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{
"count": 220751,
"next": "https://panelapp-aus.org/api/v1/activities/?format=api&page=983",
"previous": "https://panelapp-aus.org/api/v1/activities/?format=api&page=981",
"results": [
{
"created": "2022-02-21T20:15:41.121251+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3750",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: ROR2 were set to ",
"entity_name": "ROR2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:14:59.538251+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3749",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: ROR2 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal",
"entity_name": "ROR2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:14:27.784047+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3748",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RNASET2 as ready",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:14:27.774355+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3748",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnaset2 has been classified as Amber List (Moderate Evidence).",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:14:23.615546+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3748",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RNASET2 were changed from LEUKOENCEPHALOPATHY, CYSTIC, WITHOUT MEGALENCEPHALY to Leukoencephalopathy, cystic, without megalencephaly MIM#612951",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:14:06.717233+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3747",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RNASET2 were set to ",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:13:42.285944+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3746",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: RNASET2 as Amber List (moderate evidence)",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:13:42.271735+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3746",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnaset2 has been classified as Amber List (Moderate Evidence).",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:13:16.789283+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11044",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RNASET2 as ready",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:13:16.779868+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11044",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnaset2 has been classified as Green List (High Evidence).",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:13:08.217832+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11044",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RNASET2 were changed from to Leukoencephalopathy, cystic, without megalencephaly MIM#612951",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:12:47.041603+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11043",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RNASET2 were set to ",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:12:26.520459+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11042",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Mode of inheritance for gene: RNASET2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "RNASET2",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:11:46.427053+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11041",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: C17orf53 as ready",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:11:46.417989+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11041",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: c17orf53 has been classified as Amber List (Moderate Evidence).",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:11:19.614250+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11041",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: C17orf53 as Amber List (moderate evidence)",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:11:19.602490+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11041",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: c17orf53 has been classified as Amber List (Moderate Evidence).",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:11:02.206730+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11040",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "gene: C17orf53 was added\ngene: C17orf53 was added to Mendeliome. Sources: Expert Review\nMode of inheritance for gene: C17orf53 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: C17orf53 were set to 34707299; 31467087\nPhenotypes for gene: C17orf53 were set to Primary ovarian insufficiency\nReview for gene: C17orf53 was set to AMBER\nAdded comment: PMID: 34707299. Homozygous LOF variant in individual with primary ovarian insufficiency PMID: 31467087. Mice with targeted mutations in Hrob are infertile due to depletion of germ cells. \nSources: Expert Review",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:09:13.802125+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.287",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: C17orf53 as ready",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:09:13.790826+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.287",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: c17orf53 has been classified as Amber List (Moderate Evidence).",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:08:40.107875+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.287",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: C17orf53 as Amber List (moderate evidence)",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:08:40.096512+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.287",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: c17orf53 has been classified as Amber List (Moderate Evidence).",
"entity_name": "C17orf53",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:08:16.097975+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3745",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RNASEH2C as ready",
"entity_name": "RNASEH2C",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:08:16.080387+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3745",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnaseh2c has been classified as Green List (High Evidence).",
"entity_name": "RNASEH2C",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:08:12.154349+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3745",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RNASEH2C were changed from AICARDI-GOUTIERES SYNDROME 3 to Aicardi-Goutieres syndrome 3 (MIM# 610329), AR",
"entity_name": "RNASEH2C",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:07:58.228708+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3744",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RNASEH2C were set to ",
"entity_name": "RNASEH2C",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:06:48.694989+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.700",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TFAM were set to 27448789; 29021295; 9500544",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:06:20.030599+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.699",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TFAM as Green List (high evidence)",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:06:20.007682+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.699",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tfam has been classified as Green List (High Evidence).",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:06:16.350705+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11039",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TFAM were changed from Mitochondrial DNA depletion syndrome 15 (hepatocerebral type)\tMIM#617156 to Mitochondrial DNA depletion syndrome 15 (hepatocerebral type)\tMIM#617156; Perrault syndrome",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:05:37.320509+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.699",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TFAM as Green List (high evidence)",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:05:37.310005+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.699",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tfam has been classified as Green List (High Evidence).",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:05:29.054050+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11038",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TFAM were set to 27448789; 29021295; 9500544",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:05:04.628108+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11037",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TFAM as Green List (high evidence)",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:05:04.618983+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11037",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tfam has been classified as Green List (High Evidence).",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:04:47.028303+11:00",
