{"count":220293,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1366","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1364","results":[{"created":"2021-04-01T18:35:01.234533+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.611","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SLC25A19 were set to ","entity_name":"SLC25A19","entity_type":"gene"},{"created":"2021-04-01T18:34:15.174902+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.610","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SLC25A19 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLC25A19","entity_type":"gene"},{"created":"2021-04-01T18:33:35.649584+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.609","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SLC25A19 as Amber List (moderate evidence)","entity_name":"SLC25A19","entity_type":"gene"},{"created":"2021-04-01T18:33:35.636615+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.609","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc25a19 has been classified as Amber List (Moderate Evidence).","entity_name":"SLC25A19","entity_type":"gene"},{"created":"2021-04-01T18:33:13.958567+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.608","user_name":"Zornitza Stark","item_type":"entity","text":"Tag founder tag was added to gene: SLC25A19.","entity_name":"SLC25A19","entity_type":"gene"},{"created":"2021-04-01T18:33:05.305813+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.608","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SLC25A19: Rating: AMBER; Mode of pathogenicity: None; Publications: 12185364; Phenotypes: Microcephaly, Amish type, MIM# 607196; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLC25A19","entity_type":"gene"},{"created":"2021-04-01T18:28:37.636189+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3582","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RTTN as ready","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T18:28:37.620419+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3582","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rttn has been classified as Green List (High Evidence).","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T18:28:32.781754+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3582","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RTTN were changed from  to Microcephaly, short stature, and polymicrogyria with seizures, MIM# 614833; Microcephalic primordial dwarfism due to RTTN deficiency MONDO:0018764","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T18:28:00.179209+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3581","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RTTN were set to ","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T18:27:34.461553+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3580","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RTTN was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T18:27:07.705967+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3579","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RTTN: Rating: GREEN; Mode of pathogenicity: None; Publications: 22939636, 26608784, 26940245, 30121372, 29967526, 30927481, 30121372; Phenotypes: Microcephaly, short stature, and polymicrogyria with seizures, MIM# 614833, Microcephalic primordial dwarfism due to RTTN deficiency MONDO:0018764; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T17:59:32.550913+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.608","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RTTN as ready","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T17:59:32.540844+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.608","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rttn has been classified as Green List (High Evidence).","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T17:57:48.518311+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.608","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RTTN were changed from  to Microcephaly, short stature, and polymicrogyria with seizures, MIM# 614833; Microcephalic primordial dwarfism due to RTTN deficiency MONDO:0018764","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T17:34:32.932830+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.607","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RTTN were set to ","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T17:34:02.681940+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.606","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RTTN was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T17:33:34.440625+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.605","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: RTTN: Changed phenotypes: Microcephaly, short stature, and polymicrogyria with seizures, MIM# 614833, Microcephalic primordial dwarfism due to RTTN deficiency MONDO:0018764","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T17:32:42.140429+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.605","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RTTN: Rating: GREEN; Mode of pathogenicity: None; Publications: 22939636, 26608784, 26940245, 30121372, 29967526, 30927481, 30121372; Phenotypes: Microcephaly, short stature, and polymicrogyria with seizures, MIM# 614833; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RTTN","entity_type":"gene"},{"created":"2021-04-01T17:29:14.373380+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.605","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RBBP8 as ready","entity_name":"RBBP8","entity_type":"gene"},{"created":"2021-04-01T17:29:14.363178+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.605","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rbbp8 has been classified as Green List (High Evidence).","entity_name":"RBBP8","entity_type":"gene"},{"created":"2021-04-01T17:29:12.135981+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.605","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RBBP8 were changed from  to Jawad syndrome, MIM# 251255; Seckel syndrome 2, MIM# 606744","entity_name":"RBBP8","entity_type":"gene"},{"created":"2021-04-01T17:28:47.603460+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.604","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RBBP8 were set to ","entity_name":"RBBP8","entity_type":"gene"},{"created":"2021-04-01T17:28:19.800419+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.603","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RBBP8 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RBBP8","entity_type":"gene"},{"created":"2021-04-01T17:27:51.227152+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.602","user_name":"Zornitza Stark","item_type":"entity","text":"changed