{"count":220212,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1406","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1404","results":[{"created":"2021-02-18T17:29:10.550948+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"gene: PIK3R2 was added\ngene: PIK3R2 was added to Mosaic skin disorders. Sources: Literature\nMode of inheritance for gene: PIK3R2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: PIK3R2 were set to PMID: 22729224\nReview for gene: PIK3R2 was set to GREEN\nAdded comment: Sources: Literature","entity_name":"PIK3R2","entity_type":"gene"},{"created":"2021-02-18T17:24:30.069215+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"gene: TSC2 was added\ngene: TSC2 was added to Mosaic skin disorders. Sources: Literature,Expert Review\nMode of inheritance for gene: TSC2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: TSC2 were set to PMID: 26540169\nReview for gene: TSC2 was set to GREEN\nAdded comment: Sources: Literature, Expert Review","entity_name":"TSC2","entity_type":"gene"},{"created":"2021-02-18T17:23:59.262311+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"gene: TSC1 was added\ngene: TSC1 was added to Mosaic skin disorders. Sources: Expert Review,Literature\nMode of inheritance for gene: TSC1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: TSC1 were set to PMID: 26540169\nReview for gene: TSC1 was set to GREEN\nAdded comment: Sources: Expert Review, Literature","entity_name":"TSC1","entity_type":"gene"},{"created":"2021-02-18T17:21:36.709216+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: KRT10: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 29135017, PMID: 25495838; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KRT10","entity_type":"gene"},{"created":"2021-02-18T17:21:31.530946+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"KRT10","entity_type":"gene"},{"created":"2021-02-18T17:21:24.221179+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: KRT1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 28532675, PMID: 17255957; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KRT1","entity_type":"gene"},{"created":"2021-02-18T17:21:19.691349+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"KRT1","entity_type":"gene"},{"created":"2021-02-18T17:20:58.675706+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"edited their review of gene: KRAS: Changed publications: PMID: 22499344, PMID: 22683711, PMID: 26970110, PMID: 25808193","entity_name":"KRAS","entity_type":"gene"},{"created":"2021-02-18T17:19:46.199745+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: KRAS: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22499344, PMID: 22683711; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KRAS","entity_type":"gene"},{"created":"2021-02-18T17:19:37.818680+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"KRAS","entity_type":"gene"},{"created":"2021-02-18T17:19:30.557013+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: IDH2: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID 22057234; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"IDH2","entity_type":"gene"},{"created":"2021-02-18T17:19:25.535265+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"IDH2","entity_type":"gene"},{"created":"2021-02-18T17:19:18.022378+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: IDH1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22057234; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"IDH1","entity_type":"gene"},{"created":"2021-02-18T17:19:12.948332+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"IDH1","entity_type":"gene"},{"created":"2021-02-18T17:19:06.234077+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: HRAS: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22499344, PMID: 22683711, PMID: 24006476; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"HRAS","entity_type":"gene"},{"created":"2021-02-18T17:19:00.653277+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"HRAS","entity_type":"gene"},{"created":"2021-02-18T17:18:37.913915+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"edited their review of gene: GNAS: Changed publications: PMID: 12970318, PMID: 15126527, PMID: 10646121, PMID: 1594625, PMID: 1944469","entity_name":"GNAS","entity_type":"gene"},{"created":"2021-02-18T17:14:18.009198+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: GNAS: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 12970318; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"GNAS","entity_type":"gene"},{"created":"2021-02-18T17:14:10.766318+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"GNAS","entity_type":"gene"},{"created":"2021-02-18T17:13:51.456485+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: GNAQ: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 26778290; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"GNAQ","entity_type":"gene"},{"created":"2021-02-18T17:13:46.103468+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"GNAQ","entity_type":"gene"},{"created":"2021-02-18T17:13:39.292193+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: GNA14: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 27476652; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"GNA14","entity_type":"gene"},{"created":"2021-02-18T17:13:33.490442+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"GNA14","entity_type":"gene"},{"created":"2021-02-18T17:13:26.110321+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: GNA11: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 26778290; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"GNA11","entity_type":"gene"},{"created":"2021-02-18T17:13:20.026517+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"GNA11","entity_type":"gene"},{"created":"2021-02-18T17:13:12.294494+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: FGFR3: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 16841094, PMID: 