{"count":220257,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1411","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1409","results":[{"created":"2021-02-13T19:57:21.795698+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.84","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lama3 has been classified as Green List (High Evidence).","entity_name":"LAMA3","entity_type":"gene"},{"created":"2021-02-13T19:57:18.519482+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.84","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LAMA3 were changed from  to Epidermolysis bullosa, generalized atrophic benign, MIM# 226650; Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700","entity_name":"LAMA3","entity_type":"gene"},{"created":"2021-02-13T19:56:54.527647+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.83","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LAMA3 were set to ","entity_name":"LAMA3","entity_type":"gene"},{"created":"2021-02-13T19:56:24.579069+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.82","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LAMA3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMA3","entity_type":"gene"},{"created":"2021-02-13T19:55:54.636197+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.81","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LAMA3: Rating: GREEN; Mode of pathogenicity: None; Publications: 7633458, 8530087, 11810295, 10366601; Phenotypes: Epidermolysis bullosa, generalized atrophic benign, MIM# 226650, Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMA3","entity_type":"gene"},{"created":"2021-02-13T18:28:32.914440+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6350","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LAMB3 as ready","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:28:32.903305+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6350","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lamb3 has been classified as Green List (High Evidence).","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:28:25.751995+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6350","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LAMB3 were changed from  to Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700; Epidermolysis bullosa, junctional, non-Herlitz type, MIM# 226650","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:27:54.612733+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6349","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LAMB3 were set to ","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:27:35.436448+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6348","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LAMB3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:27:12.935142+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6347","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LAMB3: Rating: GREEN; Mode of pathogenicity: None; Publications: 11023379, 7706760; Phenotypes: Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700, Epidermolysis bullosa, junctional, non-Herlitz type, MIM# 226650; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:26:15.090910+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.81","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LAMB3 as ready","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:26:15.078868+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.81","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lamb3 has been classified as Green List (High Evidence).","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:26:05.330855+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.81","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LAMB3 were changed from  to Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700; Epidermolysis bullosa, junctional, non-Herlitz type, MIM# 226650","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:25:37.558388+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.80","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LAMB3 were set to ","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:25:10.050469+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.79","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LAMB3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:24:38.358136+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.78","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LAMB3: Rating: GREEN; Mode of pathogenicity: None; Publications: 11023379, 7706760; Phenotypes: Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700, Epidermolysis bullosa, junctional, non-Herlitz type, MIM# 226650; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMB3","entity_type":"gene"},{"created":"2021-02-13T18:22:32.353574+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6347","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LAMC2 as ready","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:22:32.346100+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6347","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lamc2 has been classified as Green List (High Evidence).","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:22:24.385639+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6347","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LAMC2 were changed from  to Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700; Epidermolysis bullosa, junctional, non-Herlitz type, MIM# 226650","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:22:05.961237+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6346","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LAMC2 were set to ","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:21:47.857313+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6345","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LAMC2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:21:29.395158+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6344","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LAMC2: Rating: GREEN; Mode of pathogenicity: None; Publications: 11810295, 25888738, 24533970; Phenotypes: Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700, Epidermolysis bullosa, junctional, non-Herlitz type, MIM# 226650; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:20:39.409369+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.78","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LAMC2 as ready","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:20:39.395791+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.78","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lamc2 has been classified as Green List (High Evidence).","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:20:34.512508+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.78","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LAMC2 were changed from  to Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700; Epidermolysis bullosa, junctional, non-Herlitz type, MIM# 226650","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:20:06.581936+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.77","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LAMC2 