HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 221415,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=376",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=374",
"results": [
{
"created": "2024-10-03T18:01:19.374809+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6365",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NPC2 as ready",
"entity_name": "NPC2",
"entity_type": "gene"
},
{
"created": "2024-10-03T18:01:19.361511+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6365",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: npc2 has been classified as Green List (High Evidence).",
"entity_name": "NPC2",
"entity_type": "gene"
},
{
"created": "2024-10-03T18:00:57.875153+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6365",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NPC2 were changed from to Niemann-pick disease, type C2, MIM# 607625; MONDO:0011873",
"entity_name": "NPC2",
"entity_type": "gene"
},
{
"created": "2024-10-03T18:00:07.700478+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6364",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NPC2 were set to 11125141; 17470133",
"entity_name": "NPC2",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:59:17.995594+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6363",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NPC2 were set to ",
"entity_name": "NPC2",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:58:25.513287+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6362",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NPC2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NPC2",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:57:31.235080+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6361",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NPC1 as ready",
"entity_name": "NPC1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:57:31.217325+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6361",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: npc1 has been classified as Green List (High Evidence).",
"entity_name": "NPC1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:57:18.683716+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6361",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NPC1 were changed from to Niemann-Pick disease, type C1 and type D, MIM# 257220; MONDO:0009757",
"entity_name": "NPC1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:56:38.157162+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6360",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NPC1 were set to ",
"entity_name": "NPC1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:55:55.112691+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6359",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NPC1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NPC1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:54:18.178575+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6358",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NKX2-1 as ready",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:54:18.151679+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6358",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nkx2-1 has been classified as Green List (High Evidence).",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:54:05.437284+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6358",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NKX2-1 were changed from Choreoathetosis, hypothyroidism, and neonatal respiratory distress MIM#610978 to Choreoathetosis, hypothyroidism, and neonatal respiratory distress MIM#610978",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:49:36.387504+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6357",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NKX2-1 were changed from to Choreoathetosis, hypothyroidism, and neonatal respiratory distress MIM#610978",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:48:47.789564+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6356",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NKX2-1 were set to 10931427; 27066577; 26839702; 26103969; 23911641; 11854319; 24714694",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:45:58.239724+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6355",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NKX2-1 were set to ",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:44:50.775698+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6354",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NKX2-1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:43:46.559127+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6353",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NGLY1 as ready",
"entity_name": "NGLY1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:43:46.544532+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6353",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ngly1 has been classified as Green List (High Evidence).",
"entity_name": "NGLY1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:43:40.208189+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6353",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NGLY1 were changed from to Congenital disorder of deglycosylation (OMIM 615273)",
"entity_name": "NGLY1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:42:50.742226+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6352",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: NGLY1: Rating: GREEN; Mode of pathogenicity: None; Publications: 24651605, 27388694, 32259258; Phenotypes: Congenital disorder of deglycosylation (OMIM 615273); Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NGLY1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:42:20.149338+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6352",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NGLY1 were set to ",
"entity_name": "NGLY1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:41:27.172025+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6351",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NGLY1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NGLY1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:40:28.469103+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6350",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NFIX as ready",
"entity_name": "NFIX",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:40:28.438263+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6350",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nfix has been classified as Green List (High Evidence).",
"entity_name": "NFIX",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:40:15.399895+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6350",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NFIX were changed from to Sotos syndrome 2 (MIM#614753); Marshall-Smith syndrome, MIM# 602535",
"entity_name": "NFIX",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:39:27.944812+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6349",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NFIX were set to 33034087; 29897170; 30548146; 25118028",
"entity_name": "NFIX",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:38:35.979773+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6348",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NFIX were set to ",
"entity_name": "NFIX",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:37:25.449642+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6347",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NFIX was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "NFIX",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:36:29.787010+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6346",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NEU1 as ready",
"entity_name": "NEU1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:36:29.773373+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6346",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: neu1 has been classified as Green List (High Evidence).",
"entity_name": "NEU1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:36:20.271196+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6346",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NEU1 were changed from to Sialidosis, type I and type II, MIM# 256550; MONDO:0009738",
"entity_name": "NEU1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:32:31.960070+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6345",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NEU1 were set to ",
"entity_name": "NEU1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:31:43.080889+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6344",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NEU1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NEU1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:30:47.042267+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6343",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NDUFV1 as ready",
