{"count":221304,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1911","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1909","results":[{"created":"2020-03-04T15:49:00.298938+11:00","panel_name":"Congenital Myasthenia","panel_id":3078,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: MYO9A as ready","entity_name":"MYO9A","entity_type":"gene"},{"created":"2020-03-04T15:49:00.285128+11:00","panel_name":"Congenital Myasthenia","panel_id":3078,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: myo9a has been classified as Green List (High Evidence).","entity_name":"MYO9A","entity_type":"gene"},{"created":"2020-03-04T15:48:56.334521+11:00","panel_name":"Congenital Myasthenia","panel_id":3078,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: MYO9A were changed from congenital myasthenic syndrome 24, presynaptic 618198 to Congenital myasthenic syndrome 24, presynaptic 618198","entity_name":"MYO9A","entity_type":"gene"},{"created":"2020-03-04T15:48:42.940667+11:00","panel_name":"Congenital Myasthenia","panel_id":3078,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: MYO9A were set to ","entity_name":"MYO9A","entity_type":"gene"},{"created":"2020-03-04T15:47:04.863973+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.627","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SYNGAP1 as ready","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:47:04.855201+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.627","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: syngap1 has been classified as Green List (High Evidence).","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:47:01.439558+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.627","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SYNGAP1 were changed from  to Intellectual disability, autosomal dominant 5, MIM # 612621","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:46:29.638109+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.626","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SYNGAP1 were set to ","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:46:05.338919+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.625","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SYNGAP1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:45:35.514343+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.624","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SYNGAP1: Rating: GREEN; Mode of pathogenicity: None; Publications: 26079862; Phenotypes: Intellectual disability, autosomal dominant 5, MIM # 612621; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:43:29.688721+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2377","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SYNGAP1 as ready","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:43:29.679792+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2377","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: syngap1 has been classified as Green List (High Evidence).","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:43:21.214401+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2377","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SYNGAP1 were changed from  to Intellectual disability, autosomal dominant 5 (MIM # 612621)","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:42:49.209434+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2376","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SYNGAP1 were set to ","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:42:20.598225+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2375","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SYNGAP1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T15:37:35.994644+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2374","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NBN as ready","entity_name":"NBN","entity_type":"gene"},{"created":"2020-03-04T15:37:35.985350+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2374","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nbn has been classified as Amber List (Moderate Evidence).","entity_name":"NBN","entity_type":"gene"},{"created":"2020-03-04T15:37:29.324979+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2374","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NBN were changed from  to Nijmegen breakage syndrome, MIM# 251260","entity_name":"NBN","entity_type":"gene"},{"created":"2020-03-04T15:37:01.383551+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2373","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NBN was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NBN","entity_type":"gene"},{"created":"2020-03-04T15:36:26.340557+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2372","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NBN as Amber List (moderate evidence)","entity_name":"NBN","entity_type":"gene"},{"created":"2020-03-04T15:36:26.328065+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2372","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nbn has been classified as Amber List (Moderate Evidence).","entity_name":"NBN","entity_type":"gene"},{"created":"2020-03-04T15:35:43.346063+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2371","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NBN: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: Nijmegen breakage syndrome, MIM# 251260; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"NBN","entity_type":"gene"},{"created":"2020-03-04T15:24:46.916646+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2371","user_name":"Ain Roesley","item_type":"entity","text":"reviewed gene: SYNGAP1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 26079862; Phenotypes: Intellectual disability, autosomal dominant 5 (MIM # 612621); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SYNGAP1","entity_type":"gene"},{"created":"2020-03-04T13:54:29.424623+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Royal Melbourne Hospital; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-03-04T13:53:29.717208+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: BEST1 as ready","entity_name":"BEST1","entity_type":"gene"},{"created":"2020-03-04T13:53:29.708762+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: best1 has been classified as Green List (High Evidence).","entity_name":"BEST1","entity_type":"gene"},{"created":"2020-03-04T13:52:47.461763+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Royal