were set to ","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:19:36.038427+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.76","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LAMC2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:19:07.250754+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.75","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LAMC2: Rating: GREEN; Mode of pathogenicity: None; Publications: 11810295, 25888738, 24533970; Phenotypes: Epidermolysis bullosa, junctional, Herlitz type, MIM# 226700, Epidermolysis bullosa, junctional, non-Herlitz type, MIM# 226650; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LAMC2","entity_type":"gene"},{"created":"2021-02-13T18:16:08.251925+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6344","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KRT5 as ready","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:16:08.237886+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6344","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: krt5 has been classified as Green List (High Evidence).","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:15:47.702114+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6344","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KRT5 were changed from  to Dowling-Degos disease 1, MIM# 179850; Epidermolysis bullosa simplex-MCR, MIM# 609352; Epidermolysis bullosa simplex-MP 131960; Epidermolysis bullosa simplex, Dowling-Meara type, MIM# 131760; Epidermolysis bullosa simplex, Koebner type, MIM# 131900; Epidermolysis bullosa simplex, recessive 1, MIM# 601001; Epidermolysis bullosa simplex, Weber-Cockayne type, MIM# 131800","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:15:26.900091+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6343","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KRT5 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:15:08.108459+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6342","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KRT5: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Dowling-Degos disease 1, MIM# 179850, Epidermolysis bullosa simplex-MCR, MIM# 609352, Epidermolysis bullosa simplex-MP 131960, Epidermolysis bullosa simplex, Dowling-Meara type, MIM# 131760, Epidermolysis bullosa simplex, Koebner type, MIM# 131900, Epidermolysis bullosa simplex, recessive 1, MIM# 601001, Epidermolysis bullosa simplex, Weber-Cockayne type, MIM# 131800; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:14:19.201660+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.75","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KRT5 as ready","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:14:19.193677+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.75","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: krt5 has been classified as Green List (High Evidence).","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:14:15.918862+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.75","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KRT5 were changed from  to Dowling-Degos disease 1, MIM# 179850; Epidermolysis bullosa simplex-MCR, MIM# 609352; Epidermolysis bullosa simplex-MP 131960; Epidermolysis bullosa simplex, Dowling-Meara type, MIM# 131760; Epidermolysis bullosa simplex, Koebner type, MIM# 131900; Epidermolysis bullosa simplex, recessive 1, MIM# 601001; Epidermolysis bullosa simplex, Weber-Cockayne type, MIM# 131800","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:13:45.075160+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.74","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KRT5 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:13:14.341886+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.73","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KRT5: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Dowling-Degos disease 1, MIM# 179850, Epidermolysis bullosa simplex-MCR, MIM# 609352, Epidermolysis bullosa simplex-MP 131960, Epidermolysis bullosa simplex, Dowling-Meara type, MIM# 131760, Epidermolysis bullosa simplex, Koebner type, MIM# 131900, Epidermolysis bullosa simplex, recessive 1, MIM# 601001, Epidermolysis bullosa simplex, Weber-Cockayne type, MIM# 131800; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"KRT5","entity_type":"gene"},{"created":"2021-02-13T18:09:00.437456+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.73","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KLHL24 as ready","entity_name":"KLHL24","entity_type":"gene"},{"created":"2021-02-13T18:09:00.429391+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.73","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: klhl24 has been classified as Green List (High Evidence).","entity_name":"KLHL24","entity_type":"gene"},{"created":"2021-02-13T18:08:34.173754+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.73","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KLHL24 were changed from  to Epidermolysis bullosa simplex, generalized, with scarring and hair loss, MIM# 617294","entity_name":"KLHL24","entity_type":"gene"},{"created":"2021-02-13T18:08:03.700972+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.72","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KLHL24 were set to ","entity_name":"KLHL24","entity_type":"gene"},{"created":"2021-02-13T18:07:28.532434+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.71","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KLHL24 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KLHL24","entity_type":"gene"},{"created":"2021-02-13T18:06:59.442071+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KLHL24: Rating: GREEN; Mode of pathogenicity: None; Publications: 27889062, 27798626; Phenotypes: Epidermolysis bullosa simplex, generalized, with scarring and hair loss, MIM# 617294; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KLHL24","entity_type":"gene"},{"created":"2021-02-13T14:03:11.054977+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3440","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLCN6 were changed from Developmental delay; neurodegeneration to Neurodegeneration, childhood-onset, hypotonia, respiratory insufficiency and brain imaging abnormalities, MIM# 619173; Developmental delay; neurodegeneration","entity_name":"CLCN6","entity_type":"gene"},{"created":"2021-02-13T14:02:27.046788+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3439","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: CLCN6: Changed phenotypes: Neurodegeneration, childhood-onset, hypotonia, respiratory insufficiency and brain imaging abnormalities, MIM# 619173, Developmental delay, neurodegeneration","entity_name":"CLCN6","entity_type":"gene"},{"created":"2021-02-13T14:01:38.268286+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6342","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLCN6 were changed from Benign partial epilepsy; febrile seizures; NCL to Neurodegeneration, childhood-onset, hypotonia, respiratory insufficiency and brain imaging abnormalities, MIM# 619173; Neurodegeneration; Benign partial epilepsy; febrile