HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 221413,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=345",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=343",
"results": [
{
"created": "2024-11-15T15:23:52.365827+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6824",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: INPP5K as ready",
"entity_name": "INPP5K",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:23:52.355996+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6824",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: inpp5k has been classified as Green List (High Evidence).",
"entity_name": "INPP5K",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:23:47.539697+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6824",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: INPP5K were changed from to congenital muscular dystrophy with cataracts and intellectual disability MONDO:0024607",
"entity_name": "INPP5K",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:23:02.902594+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6823",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: INPP5K were set to ",
"entity_name": "INPP5K",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:22:24.100594+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6822",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: INPP5K was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "INPP5K",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:21:30.318330+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6821",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IKBKG as ready",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:21:30.308298+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6821",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ikbkg has been classified as Green List (High Evidence).",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:21:17.745326+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6821",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: IKBKG were changed from to Incontinentia pigmenti MONDO:0010631",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:20:34.708010+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6820",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: IKBKG were set to ",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2024-11-15T15:19:53.664988+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6819",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: IKBKG was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females",
"entity_name": "IKBKG",
"entity_type": "gene"
},
{
"created": "2024-11-15T14:24:51.749924+11:00",
"panel_name": "Prepair 1000+",
"panel_id": 3861,
"panel_version": "1.547",
"user_name": "Cassandra Muller",
"item_type": "entity",
"text": "reviewed gene: EYS: Rating: RED; Mode of pathogenicity: None; Publications: 20537394, 31074760; Phenotypes: Retinitis pigmentosa 25 (MIM#602772); Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "EYS",
"entity_type": "gene"
},
{
"created": "2024-11-15T12:36:29.312327+11:00",
"panel_name": "Prepair 1000+",
"panel_id": 3861,
"panel_version": "1.547",
"user_name": "Lauren Rogers",
"item_type": "entity",
"text": "reviewed gene: ACE: Rating: GREEN; Mode of pathogenicity: None; Publications: 16116425, 22095942; Phenotypes: Renal tubular dysgenesis, MIM# 267430; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "ACE",
"entity_type": "gene"
},
{
"created": "2024-11-15T12:02:45.990695+11:00",
"panel_name": "Muscular dystrophy and myopathy_Paediatric",
"panel_id": 141,
"panel_version": "1.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RFC4 as ready",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T12:02:45.976366+11:00",
"panel_name": "Muscular dystrophy and myopathy_Paediatric",
"panel_id": 141,
"panel_version": "1.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rfc4 has been classified as Green List (High Evidence).",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T12:02:38.297324+11:00",
"panel_name": "Muscular dystrophy and myopathy_Paediatric",
"panel_id": 141,
"panel_version": "1.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RFC4 were changed from Morimoto-Ryu-Malicdan neuromuscular syndrome, MIM# 621010 to Morimoto-Ryu-Malicdan neuromuscular syndrome, MIM# 621010",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T12:02:09.642558+11:00",
"panel_name": "Muscular dystrophy and myopathy_Paediatric",
"panel_id": 141,
"panel_version": "1.79",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RFC4 were changed from RFC4-related multisystem disorder to Morimoto-Ryu-Malicdan neuromuscular syndrome, MIM# 621010",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T12:01:13.464130+11:00",
"panel_name": "Muscular dystrophy and myopathy_Paediatric",
"panel_id": 141,
"panel_version": "1.78",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RFC4: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Morimoto-Ryu-Malicdan neuromuscular syndrome, MIM# 621010; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T12:00:03.711889+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2145",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RFC4 as ready",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T12:00:03.674857+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2145",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rfc4 has been classified as Green List (High Evidence).",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:59:56.195443+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2145",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RFC4 were changed from RFC4-related multisystem disorder to Morimoto-Ryu-Malicdan neuromuscular syndrome, MIM# 621010",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:59:09.971031+11:00",
"panel_name": "Cerebellar and Pontocerebellar Hypoplasia",
"panel_id": 72,
"panel_version": "1.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RFC4 as ready",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:59:09.953719+11:00",
"panel_name": "Cerebellar and Pontocerebellar Hypoplasia",
"panel_id": 72,
"panel_version": "1.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rfc4 has been classified as Green List (High Evidence).",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:58:17.684109+11:00",
"panel_name": "Cerebellar and Pontocerebellar Hypoplasia",
"panel_id": 72,
"panel_version": "1.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RFC4 were changed from RFC4-related multisystem disorder to Morimoto-Ryu-Malicdan neuromuscular syndrome, MIM# 621010",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:57:15.404284+11:00",
"panel_name": "Cerebellar and Pontocerebellar Hypoplasia",
"panel_id": 72,
"panel_version": "1.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: RFC4: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Morimoto-Ryu-Malicdan neuromuscular syndrome, MIM# 621010; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "RFC4",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:29:17.012159+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "1.294",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DHRSX were changed from congenital disorder of glycosylation, MONDO:0015286, DHRSX-related to Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:29:01.280856+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "1.293",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: DHRSX: Changed phenotypes: Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:28:30.059419+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6818",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DHRSX were changed from congenital disorder of glycosylation, MONDO:0015286, DHRSX-related to Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:27:49.826820+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6817",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: DHRSX: Changed phenotypes: Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:27:25.362616+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.206",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DHRSX were changed from congenital disorder of glycosylation, MONDO:0015286, DHRSX-related to Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:26:40.032582+11:00",
"panel_name": "Deafness_IsolatedAndComplex",
"panel_id": 209,
