNA1G as ready",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:19:40.163172+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Added comment: Comment when marking as ready: 2/4 reported patients had epilepsy.",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:19:40.138471+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cacna1g has been classified as Green List (High Evidence).",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:19:09.629140+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CACNA1G were changed from to Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits, MIM#618087",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:18:38.235166+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CACNA1G were set to ",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:18:08.587096+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CACNA1G was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:17:09.558253+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CACNA1G as ready",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:17:09.551169+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cacna1g has been classified as Green List (High Evidence).",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:16:58.230740+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.74",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CACNA1G were changed from to Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits, MIM#618087",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:16:26.920594+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CACNA1G were set to ",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T18:15:04.099839+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CACNA1G was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:30:13.125113+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CACNA1G: Rating: GREEN; Mode of pathogenicity: None; Publications: 29878067; Phenotypes: Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits, MIM#618087; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CACNA1G",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:27:35.481399+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CACNA1E as ready",
"entity_name": "CACNA1E",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:27:35.474431+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cacna1e has been classified as Green List (High Evidence).",
"entity_name": "CACNA1E",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:27:32.236773+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.7",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CACNA1E were changed from to Epileptic encephalopathy, early infantile, 69, MIM#618285",
"entity_name": "CACNA1E",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:27:01.725295+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CACNA1E were set to ",
"entity_name": "CACNA1E",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:26:32.468134+11:00",
"panel_name": "Genetic Epilepsy_AustralianGenomics_VCGS",
"panel_id": 202,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CACNA1E was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "CACNA1E",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:20:18.753148+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: CACNA1E was added\ngene: CACNA1E was added to Intellectual disability, syndromic and non-syndromic_GHQ. Sources: Expert list\nMode of inheritance for gene: CACNA1E was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: CACNA1E were set to 30343943\nPhenotypes for gene: CACNA1E were set to Epileptic encephalopathy, early infantile, 69, MIM#618285\nReview for gene: CACNA1E was set to GREEN\ngene: CACNA1E was marked as current diagnostic\nAdded comment: At least 30 unrelated patients reported with heterozygous variants in this gene; primarily a seizure disorder, often with profound intellectual disability. \nSources: Expert list",
"entity_name": "CACNA1E",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:12:54.411446+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CA8 as ready",
"entity_name": "CA8",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:12:54.403563+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ca8 has been classified as Green List (High Evidence).",
"entity_name": "CA8",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:12:49.827137+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.10",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: CA8 were changed from to Cerebellar ataxia and mental retardation with or without quadrupedal locomotion 3, MIM#613227",
"entity_name": "CA8",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:12:28.774750+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.9",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: CA8 were set to ",
"entity_name": "CA8",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:11:58.045848+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.8",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: CA8 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CA8",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:10:44.207439+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CA8 as ready",
"entity_name": "CA8",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:10:44.200382+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.69",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ca8 has been classified as Green List (High Evidence).",
"entity_name": "CA8",
"entity_type": "gene"
},
{
"created": "2019-11-25T17:02:42.895542+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CA8: Rating: GREEN; Mode of pathogenicity: None; Publications: 21937992, 19461874; Phenotypes: Cerebellar ataxia and mental retardation with or without quadrupedal locomotion 3, MIM#613227; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CA8",
"entity_type": "gene"
},
{
"created": "2019-11-25T16:52:57.130092+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CA2: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis, MIM#259730; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "CA2",
"entity_type": "gene"
},
{
"created": "2019-11-25T16:46:47.087612+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: C19orf12: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Neurodegeneration with brain iron accumulation 4, MIM#614298; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "C19orf12",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:48:15.882531+11:00",
"panel_name": "Early onset Parkinson disease_MelbourneGenomics_VCGS",
"panel_id": 26,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: PDE8B as ready",
"entity_name": "PDE8B",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:48:15.875264+11:00",
"panel_name": "Early onset Parkinson disease_MelbourneGenomics_VCGS",
"panel_id": 26,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pde8b has been classified as Green List (High Evidence).",
"entity_name": "PDE8B",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:48:11.092354+11:00",
"panel_name": "Early onset Parkinson disease_MelbourneGenomics_VCGS",
"panel_id": 26,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: PDE8B as Green List (high evidence)",
"entity_name": "PDE8B",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:48:11.084888+11:00",
"panel_name": "Early onset Parkinson disease_MelbourneGenomics_VCGS",
"panel_id": 26,
"panel_version": "0.2",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: pde8b has been classified as Green List (High Evidence).",
"entity_name": "PDE8B",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:47:41.549356+11:00",
"panel_name": "Early onset Parkinson disease_MelbourneGenomics_VCGS",
"panel_id": 26,
