HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 220324,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=914",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=912",
"results": [
{
"created": "2022-03-26T13:47:45.060264+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11983",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TERC were changed from to Dyskeratosis congenita, autosomal dominant 1, MIM# 127550",
"entity_name": "TERC",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:47:24.825070+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11982",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TERC were set to ",
"entity_name": "TERC",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:47:03.825774+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11981",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TERC was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TERC",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:46:43.980196+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11980",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TERC: Rating: GREEN; Mode of pathogenicity: None; Publications: 11574891; Phenotypes: Dyskeratosis congenita, autosomal dominant 1, MIM# 127550; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TERC",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:44:43.467945+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11980",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TEK as ready",
"entity_name": "TEK",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:44:43.453465+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11980",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tek has been classified as Green List (High Evidence).",
"entity_name": "TEK",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:44:35.924045+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11980",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TEK were changed from to Glaucoma 3, primary congenital, E, MIM# 617272; Venous malformations, multiple cutaneous and mucosal, MIM# 600195",
"entity_name": "TEK",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:44:16.162159+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11979",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TEK were set to ",
"entity_name": "TEK",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:43:56.659348+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11978",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TEK was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TEK",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:43:38.314895+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11977",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TEK: Rating: GREEN; Mode of pathogenicity: None; Publications: 27270174, 19888299; Phenotypes: Glaucoma 3, primary congenital, E, MIM# 617272, Venous malformations, multiple cutaneous and mucosal, MIM# 600195; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TEK",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:41:13.672772+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11977",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TEAD1 as ready",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:41:13.661603+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11977",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tead1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:41:04.700066+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11977",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TEAD1 were changed from to Sveinsson chorioretinal atrophy, MIM# 108985",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:40:38.996790+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11976",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: TEAD1: Changed rating: AMBER; Changed publications: 26091538, 15016762, 33864784, 17689488, 30903741",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:40:07.246912+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11976",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TEAD1 were set to ",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:39:43.722792+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11975",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "changed review comment from: Sveinsson chorioretinal atrophy (SCRA) is characterized by bilateral, well-defined, tongue-shaped strips of atrophic retina and choroid that extend from the optic nerve into the peripheral ocular fundus. The lesions may be evident at birth and usually progress at a variable rate, sometimes leading to central visual loss. Separate small distinct circular atrophic lesions are observed in the peripheral ocular fundus in some patients. Congenital anterior polar cataracts are found in approximately 25% of affected individuals.\r\n\r\nThe vast majority of reported cases were of Icelandic origin but the characteristic clinical picture of SCRA is also described in patients of non-Icelandic descent. The variant reported in the Icelanding population is (c.1261T>C, p.Tyr421His), another variant at same position c.1261T>A, p.Tyr421Asn also reported in non-Icelandic family.\r\n\r\nFunctional data supports gene-disease association.; to: Sveinsson chorioretinal atrophy (SCRA) is characterized by bilateral, well-defined, tongue-shaped strips of atrophic retina and choroid that extend from the optic nerve into the peripheral ocular fundus. The lesions may be evident at birth and usually progress at a variable rate, sometimes leading to central visual loss. Separate small distinct circular atrophic lesions are observed in the peripheral ocular fundus in some patients. Congenital anterior polar cataracts are found in approximately 25% of affected individuals.\r\n\r\nThe vast majority of reported cases were of Icelandic origin but the characteristic clinical picture of SCRA is also described in patients of non-Icelandic descent. The variant reported in the Icelanding population is (c.1261T>C, p.Tyr421His), another variant at same position c.1261T>A, p.Tyr421Asn also reported in non-Icelandic family.\r\n\r\nA de novo nonsense variant has also been reported in a case with Aicardi syndrome with infantile spasms, agenesis of the corpus callosum, and chorioretinal lacunae. ",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:39:11.640745+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11975",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TEAD1 as Amber List (moderate evidence)",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:39:11.623242+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11975",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tead1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:37:58.813636+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11974",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TEAD1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:37:39.404615+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11973",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TEAD1: Rating: GREEN; Mode of pathogenicity: None; Publications: 15016762, 33864784, 17689488, 30903741; Phenotypes: Sveinsson chorioretinal atrophy, MIM# 108985; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TEAD1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:32:24.895986+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.457",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TDP1 as ready",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:32:24.885292+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.457",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tdp1 has been classified as Red List (Low Evidence).",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:32:07.405666+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.457",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TDP1 were changed from to Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 , MIM# 607250",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:31:38.209998+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.456",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TDP1 were set to ",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:31:08.486965+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.455",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TDP1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:30:28.159328+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.454",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TDP1 as Red List (low evidence)",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:30:28.148382+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.454",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tdp1 has been classified as Red List (Low Evidence).",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:28:53.299099+11:00",
"panel_name": "Hereditary Neuropathy - complex",
"panel_id": 3070,
"panel_version": "0.123",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag founder tag was added to gene: TDP1.",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:28:37.770218+11:00",
"panel_name": "Hereditary Neuropathy - complex",
"panel_id": 3070,