review comment from: Well established gene-disease association, microcephaly is a feature of both conditions.; to: Microcephaly is a feature of both conditions, which overlap phenotypically.","entity_name":"RBBP8","entity_type":"gene"},{"created":"2021-04-01T17:27:23.089122+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.602","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: RBBP8: Changed publications: 26333564, 24440292, 21998596, 24389050","entity_name":"RBBP8","entity_type":"gene"},{"created":"2021-04-01T17:24:19.379220+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.602","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RBBP8: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Jawad syndrome, MIM# 251255, Seckel syndrome 2, MIM# 606744; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RBBP8","entity_type":"gene"},{"created":"2021-04-01T17:20:40.129076+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.602","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PQBP1 as ready","entity_name":"PQBP1","entity_type":"gene"},{"created":"2021-04-01T17:20:40.118677+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.602","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pqbp1 has been classified as Green List (High Evidence).","entity_name":"PQBP1","entity_type":"gene"},{"created":"2021-04-01T17:20:37.882303+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.602","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PQBP1 were changed from  to Renpenning syndrome, MIM# 309500","entity_name":"PQBP1","entity_type":"gene"},{"created":"2021-04-01T17:20:09.319813+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.601","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PQBP1 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"PQBP1","entity_type":"gene"},{"created":"2021-04-01T17:19:32.893469+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.600","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PQBP1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Renpenning syndrome, MIM# 309500; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"PQBP1","entity_type":"gene"},{"created":"2021-04-01T16:40:13.251663+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.600","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PNKP were changed from Microcephaly, seizures, and developmental delay, MIM# 613402 to Microcephaly, seizures, and developmental delay, MIM# 613402; MONDO:0013254","entity_name":"PNKP","entity_type":"gene"},{"created":"2021-04-01T16:39:16.654745+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.599","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PNKP as ready","entity_name":"PNKP","entity_type":"gene"},{"created":"2021-04-01T16:39:16.641826+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.599","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pnkp has been classified as Green List (High Evidence).","entity_name":"PNKP","entity_type":"gene"},{"created":"2021-04-01T16:39:13.959569+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.599","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PNKP were changed from  to Microcephaly, seizures, and developmental delay, MIM# 613402","entity_name":"PNKP","entity_type":"gene"},{"created":"2021-04-01T16:38:43.768690+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.598","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PNKP were set to ","entity_name":"PNKP","entity_type":"gene"},{"created":"2021-04-01T16:38:11.118479+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.597","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PNKP was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PNKP","entity_type":"gene"},{"created":"2021-04-01T16:37:46.264196+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.596","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PNKP: Rating: GREEN; Mode of pathogenicity: None; Publications: 20118933, 23224214, 32980744, 31707899; Phenotypes: Microcephaly, seizures, and developmental delay, MIM# 613402; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PNKP","entity_type":"gene"},{"created":"2021-04-01T15:36:15.118464+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3579","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: BRD4 as Red List (low evidence)","entity_name":"BRD4","entity_type":"gene"},{"created":"2021-04-01T15:36:15.109064+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3579","user_name":"Chirag Patel","item_type":"entity","text":"Gene: brd4 has been classified as Red List (Low Evidence).","entity_name":"BRD4","entity_type":"gene"},{"created":"2021-04-01T15:35:09.780462+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3578","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: BRD4: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None","entity_name":"BRD4","entity_type":"gene"},{"created":"2021-04-01T13:03:56.114381+11:00","panel_name":"Craniosynostosis","panel_id":93,"panel_version":"1.17","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: FGF9 were set to ","entity_name":"FGF9","entity_type":"gene"},{"created":"2021-04-01T13:03:19.823057+11:00","panel_name":"Craniosynostosis","panel_id":93,"panel_version":"1.16","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: FGF9 as Green List (high evidence)","entity_name":"FGF9","entity_type":"gene"},{"created":"2021-04-01T13:03:19.814087+11:00","panel_name":"Craniosynostosis","panel_id":93,"panel_version":"1.16","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fgf9 has been classified as Green List (High Evidence).","entity_name":"FGF9","entity_type":"gene"},{"created":"2021-04-01T10:44:05.719697+11:00","panel_name":"Craniosynostosis","panel_id":93,"panel_version":"1.15","user_name":"Chris Richmond","item_type":"entity","text":"reviewed gene: FGF9: Rating: GREEN; Mode of pathogenicity: None; Publications: 19589401, 28730625, 19219044; Phenotypes: Multiple synostoses syndrome 3 (612961); Mode of inheritance: None","entity_name":"FGF9","entity_type":"gene"},{"created":"2021-03-31T21:05:22.145714+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.274","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PCNT as ready","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T21:05:22.136428+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.274","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pcnt has been classified as Red List (Low Evidence).","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T21:05:18.918844+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.274","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PCNT were changed from  to Microcephalic osteodysplastic primordial dwarfism, type II, MIM# 