22499344; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"FGFR3","entity_type":"gene"},{"created":"2021-02-18T17:13:04.203815+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"FGFR3","entity_type":"gene"},{"created":"2021-02-18T17:12:56.300377+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: FGFR1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 26942290; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"FGFR1","entity_type":"gene"},{"created":"2021-02-18T17:12:49.740739+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"FGFR1","entity_type":"gene"},{"created":"2021-02-18T17:12:35.892830+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: AKT1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 21793738; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"AKT1","entity_type":"gene"},{"created":"2021-02-18T17:12:29.904420+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"AKT1","entity_type":"gene"},{"created":"2021-02-18T17:12:14.245258+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: ACTB: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 28347698; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"ACTB","entity_type":"gene"},{"created":"2021-02-18T17:12:07.226905+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"ACTB","entity_type":"gene"},{"created":"2021-02-18T17:11:47.955561+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: SPRED1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 27423141; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SPRED1","entity_type":"gene"},{"created":"2021-02-18T17:11:21.289718+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: SMO: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 27236920; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SMO","entity_type":"gene"},{"created":"2021-02-18T17:11:00.424863+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: RHOA: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 31570889; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RHOA","entity_type":"gene"},{"created":"2021-02-18T17:10:26.108687+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: RASA1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 24038909, PMID: 30635911; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RASA1","entity_type":"gene"},{"created":"2021-02-18T17:09:46.958626+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: PTEN: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 10749983, PMID: 12471211; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PTEN","entity_type":"gene"},{"created":"2021-02-18T17:09:13.296225+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: PIK3CA: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22499344, PMID: 22729224, PMID: 29446767, PMID: 23100325; Phenotypes: ; Mode of inheritance: None","entity_name":"PIK3CA","entity_type":"gene"},{"created":"2021-02-18T17:08:45.451203+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: NRAS: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22499344, PMID: 24006476, PMID: 10878667; Phenotypes: ; Mode of inheritance: None","entity_name":"NRAS","entity_type":"gene"},{"created":"2021-02-18T17:07:51.186939+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: NF1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 17668375, PMID: 14605872; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NF1","entity_type":"gene"},{"created":"2021-02-18T17:06:26.934707+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: MTOR: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 27159400; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"MTOR","entity_type":"gene"},{"created":"2021-02-18T17:05:52.053563+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: MAP3K3: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 25728774; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"MAP3K3","entity_type":"gene"},{"created":"2021-02-18T17:05:21.484133+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: MAP2K1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 29461977; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"MAP2K1","entity_type":"gene"},{"created":"2021-02-18T17:04:29.821887+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: KRT10: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 29135017, PMID: 25495838; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KRT10","entity_type":"gene"},{"created":"2021-02-18T17:03:52.784320+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: KRT1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 28532675, PMID: 17255957; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KRT1","entity_type":"gene"},{"created":"2021-02-18T17:02:04.112576+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: KRAS: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22499344, PMID: 22683711; Phenotypes: Linear sebaceous nevus syndrome (163200), Oculoectodermal syndrome (600268); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KRAS","entity_type":"gene"},{"created":"2021-02-18T16:58:53.774990+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: IDH2: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID 22057234; Phenotypes: Maffucci syndrome, Ollier disease; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"IDH2","entity_type":"gene"},{"created":"2021-02-18T16:57:07.372094+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: ACTB: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 28347698; Phenotypes: Becker naevus (604919); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"ACTB","entity_type":"gene"},{"created":"2021-02-18T16:56:53.232547+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"ACTB","entity_type":"gene"},{"created":"2021-02-18T16:56:08.658217+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: IDH1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22057234; Phenotypes: Maffucci syndrome, Ollier