{"count":220759,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1589","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1587","results":[{"created":"2020-09-15T16:28:33.850230+10:00","panel_name":"Chromosome Breakage Disorders","panel_id":79,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: xrcc2 has been classified as Amber List (Moderate Evidence).","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:28:06.464424+10:00","panel_name":"Chromosome Breakage Disorders","panel_id":79,"panel_version":"0.27","user_name":"Zornitza Stark","item_type":"entity","text":"gene: XRCC2 was added\ngene: XRCC2 was added to Chromosome Breakage Disorders. Sources: Expert list\nMode of inheritance for gene: XRCC2 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: XRCC2 were set to 27208205; 22232082; 11118202\nPhenotypes for gene: XRCC2 were set to Fanconi anemia, complementation group U, MIM# 617247\nReview for gene: XRCC2 was set to AMBER\nAdded comment: Single family reported, functional data. \nSources: Expert list","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:26:37.836224+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4449","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: XRCC2 as ready","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:26:37.825910+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4449","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: xrcc2 has been classified as Amber List (Moderate Evidence).","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:26:28.337611+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4449","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: XRCC2 were changed from  to Fanconi anemia, complementation group U, MIM# 617247","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:25:54.939588+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4448","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: XRCC2 were set to ","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:25:32.833645+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4447","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: XRCC2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:25:13.660356+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4446","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: XRCC2 as Amber List (moderate evidence)","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:25:13.645348+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4446","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: xrcc2 has been classified as Amber List (Moderate Evidence).","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:24:56.665584+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4445","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: XRCC2: Rating: AMBER; Mode of pathogenicity: None; Publications: 27208205, 22232082, 11118202; Phenotypes: Fanconi anemia, complementation group U, MIM# 617247; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:24:09.939714+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.161","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: XRCC2 as ready","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:24:09.930602+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.161","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: xrcc2 has been classified as Amber List (Moderate Evidence).","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:24:04.067518+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.161","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: XRCC2 were changed from  to Fanconi anemia, complementation group U, MIM# 617247","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:23:36.392165+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.160","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: XRCC2 were set to ","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:23:09.199756+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.159","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: XRCC2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:22:45.550250+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.158","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: XRCC2 as Amber List (moderate evidence)","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:22:45.541582+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.158","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: xrcc2 has been classified as Amber List (Moderate Evidence).","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:22:22.493511+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.157","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: XRCC2: Rating: AMBER; Mode of pathogenicity: None; Publications: 27208205, 22232082, 11118202; Phenotypes: Fanconi anemia, complementation group U, MIM# 617247; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"XRCC2","entity_type":"gene"},{"created":"2020-09-15T16:14:18.769771+10:00","panel_name":"Bleeding Disorders","panel_id":54,"panel_version":"0.197","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: WIPF1 as ready","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:14:18.755575+10:00","panel_name":"Bleeding Disorders","panel_id":54,"panel_version":"0.197","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: wipf1 has been classified as Green List (High Evidence).","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:14:14.532368+10:00","panel_name":"Bleeding Disorders","panel_id":54,"panel_version":"0.197","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: WIPF1 as Green List (high evidence)","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:14:14.522354+10:00","panel_name":"Bleeding Disorders","panel_id":54,"panel_version":"0.197","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: wipf1 has been classified as Green List (High Evidence).","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:13:45.952657+10:00","panel_name":"Bleeding Disorders","panel_id":54,"panel_version":"0.196","user_name":"Zornitza Stark","item_type":"entity","text":"gene: WIPF1 was added\ngene: WIPF1 was added to Bleeding Disorders. Sources: Expert list\nMode of inheritance for gene: WIPF1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: WIPF1 were set to 27742395; 11869681; 22231303; 14757742; 9405671\nPhenotypes for gene: WIPF1 were set to Wiskott-Aldrich syndrome 2, MIM#\t614493\nReview for gene: WIPF1 was set to GREEN\nAdded comment: Two unrelated families reported, one with 4 affected individuals. Extensive functional data. \nSources: Expert list","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:12:24.712513+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.157","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: WIPF1 as ready","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:12:24.701654+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.157","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: wipf1 has been classified as Green List (High Evidence).","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:12:19.684149+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.157","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: WIPF1 as Green List (high evidence)","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:12:19.675133+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.157","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: wipf1 has been classified as Green List (High Evidence).","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T16:11:56.953151+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.156","user_name":"Zornitza Stark","item_type":"entity","text":"gene: WIPF1 was added\ngene: WIPF1 was added to Bone Marrow Failure. Sources: Expert list\nMode of inheritance for gene: WIPF1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: WIPF1 were set to 27742395; 11869681; 22231303; 14757742; 9405671\nPhenotypes for gene: WIPF1 were set to Wiskott-Aldrich syndrome 2, MIM#\t614493\nReview for gene: WIPF1 was set to GREEN\nAdded comment: Two unrelated families reported, one with 4 affected individuals. Extensive functional data. \nSources: Expert list","entity_name":"WIPF1","entity_type":"gene"},{"created":"2020-09-15T15:54:13.487901+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TSR2 as ready","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:54:13.471443+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:54:10.194842+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TSR2 were changed from  to Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:53:40.296147+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.15","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TSR2 were set to ","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:53:10.994506+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TSR2 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:52:44.764050+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.13","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSR2 as Red List (low evidence)","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:52:44.753657+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.13","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:52:17.269988+10:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TSR2: Rating: RED; Mode of pathogenicity: None; Publications: 24942156; Phenotypes: Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:51:29.583117+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4445","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TSR2 as ready","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:51:29.574072+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4445","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:51:16.094306+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4445","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TSR2 were changed from  to Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:50:52.946934+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4444","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TSR2 were set to ","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:50:34.186618+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4443","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TSR2 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:50:19.314533+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4442","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSR2 as Red List (low evidence)","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:50:19.300196+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4442","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:50:00.877371+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4441","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TSR2: Rating: RED; Mode of pathogenicity: None; Publications: 24942156; Phenotypes: Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:49:17.674152+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TSR2 as ready","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:49:17.662937+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:49:15.268369+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TSR2 were changed from  to Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:48:48.160862+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.13","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TSR2 were set to ","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:48:26.001505+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TSR2 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:48:00.912164+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSR2 as Red List (low evidence)","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:48:00.901642+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:47:34.421540+10:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TSR2: Rating: RED; Mode of pathogenicity: None; Publications: 24942156; Phenotypes: Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:46:46.424076+10:00","panel_name":"Diamond Blackfan anaemia","panel_id":98,"panel_version":"0.32","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TSR2 as ready","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:46:46.411569+10:00","panel_name":"Diamond Blackfan anaemia","panel_id":98,"panel_version":"0.32","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:46:43.552671+10:00","panel_name":"Diamond Blackfan anaemia","panel_id":98,"panel_version":"0.32","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TSR2 were changed from  to Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:46:20.469094+10:00","panel_name":"Diamond Blackfan anaemia","panel_id":98,"panel_version":"0.31","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TSR2 were set to ","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:45:51.661335+10:00","panel_name":"Diamond Blackfan anaemia","panel_id":98,"panel_version":"0.30","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TSR2 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:45:26.637036+10:00","panel_name":"Diamond Blackfan anaemia","panel_id":98,"panel_version":"0.29","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSR2 as Red List (low evidence)","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:45:26.626931+10:00","panel_name":"Diamond Blackfan anaemia","panel_id":98,"panel_version":"0.29","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:44:58.614388+10:00","panel_name":"Diamond Blackfan anaemia","panel_id":98,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TSR2: Rating: RED; Mode of pathogenicity: None; Publications: 24942156; Phenotypes: Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:38:55.990640+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.155","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TSR2 as ready","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:38:55.981516+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.155","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T15:38:51.884254+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.155","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TSR2 were changed from  to Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T14:15:23.889429+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.154","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TSR2 were set to ","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T14:15:09.224756+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.154","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TSR2 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T14:13:41.389709+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.153","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSR2 as Red List (low evidence)","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T14:13:41.379896+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.153","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsr2 has been classified as Red List (Low Evidence).","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T14:13:12.826437+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.152","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TSR2: Rating: RED; Mode of pathogenicity: None; Publications: 24942156; Phenotypes: Diamond-Blackfan anemia 14 with mandibulofacial dysostosis, MIM# 300946; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TSR2","entity_type":"gene"},{"created":"2020-09-15T14:06:18.045189+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4441","user_name":"Zornitza