210720; MONDO:0008872","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T21:04:55.461929+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.273","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PCNT was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T21:04:34.074501+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.272","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: PCNT as Red List (low evidence)","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T21:04:34.064818+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.272","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pcnt has been classified as Red List (Low Evidence).","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T21:04:09.951886+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.271","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PCNT: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Microcephalic osteodysplastic primordial dwarfism, type II, MIM# 210720, MONDO:0008872; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:58:33.276988+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6972","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PCNT as ready","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:58:33.267327+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6972","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pcnt has been classified as Green List (High Evidence).","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:58:26.280841+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6972","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PCNT were changed from  to Microcephalic osteodysplastic primordial dwarfism, type II, MIM# 210720; MONDO:0008872","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:58:07.371626+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6971","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PCNT were set to ","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:57:47.589445+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6970","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PCNT was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:57:31.019328+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6969","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PCNT: Rating: GREEN; Mode of pathogenicity: None; Publications: 18174396, 12210304, 30922925, 33460028, 32557621, 32267100; Phenotypes: Microcephalic osteodysplastic primordial dwarfism, type II, MIM# 210720, MONDO:0008872; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:56:43.218999+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.596","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PCNT as ready","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:56:43.209487+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.596","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pcnt has been classified as Green List (High Evidence).","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:56:40.737020+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.596","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PCNT were changed from  to Microcephalic osteodysplastic primordial dwarfism, type II, MIM# 210720; MONDO:0008872","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:56:18.319289+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.595","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PCNT were set to ","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:55:49.328809+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.594","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PCNT was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:55:18.461706+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.593","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PCNT: Rating: GREEN; Mode of pathogenicity: None; Publications: 18174396, 12210304, 30922925, 33460028, 32557621, 32267100; Phenotypes: Microcephalic osteodysplastic primordial dwarfism, type II, MIM# 210720, MONDO:0008872; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCNT","entity_type":"gene"},{"created":"2021-03-31T20:37:25.914260+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.593","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ORC6 as ready","entity_name":"ORC6","entity_type":"gene"},{"created":"2021-03-31T20:37:25.898917+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.593","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: orc6 has been classified as Green List (High Evidence).","entity_name":"ORC6","entity_type":"gene"},{"created":"2021-03-31T20:37:23.190118+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.593","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ORC6 were changed from  to Meier-Gorlin syndrome 3, MIM# 613803","entity_name":"ORC6","entity_type":"gene"},{"created":"2021-03-31T20:36:59.292800+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.592","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ORC6 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ORC6","entity_type":"gene"},{"created":"2021-03-31T20:36:29.786210+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.591","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ORC6: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Meier-Gorlin syndrome 3, MIM# 613803; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ORC6","entity_type":"gene"},{"created":"2021-03-31T17:45:59.216234+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.591","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ORC4 as ready","entity_name":"ORC4","entity_type":"gene"},{"created":"2021-03-31T17:45:59.206375+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.591","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: orc4 has been classified as Green List (High Evidence).","entity_name":"ORC4","entity_type":"gene"},{"created":"2021-03-31T17:42:49.757904+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.591","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ORC4 were changed from  to Meier-Gorlin syndrome 2, MIM# 613800; MONDO:0013428","entity_name":"ORC4","entity_type":"gene"},{"created":"2021-03-31T17:41:23.715029+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.590","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ORC4 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ORC4","entity_type":"gene"},{"created":"2021-03-31T17:40:59.116131+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.589","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ORC4: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Meier-Gorlin syndrome 2, MIM# 613800, MONDO:0013428; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ORC4","entity_type":"gene"},{"created":"2021-03-31T16:56:25.001202+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.589","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ORC1 