"panel_version": "0.123",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TDP1 as ready",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:28:37.752967+11:00",
"panel_name": "Hereditary Neuropathy - complex",
"panel_id": 3070,
"panel_version": "0.123",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tdp1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:28:34.901300+11:00",
"panel_name": "Hereditary Neuropathy - complex",
"panel_id": 3070,
"panel_version": "0.123",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TDP1 were changed from Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1; HMSN to Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 , MIM# 607250",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:28:18.448742+11:00",
"panel_name": "Regression",
"panel_id": 206,
"panel_version": "0.453",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TDP1: Rating: RED; Mode of pathogenicity: None; Publications: 31182267, 12244316; Phenotypes: Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 , MIM# 607250; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:28:11.075767+11:00",
"panel_name": "Hereditary Neuropathy - complex",
"panel_id": 3070,
"panel_version": "0.122",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TDP1 were set to 31182267",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:27:22.928908+11:00",
"panel_name": "Hereditary Neuropathy - complex",
"panel_id": 3070,
"panel_version": "0.121",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TDP1 as Amber List (moderate evidence)",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:27:22.916734+11:00",
"panel_name": "Hereditary Neuropathy - complex",
"panel_id": 3070,
"panel_version": "0.121",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tdp1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:26:54.796724+11:00",
"panel_name": "Hereditary Neuropathy - complex",
"panel_id": 3070,
"panel_version": "0.120",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TDP1: Rating: AMBER; Mode of pathogenicity: None; Publications: 31182267, 12244316; Phenotypes: Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 , MIM# 607250; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:24:40.294832+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11973",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Tag founder tag was added to gene: TDP1.",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:24:21.155922+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11973",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TDP1 were changed from to Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 , MIM# 607250",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:24:06.471216+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11972",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TDP1 were set to ",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:23:47.113457+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11971",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TDP1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:23:28.424856+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11970",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TDP1 as Amber List (moderate evidence)",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:23:28.406913+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11970",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tdp1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:23:09.243283+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11969",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TDP1: Rating: AMBER; Mode of pathogenicity: None; Publications: 31182267, 12244316; Phenotypes: Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 , MIM# 607250; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TDP1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:18:24.266504+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11969",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TCIRG1 as ready",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:18:24.253967+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11969",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tcirg1 has been classified as Green List (High Evidence).",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:18:16.605911+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11969",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TCIRG1 were changed from to Osteopetrosis, autosomal recessive 1, MIM# 259700",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:17:57.171330+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11968",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TCIRG1 were set to ",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:17:37.788272+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11967",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TCIRG1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:17:19.053525+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11966",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TCIRG1: Rating: GREEN; Mode of pathogenicity: None; Publications: 34624559, 34210262, 30084437, 28816234; Phenotypes: Osteopetrosis, autosomal recessive 1, MIM# 259700; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TCIRG1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:14:24.573066+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11966",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TCF4 as ready",
"entity_name": "TCF4",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:14:24.561867+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11966",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tcf4 has been classified as Green List (High Evidence).",
"entity_name": "TCF4",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:14:16.815397+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11966",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TCF4 were changed from to Pitt-Hopkins syndrome, MIM# 610954",
"entity_name": "TCF4",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:13:57.503704+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11965",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TCF4 were set to ",
"entity_name": "TCF4",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:13:37.838740+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11964",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TCF4 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TCF4",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:13:19.552998+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11963",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TCF4: Rating: GREEN; Mode of pathogenicity: None; Publications: 18728071, 22934316; Phenotypes: Pitt-Hopkins syndrome, MIM# 610954; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TCF4",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:09:52.206215+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11963",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TCAP as ready",
"entity_name": "TCAP",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:09:52.195521+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11963",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tcap has been classified as Green List (High Evidence).",
"entity_name": "TCAP",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:09:43.051777+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11963",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TCAP were changed from to Muscular dystrophy, limb-girdle, autosomal recessive 7, MIM# 601954",
"entity_name": "TCAP",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:09:20.798628+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11962",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TCAP was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TCAP",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:08:58.010474+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11961",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TCAP: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Muscular dystrophy, limb-girdle, autosomal recessive 7, MIM# 601954; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TCAP",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:06:04.025634+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11961",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TBX5 as ready",
"entity_name": "TBX5",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:06:04.014735+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11961",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbx5 has been classified as Green List (High Evidence).",
"entity_name": "TBX5",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:05:52.631355+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11961",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TBX5 were changed from to Holt-Oram syndrome, MIM# 142900",
"entity_name": "TBX5",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:05:34.171177+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11960",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TBX5 were set to ",