disease; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"IDH1","entity_type":"gene"},{"created":"2021-02-18T16:55:45.851724+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"IDH1","entity_type":"gene"},{"created":"2021-02-18T16:55:25.851703+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: IDH1: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 22057234; Phenotypes: Maffucci syndrome, Ollier disease; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"IDH1","entity_type":"gene"},{"created":"2021-02-18T16:54:17.410263+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: HRAS: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 22499344, PMID: 22683711, PMID: 24006476; Phenotypes: Epidermal nevus (162900), Linear sebaceous nevus syndrome (163200), Congenital melanocytic nevus (137550); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"HRAS","entity_type":"gene"},{"created":"2021-02-18T16:50:58.231595+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: GNA14: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 27476652; Phenotypes: tufted angiomas (TA), laposiform hemangioendotheliomas (KHE), lobular capillary hemangiomas (LCH); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"GNA14","entity_type":"gene"},{"created":"2021-02-18T16:48:33.538120+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: ACTB: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 28347698; Phenotypes: Becker naevus (604919); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"ACTB","entity_type":"gene"},{"created":"2021-02-18T16:47:21.381025+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: GNAS: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 12970318; Phenotypes: McCune-Albright syndrome (174800); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"GNAS","entity_type":"gene"},{"created":"2021-02-18T16:46:23.728123+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: GNAQ: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 26778290; Phenotypes: Sturge Weber syndrome, Phakomatosis pigmentovascularis; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"GNAQ","entity_type":"gene"},{"created":"2021-02-18T16:45:53.720265+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: GNA11: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 26778290; Phenotypes: Phakomatosis pigmentovascularis; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"GNA11","entity_type":"gene"},{"created":"2021-02-18T16:44:18.333202+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their comment","entity_name":"FGFR1","entity_type":"gene"},{"created":"2021-02-18T16:43:56.979449+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: FGFR3: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 16841094, PMID: 22499344; Phenotypes: Epidermal naevi (162900); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"FGFR3","entity_type":"gene"},{"created":"2021-02-18T16:38:17.935029+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: FGFR1: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 26942290; Phenotypes: Encephalocraniocutaneous Lipomatosis (613001); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"FGFR1","entity_type":"gene"},{"created":"2021-02-18T16:32:33.399450+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: AKT1: Rating: GREEN; Mode of pathogenicity: Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments; Publications: PMID: 21793738; Phenotypes: Proteus syndrome (176920); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"AKT1","entity_type":"gene"},{"created":"2021-02-18T16:31:59.568408+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"Deleted their review","entity_name":"AKT1","entity_type":"gene"},{"created":"2021-02-18T16:28:26.371406+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.1","user_name":"Mathew Wallis","item_type":"entity","text":"reviewed gene: AKT1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID 21793738; Phenotypes: Proteus syndrome (176920); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"AKT1","entity_type":"gene"},{"created":"2021-02-18T14:58:13.724613+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"0.128","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SPG7 as ready","entity_name":"SPG7","entity_type":"gene"},{"created":"2021-02-18T14:58:13.719358+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"0.128","user_name":"Zornitza Stark","item_type":"entity","text":"Added comment: Comment when marking as ready: Note bi-allelic variants are associated with spastic paraplegia.","entity_name":"SPG7","entity_type":"gene"},{"created":"2021-02-18T14:58:13.680598+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"0.128","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: spg7 has been classified as Green List (High Evidence).","entity_name":"SPG7","entity_type":"gene"},{"created":"2021-02-18T14:57:56.529311+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"0.128","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SPG7 were changed from  to autosomal dominant optical atrophy","entity_name":"SPG7","entity_type":"gene"},{"created":"2021-02-18T14:57:28.452409+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"0.127","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SPG7 were set to ","entity_name":"SPG7","entity_type":"gene"},{"created":"2021-02-18T14:56:58.400060+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"0.126","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SPG7 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SPG7","entity_type":"gene"},{"created":"2021-02-18T14:49:23.045975+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: CARD14 was added\ngene: CARD14 was added to Mosaic skin disorders. Sources: NHS GMS,Genomics England PanelApp,Expert Review Red\nMode of inheritance for gene: CARD14 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: CARD14 were set to ILVEN (submitted 2 cases)","entity_name":"CARD14","entity_type":"gene"},{"created":"2021-02-18T14:49:22.960642+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: TEK was added\ngene: TEK was added to Mosaic skin disorders. Sources: Expert Review Amber,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: TEK was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown\nPublications for gene: TEK were set to 27519652\nPhenotypes for gene: TEK were set to Venous malformations, multiple cutaneous and mucosal, 600195","entity_name":"TEK","entity_type":"gene"},{"created":"2021-02-18T14:49:22.914520+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: PTPN11 was added\ngene: PTPN11 was added to Mosaic skin disorders. Sources: Expert Review Amber,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: PTPN11 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: PTPN11 were set to Mosaic case series shortly to be published by Kinsler group\nPhenotypes for gene: PTPN11 were set to Noonan syndrome; Noonan syndrome with lentigines (LEOPARD)","entity_name":"PTPN11","entity_type":"gene"},{"created":"2021-02-18T14:49:22.869243+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: PMVK was added\ngene: PMVK was added to Mosaic skin disorders. Sources: Expert Review Amber,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: PMVK was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: PMVK were set to 30942823\nPhenotypes for gene: PMVK were set to Linear porokeratosis","entity_name":"PMVK","entity_type":"gene"},{"created":"2021-02-18T14:49:22.816252+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: MVD was added\ngene: MVD was added to Mosaic skin disorders. Sources: Expert Review Amber,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: MVD was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: MVD were set to 30942823\nPhenotypes for gene: MVD were set to Linear porokeratosis","entity_name":"MVD","entity_type":"gene"},{"created":"2021-02-18T14:49:22.767134+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: IKBKG was added\ngene: IKBKG was added to Mosaic skin disorders. Sources: Expert Review Amber,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: IKBKG was set to X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)\nPhenotypes for gene: IKBKG were set to Ectodermal dysplasia and immunodeficiency 1, 300291; Ectodermal, dysplasia, anhidrotic, lymphedema and immunodeficiency, 300301; Incontinentia pigmenti, 308300","entity_name":"IKBKG","entity_type":"gene"},{"created":"2021-02-18T14:49:22.723693+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: FGFR2 was added\ngene: FGFR2 was added to Mosaic skin disorders. Sources: Expert Review Amber,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: FGFR2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: FGFR2 were set to 9728990\nPhenotypes for gene: FGFR2 were set to Epdermal naevi","entity_name":"FGFR2","entity_type":"gene"},{"created":"2021-02-18T14:49:22.679854+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: ATP2A2 was added\ngene: ATP2A2 was added to Mosaic skin disorders. Sources: Expert Review Amber,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: ATP2A2 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","entity_name":"ATP2A2","entity_type":"gene"},{"created":"2021-02-18T14:49:22.636643+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SPRED1 was added\ngene: SPRED1 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: SPRED1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: SPRED1 were set to 27423141\nPhenotypes for gene: SPRED1 were set to Legius syndrome","entity_name":"SPRED1","entity_type":"gene"},{"created":"2021-02-18T14:49:22.592887+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SMO was added\ngene: SMO was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: SMO was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: SMO were set to 27236920\nPhenotypes for gene: SMO were set to Curry-Jones syndrome","entity_name":"SMO","entity_type":"gene"},{"created":"2021-02-18T14:49:22.540036+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: RHOA was added\ngene: RHOA was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: RHOA was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: RHOA were set to 31570889\nPhenotypes for gene: RHOA were set to Blaschko-linear hypopigmentation syndrome","entity_name":"RHOA","entity_type":"gene"},{"created":"2021-02-18T14:49:22.495605+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: RASA1 was added\ngene: RASA1 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: RASA1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: RASA1 were set to 30635911; 24038909\nPhenotypes for gene: RASA1 were set to Capillary malformation-arteriovenous malformation syndrome","entity_name":"RASA1","entity_type":"gene"},{"created":"2021-02-18T14:49:22.451844+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: PTEN was added\ngene: PTEN was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: PTEN was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: PTEN were set to 12471211; 10749983\nPhenotypes for gene: PTEN were set to Epidermal naevi; Cowden syndrome; Bannayan-Riley-Ruvalcaba syndrome; Melanoma","entity_name":"PTEN","entity_type":"gene"},{"created":"2021-02-18T14:49:22.406561+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: PIK3CA was added\ngene: PIK3CA was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: PIK3CA was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: PIK3CA were set to 22499344; 23100325; 22729224; 29446767\nPhenotypes for gene: PIK3CA were set to Vascular malformations; PIK3CA-related overgrowth syndromes","entity_name":"PIK3CA","entity_type":"gene"},{"created":"2021-02-18T14:49:22.361004+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: NRAS was added\ngene: NRAS was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: NRAS was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: NRAS were set to 22499344; 24006476; 10878667\nPhenotypes for gene: NRAS were set to Noonan syndrome; Melanocytic naevi; Congenital