{"count":220313,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1361","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1359","results":[{"created":"2021-04-07T20:57:42.204592+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.37","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: EDNRA as ready","entity_name":"EDNRA","entity_type":"gene"},{"created":"2021-04-07T20:57:42.192636+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.37","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ednra has been classified as Green List (High Evidence).","entity_name":"EDNRA","entity_type":"gene"},{"created":"2021-04-07T20:57:36.971518+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.37","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: EDNRA were changed from  to Mandibulofacial dysostosis with alopecia, MIM# 616367","entity_name":"EDNRA","entity_type":"gene"},{"created":"2021-04-07T20:57:07.094941+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.36","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: EDNRA were set to ","entity_name":"EDNRA","entity_type":"gene"},{"created":"2021-04-07T20:56:43.638785+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.35","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: EDNRA was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"EDNRA","entity_type":"gene"},{"created":"2021-04-07T20:56:12.636622+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.34","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: EDNRA: Rating: GREEN; Mode of pathogenicity: None; Publications: 25772936, 27671791; Phenotypes: Mandibulofacial dysostosis with alopecia, MIM# 616367; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"EDNRA","entity_type":"gene"},{"created":"2021-04-07T20:52:41.531911+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7048","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: EDN1 as ready","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:52:41.521497+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7048","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: edn1 has been classified as Amber List (Moderate Evidence).","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:52:30.652798+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7048","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: EDN1 were changed from  to Auriculocondylar syndrome 3, MIM# 615706","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:52:06.745750+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7047","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: EDN1 were set to ","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:51:46.255505+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7046","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: EDN1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:51:25.018512+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7045","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: EDN1 as Amber List (moderate evidence)","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:51:25.004938+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7045","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: edn1 has been classified as Amber List (Moderate Evidence).","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:51:04.552821+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7044","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: EDN1: Rating: AMBER; Mode of pathogenicity: None; Publications: 23315542, 23913798, 24268655; Phenotypes: Auriculocondylar syndrome 3, MIM# 615706; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:50:56.386114+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.34","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: EDN1 were changed from  to Auriculocondylar syndrome 3, MIM# 615706","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:50:12.688508+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: EDN1 as ready","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:50:12.678138+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: edn1 has been classified as Amber List (Moderate Evidence).","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:50:00.890663+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: EDN1 were changed from  to Auriculocondylar syndrome 3, MIM# 615706","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:49:29.737447+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.27","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: EDN1 were set to ","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:48:07.346160+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: EDN1 was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:47:42.775996+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: EDN1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:47:27.689680+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: EDN1 as Amber List (moderate evidence)","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:47:27.679027+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: edn1 has been classified as Amber List (Moderate Evidence).","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:47:24.719241+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.33","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: EDN1 were set to 23315542; 23913798; 24268655","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:47:09.697963+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.33","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: EDN1 were set to ","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:46:53.965418+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.24","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: EDN1: Rating: AMBER; Mode of pathogenicity: None; Publications: 23315542, 23913798, 24268655; Phenotypes: Auriculocondylar syndrome 3, MIM# 615706; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:46:37.964395+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.32","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: EDN1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:46:01.936166+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.31","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: EDN1 as Amber List (moderate evidence)","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:46:01.926125+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.31","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: edn1 has been classified as Amber List (Moderate Evidence).","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:45:37.829444+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.30","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: EDN1: Rating: AMBER; Mode of pathogenicity: None; Publications: 23315542, 23913798, 24268655; Phenotypes: Auriculocondylar syndrome 3, MIM# 615706; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"EDN1","entity_type":"gene"},{"created":"2021-04-07T20:40:48.763278+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.30","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2021-04-07T20:03:49.519074+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3603","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CLN5 as ready","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:03:49.509152+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3603","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cln5 has been classified as Green List (High Evidence).","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:03:44.565782+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3603","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLN5 were changed from  to Ceroid lipofuscinosis, neuronal, 5, MIM# 256731; MONDO:0009745","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:03:10.011052+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3602","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CLN5 were set to ","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:02:45.412623+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3601","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CLN5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:02:16.633098+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3600","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CLN5: Rating: GREEN; Mode of pathogenicity: None; Publications: 20157158; Phenotypes: Ceroid lipofuscinosis, neuronal, 5, MIM# 256731, MONDO:0009745; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:01:30.178650+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7044","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CLN5 as ready","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:01:30.168708+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7044","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cln5 has been classified as Green List (High Evidence).","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:01:12.046179+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7044","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLN5 were changed from  to Ceroid lipofuscinosis, neuronal, 5, MIM# 256731; MONDO:0009745","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:00:53.842834+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7043","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CLN5 were set to ","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:00:36.332789+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7042","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CLN5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T20:00:17.048686+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7041","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CLN5: Rating: GREEN; Mode of pathogenicity: None; Publications: 20157158; Phenotypes: Ceroid lipofuscinosis, neuronal, 5, MIM# 256731, MONDO:0009745; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T19:59:28.716550+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.83","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CLN5 as ready","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T19:59:28.706375+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.83","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cln5 has been classified as Green List (High Evidence).","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T19:59:21.623486+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.83","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLN5 were changed from  to Ceroid lipofuscinosis, neuronal, 5, MIM# 256731; MONDO:0009745","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T19:58:50.974093+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.82","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CLN5 were set to ","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T19:58:28.541252+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.81","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CLN5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T19:57:48.122905+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.80","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CLN5: Rating: GREEN; Mode of pathogenicity: None; Publications: 20157158; Phenotypes: Ceroid lipofuscinosis, neuronal, 5, MIM# 256731, MONDO:0009745; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN5","entity_type":"gene"},{"created":"2021-04-07T19:05:06.517490+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7041","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CLN3 as ready","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:05:06.507487+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7041","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cln3 has been classified as Green List (High Evidence).","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:04:58.853690+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7041","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLN3 were changed from  to Ceroid lipofuscinosis, neuronal, 3, MIM# 204200; MONDO:0008767","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:04:40.754183+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7040","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CLN3 were set to ","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:04:23.275589+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7039","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CLN3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:04:03.668177+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7038","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CLN3: Rating: GREEN; Mode of pathogenicity: None; Publications: 7553855; Phenotypes: Ceroid lipofuscinosis, neuronal, 3, MIM# 204200, MONDO:0008767; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:03:10.707052+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.80","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLN3 were changed from Ceroid lipofuscinosis, neuronal, 3, MIM# 204200 to Ceroid lipofuscinosis, neuronal, 3, MIM# 204200; MONDO:0008767","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:02:13.207334+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.79","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CLN3 as ready","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:02:13.196414+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.79","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cln3 has been classified as Green List (High Evidence).","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:02:10.439780+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.79","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLN3 were changed from  to Ceroid lipofuscinosis, neuronal, 3, MIM# 204200","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:01:46.978861+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.78","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CLN3 were set to ","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:01:27.729080+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.77","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CLN3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T19:00:56.372438+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.76","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CLN3: Rating: GREEN; Mode of pathogenicity: None; Publications: 7553855; Phenotypes: Ceroid lipofuscinosis, neuronal, 3, MIM# 204200; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLN3","entity_type":"gene"},{"created":"2021-04-07T18:58:41.433969+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.76","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ARSB as ready","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:58:41.418393+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.76","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: arsb has been classified as Green List (High Evidence).","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:58:36.201480+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3600","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ARSB as ready","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:58:36.190178+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3600","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: arsb has been classified as Green List (High Evidence).","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:58:32.216740+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3600","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ARSB were changed from  to Mucopolysaccharidosis type VI (Maroteaux-Lamy), MIM# 253200; MONDO:0009661","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:58:04.242064+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3599","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ARSB were set to ","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:57:41.726782+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3598","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ARSB was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:57:08.249828+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3597","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ARSB: