{"count":221272,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1631","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1629","results":[{"created":"2020-08-29T13:11:06.565961+10:00","panel_name":"Muscular dystrophy_Paediatric","panel_id":141,"panel_version":"0.71","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TMEM5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:10:42.695672+10:00","panel_name":"Muscular dystrophy_Paediatric","panel_id":141,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TMEM5: Rating: GREEN; Mode of pathogenicity: None; Publications: 23217329, 23519211; Phenotypes: Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 10, MIM# 615041; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:09:20.486233+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3985","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TMEM5 as ready","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:09:20.476198+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3985","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tmem5 has been classified as Green List (High Evidence).","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:09:13.834054+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3985","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TMEM5 were changed from  to Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 10, MIM# 615041","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:08:56.775443+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3984","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TMEM5 were set to ","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:08:38.727689+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3983","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TMEM5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:08:21.715568+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3982","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TMEM5: Rating: GREEN; Mode of pathogenicity: None; Publications: 23217329, 23519211; Phenotypes: Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 10, MIM# 615041; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:06:29.295708+10:00","panel_name":"Cobblestone Malformations","panel_id":6,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TMEM5 as ready","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:06:29.286321+10:00","panel_name":"Cobblestone Malformations","panel_id":6,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tmem5 has been classified as Green List (High Evidence).","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:06:26.992795+10:00","panel_name":"Cobblestone Malformations","panel_id":6,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TMEM5 were changed from  to Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 10, MIM# 615041","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:06:06.491781+10:00","panel_name":"Cobblestone Malformations","panel_id":6,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TMEM5 were set to ","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:05:28.372063+10:00","panel_name":"Cobblestone Malformations","panel_id":6,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TMEM5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:04:56.149941+10:00","panel_name":"Cobblestone Malformations","panel_id":6,"panel_version":"0.9","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TMEM5: Rating: GREEN; Mode of pathogenicity: None; Publications: 23217329, 23519211; Phenotypes: Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 10, MIM# 615041; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:04:13.588938+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.96","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TMEM5 as ready","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:04:13.577394+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.96","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tmem5 has been classified as Green List (High Evidence).","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:03:46.606086+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.96","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TMEM5 were changed from  to Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 10, MIM# 615041","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:03:25.947665+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.95","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TMEM5 were set to ","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:03:00.047232+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.94","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TMEM5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:02:30.255061+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.93","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: TMEM5: Changed publications: 23217329, 23519211","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T13:01:59.217620+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.93","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TMEM5: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 10, MIM# 615041; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMEM5","entity_type":"gene"},{"created":"2020-08-29T12:37:27.985803+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.201","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF5C as ready","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:37:27.976678+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.201","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif5c has been classified as Green List (High Evidence).","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:37:24.831622+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.201","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF5C were changed from  to Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:37:08.370858+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.200","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF5C were set to ","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:36:43.540000+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.199","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF5C was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:36:19.868918+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.198","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF5C: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 23033978, 32562872; Phenotypes: Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:35:41.147824+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2891","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF5C as ready","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:35:41.138948+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2891","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif5c has been classified as Green List (High Evidence).","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:35:37.156649+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2891","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF5C were changed from  to Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:34:31.008463+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2890","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF5C were set to ","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:34:28.297168+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.816","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF5C as ready","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:34:28.287152+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.816","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif5c has been classified as Green List (High Evidence).","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:34:07.590505+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2889","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF5C was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:33:37.641213+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.816","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF5C were changed from  to Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:33:37.637664+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2888","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF5C: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 23033978, 32562872; Phenotypes: Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:33:16.588449+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.815","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF5C were set to ","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:32:38.913818+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.814","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF5C was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:32:26.687578+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3982","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF5C as ready","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:32:26.678173+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3982","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif5c has been classified as Green List (High Evidence).","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:32:11.225128+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.813","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF5C: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 23033978, 32562872; Phenotypes: Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:31:23.307483+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3982","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF5C were changed from  to Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:30:42.322223+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3981","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF5C were set to ","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:30:25.317742+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3980","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF5C was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:30:07.268810+10:00","panel_name":"Polymicrogyria and Schizencephaly","panel_id":18,"panel_version":"0.142","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF5C as ready","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:30:07.258119+10:00","panel_name":"Polymicrogyria and Schizencephaly","panel_id":18,"panel_version":"0.142","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif5c has been classified as Green List (High Evidence).","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:30:04.848363+10:00","panel_name":"Polymicrogyria and Schizencephaly","panel_id":18,"panel_version":"0.142","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF5C were changed from  to Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:29:37.349750+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3979","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF5C: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 23033978, 32562872; Phenotypes: Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:29:31.242989+10:00","panel_name":"Polymicrogyria and Schizencephaly","panel_id":18,"panel_version":"0.141","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF5C were set to ","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:28:50.431877+10:00","panel_name":"Polymicrogyria and Schizencephaly","panel_id":18,"panel_version":"0.140","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF5C was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:28:25.105172+10:00","panel_name":"Polymicrogyria and Schizencephaly","panel_id":18,"panel_version":"0.139","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF5C: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 23033978, 32562872; Phenotypes: Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:05:53.942795+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.93","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF5C as ready","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:05:53.934664+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.93","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif5c has been classified as Green List (High