{"count":221304,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1901","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1899","results":[{"created":"2020-03-18T14:44:56.611034+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.113","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: UQCRQ as ready","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:44:56.597024+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.113","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcrq has been classified as Red List (Low Evidence).","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:44:53.224652+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.113","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: UQCRQ were changed from  to Mitochondrial complex III deficiency, nuclear type 4, MIM# 615159","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:44:38.957839+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.193","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: UQCRQ as ready","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:44:38.948905+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.193","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcrq has been classified as Amber List (Moderate Evidence).","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:44:28.792726+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.112","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: UQCRQ were set to ","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:44:02.685664+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.193","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: UQCRQ were changed from  to Mitochondrial complex III deficiency, nuclear type 4, MIM# 615159","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:43:57.558737+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.111","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: UQCRQ was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:42:47.442915+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.110","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: UQCRQ as Red List (low evidence)","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:42:47.424135+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.110","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcrq has been classified as Red List (Low Evidence).","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:42:19.165499+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.109","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: UQCRQ: Rating: RED; Mode of pathogenicity: None; Publications: 18439546; Phenotypes: Mitochondrial complex III deficiency, nuclear type 4, MIM# 615159; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:41:49.906305+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.192","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: UQCRQ were set to ","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:41:22.820444+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.191","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: UQCRQ was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:40:32.773753+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.190","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: UQCRQ as Amber List (moderate evidence)","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:40:32.765495+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.190","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcrq has been classified as Amber List (Moderate Evidence).","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:39:55.668352+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.189","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: UQCRQ: Rating: AMBER; Mode of pathogenicity: None; Publications: 18439546; Phenotypes: Mitochondrial complex III deficiency, nuclear type 4, MIM# 615159; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCRQ","entity_type":"gene"},{"created":"2020-03-18T14:35:49.974869+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1761","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: UQCRC2 as ready","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:35:49.966167+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1761","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcrc2 has been classified as Amber List (Moderate Evidence).","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:35:32.179656+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1761","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: UQCRC2 were changed from  to Mitochondrial complex III deficiency, nuclear type 5, MIM# 615160","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:35:13.042156+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1760","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: UQCRC2 were set to ","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:34:52.853160+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1759","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: UQCRC2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:32:16.108710+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1758","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: UQCRC2 as Amber List (moderate evidence)","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:32:16.095587+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1758","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcrc2 has been classified as Amber List (Moderate Evidence).","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:31:55.474218+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.189","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: UQCRC2 as ready","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:31:55.465296+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.189","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcrc2 has been classified as Amber List (Moderate Evidence).","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:31:50.151806+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.189","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: UQCRC2 were changed from  to Mitochondrial complex III deficiency, nuclear type 5, MIM# 615160","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:31:24.196754+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1757","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: UQCRC2: Rating: AMBER; Mode of pathogenicity: None; Publications: 28275242, 23281071; Phenotypes: Mitochondrial complex III deficiency, nuclear type 5, MIM# 615160; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:31:17.052701+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.188","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: UQCRC2 were set to ","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:30:25.310788+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.187","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: UQCRC2 as Amber List (moderate evidence)","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:30:25.297492+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.187","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcrc2 has been classified as Amber List (Moderate Evidence).","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:30:08.591334+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1757","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: UQCC3 as ready","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:30:08.582724+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1757","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcc3 has been classified as Amber List (Moderate Evidence).","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:29:53.720105+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.186","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: UQCRC2: Rating: AMBER; Mode of pathogenicity: None; Publications: 28275242, 23281071; Phenotypes: Mitochondrial complex III deficiency, nuclear type 5, MIM# 615160; Mode of inheritance: None","entity_name":"UQCRC2","entity_type":"gene"},{"created":"2020-03-18T14:27:12.178958+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1757","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: UQCC3 were changed from  to Mitochondrial complex III deficiency, nuclear type 9, MIM# 616111","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:27:00.836452+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.186","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: UQCC3 as ready","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:27:00.827620+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.186","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcc3 has been