Stark","item_type":"entity","text":"Tag disputed tag was added to gene: SRP72.","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:06:05.543216+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4441","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SRP72 as ready","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:06:05.531732+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4441","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: srp72 has been classified as Amber List (Moderate Evidence).","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:05:57.779487+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4441","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SRP72 were changed from  to Bone marrow failure syndrome 1, MIM# 614675","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:05:39.002137+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4440","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SRP72 were set to ","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:05:21.568061+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4439","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SRP72 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:05:05.950894+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4438","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SRP72 as Amber List (moderate evidence)","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:05:05.939692+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4438","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: srp72 has been classified as Amber List (Moderate Evidence).","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:04:49.441389+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.4437","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SRP72: Rating: AMBER; Mode of pathogenicity: None; Publications: 22541560, 31254415; Phenotypes: Bone marrow failure syndrome 1, MIM# 614675; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:04:15.166100+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.152","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SRP72 as ready","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:04:15.154398+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.152","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: srp72 has been classified as Amber List (Moderate Evidence).","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:04:12.004671+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.152","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SRP72 were changed from  to Bone marrow failure syndrome 1, MIM# 614675","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:03:39.675725+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.151","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SRP72 were set to ","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:03:13.362931+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.150","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SRP72 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:02:37.030686+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.149","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SRP72 as Amber List (moderate evidence)","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:02:37.022002+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.149","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: srp72 has been classified as Amber List (Moderate Evidence).","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:02:14.781116+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.148","user_name":"Zornitza Stark","item_type":"entity","text":"Tag disputed tag was added to gene: SRP72.","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T14:02:05.775422+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.148","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SRP72: Rating: AMBER; Mode of pathogenicity: None; Publications: 22541560, 31254415; Phenotypes: Bone marrow failure syndrome 1, MIM# 614675; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SRP72","entity_type":"gene"},{"created":"2020-09-15T13:54:23.862370+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.148","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SMARCAL1 as ready","entity_name":"SMARCAL1","entity_type":"gene"},{"created":"2020-09-15T13:54:23.850758+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.148","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: smarcal1 has been classified as Green List (High Evidence).","entity_name":"SMARCAL1","entity_type":"gene"},{"created":"2020-09-15T13:54:20.923730+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.148","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SMARCAL1 were changed from  to Schimke immunoosseous dysplasia, MIM# 242900","entity_name":"SMARCAL1","entity_type":"gene"},{"created":"2020-09-15T13:53:52.766718+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.147","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SMARCAL1 were set to ","entity_name":"SMARCAL1","entity_type":"gene"},{"created":"2020-09-15T13:53:30.941787+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.146","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SMARCAL1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SMARCAL1","entity_type":"gene"},{"created":"2020-09-15T13:53:03.200940+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.145","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SMARCAL1: Rating: GREEN; Mode of pathogenicity: None; Publications: 11799392, 17089404; Phenotypes: Schimke immunoosseous dysplasia, MIM# 242900; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"SMARCAL1","entity_type":"gene"},{"created":"2020-09-15T13:49:31.475982+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.145","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLX4 as ready","entity_name":"SLX4","entity_type":"gene"},{"created":"2020-09-15T13:49:31.463180+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.145","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slx4 has been classified as Green List (High Evidence).","entity_name":"SLX4","entity_type":"gene"},{"created":"2020-09-15T13:49:28.775923+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.145","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SLX4 were changed from  to Fanconi anemia, complementation group P, MIM# 613951","entity_name":"SLX4","entity_type":"gene"},{"created":"2020-09-15T13:49:05.233928+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.144","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SLX4 were set to ","entity_name":"SLX4","entity_type":"gene"},{"created":"2020-09-15T13:47:44.809190+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.143","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SLX4 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLX4","entity_type":"gene"},{"created":"2020-09-15T13:47:12.942306+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.142","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SLX4: Rating: GREEN; Mode of pathogenicity: None; Publications: 21240275, 21240277; Phenotypes: Fanconi anemia, complementation group P, MIM# 613951; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLX4","entity_type":"gene"},{"created":"2020-09-15T13:45:29.475695+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.142","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC37A4 as ready","entity_name":"SLC37A4","entity_type":"gene"},{"created":"2020-09-15T13:45:29.464955+10:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.142","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc37a4 has been classified as Green List (High Evidence).","entity_name":"SLC37A4","entity_type":"gene"}]}