"entity_name": "NDUFV1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:30:47.026961+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6343",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ndufv1 has been classified as Green List (High Evidence).",
"entity_name": "NDUFV1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:30:39.839361+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6343",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NDUFV1 were changed from to Mitochondrial complex I deficiency, nuclear type 4 MIM#618225",
"entity_name": "NDUFV1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:29:36.754829+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6342",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NDUFV1 were set to ",
"entity_name": "NDUFV1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:28:58.246796+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6341",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NDUFV1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NDUFV1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:28:08.633172+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6340",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NDUFS7 as ready",
"entity_name": "NDUFS7",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:28:08.607651+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6340",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ndufs7 has been classified as Green List (High Evidence).",
"entity_name": "NDUFS7",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:28:04.592763+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6340",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NDUFS7 were changed from to Mitochondrial complex I deficiency, nuclear type 3 (MIM# 618224)",
"entity_name": "NDUFS7",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:27:11.334918+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6339",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NDUFS7 were set to ",
"entity_name": "NDUFS7",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:26:32.241992+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6338",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NDUFS7 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NDUFS7",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:25:32.624600+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6337",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NDUFA1 as ready",
"entity_name": "NDUFA1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:25:32.592920+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6337",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ndufa1 has been classified as Green List (High Evidence).",
"entity_name": "NDUFA1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:25:26.212928+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6337",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NDUFA1 were changed from Mitochondrial complex I deficiency, nuclear type 12 MIM#301020 to Mitochondrial complex I deficiency, nuclear type 12 MIM#301020",
"entity_name": "NDUFA1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:24:50.356038+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6336",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NDUFA1 were changed from to Mitochondrial complex I deficiency, nuclear type 12 MIM#301020",
"entity_name": "NDUFA1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:24:07.998073+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6335",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NDUFA1 were set to ",
"entity_name": "NDUFA1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:20:25.529211+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6334",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NDUFA1 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females",
"entity_name": "NDUFA1",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:18:58.774371+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6333",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NALCN as ready",
"entity_name": "NALCN",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:18:58.759475+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6333",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nalcn has been classified as Green List (High Evidence).",
"entity_name": "NALCN",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:18:49.405139+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6333",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NALCN were changed from to Congenital contractures of the limbs and face, hypotonia, and developmental delay, MIM# 616266; Hypotonia, infantile, with psychomotor retardation and characteristic facies 1, MIM # 615419",
"entity_name": "NALCN",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:11:51.768405+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6332",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NALCN were set to ",
"entity_name": "NALCN",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:11:00.229675+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6331",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NALCN was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "NALCN",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:10:00.376314+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6330",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NAGLU as ready",
"entity_name": "NAGLU",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:10:00.344510+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6330",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: naglu has been classified as Green List (High Evidence).",
"entity_name": "NAGLU",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:09:50.722957+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6330",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NAGLU were changed from to Mucopolysaccharidosis type IIIB (Sanfilippo B), MIM# 252920",
"entity_name": "NAGLU",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:09:11.833849+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6329",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NAGLU were set to ",
"entity_name": "NAGLU",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:08:10.732057+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6328",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NAGLU was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NAGLU",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:03:05.089128+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6327",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NAGA as ready",
"entity_name": "NAGA",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:03:05.067697+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6327",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: naga has been classified as Green List (High Evidence).",
"entity_name": "NAGA",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:02:16.431040+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6327",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NAGA were changed from Kanzaki disease, MIM# 609242; Schindler disease, type I and type II 609241; alpha-N-acetylgalactosaminidase deficiency MONDO:0017779 to Kanzaki disease, MIM# 609242; Schindler disease, type I and type II 609241; alpha-N-acetylgalactosaminidase deficiency MONDO:0017779",
"entity_name": "NAGA",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:01:52.410798+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6327",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: NAGA were changed from to Kanzaki disease, MIM# 609242; Schindler disease, type I and type II 609241; alpha-N-acetylgalactosaminidase deficiency MONDO:0017779",
"entity_name": "NAGA",
"entity_type": "gene"
},
{
"created": "2024-10-03T17:00:56.896422+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6326",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: NAGA were set to ",
"entity_name": "NAGA",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:59:59.584365+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6325",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: NAGA was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "NAGA",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:58:55.876007+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6324",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SCO2 as ready",
"entity_name": "SCO2",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:58:55.846188+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6324",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: sco2 has been classified as Green List (High Evidence).",