seizures; NCL","entity_name":"CLCN6","entity_type":"gene"},{"created":"2021-02-13T14:01:21.874418+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6341","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CLCN6 were set to 25794116; 21107136","entity_name":"CLCN6","entity_type":"gene"},{"created":"2021-02-13T14:01:00.430117+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6340","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: CLCN6: Changed phenotypes: Neurodegeneration, childhood-onset, hypotonia, respiratory insufficiency and brain imaging abnormalities, MIM# 619173, Neurodegeneration, Benign partial epilepsy, febrile seizures, NCL","entity_name":"CLCN6","entity_type":"gene"},{"created":"2021-02-13T13:28:18.597823+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PKP1 as ready","entity_name":"PKP1","entity_type":"gene"},{"created":"2021-02-13T13:28:18.587256+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pkp1 has been classified as Green List (High Evidence).","entity_name":"PKP1","entity_type":"gene"},{"created":"2021-02-13T13:22:29.833841+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PKP1 were changed from  to Ectodermal dysplasia/skin fragility syndrome, MIM# 604536","entity_name":"PKP1","entity_type":"gene"},{"created":"2021-02-13T13:22:02.593164+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.69","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PKP1 were set to ","entity_name":"PKP1","entity_type":"gene"},{"created":"2021-02-13T13:21:35.000636+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.68","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PKP1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PKP1","entity_type":"gene"},{"created":"2021-02-13T13:21:05.536397+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.67","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PKP1: Rating: GREEN; Mode of pathogenicity: None; Publications: 24073657, 16781314, 11994137, 10951270, 32346906; Phenotypes: Ectodermal dysplasia/skin fragility syndrome, MIM# 604536; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PKP1","entity_type":"gene"},{"created":"2021-02-13T12:41:03.959723+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6340","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ITGA6 as ready","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T12:41:03.948362+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6340","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga6 has been classified as Green List (High Evidence).","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T12:36:11.414770+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6340","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ITGA6 were changed from  to Epidermolysis bullosa, junctional, with pyloric stenosis, MIM# 226730","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T12:33:06.727293+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6339","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ITGA6 were set to ","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T12:32:43.569620+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6338","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ITGA6 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T12:32:23.744895+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6337","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ITGA6: Rating: GREEN; Mode of pathogenicity: None; Publications: 31502654, 27607025, 9158140; Phenotypes: Epidermolysis bullosa, junctional, with pyloric stenosis, MIM# 226730; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T12:07:41.558919+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.67","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ITGA6 as ready","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T12:07:41.546757+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.67","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga6 has been classified as Green List (High Evidence).","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T12:07:37.023339+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.67","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ITGA6 were changed from  to Epidermolysis bullosa, junctional, with pyloric stenosis, MIM# 226730","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T11:57:12.159166+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.66","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ITGA6 were set to ","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T11:25:22.157188+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.65","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ITGA6 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T11:24:52.512468+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.64","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ITGA6: Rating: GREEN; Mode of pathogenicity: None; Publications: 31502654, 27607025, 9158140; Phenotypes: Epidermolysis bullosa, junctional, with pyloric stenosis, MIM# 226730; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA6","entity_type":"gene"},{"created":"2021-02-13T11:21:24.730269+11:00","panel_name":"Mackenzie's Mission_Reproductive Carrier Screening","panel_id":3139,"panel_version":"0.54","user_name":"Zornitza Stark","item_type":"entity","text":"gene: ITGA3 was added\ngene: ITGA3 was added to Mackenzie's Mission_Reproductive Carrier Screening. Sources: Expert Review\nMode of inheritance for gene: ITGA3 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: ITGA3 were set to 22512483; 25810266; 27717396; 32198874; 26854491\nPhenotypes for gene: ITGA3 were set to Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748\nReview for gene: ITGA3 was set to GREEN\nAdded comment: This is a neonatal multi-organ disorder that includes congenital interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa. The respiratory and renal features predominate, and lung involvement accounts for the commonly lethal course of the disease. More than 5 unrelated families reported. \nSources: Expert Review","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:19:45.705728+11:00","panel_name":"Mackenzie's Mission_Reproductive Carrier Screening","panel_id":3139,"panel_version":"0.53","user_name":"Zornitza Stark","item_type":"panel","text":"removed gene:ITGA3 from the panel","entity_name":null,"entity_type":null},{"created":"2021-02-13T11:18:02.315067+11:00","panel_name":"Mackenzie's Mission_Reproductive Carrier Screening","panel_id":3139,"panel_version":"0.52","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ITGA3 as Green List (high evidence)","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:18:02.294821+11:00","panel_name":"Mackenzie's Mission_Reproductive Carrier Screening","panel_id":3139,"panel_version":"0.52","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga3 has been classified as Green List (High Evidence).","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:17:50.962385+11:00","panel_name":"Mackenzie's Mission_Reproductive Carrier Screening","panel_id":3139,"panel_version":"0.51","user_name":"Zornitza Stark","item_type":"entity","text":"gene: ITGA3 was added\ngene: ITGA3 was added to Mackenzie's Mission_Reproductive Carrier Screening. Sources: Expert Review\nMode