Rating: GREEN; Mode of pathogenicity: None; Publications: 11668612; Phenotypes: Mucopolysaccharidosis type VI (Maroteaux-Lamy), MIM# 253200, MONDO:0009661; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:56:52.504355+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.76","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ARSB were changed from  to Mucopolysaccharidosis type VI (Maroteaux-Lamy), MIM# 253200; MONDO:0009661","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:56:12.703814+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7038","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ARSB as ready","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:56:12.694012+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7038","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: arsb has been classified as Green List (High Evidence).","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:56:05.546785+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7038","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ARSB were changed from  to Mucopolysaccharidosis type VI (Maroteaux-Lamy), MIM# 253200; MONDO:0009661","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:55:48.641665+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7037","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ARSB were set to ","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:55:33.388489+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7036","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ARSB was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:55:15.111085+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7035","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ARSB: Rating: GREEN; Mode of pathogenicity: None; Publications: 11668612; Phenotypes: Mucopolysaccharidosis type VI (Maroteaux-Lamy), MIM# 253200, MONDO:0009661; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:55:07.587763+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.75","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ARSB were set to ","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:54:33.322977+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.74","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ARSB was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:53:58.776839+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.73","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ARSB: Rating: GREEN; Mode of pathogenicity: None; Publications: 11668612; Phenotypes: Mucopolysaccharidosis type VI (Maroteaux-Lamy), MIM# 253200, MONDO:0009661; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ARSB","entity_type":"gene"},{"created":"2021-04-07T18:52:18.954265+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.73","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ARSA as ready","entity_name":"ARSA","entity_type":"gene"},{"created":"2021-04-07T18:52:18.943533+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.73","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: arsa has been classified as Green List (High Evidence).","entity_name":"ARSA","entity_type":"gene"},{"created":"2021-04-07T18:52:14.688836+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.73","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ARSA were changed from  to Metachromatic leukodystrophy, MIM# 250100; MONDO:0009591","entity_name":"ARSA","entity_type":"gene"},{"created":"2021-04-07T18:51:39.569533+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.72","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ARSA was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ARSA","entity_type":"gene"},{"created":"2021-04-07T18:51:08.017196+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.71","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ARSA: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Metachromatic leukodystrophy, MIM# 250100, MONDO:0009591; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ARSA","entity_type":"gene"},{"created":"2021-04-07T18:05:41.955423+10:00","panel_name":"Macrocephaly_Megalencephaly","panel_id":135,"panel_version":"0.62","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: AGA as ready","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:05:41.943126+10:00","panel_name":"Macrocephaly_Megalencephaly","panel_id":135,"panel_version":"0.62","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: aga has been classified as Green List (High Evidence).","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:05:38.990194+10:00","panel_name":"Macrocephaly_Megalencephaly","panel_id":135,"panel_version":"0.62","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: AGA were changed from  to Aspartylglucosaminuria, MIM# 208400; MONDO:0008830","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:05:15.649349+10:00","panel_name":"Macrocephaly_Megalencephaly","panel_id":135,"panel_version":"0.61","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: AGA were set to ","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:04:30.154270+10:00","panel_name":"Macrocephaly_Megalencephaly","panel_id":135,"panel_version":"0.60","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: AGA was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:04:05.048418+10:00","panel_name":"Macrocephaly_Megalencephaly","panel_id":135,"panel_version":"0.59","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: AGA: Rating: GREEN; Mode of pathogenicity: None; Publications: 1703489, 1904874, 8064811, 8946839; Phenotypes: Aspartylglucosaminuria, MIM# 208400, MONDO:0008830; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:03:18.375436+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7035","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: AGA as ready","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:03:18.365602+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7035","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: aga has been classified as Green List (High Evidence).","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:03:10.936611+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7035","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: AGA were changed from  to Aspartylglucosaminuria, MIM# 208400; MONDO:0008830","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:02:51.077782+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7034","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: AGA were set to ","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:02:33.569796+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7033","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: AGA was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:02:14.521156+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.7032","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: AGA: Added comment: Aspartylglucosaminuria (AGU) is a severe autosomal recessive lysosomal storage disorder that involves the central nervous system and causes skeletal abnormalities as well as connective tissue lesions. The most characteristic feature is progressive mental retardation. Multiple families and mouse model.; Changed publications: 1703489, 1904874, 8064811, 8946839; Changed phenotypes: Aspartylglucosaminuria, MIM# 208400, MONDO:0008830","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:01:27.229547+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.71","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: AGA were changed from Aspartylglucosaminuria, MIM# 208400 to Aspartylglucosaminuria, MIM# 208400; MONDO:0008830","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:00:35.010563+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: AGA as ready","entity_name":"AGA","entity_type":"gene"},{"created":"2021-04-07T18:00:34.991725+10:00","panel_name":"Lysosomal Storage Disorder","panel_id":181,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: aga has been classified as Green List (High Evidence).","entity_name":"AGA","entity_type":"gene"}]}