"entity_name": "SCO2",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:58:50.614800+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6324",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SCO2 were changed from to Mitochondrial complex IV deficiency, nuclear type 2, MIM# 604377",
"entity_name": "SCO2",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:58:08.835336+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6323",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: SCO2 were set to ",
"entity_name": "SCO2",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:57:25.282263+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6322",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: SCO2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "SCO2",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:55:47.673307+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6321",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SKI as ready",
"entity_name": "SKI",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:55:47.605493+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6321",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: ski has been classified as Green List (High Evidence).",
"entity_name": "SKI",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:55:36.916868+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6321",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SKI were changed from to Shprintzen-Goldberg syndrome, MIM# 182212; Neurodevelopmental disorder, MONDO:0700092, SKI-related",
"entity_name": "SKI",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:55:02.212191+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6320",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: SKI were set to ",
"entity_name": "SKI",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:50:01.648918+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6319",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: SKI was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "SKI",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:49:17.424368+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6318",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: SKI: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Neurodevelopmental disorder, MONDO:0700092, SKI-related; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "SKI",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:47:41.987840+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6318",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: SHH as ready",
"entity_name": "SHH",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:47:41.973272+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6318",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: shh has been classified as Green List (High Evidence).",
"entity_name": "SHH",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:47:34.812512+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6318",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: SHH were changed from to Holoprosencephaly 3 (MIM#142945)",
"entity_name": "SHH",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:46:41.050910+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6317",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: SHH were set to ",
"entity_name": "SHH",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:45:03.908865+10:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.6316",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: SHH was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "SHH",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:43:52.360561+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2047",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IL7 as ready",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:43:52.348221+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2047",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: il7 has been classified as Green List (High Evidence).",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:43:39.181549+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2047",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: IL7 as Green List (high evidence)",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:43:39.161165+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2047",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: il7 has been classified as Green List (High Evidence).",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:43:12.589137+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2046",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: IL7 was added\ngene: IL7 was added to Mendeliome. Sources: Literature\nMode of inheritance for gene: IL7 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: IL7 were set to 39352394\nPhenotypes for gene: IL7 were set to Combined immunodeficiency, MONDO:0015131, IL7-related\nReview for gene: IL7 was set to GREEN\nAdded comment: 6 indviduals from 4 kindreds with combined immune deficiency and recurrent infections. Extensive immunophenotyping revealing IL7 dependent and independent development of T cells. \nSources: Literature",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:42:40.415831+10:00",
"panel_name": "Combined Immunodeficiency",
"panel_id": 223,
"panel_version": "1.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IL7 as ready",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:42:40.404849+10:00",
"panel_name": "Combined Immunodeficiency",
"panel_id": 223,
"panel_version": "1.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: il7 has been classified as Green List (High Evidence).",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:41:36.590147+10:00",
"panel_name": "Combined Immunodeficiency",
"panel_id": 223,
"panel_version": "1.73",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: IL7 were changed from Combined Immune deficiency to Combined immunodeficiency, MONDO:0015131, IL7-related",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:40:37.059924+10:00",
"panel_name": "Combined Immunodeficiency",
"panel_id": 223,
"panel_version": "1.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: IL7 as Green List (high evidence)",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:40:37.050785+10:00",
"panel_name": "Combined Immunodeficiency",
"panel_id": 223,
"panel_version": "1.72",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: il7 has been classified as Green List (High Evidence).",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:40:00.404621+10:00",
"panel_name": "Combined Immunodeficiency",
"panel_id": 223,
"panel_version": "1.71",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: IL7: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Combined immunodeficiency, MONDO:0015131, IL7-related; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "IL7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:37:28.930305+10:00",
"panel_name": "Severe early-onset obesity",
"panel_id": 3764,
"panel_version": "1.12",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: LRRC7 as ready",
"entity_name": "LRRC7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:37:28.916636+10:00",
"panel_name": "Severe early-onset obesity",
"panel_id": 3764,
"panel_version": "1.12",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lrrc7 has been classified as Green List (High Evidence).",
"entity_name": "LRRC7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:37:16.394315+10:00",
"panel_name": "Severe early-onset obesity",
"panel_id": 3764,
"panel_version": "1.12",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: LRRC7 as Green List (high evidence)",
"entity_name": "LRRC7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:37:16.378974+10:00",
"panel_name": "Severe early-onset obesity",
"panel_id": 3764,
"panel_version": "1.12",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: lrrc7 has been classified as Green List (High Evidence).",
"entity_name": "LRRC7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:36:57.076036+10:00",
"panel_name": "Severe early-onset obesity",
"panel_id": 3764,
"panel_version": "1.11",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: LRRC7 was added\ngene: LRRC7 was added to Severe early-onset obesity. Sources: Literature\nMode of inheritance for gene: LRRC7 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: LRRC7 were set to 39256359\nPhenotypes for gene: LRRC7 were set to neurodevelopmental disorder (MONDO:0700092), LRRC7-related\nReview for gene: LRRC7 was set to GREEN\nAdded comment: Over 30 individuals reported with a neurodevelopmental disorder and variants in this gene. Hyperphagia and early-onset obesity is a common feature. \nSources: Literature",
"entity_name": "LRRC7",
"entity_type": "gene"
},
{
"created": "2024-10-03T16:36:10.876065+10:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "1.2045",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: LRRC7 as ready",
"entity_name": "LRRC7",
"entity_type": "gene"
}
]
}