"panel_version": "1.205",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: DHRSX: Changed phenotypes: Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:25:54.411828+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DHRSX were changed from congenital disorder of glycosylation, MONDO:0015286, DHRSX-related to Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:24:53.302093+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "1.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: DHRSX: Changed phenotypes: Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:24:35.434737+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2144",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DHRSX were changed from congenital disorder of glycosylation, MONDO:0015286 to Congenital disorder of glycosylation, type 1DD, MIM# 301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-15T11:23:34.968621+11:00",
"panel_name": "Congenital Disorders of Glycosylation",
"panel_id": 68,
"panel_version": "1.56",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: DHRSX were changed from congenital disorder of glycosylation, MONDO:0015286, DHRSX-related to Congenital disorder of glycosylation, type 1DD, MIM#\t301133",
"entity_name": "DHRSX",
"entity_type": "gene"
},
{
"created": "2024-11-14T20:36:40.680269+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6817",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IFT172 as ready",
"entity_name": "IFT172",
"entity_type": "gene"
},
{
"created": "2024-11-14T20:36:40.670314+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6817",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ift172 has been classified as Green List (High Evidence).",
"entity_name": "IFT172",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:56:10.748252+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6817",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: IFT172 were changed from to Bardet-Biedl syndrome MONDO:0015229",
"entity_name": "IFT172",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:55:31.870735+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6816",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: IFT172 were set to ",
"entity_name": "IFT172",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:54:55.656809+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6815",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: IFT172 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "IFT172",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:53:58.327336+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6814",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IFIH1 as ready",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:53:58.309560+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6814",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ifih1 has been classified as Green List (High Evidence).",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:53:54.062539+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6814",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: IFIH1 were changed from to IFIH1-related type 1 interferonopathy MONDO:0700262",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:53:15.207462+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6813",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: IFIH1 were set to ",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:50:50.013372+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6812",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: IFIH1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "IFIH1",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:49:17.469520+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6811",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IDUA as ready",
"entity_name": "IDUA",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:49:17.456725+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6811",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: idua has been classified as Green List (High Evidence).",
"entity_name": "IDUA",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:48:48.221936+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6811",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: IDUA were changed from to mucopolysaccharidosis type 1 MONDO:0001586",
"entity_name": "IDUA",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:48:04.308506+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6810",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: IDUA were set to 20301341",
"entity_name": "IDUA",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:47:29.343869+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6809",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: IDUA were set to ",
"entity_name": "IDUA",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:39:45.814747+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6808",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: IDUA was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "IDUA",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:38:42.949763+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6807",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IDS as ready",
"entity_name": "IDS",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:38:42.936858+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6807",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ids has been classified as Green List (High Evidence).",
"entity_name": "IDS",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:38:36.085434+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6807",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: IDS were changed from to mucopolysaccharidosis type 2 MONDO:0010674",
"entity_name": "IDS",
"entity_type": "gene"
},
{
"created": "2024-11-14T19:36:07.314991+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6806",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: IDS were set to ",
"entity_name": "IDS",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:59:46.222571+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6805",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: IDS was changed from Unknown to X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)",
"entity_name": "IDS",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:58:57.424204+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6804",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IDH2 as ready",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:58:57.393968+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6804",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: idh2 has been classified as Green List (High Evidence).",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:58:47.209495+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6804",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: IDH2 were changed from to mitochondrial disease MONDO:0044970",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:57:52.557841+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6803",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: IDH2 were set to ",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:57:06.916803+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6802",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: IDH2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "IDH2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:56:18.206045+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6801",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HTRA2 as ready",
"entity_name": "HTRA2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:56:18.194366+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6801",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: htra2 has been classified as Green List (High Evidence).",
"entity_name": "HTRA2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:56:13.734549+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6801",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HTRA2 were changed from to 3-methylglutaconic aciduria type 8 MONDO:0044723",
"entity_name": "HTRA2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:55:27.850687+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6800",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HTRA2 were set to ",
"entity_name": "HTRA2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:54:34.503890+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6799",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HTRA2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HTRA2",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:53:29.436623+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6798",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HSPD1 as ready",
"entity_name": "HSPD1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:53:29.414883+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6798",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hspd1 has been classified as Green List (High Evidence).",