"panel_version": "0.1",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: PDE8B was added\ngene: PDE8B was added to Early onset Parkinson disease_MelbourneGenomics_VCGS. Sources: Expert Review\nMode of inheritance for gene: PDE8B was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: PDE8B were set to 20085714; 26769607; 26475694\nPhenotypes for gene: PDE8B were set to Striatal degeneration, autosomal dominant, MIM#609161\nReview for gene: PDE8B was set to GREEN\nAdded comment: Movement disorder due to basal ganglia abnormalities, at least three families reported with heterozygous variants in this gene. \nSources: Expert Review",
"entity_name": "PDE8B",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:38:02.988834+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IFIH1 as ready",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:38:02.980920+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ifih1 has been classified as Green List (High Evidence).",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:37:57.524934+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: IFIH1 as Green List (high evidence)",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:37:57.516561+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.6",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ifih1 has been classified as Green List (High Evidence).",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:37:30.274106+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: IFIH1 was added\ngene: IFIH1 was added to Regression_VCGS. Sources: Expert Review\nMode of inheritance for gene: IFIH1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: IFIH1 were set to 24686847\nPhenotypes for gene: IFIH1 were set to Aicardi-Goutieres syndrome 7, MIM#615846\nMode of pathogenicity for gene: IFIH1 was set to Other\nReview for gene: IFIH1 was set to GREEN\nAdded comment: Gain-of-function variants in this gene cause AGS, some affected individuals experience episodic neurological regression \nSources: Expert Review",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:26:50.884085+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TBCD as ready",
"entity_name": "TBCD",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:26:50.875808+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbcd has been classified as Green List (High Evidence).",
"entity_name": "TBCD",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:26:44.914155+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TBCD as Green List (high evidence)",
"entity_name": "TBCD",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:26:44.905384+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.4",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbcd has been classified as Green List (High Evidence).",
"entity_name": "TBCD",
"entity_type": "gene"
},
{
"created": "2019-11-24T17:26:15.542758+11:00",
"panel_name": "Regression_VCGS",
"panel_id": 206,
"panel_version": "0.3",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: TBCD was added\ngene: TBCD was added to Regression_VCGS. Sources: Expert Review\nMode of inheritance for gene: TBCD was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: TBCD were set to 27666370; 27666374\nPhenotypes for gene: TBCD were set to Encephalopathy, progressive, early-onset, with brain atrophy and thin corpus callosum, MIM#617193\nReview for gene: TBCD was set to GREEN\nAdded comment: 15 children from 9 unrelated families with bi-allelic variants in this gene and a progressive neurodegenerative encephalopathy. \nSources: Expert Review",
"entity_name": "TBCD",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:57:42.329455+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: BSND: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Bartter syndrome, type 4a, MIM#602522; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "BSND",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:47:04.570847+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: BRAT1: Rating: GREEN; Mode of pathogenicity: None; Publications: 26483087, 26494257, 27282546; Phenotypes: Neurodevelopmental disorder with cerebellar atrophy and with or without seizures, MIM#618056; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "BRAT1",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:41:34.996255+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: BMPER: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Diaphanospondylodysostosis, MIM#608022; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "BMPER",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:39:00.371677+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: BICD2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Spinal muscular atrophy, lower extremity-predominant, 2A, autosomal dominant, MIM#615290; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "BICD2",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:36:16.832835+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: BDNF as ready",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:36:16.825415+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: bdnf has been classified as Red List (Low Evidence).",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:36:07.499908+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: BDNF as Red List (low evidence)",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:36:07.491328+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.65",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: bdnf has been classified as Red List (Low Evidence).",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:35:42.733483+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: BDNF: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Central hypoventilation syndrome, congenital, MIM#209880; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:35:02.380345+11:00",
"panel_name": "Central Hypoventilation_VCGS",
"panel_id": 71,
"panel_version": "0.1",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: BDNF as ready",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:35:02.371669+11:00",
"panel_name": "Central Hypoventilation_VCGS",
"panel_id": 71,
"panel_version": "0.1",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: bdnf has been classified as Red List (Low Evidence).",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:34:58.308886+11:00",
"panel_name": "Central Hypoventilation_VCGS",
"panel_id": 71,
"panel_version": "0.1",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: BDNF as Red List (low evidence)",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:34:58.301114+11:00",
"panel_name": "Central Hypoventilation_VCGS",
"panel_id": 71,
"panel_version": "0.1",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: bdnf has been classified as Red List (Low Evidence).",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:34:29.485688+11:00",
"panel_name": "Central Hypoventilation_VCGS",
"panel_id": 71,
"panel_version": "0.0",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: BDNF: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Central hypoventilation syndrome, congenital, MIM#209880; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:33:44.846191+11:00",
"panel_name": "Intellectual disability, syndromic and non-syndromic_GHQ",
"panel_id": 250,
"panel_version": "0.5",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: BDNF: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Central hypoventilation syndrome, congenital, MIM#209880; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "BDNF",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:27:51.735484+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: BBIP1 as ready",
"entity_name": "BBIP1",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:27:51.728160+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: bbip1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "BBIP1",
"entity_type": "gene"
},
{
"created": "2019-11-24T13:27:27.455503+11:00",
"panel_name": "Mendeliome_VCGS",
"panel_id": 137,
"panel_version": "0.64",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: BBIP1 as Amber List (moderate evidence)",
"entity_name": "BBIP1",
"entity_type": "gene"
}
]
}