classified as Amber List (Moderate Evidence).","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:26:38.554054+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.186","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: UQCC3 were changed from  to Mitochondrial complex III deficiency, nuclear type 9, MIM# 616111","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:26:09.014823+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1756","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: UQCC3 were set to ","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:25:53.445645+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1755","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: UQCC3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:25:35.055634+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1754","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: UQCC3 as Amber List (moderate evidence)","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:25:35.042287+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1754","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcc3 has been classified as Amber List (Moderate Evidence).","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:25:32.075664+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.185","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: UQCC3 were set to ","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:25:09.607282+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1753","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: UQCC3: Rating: AMBER; Mode of pathogenicity: None; Publications: 25008109, 28804536; Phenotypes: Mitochondrial complex III deficiency, nuclear type 9, MIM# 616111; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:24:46.291289+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.184","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: UQCC3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:24:15.716258+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.183","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: UQCC3 as Amber List (moderate evidence)","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:24:15.707692+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.183","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: uqcc3 has been classified as Amber List (Moderate Evidence).","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:23:39.836296+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.182","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: UQCC3: Rating: AMBER; Mode of pathogenicity: None; Publications: 25008109, 28804536; Phenotypes: Mitochondrial complex III deficiency, nuclear type 9, MIM# 616111; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"UQCC3","entity_type":"gene"},{"created":"2020-03-18T14:20:04.680777+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1753","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TXN2 as ready","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:20:04.671515+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1753","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: txn2 has been classified as Amber List (Moderate Evidence).","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:19:55.042828+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1753","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TXN2 were changed from  to Combined oxidative phosphorylation deficiency 29, MIM# 616811","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:19:43.475478+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.182","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TXN2 as ready","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:19:43.466352+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.182","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: txn2 has been classified as Amber List (Moderate Evidence).","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:19:37.670535+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.182","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TXN2 were changed from  to Combined oxidative phosphorylation deficiency 29, MIM# 616811","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:19:12.010750+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1752","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TXN2 were set to ","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:18:46.398498+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.181","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TXN2 were set to ","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:18:43.822618+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1751","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TXN2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:18:21.820956+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1750","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TXN2 as Amber List (moderate evidence)","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:18:21.809738+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1750","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: txn2 has been classified as Amber List (Moderate Evidence).","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:18:00.263071+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1749","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TXN2: Rating: AMBER; Mode of pathogenicity: None; Publications: 26626369, 12529397; Phenotypes: Combined oxidative phosphorylation deficiency 29, MIM# 616811; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:17:55.740345+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.180","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TXN2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:17:10.801518+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.179","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TXN2 as Amber List (moderate evidence)","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:17:10.786907+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.179","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: txn2 has been classified as Amber List (Moderate Evidence).","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:16:41.531595+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.178","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TXN2: Rating: AMBER; Mode of pathogenicity: None; Publications: 26626369, 12529397; Phenotypes: Combined oxidative phosphorylation deficiency 29, MIM# 616811; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TXN2","entity_type":"gene"},{"created":"2020-03-18T14:13:16.228491+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1749","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TARS2 as ready","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:13:16.215253+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1749","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tars2 has been classified as Amber List (Moderate Evidence).","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:13:03.183705+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1749","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TARS2 were changed from  to Combined oxidative phosphorylation deficiency 21, MIM# 615918","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:12:49.712933+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1748","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TARS2 were set to ","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:12:35.155265+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1747","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TARS2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:12:21.843463+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1746","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TARS2 as Amber List (moderate evidence)","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:12:21.829923+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1746","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tars2 has been classified as Amber List (Moderate Evidence).","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:12:01.438984+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1745","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TARS2: Rating: AMBER; Mode of pathogenicity: None; Publications: 24827421, 26811336; Phenotypes: Combined oxidative phosphorylation deficiency 21, MIM# 615918; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:11:10.533004+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.178","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TARS2 were changed from  to Combined oxidative phosphorylation deficiency 21, MIM# 