"entity_name": "HSPD1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:52:33.125281+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6798",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HSPD1 were changed from Leukodystrophy, hypomyelinating, 4, MIM# 612233 to Leukodystrophy, hypomyelinating, 4, MIM# 612233",
"entity_name": "HSPD1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:30:22.518401+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6797",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HSPD1 were changed from Leukodystrophy, hypomyelinating, 4, MIM# 612233 to Leukodystrophy, hypomyelinating, 4, MIM# 612233",
"entity_name": "HSPD1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:29:44.190873+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6796",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HSPD1 were changed from to Leukodystrophy, hypomyelinating, 4, MIM# 612233",
"entity_name": "HSPD1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:28:56.515912+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6795",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HSPD1 were set to ",
"entity_name": "HSPD1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:28:15.086954+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6794",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HSPD1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HSPD1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:27:39.819528+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6793",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: HSPD1: Rating: GREEN; Mode of pathogenicity: None; Publications: 18571143, 27405012, 32532876, 28377887, 27405012, 11898127, 17420924; Phenotypes: Leukodystrophy, hypomyelinating, 4, MIM# 612233; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HSPD1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:25:28.187710+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6793",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HSD17B10 were changed from HSD10 mitochondrial disease MONDO:0010327 to HSD10 mitochondrial disease MONDO:0010327",
"entity_name": "HSD17B10",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:25:12.768047+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6792",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HSD17B10 as ready",
"entity_name": "HSD17B10",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:25:12.753296+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6792",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hsd17b10 has been classified as Green List (High Evidence).",
"entity_name": "HSD17B10",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:24:06.611160+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6792",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HSD17B10 were changed from to HSD10 mitochondrial disease MONDO:0010327",
"entity_name": "HSD17B10",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:23:14.815722+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6791",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HSD17B10 were set to ",
"entity_name": "HSD17B10",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:22:24.726232+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6790",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HSD17B10 was changed from Unknown to X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)",
"entity_name": "HSD17B10",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:21:01.554461+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6789",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HPRT1 as ready",
"entity_name": "HPRT1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:21:01.526598+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6789",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hprt1 has been classified as Green List (High Evidence).",
"entity_name": "HPRT1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:20:56.742056+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6789",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HPRT1 were changed from to Lesch-Nyhan syndrome MONDO:0010298",
"entity_name": "HPRT1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:20:09.568781+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6788",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HPRT1 were set to ",
"entity_name": "HPRT1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:19:26.961147+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6787",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HPRT1 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females",
"entity_name": "HPRT1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:18:30.494329+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6786",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HPD as ready",
"entity_name": "HPD",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:18:30.473665+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6786",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hpd has been classified as Green List (High Evidence).",
"entity_name": "HPD",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:18:22.582862+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6786",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HPD were changed from to tyrosinemia type III MONDO:0010162",
"entity_name": "HPD",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:16:19.534730+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6785",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HPD were set to ",
"entity_name": "HPD",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:15:31.187987+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6784",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HPD was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HPD",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:14:42.776709+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6783",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: HPD: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: tyrosinemia type III MONDO:0010162; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HPD",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:12:35.494007+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6783",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HOXA1 as ready",
"entity_name": "HOXA1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:12:35.480282+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6783",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hoxa1 has been classified as Green List (High Evidence).",
"entity_name": "HOXA1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:12:25.501199+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6783",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HOXA1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "HOXA1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:11:48.106732+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6782",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HOXA1 were set to ",
"entity_name": "HOXA1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:11:10.202814+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6781",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HOXA1 were changed from to Bosley-Salih-Alorainy syndrome, MIM#601536 and Athabaskan brainstem dysgenesis syndrome, MIM#601536",
"entity_name": "HOXA1",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:09:58.036956+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6780",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: HNRNPK as ready",
"entity_name": "HNRNPK",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:09:58.021999+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6780",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: hnrnpk has been classified as Green List (High Evidence).",
"entity_name": "HNRNPK",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:09:51.805981+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6780",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: HNRNPK were changed from to neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-hip dysplasia syndrome (Au-Kline syndrome) MONDO:0018681",
"entity_name": "HNRNPK",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:09:13.172607+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6779",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: HNRNPK were set to ",
"entity_name": "HNRNPK",
"entity_type": "gene"
},
{
"created": "2024-11-14T18:07:52.511731+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6778",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: HNRNPK was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "HNRNPK",
"entity_type": "gene"
}
]
}