{"count":220324,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1457","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1455","results":[{"created":"2020-12-30T08:47:11.401888+11:00","panel_name":"Paroxysmal Dyskinesia","panel_id":259,"panel_version":"0.85","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KCNQ3: Rating: GREEN; Mode of pathogenicity: None; Publications: 33337327, 25524373, 24851285; Phenotypes: Seizures, benign neonatal, 2, MIM# 121201; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:46:34.824616+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3364","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KCNQ3 as ready","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:46:34.813998+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3364","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kcnq3 has been classified as Green List (High Evidence).","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:46:18.680812+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3364","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KCNQ3 were changed from  to Seizures, benign neonatal, 2, MIM# 121201","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:45:51.052188+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3363","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KCNQ3 were set to ","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:45:16.570587+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3362","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KCNQ3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:44:43.208896+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3361","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KCNQ3: Rating: GREEN; Mode of pathogenicity: None; Publications: 33337327, 25524373, 24851285; Phenotypes: Seizures, benign neonatal, 2, MIM# 121201; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:43:37.137637+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.990","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KCNQ3 as ready","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:43:37.125465+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.990","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kcnq3 has been classified as Green List (High Evidence).","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:43:34.273544+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.990","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KCNQ3 were changed from  to Seizures, benign neonatal, 2, MIM# 121201","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:43:04.290817+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.989","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KCNQ3 were set to ","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:42:35.242363+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.988","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KCNQ3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:41:55.700056+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.987","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KCNQ3: Rating: GREEN; Mode of pathogenicity: None; Publications: 33337327, 25524373, 24851285; Phenotypes: Seizures, benign neonatal, 2, MIM# 121201; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:40:37.904732+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5869","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KCNQ3 as ready","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:40:37.892987+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5869","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kcnq3 has been classified as Green List (High Evidence).","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:40:30.323443+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5869","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KCNQ3 were changed from  to Seizures, benign neonatal, 2, MIM# 121201","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:39:57.328312+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5868","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KCNQ3 were set to ","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:39:27.358574+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5867","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KCNQ3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:39:14.638311+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.58","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KCNQ3 were changed from  to Seizures, benign neonatal, 2, MIM# 121201","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:39:01.287838+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5866","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KCNQ3: Rating: GREEN; Mode of pathogenicity: None; Publications: 33337327; Phenotypes: Seizures, benign neonatal, 2, MIM# 121201; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:36:32.878479+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.57","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KCNQ3 were set to ","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:35:55.405056+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.56","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KCNQ3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:35:22.899737+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.55","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KCNQ3: Rating: GREEN; Mode of pathogenicity: None; Publications: 33337327; Phenotypes: Seizures, benign neonatal, 2, MIM# 121201; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ3","entity_type":"gene"},{"created":"2020-12-30T08:33:11.616247+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.55","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KCNQ2 as ready","entity_name":"KCNQ2","entity_type":"gene"},{"created":"2020-12-30T08:33:11.608026+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.55","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kcnq2 has been classified as Green List (High Evidence).","entity_name":"KCNQ2","entity_type":"gene"},{"created":"2020-12-30T08:33:08.611265+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.55","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KCNQ2 were changed from  to Myokymia, MIM# 121200; Seizures, benign neonatal, 1, MIM# 121200; Developmental and epileptic encephalopathy 7, MIM# 613720","entity_name":"KCNQ2","entity_type":"gene"},{"created":"2020-12-30T08:32:36.787010+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.54","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KCNQ2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ2","entity_type":"gene"},{"created":"2020-12-30T08:32:02.262781+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.53","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KCNQ2: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Myokymia, MIM# 