615918","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:08:01.163345+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.177","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TARS2 were set to ","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:07:36.957892+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.176","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TARS2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:07:13.121912+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.175","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TARS2 as Amber List (moderate evidence)","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:07:13.108378+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.175","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tars2 has been classified as Amber List (Moderate Evidence).","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T14:06:40.238943+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.174","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TARS2: Rating: AMBER; Mode of pathogenicity: None; Publications: 24827421, 26811336; Phenotypes: Combined oxidative phosphorylation deficiency 21, MIM# 615918; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TARS2","entity_type":"gene"},{"created":"2020-03-18T13:00:28.105673+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.174","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: STAT2 as ready","entity_name":"STAT2","entity_type":"gene"},{"created":"2020-03-18T13:00:28.091457+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.174","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: stat2 has been classified as Green List (High Evidence).","entity_name":"STAT2","entity_type":"gene"},{"created":"2020-03-18T13:00:22.647852+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.174","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: STAT2 were changed from  to Immunodeficiency 44, MIM# 616636","entity_name":"STAT2","entity_type":"gene"},{"created":"2020-03-18T13:00:00.245611+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.173","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: STAT2 were set to ","entity_name":"STAT2","entity_type":"gene"},{"created":"2020-03-18T12:59:36.974546+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.172","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: STAT2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"STAT2","entity_type":"gene"},{"created":"2020-03-18T12:59:08.176018+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.171","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: STAT2: Rating: GREEN; Mode of pathogenicity: None; Publications: 23391734, 26122121; Phenotypes: Immunodeficiency 44, MIM# 616636; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"STAT2","entity_type":"gene"},{"created":"2020-03-18T12:55:59.913974+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.171","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC25A38 as ready","entity_name":"SLC25A38","entity_type":"gene"},{"created":"2020-03-18T12:55:59.905088+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.171","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc25a38 has been classified as Green List (High Evidence).","entity_name":"SLC25A38","entity_type":"gene"},{"created":"2020-03-18T12:55:46.436337+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.171","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SLC25A38 as Green List (high evidence)","entity_name":"SLC25A38","entity_type":"gene"},{"created":"2020-03-18T12:55:46.422732+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.171","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc25a38 has been classified as Green List (High Evidence).","entity_name":"SLC25A38","entity_type":"gene"},{"created":"2020-03-18T12:55:16.459424+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.170","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SLC25A38 was added\ngene: SLC25A38 was added to Mitochondrial disease. Sources: Expert list\nMode of inheritance for gene: SLC25A38 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: SLC25A38 were set to 19412178\nPhenotypes for gene: SLC25A38 were set to Anemia, sideroblastic, 2, pyridoxine-refractory, MIM#\t205950\nReview for gene: SLC25A38 was set to GREEN\nAdded comment: SLC25A38 belongs to the SLC25 family of mitochondrial carrier proteins. Multiple affected families reported together with an animal model. \nSources: Expert list","entity_name":"SLC25A38","entity_type":"gene"},{"created":"2020-03-18T12:51:33.508477+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1745","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC25A32 as ready","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:51:33.500158+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1745","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc25a32 has been classified as Green List (High Evidence).","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:51:25.216658+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1745","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SLC25A32 as Green List (high evidence)","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:51:25.203658+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1745","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc25a32 has been classified as Green List (High Evidence).","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:51:07.158885+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1744","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SLC25A32 was added\ngene: SLC25A32 was added to Mendeliome. Sources: Expert list\nMode of inheritance for gene: SLC25A32 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: SLC25A32 were set to 26933868; 28443623\nPhenotypes for gene: SLC25A32 were set to Exercise intolerance, riboflavin-responsive, MIM# 616839\nReview for gene: SLC25A32 was set to GREEN\nAdded comment: Two unrelated families reported with functional data. Muscle biopsy showed ragged-red fibers and lipid storage mainly in type I oxidative fibers, small type II fibers, and poor immunostaining for succinate dehydrogenase (FAD-dependent mitochondrial respiratory chain complex II). Oral supplementation with riboflavin led to dramatic improvement in the clinical and biologic abnormalities. \nSources: Expert list","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:50:48.781941+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.169","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC25A32 as ready","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:50:48.768634+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.169","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc25a32 has been classified as Green List (High Evidence).","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:50:12.460876+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.169","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SLC25A32 as Green List (high evidence)","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:50:12.451965+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.169","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc25a32 has been classified as Green List (High Evidence).","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:49:43.902162+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.168","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SLC25A32 was added\ngene: SLC25A32 was added to Mitochondrial disease. Sources: Expert list\nMode of inheritance for gene: SLC25A32 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: SLC25A32 were set to 26933868; 28443623\nPhenotypes for gene: SLC25A32 were set to Exercise intolerance, riboflavin-responsive, MIM# 616839\nReview for gene: SLC25A32 was set to GREEN\nAdded comment: Two unrelated families reported with functional data. Muscle biopsy showed ragged-red fibers and lipid storage mainly in type I oxidative fibers, small type II fibers, and poor immunostaining for succinate dehydrogenase (FAD-dependent mitochondrial respiratory chain complex II). Oral supplementation with riboflavin led to dramatic improvement in the clinical and biologic abnormalities. \nSources: Expert list","entity_name":"SLC25A32","entity_type":"gene"},{"created":"2020-03-18T12:31:43.404603+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.167","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SDHB as ready","entity_name":"SDHB","entity_type":"gene"},{"created":"2020-03-18T12:31:43.395070+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.167","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: sdhb has been classified as Amber List (Moderate Evidence).","entity_name":"SDHB","entity_type":"gene"}]}