{"count":221304,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1727","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1725","results":[{"created":"2020-07-16T18:10:19.673498+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2773","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: DEAF1 were set to ","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T18:09:56.577895+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2772","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: DEAF1 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T18:09:30.524687+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2771","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: DEAF1: Rating: GREEN; Mode of pathogenicity: None; Publications: 30923367, 24726472, 26048982, 28940898, 26834045; Phenotypes: Neurodevelopmental disorder with hypotonia, impaired expressive language, and with or without seizures 617171, Vulto-van Silfout-de Vries syndrome 615828; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T18:06:28.052610+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3372","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: DEAF1 as ready","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T18:06:28.044221+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3372","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: deaf1 has been classified as Green List (High Evidence).","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T18:06:21.388310+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3372","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: DEAF1 were changed from  to Neurodevelopmental disorder with hypotonia, impaired expressive language, and with or without seizures 617171; Vulto-van Silfout-de Vries syndrome 615828","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T18:06:00.295567+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3371","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: DEAF1 were set to ","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T18:05:39.059402+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3370","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of pathogenicity for gene: DEAF1 was changed from  to Other","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T18:05:24.481775+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3369","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: DEAF1 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T17:39:26.867258+10:00","panel_name":"Multiple pterygium syndrome","panel_id":139,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RIPK4 as ready","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:39:26.855976+10:00","panel_name":"Multiple pterygium syndrome","panel_id":139,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ripk4 has been classified as Green List (High Evidence).","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:39:05.921416+10:00","panel_name":"Multiple pterygium syndrome","panel_id":139,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RIPK4 as Green List (high evidence)","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:39:05.914198+10:00","panel_name":"Multiple pterygium syndrome","panel_id":139,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ripk4 has been classified as Green List (High Evidence).","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:38:43.215336+10:00","panel_name":"Multiple pterygium syndrome","panel_id":139,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"gene: RIPK4 was added\ngene: RIPK4 was added to Multiple pterygium syndrome. Sources: Expert Review\nMode of inheritance for gene: RIPK4 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: RIPK4 were set to 28940926; 22197489; 22197488\nPhenotypes for gene: RIPK4 were set to Popliteal pterygium syndrome, Bartsocas-Papas type, MIM# 263650\nReview for gene: RIPK4 was set to GREEN\nAdded comment: At least three unrelated families reported. \nSources: Expert Review","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:37:26.454305+10:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.189","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RIPK4 as ready","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:37:26.446736+10:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.189","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ripk4 has been classified as Green List (High Evidence).","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:37:24.222839+10:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.189","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RIPK4 were changed from  to Popliteal pterygium syndrome, Bartsocas-Papas type, MIM# 263650","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:37:00.830803+10:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.188","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RIPK4 were set to ","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:36:45.235681+10:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.187","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RIPK4 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T17:36:22.715604+10:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.186","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RIPK4: Rating: GREEN; Mode of pathogenicity: None; Publications: 28940926, 22197489, 22197488; Phenotypes: Popliteal pterygium syndrome, Bartsocas-Papas type, MIM# 263650; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RIPK4","entity_type":"gene"},{"created":"2020-07-16T16:49:49.819291+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3368","user_name":"Elena Savva","item_type":"entity","text":"reviewed gene: SMC3: Rating: GREEN; Mode of pathogenicity: Other; Publications: PMID: 18996922, 25655089, 31334757; Phenotypes: ornelia de Lange syndrome 3, 610759; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","entity_name":"SMC3","entity_type":"gene"},{"created":"2020-07-16T16:47:46.554460+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3368","user_name":"Elena Savva","item_type":"entity","text":"reviewed gene: DEAF1: Rating: GREEN; Mode of pathogenicity: Other; Publications: PMID 30923367, PMID 24726472; Phenotypes: Neurodevelopmental disorder with hypotonia, impaired expressive language, and with or without seizures 617171, Vulto-van Silfout-de Vries syndrome 615828; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"DEAF1","entity_type":"gene"},{"created":"2020-07-16T09:14:51.918345+10:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.753","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: GRM7 were changed from Epilepsy, microcephaly, developmental delay to Epilepsy, microcephaly, developmental delay; neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities (NEDSHBA), MIM#618922","entity_name":"GRM7","entity_type":"gene"},{"created":"2020-07-16T09:11:54.276134+10:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.140","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: GRM7 were changed from Epilepsy, microcephaly, developmental delay to Epilepsy, microcephaly, developmental delay; neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities (NEDSHBA), MIM#618922","entity_name":"GRM7","entity_type":"gene"},{"created":"2020-07-16T09:11:29.564608+10:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.139","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: GRM7: Changed phenotypes: Epilepsy, microcephaly, developmental delay, neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities (NEDSHBA), MIM#618922","entity_name":"GRM7","entity_type":"gene"},{"created":"2020-07-16T09:10:56.781950+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3368","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: GRM7 were changed from Epilepsy, microcephaly, developmental delay to Epilepsy, microcephaly, developmental delay; neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities (NEDSHBA), MIM#618922","entity_name":"GRM7","entity_type":"gene"},{"created":"2020-07-16T09:10:40.585007+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3367","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: GRM7: Changed phenotypes: Epilepsy, microcephaly, developmental delay, neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities (NEDSHBA), MIM#618922","entity_name":"GRM7","entity_type":"gene"},{"created":"2020-07-16T09:10:22.410597+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2771","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: GRM7 were changed from Epilepsy, microcephaly, developmental delay to Epilepsy, microcephaly, developmental delay; neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities (NEDSHBA), MIM#618922","entity_name":"GRM7","entity_type":"gene"},{"created":"2020-07-16T09:09:52.314348+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2770","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: GRM7: Changed phenotypes: Epilepsy, microcephaly, developmental delay, neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities (NEDSHBA), MIM#618922","entity_name":"GRM7","entity_type":"gene"},{"created":"2020-07-16T09:08:27.824269+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3367","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLCC1 were changed from Retinitis pigmentosa 32 to Retinitis pigmentosa 32, MIM# 609913","entity_name":"CLCC1","entity_type":"gene"},{"created":"2020-07-16T09:08:04.116836+10:00","panel_name":"Autosomal Recessive/X-Linked Retinitis Pigmentosa","panel_id":277,"panel_version":"0.56","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLCC1 were changed from Retinitis pigmentosa 32 to Retinitis pigmentosa 32, MIM# 609913","entity_name":"CLCC1","entity_type":"gene"},{"created":"2020-07-16T09:07:45.105480+10:00","panel_name":"Autosomal Recessive/X-Linked Retinitis Pigmentosa","panel_id":277,"panel_version":"0.55","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CLCC1: Rating: AMBER; Mode of pathogenicity: None; Publications: 30157172; Phenotypes: Retinitis pigmentosa 32, MIM# 609913; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"CLCC1","entity_type":"gene"},{"created":"2020-07-15T22:02:32.544917+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3366","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ABCC9 as ready","entity_name":"ABCC9","entity_type":"gene"},{"created":"2020-07-15T22:02:32.538536+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3366","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: abcc9 has been classified as Green List (High Evidence).","entity_name":"ABCC9","entity_type":"gene"},{"created":"2020-07-15T22:02:26.808988+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3366","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ABCC9 were changed from  to Hypertrichotic osteochondrodysplasia, MIM# 239850; Cantu syndrome; mild ID, similar facies, myopathy, cerebral white matter hyperintensities; cardiac systolic dysfunction","entity_name":"ABCC9","entity_type":"gene"},{"created":"2020-07-15T22:02:09.785605+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3365","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ABCC9 were set to ","entity_name":"ABCC9","entity_type":"gene"},{"created":"2020-07-15T22:01:53.950224+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3364","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ABCC9 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"ABCC9","entity_type":"gene"},{"created":"2020-07-15T22:01:37.634971+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3363","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ABCC9: Rating: GREEN; Mode of pathogenicity: Other; Publications: 31575858, 22610116, 22608503; Phenotypes: Hypertrichotic osteochondrodysplasia, MIM# 239850, Cantu syndrome, mild ID, similar facies, myopathy, cerebral white matter hyperintensities, cardiac systolic dysfunction; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"ABCC9","entity_type":"gene"},{"created":"2020-07-15T18:45:42.375550+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.93","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-07-15T18:44:50.432330+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.127","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-07-15T18:43:54.562042+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3363","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TSPYL1 as ready","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:43:54.554673+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3363","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tspyl1 has been classified as Amber List (Moderate Evidence).","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:43:48.605987+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3363","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TSPYL1 were changed from  to Sudden infant death with dysgenesis of the testes syndrome (MIM#608800)","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:43:32.964806+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3362","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TSPYL1 were set to ","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:43:17.230128+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3361","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TSPYL1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:43:01.912908+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3360","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSPYL1 as Amber List (moderate