of inheritance for gene: ITGA3 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: ITGA3 were set to 22512483; 25810266; 27717396; 32198874; 26854491\nPhenotypes for gene: ITGA3 were set to Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748\nReview for gene: ITGA3 was set to GREEN\nAdded comment: This is a severe neonatal multi-organ disorder that includes congenital interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa. The respiratory and renal features predominate, and lung involvement accounts for the commonly lethal course of the disease. \r\n\r\nMore than 5 unrelated families reported. \nSources: Expert Review","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:16:02.201292+11:00","panel_name":"Additional findings_Paediatric","panel_id":3302,"panel_version":"0.196","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ITGA3 as ready","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:16:02.152227+11:00","panel_name":"Additional findings_Paediatric","panel_id":3302,"panel_version":"0.196","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga3 has been classified as Green List (High Evidence).","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:15:57.366810+11:00","panel_name":"Additional findings_Paediatric","panel_id":3302,"panel_version":"0.196","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ITGA3 as Green List (high evidence)","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:15:57.354475+11:00","panel_name":"Additional findings_Paediatric","panel_id":3302,"panel_version":"0.196","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga3 has been classified as Green List (High Evidence).","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:15:46.037559+11:00","panel_name":"Additional findings_Paediatric","panel_id":3302,"panel_version":"0.195","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ITGA3: Rating: GREEN; Mode of pathogenicity: None; Publications: 22512483, 25810266, 27717396, 32198874, 26854491; Phenotypes: Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:15:06.535549+11:00","panel_name":"Pulmonary Fibrosis_Interstitial Lung Disease","panel_id":162,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ITGA3 as ready","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:15:06.525127+11:00","panel_name":"Pulmonary Fibrosis_Interstitial Lung Disease","panel_id":162,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga3 has been classified as Green List (High Evidence).","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:15:04.271920+11:00","panel_name":"Pulmonary Fibrosis_Interstitial Lung Disease","panel_id":162,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ITGA3 were changed from  to Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:14:36.832509+11:00","panel_name":"Pulmonary Fibrosis_Interstitial Lung Disease","panel_id":162,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ITGA3 were set to ","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:14:14.700563+11:00","panel_name":"Pulmonary Fibrosis_Interstitial Lung Disease","panel_id":162,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ITGA3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:13:44.345284+11:00","panel_name":"Pulmonary Fibrosis_Interstitial Lung Disease","panel_id":162,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ITGA3: Rating: GREEN; Mode of pathogenicity: None; Publications: 22512483, 25810266, 27717396, 32198874, 26854491; Phenotypes: Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:13:05.710209+11:00","panel_name":"Proteinuria","panel_id":144,"panel_version":"0.155","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ITGA3 as ready","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:13:05.698929+11:00","panel_name":"Proteinuria","panel_id":144,"panel_version":"0.155","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga3 has been classified as Green List (High Evidence).","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:13:03.091440+11:00","panel_name":"Proteinuria","panel_id":144,"panel_version":"0.155","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ITGA3 were changed from  to Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:12:38.949084+11:00","panel_name":"Proteinuria","panel_id":144,"panel_version":"0.154","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ITGA3 were set to ","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:12:10.233935+11:00","panel_name":"Proteinuria","panel_id":144,"panel_version":"0.153","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ITGA3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:11:40.243328+11:00","panel_name":"Proteinuria","panel_id":144,"panel_version":"0.152","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ITGA3: Rating: GREEN; Mode of pathogenicity: None; Publications: 22512483, 25810266, 27717396, 32198874, 26854491; Phenotypes: Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:09:59.646999+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6337","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ITGA3 as ready","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:09:59.639201+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6337","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga3 has been classified as Green List (High Evidence).","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:09:51.705922+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6337","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ITGA3 were changed from  to Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:09:34.136243+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6336","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ITGA3 were set to ","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:09:14.211358+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6335","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ITGA3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:08:56.836310+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.6334","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ITGA3: Rating: GREEN; Mode of pathogenicity: None; Publications: 22512483, 25810266, 27717396, 32198874, 26854491; Phenotypes: Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:08:06.715286+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.64","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ITGA3 as ready","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:08:06.707791+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.64","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: itga3 has been classified as Green List (High Evidence).","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:08:01.449059+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.64","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ITGA3 were changed from  to Interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital, MIM# 614748","entity_name":"ITGA3","entity_type":"gene"},{"created":"2021-02-13T11:07:30.837926+11:00","panel_name":"Epidermolysis bullosa","panel_id":101,"panel_version":"0.63","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ITGA3 were set to ","entity_name":"ITGA3","entity_type":"gene"}]}