melanocytic naevus syndrome","entity_name":"NRAS","entity_type":"gene"},{"created":"2021-02-18T14:49:22.316167+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: NF2 was added\ngene: NF2 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: NF2 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown\nPublications for gene: NF2 were set to 29409008\nPhenotypes for gene: NF2 were set to NF2; NEUROFIBROMATOSIS, TYPE II","entity_name":"NF2","entity_type":"gene"},{"created":"2021-02-18T14:49:22.273502+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: NF1 was added\ngene: NF1 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: NF1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: NF1 were set to 14605872; 17668375\nPhenotypes for gene: NF1 were set to Neurofibromatosis type I","entity_name":"NF1","entity_type":"gene"},{"created":"2021-02-18T14:49:22.226656+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: MTOR was added\ngene: MTOR was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: MTOR was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: MTOR were set to 27159400\nPhenotypes for gene: MTOR were set to Hypomelanosis of Ito/Blaschko-linear hypopigmentation","entity_name":"MTOR","entity_type":"gene"},{"created":"2021-02-18T14:49:22.180416+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: MAP3K3 was added\ngene: MAP3K3 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: MAP3K3 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: MAP3K3 were set to 25728774\nPhenotypes for gene: MAP3K3 were set to Verrucous haemangiomas","entity_name":"MAP3K3","entity_type":"gene"},{"created":"2021-02-18T14:49:22.131626+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: MAP2K1 was added\ngene: MAP2K1 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: MAP2K1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: MAP2K1 were set to 29461977\nPhenotypes for gene: MAP2K1 were set to Cardio-facio-cutaneous syndrome","entity_name":"MAP2K1","entity_type":"gene"},{"created":"2021-02-18T14:49:22.087398+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: KRT10 was added\ngene: KRT10 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: KRT10 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: KRT10 were set to 25495838; 29135017\nPhenotypes for gene: KRT10 were set to Epidermolytic hyperkeratosis; Pachyonychia congenita; Ichythosis with confetti; Palmoplantar keratoderma","entity_name":"KRT10","entity_type":"gene"},{"created":"2021-02-18T14:49:22.040256+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: KRT1 was added\ngene: KRT1 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: KRT1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: KRT1 were set to 28532675; 17255957\nPhenotypes for gene: KRT1 were set to Ichthyosis histrix; Epidermolytic hyperkeratosis; Palmoplantar keratoderma","entity_name":"KRT1","entity_type":"gene"},{"created":"2021-02-18T14:49:21.993696+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: KRAS was added\ngene: KRAS was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: KRAS was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: KRAS were set to 22499344; 22683711\nPhenotypes for gene: KRAS were set to Epidermal naevi; Schimmelpenning syndrome","entity_name":"KRAS","entity_type":"gene"},{"created":"2021-02-18T14:49:21.951716+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: IDH2 was added\ngene: IDH2 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: IDH2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: IDH2 were set to 22057234\nPhenotypes for gene: IDH2 were set to Maffucci syndrome; Ollier disease","entity_name":"IDH2","entity_type":"gene"},{"created":"2021-02-18T14:49:21.909708+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: IDH1 was added\ngene: IDH1 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: IDH1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: IDH1 were set to 22057234\nPhenotypes for gene: IDH1 were set to Maffucci syndrome; Ollier disease","entity_name":"IDH1","entity_type":"gene"},{"created":"2021-02-18T14:49:21.868136+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: HRAS was added\ngene: HRAS was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: HRAS was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: HRAS were set to 22499344; 22683711; 24006476\nPhenotypes for gene: HRAS were set to Phakomatosis pigmentokeratotica; Epidermal naevi; Woolly hair; Costello syndrome; Schimmelpenning syndrome","entity_name":"HRAS","entity_type":"gene"},{"created":"2021-02-18T14:49:21.826989+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: GNAS was added\ngene: GNAS was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: GNAS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown\nPublications for gene: GNAS were set to 12970318\nPhenotypes for gene: GNAS were set to McCune-Albright syndrome","entity_name":"GNAS","entity_type":"gene"},{"created":"2021-02-18T14:49:21.782545+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: GNAQ was added\ngene: GNAQ was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: GNAQ was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: GNAQ were set to 26778290\nPhenotypes for gene: GNAQ were set to Extensive dermal melanocytosis; Sturge Weber syndrome; Phakomatosis pigmentovascularis","entity_name":"GNAQ","entity_type":"gene"},{"created":"2021-02-18T14:49:21.740119+11:00","panel_name":"Mosaic skin disorders","panel_id":3472,"panel_version":"0.0","user_name":"Zornitza Stark","item_type":"entity","text":"gene: GNA14 was added\ngene: GNA14 was added to Mosaic skin disorders. Sources: Expert Review Green,NHS GMS,Genomics England PanelApp\nMode of inheritance for gene: GNA14 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: GNA14 were set to 27476652\nPhenotypes for gene: GNA14 were set to Kaposiform endothelioma; Tufted angioma","entity_name":"GNA14","entity_type":"gene"}]}