as ready","entity_name":"ORC1","entity_type":"gene"},{"created":"2021-03-31T16:56:24.991062+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.589","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: orc1 has been classified as Green List (High Evidence).","entity_name":"ORC1","entity_type":"gene"},{"created":"2021-03-31T16:56:09.866866+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.589","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ORC1 were changed from  to Meier-Gorlin syndrome 1, MIM# 224690; MONDO:0009143","entity_name":"ORC1","entity_type":"gene"},{"created":"2021-03-31T16:55:31.280812+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.588","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ORC1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ORC1","entity_type":"gene"},{"created":"2021-03-31T16:55:00.719007+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.587","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ORC1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Meier-Gorlin syndrome 1, MIM# 224690; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ORC1","entity_type":"gene"},{"created":"2021-03-31T16:53:37.278959+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6969","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NHEJ1 as ready","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:53:37.268926+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6969","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nhej1 has been classified as Green List (High Evidence).","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:53:30.365841+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6969","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NHEJ1 were changed from  to Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation, MIM# 611291; Cernunnos-XLF deficiency MONDO:0012650","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:53:11.451161+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6968","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NHEJ1 were set to ","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:52:30.733734+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6967","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NHEJ1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:50:55.303671+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6966","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NHEJ1: Rating: GREEN; Mode of pathogenicity: None; Publications: 30898087, 30666249, 28741180, 25288157, 24511403, 21721379, 21535335; Phenotypes: Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation, MIM# 611291, Cernunnos-XLF deficiency MONDO:0012650; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:49:48.465333+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.587","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NHEJ1 were changed from Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation, MIM# 611291 to Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation, MIM# 611291; Cernunnos-XLF deficiency MONDO:0012650","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:48:56.684613+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.586","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: NHEJ1: Changed phenotypes: Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation, MIM# 611291, Cernunnos-XLF deficiency MONDO:0012650","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:47:21.006009+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.586","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NHEJ1 as ready","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:47:20.995118+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.586","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nhej1 has been classified as Green List (High Evidence).","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:47:15.233387+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.586","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NHEJ1 were changed from  to Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation, MIM# 611291","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:46:57.398665+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.585","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NHEJ1 were set to ","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:45:49.597840+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.584","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NHEJ1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:45:17.292813+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.583","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NHEJ1: Rating: GREEN; Mode of pathogenicity: None; Publications: 30898087, 30666249, 28741180, 25288157, 24511403, 21721379, 21535335; Phenotypes: Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation, MIM# 611291; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"NHEJ1","entity_type":"gene"},{"created":"2021-03-31T16:37:56.412948+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3578","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDE1 as ready","entity_name":"NDE1","entity_type":"gene"},{"created":"2021-03-31T16:37:56.402224+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3578","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nde1 has been classified as Green List (High Evidence).","entity_name":"NDE1","entity_type":"gene"},{"created":"2021-03-31T16:37:52.018484+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3578","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDE1 were changed from  to Lissencephaly 4 (with microcephaly), MIM# 614019; MONDO:0013527; Microhydranencephaly, MIM# 605013; MONDO:0011504","entity_name":"NDE1","entity_type":"gene"},{"created":"2021-03-31T16:37:19.599550+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3577","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDE1 were set to ","entity_name":"NDE1","entity_type":"gene"},{"created":"2021-03-31T16:36:48.267402+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3576","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDE1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NDE1","entity_type":"gene"},{"created":"2021-03-31T16:36:15.723945+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3575","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NDE1: Rating: GREEN; Mode of pathogenicity: None; Publications: 21529752, 21529751, 30637988, 15473967; Phenotypes: Lissencephaly 4 (with microcephaly), MIM# 614019, MONDO:0013527, Microhydranencephaly, MIM# 605013, MONDO:0011504; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"NDE1","entity_type":"gene"}]}