evidence)","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:43:01.904667+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3360","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tspyl1 has been classified as Amber List (Moderate Evidence).","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:42:47.833898+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.126","user_name":"Zornitza Stark","item_type":"entity","text":"Tag disputed tag was added to gene: TSPYL1.","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:42:37.736417+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3359","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TSPYL1: Rating: AMBER; Mode of pathogenicity: None; Publications: 15273283, 19463995, 22137496, 25449952, 16418600; Phenotypes: Sudden infant death with dysgenesis of the testes syndrome (MIM#608800); Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:41:29.490464+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.126","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSPYL1 as Amber List (moderate evidence)","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:41:29.483978+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.126","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tspyl1 has been classified as Amber List (Moderate Evidence).","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:40:46.107873+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.125","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TSPYL1 as ready","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:40:46.095999+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.125","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tspyl1 has been classified as Red List (Low Evidence).","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:40:43.183295+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.125","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TSPYL1 were changed from  to Sudden infant death with dysgenesis of the testes syndrome (MIM#608800)","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:40:18.232042+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.124","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TSPYL1 were set to ","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:39:57.691326+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.123","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TSPYL1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:39:36.921417+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.122","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSPYL1 as Red List (low evidence)","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:39:36.914132+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.122","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tspyl1 has been classified as Red List (Low Evidence).","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2020-07-15T18:38:20.359533+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.121","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: WDR11 as ready","entity_name":"WDR11","entity_type":"gene"},{"created":"2020-07-15T18:38:20.351968+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.121","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: wdr11 has been classified as Green List (High Evidence).","entity_name":"WDR11","entity_type":"gene"},{"created":"2020-07-15T18:38:17.625393+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.121","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: WDR11 were changed from  to Hypogonadotropic hypogonadism 14 with or without anosmia, MIM#614858","entity_name":"WDR11","entity_type":"gene"},{"created":"2020-07-15T18:37:55.736290+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.120","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: WDR11 were set to ","entity_name":"WDR11","entity_type":"gene"},{"created":"2020-07-15T18:37:30.700236+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.119","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: WDR11 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"WDR11","entity_type":"gene"},{"created":"2020-07-15T18:32:49.936135+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.118","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KISS1R as ready","entity_name":"KISS1R","entity_type":"gene"},{"created":"2020-07-15T18:32:49.925999+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.118","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kiss1r has been classified as Green List (High Evidence).","entity_name":"KISS1R","entity_type":"gene"},{"created":"2020-07-15T18:32:46.940522+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.118","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KISS1R were changed from  to Hypogonadotropic hypogonadism 8 with or without anosmia (MIM#614837)","entity_name":"KISS1R","entity_type":"gene"},{"created":"2020-07-15T18:32:25.436164+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.117","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KISS1R were set to ","entity_name":"KISS1R","entity_type":"gene"},{"created":"2020-07-15T18:32:03.600624+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.116","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KISS1R was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"KISS1R","entity_type":"gene"},{"created":"2020-07-15T18:12:51.666885+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.92","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PIGM were changed from portal vein thrombosis; persistent absence seizures; macrocephaly; infantile-onset cerebrovascular thrombotic events; portal vein thrombosis; persistent absence seizures; macrocephaly; infantile-onset cerebrovascular thrombotic events to portal vein thrombosis; persistent absence seizures; macrocephaly; infantile-onset cerebrovascular thrombotic events; portal vein thrombosis; persistent absence seizures; macrocephaly; infantile-onset cerebrovascular thrombotic events","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:12:38.061998+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.92","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PIGM were changed from portal vein thrombosis; persistent absence seizures; macrocephaly; infantile-onset cerebrovascular thrombotic events to portal vein thrombosis; persistent absence seizures; macrocephaly; infantile-onset cerebrovascular thrombotic events; portal vein thrombosis; persistent absence seizures; macrocephaly; infantile-onset cerebrovascular thrombotic events","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:12:24.966955+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3359","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PIGM as ready","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:12:24.956383+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3359","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pigm