"panel_name": "Mendeliome",
"panel_id": 137,
"panel_version": "0.11036",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: TFAM: Added comment: PMID: 32399598. Homozygous missense variant predicted pathogenic in patient presenting with Perrault syndrome and intellectual disability\r\n\r\nPMID: 34647195. Same homozygous missense variant in two sisters with premature ovarian insufficiency +/- seizures and their brother with seizures + intellectual disability. Patient fibroblasts have mtDNA depletion\r\n\r\nPMID: 34647195. Zebrafish model with in-frame deletion has ovarian dysgenesis and mtDNA depletion; Changed rating: GREEN; Changed publications: 27448789, 29021295, 9500544, 32399598, 34647195, 34647195; Changed phenotypes: Mitochondrial DNA depletion syndrome 15 (hepatocerebral type) MIM#617156, Perrault syndrome",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T20:04:01.239485+11:00",
"panel_name": "Mitochondrial disease",
"panel_id": 203,
"panel_version": "0.698",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: TFAM: Rating: GREEN; Mode of pathogenicity: None; Publications: 32399598, 34647195, 34647195; Phenotypes: Perrault syndrome; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:54:56.104826+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: TFAM as ready",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:54:56.093001+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tfam has been classified as Green List (High Evidence).",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:54:53.924583+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.286",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: TFAM were changed from to Perrault syndrome; primary ovarian insufficiency +/- seizures/intellectual disability/hearing loss",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:54:46.366267+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.285",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: TFAM were set to PMID: 34647195",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:54:35.745914+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.284",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: TFAM as Green List (high evidence)",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:54:35.734401+11:00",
"panel_name": "Primary Ovarian Insufficiency_Premature Ovarian Failure",
"panel_id": 3166,
"panel_version": "0.284",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: tfam has been classified as Green List (High Evidence).",
"entity_name": "TFAM",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:53:44.123148+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3743",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NKX2-1 as ready",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:53:44.112346+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3743",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nkx2-1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:53:38.900646+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3743",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NKX2-1 as Amber List (moderate evidence)",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:53:38.889327+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3743",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nkx2-1 has been classified as Amber List (Moderate Evidence).",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:53:26.559639+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3742",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: NKX2-1: Changed rating: AMBER",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:53:07.957795+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3742",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: NKX2-1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "NKX2-1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:52:09.764679+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3742",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IYD as ready",
"entity_name": "IYD",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:52:09.753183+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3742",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: iyd has been classified as Red List (Low Evidence).",
"entity_name": "IYD",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:52:04.038445+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3742",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: IYD as Red List (low evidence)",
"entity_name": "IYD",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:52:04.020054+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3742",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: iyd has been classified as Red List (Low Evidence).",
"entity_name": "IYD",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:51:47.829707+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3741",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: IYD: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "IYD",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:51:16.461433+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3741",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: IRS4 as ready",
"entity_name": "IRS4",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:51:16.449730+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3741",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: irs4 has been classified as Red List (Low Evidence).",
"entity_name": "IRS4",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:51:10.463428+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3741",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: IRS4 as Red List (low evidence)",
"entity_name": "IRS4",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:51:10.450116+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3741",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: irs4 has been classified as Red List (Low Evidence).",
"entity_name": "IRS4",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:50:59.004137+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3740",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "edited their review of gene: IRS4: Changed rating: RED",
"entity_name": "IRS4",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:50:52.192540+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3740",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: IRS4: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "IRS4",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:50:22.680145+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3740",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DUOXA2 as ready",
"entity_name": "DUOXA2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:50:22.670324+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3740",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: duoxa2 has been classified as Red List (Low Evidence).",
"entity_name": "DUOXA2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:50:17.788173+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3740",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DUOXA2 as Red List (low evidence)",
"entity_name": "DUOXA2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:50:17.776304+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3740",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: duoxa2 has been classified as Red List (Low Evidence).",
"entity_name": "DUOXA2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:50:06.675799+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3739",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: DUOXA2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "DUOXA2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:49:38.993014+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3739",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DUOXA1 as ready",