Evidence).","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:05:51.776408+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.93","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF5C were changed from  to Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:05:31.391155+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.92","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF5C were set to ","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:03:53.145158+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.91","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF5C was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T12:03:25.091995+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.90","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF5C: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 23033978, 32562872; Phenotypes: Cortical dysplasia, complex, with other brain malformations 2, MIM# 615282; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF5C","entity_type":"gene"},{"created":"2020-08-29T11:52:38.022742+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.198","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF2A as ready","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:52:38.010961+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.198","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif2a has been classified as Red List (Low Evidence).","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:52:33.782604+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.198","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF2A were changed from  to Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:48:52.749372+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.197","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF2A were set to ","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:48:18.449150+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.196","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF2A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:47:57.594393+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.195","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: KIF2A as Red List (low evidence)","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:47:57.583992+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.195","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif2a has been classified as Red List (Low Evidence).","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:47:30.223990+10:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.194","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF2A: Rating: RED; Mode of pathogenicity: None; Publications: 23603762, 27896282, 27747449, 29077851, 31919497; Phenotypes: Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:45:38.803389+10:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.153","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF2A as ready","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:45:38.790429+10:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.153","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif2a has been classified as Green List (High Evidence).","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:45:35.124385+10:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.153","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: KIF2A as Green List (high evidence)","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:45:35.116433+10:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.153","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif2a has been classified as Green List (High Evidence).","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:45:12.105742+10:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.152","user_name":"Zornitza Stark","item_type":"entity","text":"gene: KIF2A was added\ngene: KIF2A was added to Microcephaly. Sources: Expert Review\nMode of inheritance for gene: KIF2A was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: KIF2A were set to 23603762; 27896282; 27747449; 29077851; 31919497\nPhenotypes for gene: KIF2A were set to Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411\nReview for gene: KIF2A was set to GREEN\nAdded comment: At least five unrelated families reported, with various malformations of cortical development including lissencephaly, agyria, posterior or frontal pachygyria, subcortical band heterotopia, and thin corpus callosum; microcephaly, intellectual disability and seizures. Microcephaly is in the range of -2SD -4.5SD, described as progressive in at least one individual. Some normocephalic but lower end of normal range. Some recurrent missense at p.Ser317 and p.His321. Functional data supports gene-disease association. \nSources: Expert Review","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:40:21.701380+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.813","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF2A as ready","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:40:21.693389+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.813","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif2a has been classified as Green List (High Evidence).","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:40:19.145688+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.813","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF2A were changed from  to Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:39:53.555269+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.812","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF2A were set to ","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:39:31.668516+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.811","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF2A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:38:45.352594+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.810","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF2A: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 27896282, 27747449, 29077851, 31919497; Phenotypes: Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:38:37.128947+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.90","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF2A as ready","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:38:37.119245+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.90","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif2a has been classified as Green List (High Evidence).","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:37:56.320463+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3979","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIF2A as ready","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:37:56.312158+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3979","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kif2a has been classified as Green List (High Evidence).","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:37:49.829346+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3979","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF2A were changed from  to Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:37:33.330224+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3978","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF2A were set to ","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:37:16.760630+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3977","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF2A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:37:00.523148+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3976","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF2A: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 27896282, 27747449, 29077851, 31919497; Phenotypes: Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:36:16.127322+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.90","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KIF2A were changed from  to Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:35:50.843127+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.89","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KIF2A were set to ","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:35:24.766733+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.88","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KIF2A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:35:00.436972+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.87","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KIF2A: Rating: GREEN; Mode of pathogenicity: None; Publications: 23603762, 27896282, 27747449, 29077851, 31919497; Phenotypes: Cortical dysplasia, complex, with other brain malformations 3, MIM# 615411; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KIF2A","entity_type":"gene"},{"created":"2020-08-29T11:28:57.647664+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.87","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: DCX as ready","entity_name":"DCX","entity_type":"gene"},{"created":"2020-08-29T11:28:57.639895+10:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.87","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: dcx has been classified as Green List (High Evidence).","entity_name":"DCX","entity_type":"gene"},{"created":"2020-08-29T11:28:20.326808+10:00","panel_name":"Limb Girdle Muscular Dystrophy","panel_id":3071,"panel_version":"0.53","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ISPD as ready","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:28:20.316254+10:00","panel_name":"Limb Girdle Muscular Dystrophy","panel_id":3071,"panel_version":"0.53","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ispd has been classified as Green List (High Evidence).","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:28:17.403557+10:00","panel_name":"Limb Girdle Muscular Dystrophy","panel_id":3071,"panel_version":"0.53","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ISPD were set to ","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:28:05.131767+10:00","panel_name":"Limb Girdle Muscular Dystrophy","panel_id":3071,"panel_version":"0.52","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ISPD: Rating: GREEN; Mode of pathogenicity: None; Publications: 23390185, 30060766, 28688748, 26404900; Phenotypes: Muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 7, MIM# 616052; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:26:08.441700+10:00","panel_name":"Muscular dystrophy_Paediatric","panel_id":141,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ISPD as ready","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:26:08.431303+10:00","panel_name":"Muscular dystrophy_Paediatric","panel_id":141,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ispd has been classified as Green List (High Evidence).","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:26:05.692393+10:00","panel_name":"Muscular dystrophy_Paediatric","panel_id":141,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ISPD were changed from  to Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 7, MIM# 614643; Muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 7, MIM# 616052","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:25:30.375089+10:00","panel_name":"Hydrocephalus_Ventriculomegaly","panel_id":115,"panel_version":"0.55","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ISPD were changed from Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 7, MIM# 614643; Muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 7, MIM# 616052 to Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 7, MIM# 614643","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:24:44.348330+10:00","panel_name":"Hydrocephalus_Ventriculomegaly","panel_id":115,"panel_version":"0.54","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ISPD were changed from  to Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 7, MIM# 614643; Muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 7, MIM# 616052","entity_name":"ISPD","entity_type":"gene"},{"created":"2020-08-29T11:23:37.300441+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3976","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ISPD as ready","entity_name":"ISPD","entity_type":"gene"}]}