121200, Seizures, benign neonatal, 1, MIM# 121200, Developmental and epileptic encephalopathy 7, MIM# 613720; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNQ2","entity_type":"gene"},{"created":"2020-12-30T08:28:26.951871+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3361","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACB were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability to Cardioacrofacial dysplasia 2, MIM# 619143; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:27:48.636450+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.3360","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PRKACB: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: Cardioacrofacial dysplasia 2, MIM# 619143; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:27:26.299826+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.184","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACB were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability to Cardioacrofacial dysplasia 2, MIM# 619143; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:26:50.409283+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.183","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PRKACB: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Cardioacrofacial dysplasia 2, MIM# 619143; Mode of inheritance: None","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:26:27.383634+11:00","panel_name":"Ciliopathies","panel_id":84,"panel_version":"0.221","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACB were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability to Cardioacrofacial dysplasia 2, MIM# 619143; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:25:44.271874+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5866","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PRKACB as ready","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:25:44.260389+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5866","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: prkacb has been classified as Green List (High Evidence).","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:25:36.034209+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5866","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACB were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability to Cardioacrofacial dysplasia 2, MIM# 619143; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:25:13.664660+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5865","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PRKACB: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Cardioacrofacial dysplasia 2, MIM# 619143; Mode of inheritance: None","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:24:53.041793+11:00","panel_name":"Ciliopathies","panel_id":84,"panel_version":"0.220","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: PRKACB: Changed phenotypes: Cardioacrofacial dysplasia 2, MIM# 619143, Postaxial hand polydactyly, Postaxial foot polydactyly, Common atrium, Atrioventricular canal defect, Narrow chest, Abnormality of the teeth, Intellectual disability","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:24:36.355581+11:00","panel_name":"Congenital Heart Defect","panel_id":76,"panel_version":"0.82","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACB were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability to Cardioacrofacial dysplasia 2, MIM# 619143; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:23:48.171631+11:00","panel_name":"Congenital Heart Defect","panel_id":76,"panel_version":"0.81","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PRKACB: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Cardioacrofacial dysplasia 2, MIM# 619143; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PRKACB","entity_type":"gene"},{"created":"2020-12-30T08:17:08.098703+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.183","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PRKACA as ready","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T08:17:08.088937+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.183","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: prkaca has been classified as Green List (High Evidence).","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T08:06:34.252424+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.183","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACA were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability to Cardioacrofacial dysplasia 1, MIM# 619142; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T08:05:58.053861+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.182","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PRKACA: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Cardioacrofacial dysplasia 1, MIM# 619142; Mode of inheritance: None","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T08:00:45.753711+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5865","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACA were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth to Cardioacrofacial dysplasia 1, MIM# 619142; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T08:00:21.621297+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5864","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PRKACA: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Cardioacrofacial dysplasia 1, MIM# 619142; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T07:59:43.864651+11:00","panel_name":"Ciliopathies","panel_id":84,"panel_version":"0.220","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACA were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability to Cardioacrofacial dysplasia 1, MIM# 619142; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T07:59:10.676415+11:00","panel_name":"Ciliopathies","panel_id":84,"panel_version":"0.219","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: PRKACA: Changed phenotypes: Cardioacrofacial dysplasia 1, MIM# 619142, Postaxial hand polydactyly, Postaxial foot polydactyly, Common atrium, Atrioventricular canal defect, Narrow chest, Abnormality of the teeth, Intellectual disability","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T07:58:52.674982+11:00","panel_name":"Congenital Heart Defect","panel_id":76,"panel_version":"0.81","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PRKACA were changed from Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability to Cardioacrofacial dysplasia 1, MIM# 619142; Postaxial hand polydactyly; Postaxial foot polydactyly; Common atrium; Atrioventricular canal defect; Narrow chest; Abnormality of the teeth; Intellectual disability","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-30T07:58:17.210712+11:00","panel_name":"Congenital Heart Defect","panel_id":76,"panel_version":"0.80","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PRKACA: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Cardioacrofacial dysplasia 1, MIM# 619142; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PRKACA","entity_type":"gene"},{"created":"2020-12-29T20:09:02.556176+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.53","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: CACNA1S as Red List (low evidence)","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:09:02.537283+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.53","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cacna1s has been classified as Red List (Low Evidence).","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:08:26.473256+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.52","user_name":"Zornitza Stark","item_type":"entity","text":"changed review comment from: Well established gene-disease association.; to: Well established gene-disease association but a skeletal muscle channelopathy.","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:08:12.010284+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.52","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: CACNA1S: Changed rating: RED","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:06:19.653847+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.52","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CACNA1S as ready","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:06:19.645320+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.52","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cacna1s has been classified as Green List (High Evidence).","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:06:15.345389+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.52","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CACNA1S were changed from  to Hypokalemic periodic paralysis, type 1, MIM# 170400","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:05:37.221463+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.51","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CACNA1S were set to ","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:05:03.853118+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.50","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CACNA1S was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T20:03:13.997095+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.49","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CACNA1S: Rating: GREEN; Mode of pathogenicity: None; Publications: 11591859; Phenotypes: Hypokalemic periodic paralysis, type 1, MIM# 170400; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"CACNA1S","entity_type":"gene"},{"created":"2020-12-29T19:22:48.316919+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.49","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC1A3 as ready","entity_name":"SLC1A3","entity_type":"gene"},{"created":"2020-12-29T19:22:48.309365+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.49","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc1a3 has been classified as Green List (High Evidence).","entity_name":"SLC1A3","entity_type":"gene"},{"created":"2020-12-29T19:22:35.017285+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.49","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SLC1A3 were changed from  to Episodic ataxia, type 6 MIM#612656","entity_name":"SLC1A3","entity_type":"gene"},{"created":"2020-12-29T19:22:03.547251+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.48","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SLC1A3 were set to ","entity_name":"SLC1A3","entity_type":"gene"},{"created":"2020-12-29T19:21:31.463182+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.47","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SLC1A3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SLC1A3","entity_type":"gene"},{"created":"2020-12-29T19:03:41.654089+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.46","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KCNA1 as ready","entity_name":"KCNA1","entity_type":"gene"},{"created":"2020-12-29T19:03:41.646472+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.46","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kcna1 has been classified as Green List (High Evidence).","entity_name":"KCNA1","entity_type":"gene"},{"created":"2020-12-29T19:03:36.092939+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.46","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KCNA1 were changed from Episodic ataxia/myokymia syndrome, MIM# 160120 to Episodic ataxia/myokymia syndrome, MIM# 160120","entity_name":"KCNA1","entity_type":"gene"},{"created":"2020-12-29T19:03:05.974266+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.45","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KCNA1 were changed from  to Episodic ataxia/myokymia syndrome, MIM# 160120","entity_name":"KCNA1","entity_type":"gene"},{"created":"2020-12-29T19:02:43.425613+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.44","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KCNA1 were set to 11026449","entity_name":"KCNA1","entity_type":"gene"},{"created":"2020-12-29T19:02:21.070917+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.44","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KCNA1 were set to ","entity_name":"KCNA1","entity_type":"gene"},{"created":"2020-12-29T19:01:55.417985+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.43","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of pathogenicity for gene: KCNA1 was changed from  to Other","entity_name":"KCNA1","entity_type":"gene"},{"created":"2020-12-29T19:01:30.190633+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.42","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KCNA1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KCNA1","entity_type":"gene"},{"created":"2020-12-29T19:00:37.057818+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.41","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CACNA1A as ready","entity_name":"CACNA1A","entity_type":"gene"},{"created":"2020-12-29T19:00:37.049736+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.41","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cacna1a has been classified as Green List (High