"entity_name": "DUOXA1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:49:38.981494+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3739",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: duoxa1 has been classified as Red List (Low Evidence).",
"entity_name": "DUOXA1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:49:32.458070+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3739",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DUOXA1 as Red List (low evidence)",
"entity_name": "DUOXA1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:49:32.447651+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3739",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: duoxa1 has been classified as Red List (Low Evidence).",
"entity_name": "DUOXA1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:49:21.391080+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3738",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: DUOXA1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "DUOXA1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:48:11.228659+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3738",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DUOX2 as ready",
"entity_name": "DUOX2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:48:11.213425+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3738",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: duox2 has been classified as Red List (Low Evidence).",
"entity_name": "DUOX2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:48:05.371879+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3738",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DUOX2 as Red List (low evidence)",
"entity_name": "DUOX2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:48:05.358578+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3738",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: duox2 has been classified as Red List (Low Evidence).",
"entity_name": "DUOX2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:47:54.042770+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3737",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: DUOX2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "DUOX2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:47:27.096438+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3737",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: DUOX1 as ready",
"entity_name": "DUOX1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:47:27.086975+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3737",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: duox1 has been classified as Red List (Low Evidence).",
"entity_name": "DUOX1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:47:21.825179+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3737",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: DUOX1 as Red List (low evidence)",
"entity_name": "DUOX1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:47:21.810214+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3737",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: duox1 has been classified as Red List (Low Evidence).",
"entity_name": "DUOX1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:47:08.856979+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: DUOX1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None",
"entity_name": "DUOX1",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:46:29.621171+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RNASEH2B as ready",
"entity_name": "RNASEH2B",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:46:29.611251+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnaseh2b has been classified as Green List (High Evidence).",
"entity_name": "RNASEH2B",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:46:21.509073+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3736",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RNASEH2B were changed from AICARDI-GOUTIERES SYNDROME 2 to Aicardi-Goutieres syndrome 2, MIM# 610181",
"entity_name": "RNASEH2B",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:45:55.088360+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3735",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RNASEH2B were set to ",
"entity_name": "RNASEH2B",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:45:31.305878+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3734",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: RNASEH2A as ready",
"entity_name": "RNASEH2A",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:45:31.294732+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3734",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: rnaseh2a has been classified as Green List (High Evidence).",
"entity_name": "RNASEH2A",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:45:27.228076+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3734",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Phenotypes for gene: RNASEH2A were changed from AICARDI-GOUTIERES SYNDROME 4 to Aicardi-Goutieres syndrome 4 MIM#610333",
"entity_name": "RNASEH2A",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:45:15.186719+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3733",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Publications for gene: RNASEH2A were set to ",
"entity_name": "RNASEH2A",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:44:47.791934+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3732",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: CDCA8 as ready",
"entity_name": "CDCA8",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:44:47.782047+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3732",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cdca8 has been classified as Red List (Low Evidence).",
"entity_name": "CDCA8",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:44:41.453804+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3732",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: CDCA8 as Red List (low evidence)",
"entity_name": "CDCA8",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:44:41.437501+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3732",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: cdca8 has been classified as Red List (Low Evidence).",
"entity_name": "CDCA8",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:44:29.690713+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3731",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "reviewed gene: CDCA8: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Congenital hypothyroidism, thyroid dysgenesis, no OMIM #; Mode of inheritance: None",
"entity_name": "CDCA8",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:43:32.422901+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3731",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NPRL3 as ready",
"entity_name": "NPRL3",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:43:32.404466+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3731",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nprl3 has been classified as Green List (High Evidence).",
"entity_name": "NPRL3",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:43:26.780225+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3731",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NPRL3 as Green List (high evidence)",
"entity_name": "NPRL3",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:43:26.768322+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3731",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nprl3 has been classified as Green List (High Evidence).",
"entity_name": "NPRL3",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:43:03.660418+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3730",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Marked gene: NPRL2 as ready",
"entity_name": "NPRL2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:43:03.647726+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3730",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Gene: nprl2 has been classified as Green List (High Evidence).",
"entity_name": "NPRL2",
"entity_type": "gene"
},
{
"created": "2022-02-21T18:42:29.707816+11:00",
"panel_name": "Fetal anomalies",
"panel_id": 3763,
"panel_version": "0.3730",
"user_name": "Zornitza Stark",
"item_type": "entity",
"text": "Classified gene: NPRL2 as Green List (high evidence)",
"entity_name": "NPRL2",
"entity_type": "gene"
}
]
}