has been classified as Amber List (Moderate Evidence).","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:12:11.730672+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3359","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PIGM were changed from  to Glycosylphosphatidylinositol deficiency, MIM#\t610293; portal vein thrombosis; persistent absence seizures; macrocephaly; infantile-onset cerebrovascular thrombotic events","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:11:33.811414+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3358","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PIGM were set to ","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:11:18.771068+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3357","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PIGM was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:11:07.414949+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3356","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: PIGM as Amber List (moderate evidence)","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:11:07.404733+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3356","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pigm has been classified as Amber List (Moderate Evidence).","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:10:53.033793+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3355","user_name":"Zornitza Stark","item_type":"entity","text":"Tag founder tag was added to gene: PIGM.","entity_name":"PIGM","entity_type":"gene"},{"created":"2020-07-15T18:06:31.336194+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.115","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LEP as ready","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:06:31.323842+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.115","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lep has been classified as Green List (High Evidence).","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:06:18.160974+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3355","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LEP as ready","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:06:18.152663+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3355","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lep has been classified as Green List (High Evidence).","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:06:12.155608+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3355","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LEP were changed from  to Obesity, morbid, due to leptin deficiency (MIM#614962)","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:05:56.221185+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3354","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LEP were set to ","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:05:40.928738+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3353","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LEP was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:05:15.770031+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.115","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LEP were changed from Obesity, morbid, due to leptin deficiency (MIM#614962) to Obesity, morbid, due to leptin deficiency (MIM#614962)","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:05:06.718602+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.91","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ST3GAL3 as ready","entity_name":"ST3GAL3","entity_type":"gene"},{"created":"2020-07-15T18:05:06.711041+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.91","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: st3gal3 has been classified as Amber List (Moderate Evidence).","entity_name":"ST3GAL3","entity_type":"gene"},{"created":"2020-07-15T18:04:59.922263+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.115","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LEP were changed from  to Obesity, morbid, due to leptin deficiency (MIM#614962)","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:04:37.193336+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.114","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LEP were set to ","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:04:15.679714+10:00","panel_name":"Disorders of Sex Differentiation","panel_id":99,"panel_version":"0.113","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LEP was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LEP","entity_type":"gene"},{"created":"2020-07-15T18:01:10.213107+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.91","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NUS1 as ready","entity_name":"NUS1","entity_type":"gene"},{"created":"2020-07-15T18:01:10.202107+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.91","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nus1 has been classified as Amber List (Moderate Evidence).","entity_name":"NUS1","entity_type":"gene"},{"created":"2020-07-15T18:01:07.075037+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.91","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ST3GAL3 were changed from  to Mental retardation, autosomal recessive 12 MIM# 611090","entity_name":"ST3GAL3","entity_type":"gene"},{"created":"2020-07-15T18:00:53.501165+10:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.91","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NUS1 were set to ","entity_name":"NUS1","entity_type":"gene"},{"created":"2020-07-15T17:54:34.369657+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3352","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LEPR as ready","entity_name":"LEPR","entity_type":"gene"},{"created":"2020-07-15T17:54:34.363002+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3352","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lepr has been classified as Green List (High Evidence).","entity_name":"LEPR","entity_type":"gene"},{"created":"2020-07-15T17:54:27.952965+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3352","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LEPR were changed from  to Obesity, morbid, due to leptin receptor deficiency (MIM#614963)","entity_name":"LEPR","entity_type":"gene"},{"created":"2020-07-15T17:54:12.679631+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3351","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LEPR were set to ","entity_name":"LEPR","entity_type":"gene"},{"created":"2020-07-15T17:53:55.009716+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.3350","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LEPR was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LEPR","entity_type":"gene"}]}