Evidence).","entity_name":"CACNA1A","entity_type":"gene"},{"created":"2020-12-29T19:00:34.907783+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.41","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CACNA1A were changed from  to Episodic ataxia, type 2 MIM#108500","entity_name":"CACNA1A","entity_type":"gene"},{"created":"2020-12-29T19:00:07.311031+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.40","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CACNA1A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"CACNA1A","entity_type":"gene"},{"created":"2020-12-29T18:59:37.322279+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.39","user_name":"Zornitza Stark","item_type":"entity","text":"Tag STR tag was added to gene: CACNA1A.","entity_name":"CACNA1A","entity_type":"gene"},{"created":"2020-12-29T18:57:31.830738+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.38","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ATP1A3 as ready","entity_name":"ATP1A3","entity_type":"gene"},{"created":"2020-12-29T18:57:31.822636+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.38","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: atp1a3 has been classified as Green List (High Evidence).","entity_name":"ATP1A3","entity_type":"gene"},{"created":"2020-12-29T18:57:29.028402+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.38","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ATP1A3 were changed from  to Alternating hemiplegia of childhood 2, MIM# 614820; CAPOS syndrome, MIM# 601338; Dystonia-12, MIM# 128235","entity_name":"ATP1A3","entity_type":"gene"},{"created":"2020-12-29T18:57:06.895195+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.37","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ATP1A3 were set to 15260953; 22842232; 24468074","entity_name":"ATP1A3","entity_type":"gene"},{"created":"2020-12-29T18:56:44.957924+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.37","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ATP1A3 were set to ","entity_name":"ATP1A3","entity_type":"gene"},{"created":"2020-12-29T18:56:19.613497+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.36","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ATP1A3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"ATP1A3","entity_type":"gene"},{"created":"2020-12-29T18:55:46.634337+11:00","panel_name":"Brain Channelopathies","panel_id":74,"panel_version":"0.35","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ATP1A3: Rating: GREEN; Mode of pathogenicity: None; Publications: 15260953, 22842232, 24468074; Phenotypes: Alternating hemiplegia of childhood 2, MIM# 614820, CAPOS syndrome, MIM# 601338, Dystonia-12, MIM# 128235; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"ATP1A3","entity_type":"gene"},{"created":"2020-12-29T18:52:19.566337+11:00","panel_name":"Blepharophimosis","panel_id":55,"panel_version":"0.27","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TLK2 as ready","entity_name":"TLK2","entity_type":"gene"},{"created":"2020-12-29T18:52:19.555173+11:00","panel_name":"Blepharophimosis","panel_id":55,"panel_version":"0.27","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tlk2 has been classified as Green List (High Evidence).","entity_name":"TLK2","entity_type":"gene"},{"created":"2020-12-29T18:52:15.181795+11:00","panel_name":"Blepharophimosis","panel_id":55,"panel_version":"0.27","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TLK2 were changed from  to Mental retardation, autosomal dominant 57, MIM# 618050","entity_name":"TLK2","entity_type":"gene"},{"created":"2020-12-29T18:51:38.995534+11:00","panel_name":"Blepharophimosis","panel_id":55,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TLK2 were set to ","entity_name":"TLK2","entity_type":"gene"},{"created":"2020-12-29T18:51:13.324268+11:00","panel_name":"Blepharophimosis","panel_id":55,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TLK2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"TLK2","entity_type":"gene"},{"created":"2020-12-29T18:50:36.752344+11:00","panel_name":"Blepharophimosis","panel_id":55,"panel_version":"0.24","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TLK2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29861108; Phenotypes: Mental retardation, autosomal dominant 57, MIM# 618050; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"TLK2","entity_type":"gene"},{"created":"2020-12-29T18:48:37.360130+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5864","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SCARF2 as ready","entity_name":"SCARF2","entity_type":"gene"},{"created":"2020-12-29T18:48:37.352152+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5864","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: scarf2 has been classified as Green List (High Evidence).","entity_name":"SCARF2","entity_type":"gene"},{"created":"2020-12-29T18:48:28.478863+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5864","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SCARF2 were changed from  to Van den Ende-Gupta syndrome, MIM# 600920","entity_name":"SCARF2","entity_type":"gene"},{"created":"2020-12-29T18:47:38.722048+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5863","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SCARF2 were set to ","entity_name":"SCARF2","entity_type":"gene"},{"created":"2020-12-29T18:47:09.952368+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5862","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SCARF2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SCARF2","entity_type":"gene"},{"created":"2020-12-29T18:46:52.675182+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.5861","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SCARF2: Rating: GREEN; Mode of pathogenicity: None; Publications: 20887961, 23808541, 24478002, 27375131, 24478002; Phenotypes: Van den Ende-Gupta syndrome, MIM# 600920; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"SCARF2","entity_type":"gene"},{"created":"2020-12-29T18:46:11.953554+11:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.251","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SCARF2 as ready","entity_name":"SCARF2","entity_type":"gene"},{"created":"2020-12-29T18:46:11.945608+11:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.251","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: scarf2 has been classified as Green List (High Evidence).","entity_name":"SCARF2","entity_type":"gene"},{"created":"2020-12-29T18:46:09.051374+11:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.251","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SCARF2 were changed from  to Van den Ende-Gupta syndrome, MIM# 600920","entity_name":"SCARF2","entity_type":"gene"}]}