"entity_name": "TBX5",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:05:12.480291+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11959",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TBX5 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TBX5",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:04:17.150060+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11958",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TBX20 as ready",
"entity_name": "TBX20",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:04:17.138267+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11958",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbx20 has been classified as Green List (High Evidence).",
"entity_name": "TBX20",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:04:09.428462+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11958",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TBX20 were changed from to Atrial septal defect 4, MIM# 611363",
"entity_name": "TBX20",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:03:47.125157+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11957",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TBX20 were set to ",
"entity_name": "TBX20",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:03:27.586061+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11956",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TBX20 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TBX20",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:03:06.635159+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11955",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TBX20: Rating: GREEN; Mode of pathogenicity: None; Publications: 17668378, 19762328, 33585493, 29089047; Phenotypes: Atrial septal defect 4, MIM# 611363; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TBX20",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:01:11.104778+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4610",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TBL1XR1 as ready",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:01:11.095296+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4610",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbl1xr1 has been classified as Green List (High Evidence).",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T13:01:04.421551+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4610",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TBL1XR1 were changed from to Mental retardation, autosomal dominant 41, MIM# 616944; Pierpont syndrome, MIM# 602342",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:55:44.581467+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4609",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TBL1XR1 were set to ",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:55:12.334352+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4608",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TBL1XR1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:54:38.091784+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4607",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TBL1XR1: Rating: GREEN; Mode of pathogenicity: None; Publications: 26769062, 30365874, 25425123, 9450851, 23160955, 28687524, 23176139, 16007632; Phenotypes: Mental retardation, autosomal dominant 41, MIM# 616944, Pierpont syndrome, MIM# 602342; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:53:31.577275+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11955",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TBL1XR1 as ready",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:53:31.566824+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11955",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbl1xr1 has been classified as Green List (High Evidence).",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:53:23.008908+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11955",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TBL1XR1 were changed from to Mental retardation, autosomal dominant 41, MIM# 616944; Pierpont syndrome, MIM# 602342",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:52:56.148755+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11954",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TBL1XR1 were set to ",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:52:35.123576+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11953",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TBL1XR1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:52:16.684244+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11952",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TBL1XR1: Rating: GREEN; Mode of pathogenicity: None; Publications: 26769062, 30365874, 25425123, 9450851, 23160955, 28687524, 23176139, 16007632; Phenotypes: Mental retardation, autosomal dominant 41, MIM# 616944, Pierpont syndrome, MIM# 602342; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:50:11.493929+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "1.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TBL1XR1 as Amber List (moderate evidence)",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T12:50:11.482545+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "1.13",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbl1xr1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "TBL1XR1",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:35:27.369628+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "0.1511",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TBCK as ready",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:35:27.354110+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "0.1511",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbck has been classified as Green List (High Evidence).",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:35:21.468401+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "0.1511",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TBCK were changed from to Hypotonia, infantile, with psychomotor retardation and characteristic facies 3, MIM# 616900",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:34:45.149117+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "0.1510",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TBCK were set to ",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:34:04.767479+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "0.1509",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TBCK was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:33:27.479381+11:00",
"panel_name": "Genetic Epilepsy",
"panel_id": 202,
"panel_version": "0.1508",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TBCK: Rating: GREEN; Mode of pathogenicity: None; Publications: 27040692, 30103036, 27040691; Phenotypes: Hypotonia, infantile, with psychomotor retardation and characteristic facies 3, MIM# 616900; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:32:58.291235+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4607",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TBCK as ready",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:32:58.274674+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4607",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbck has been classified as Green List (High Evidence).",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:32:41.865946+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4607",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TBCK were changed from to Hypotonia, infantile, with psychomotor retardation and characteristic facies 3, MIM# 616900",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:32:10.896935+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4606",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TBCK were set to ",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:31:39.327551+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4605",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: TBCK was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:31:04.872214+11:00",
"panel_name": "Intellectual disability syndromic and non-syndromic",
"panel_id": 250,
"panel_version": "0.4604",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TBCK: Rating: GREEN; Mode of pathogenicity: None; Publications: 27040692, 30103036, 27040691; Phenotypes: Hypotonia, infantile, with psychomotor retardation and characteristic facies 3, MIM# 616900; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:30:32.130100+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11952",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TBCK as ready",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:30:32.119641+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11952",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tbck has been classified as Green List (High Evidence).",
"entity_name": "TBCK",
"entity_type": "gene"
},
{
"created": "2022-03-26T09:30:23.998465+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11952",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TBCK were changed from to Hypotonia, infantile, with psychomotor retardation and characteristic facies 3, MIM# 616900",
"entity_name": "TBCK",
"entity_type": "gene"
}
]
}