Melbourne Hospital; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-03-04T13:51:56.818026+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LOXL3 as ready","entity_name":"LOXL3","entity_type":"gene"},{"created":"2020-03-04T13:51:56.805082+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: loxl3 has been classified as Amber List (Moderate Evidence).","entity_name":"LOXL3","entity_type":"gene"},{"created":"2020-03-04T13:51:37.039726+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COL9A3 as ready","entity_name":"COL9A3","entity_type":"gene"},{"created":"2020-03-04T13:51:37.031107+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: col9a3 has been classified as Green List (High Evidence).","entity_name":"COL9A3","entity_type":"gene"},{"created":"2020-03-04T13:45:41.895532+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: LOXL3 was added\ngene: LOXL3 was added to Stickler Syndrome. Sources: Expert list,Expert Review Amber\nMode of inheritance for gene: LOXL3 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: LOXL3 were set to 30362103; 25663169\nPhenotypes for gene: LOXL3 were set to Stickler syndrome","entity_name":"LOXL3","entity_type":"gene"},{"created":"2020-03-04T13:45:41.829956+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: ZNF408 was added\ngene: ZNF408 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: ZNF408 was set to Unknown","entity_name":"ZNF408","entity_type":"gene"},{"created":"2020-03-04T13:45:41.763030+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: VCAN was added\ngene: VCAN was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: VCAN was set to Unknown","entity_name":"VCAN","entity_type":"gene"},{"created":"2020-03-04T13:45:41.695567+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: TSPAN12 was added\ngene: TSPAN12 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: TSPAN12 was set to Unknown","entity_name":"TSPAN12","entity_type":"gene"},{"created":"2020-03-04T13:45:41.626986+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: NR2E3 was added\ngene: NR2E3 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: NR2E3 was set to Unknown","entity_name":"NR2E3","entity_type":"gene"},{"created":"2020-03-04T13:45:41.557182+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: NDP was added\ngene: NDP was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: NDP was set to Unknown","entity_name":"NDP","entity_type":"gene"},{"created":"2020-03-04T13:45:41.490550+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: LRP5 was added\ngene: LRP5 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: LRP5 was set to Unknown","entity_name":"LRP5","entity_type":"gene"},{"created":"2020-03-04T13:45:41.424268+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: KIF11 was added\ngene: KIF11 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: KIF11 was set to Unknown","entity_name":"KIF11","entity_type":"gene"},{"created":"2020-03-04T13:45:41.357207+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: KCNJ13 was added\ngene: KCNJ13 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: KCNJ13 was set to Unknown","entity_name":"KCNJ13","entity_type":"gene"},{"created":"2020-03-04T13:45:41.291283+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: GZF1 was added\ngene: GZF1 was added to Stickler Syndrome. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: GZF1 was set to Unknown","entity_name":"GZF1","entity_type":"gene"},{"created":"2020-03-04T13:45:41.223672+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: FZD4 was added\ngene: FZD4 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: FZD4 was set to Unknown","entity_name":"FZD4","entity_type":"gene"},{"created":"2020-03-04T13:45:41.154257+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: CTNNB1 was added\ngene: CTNNB1 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: CTNNB1 was set to Unknown","entity_name":"CTNNB1","entity_type":"gene"},{"created":"2020-03-04T13:45:41.087676+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: COL9A3 was added\ngene: COL9A3 was added to Stickler Syndrome. Sources: Expert Review Green,Other\nMode of inheritance for gene: COL9A3 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: COL9A3 were set to 31090205; 30450842; 20301479; 24273071\nPhenotypes for gene: COL9A3 were set to sensorineural hearing loss; midface hypoplasia; Stickler syndrome; myopia","entity_name":"COL9A3","entity_type":"gene"},{"created":"2020-03-04T13:45:41.021138+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: COL9A2 was added\ngene: COL9A2 was added to Stickler Syndrome. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: COL9A2 was set to Unknown","entity_name":"COL9A2","entity_type":"gene"},{"created":"2020-03-04T13:45:40.954719+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: COL9A1 was added\ngene: COL9A1 was added to Stickler Syndrome. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: COL9A1 was set to Unknown","entity_name":"COL9A1","entity_type":"gene"},{"created":"2020-03-04T13:45:40.888037+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: COL2A1 was added\ngene: COL2A1 was added to Stickler Syndrome. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: COL2A1 was set to Unknown","entity_name":"COL2A1","entity_type":"gene"},{"created":"2020-03-04T13:45:40.822879+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: COL18A1 was added\ngene: COL18A1 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: COL18A1 was set to Unknown","entity_name":"COL18A1","entity_type":"gene"},{"created":"2020-03-04T13:45:40.757255+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: COL11A2 was added\ngene: COL11A2 was added to Stickler Syndrome. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: COL11A2 was set to Unknown","entity_name":"COL11A2","entity_type":"gene"},{"created":"2020-03-04T13:45:40.675820+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: COL11A1 was added\ngene: COL11A1 was added to Stickler Syndrome. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: COL11A1 was set to Unknown","entity_name":"COL11A1","entity_type":"gene"},{"created":"2020-03-04T13:45:40.605343+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: CAPN5 was added\ngene: CAPN5 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: CAPN5 was set to Unknown","entity_name":"CAPN5","entity_type":"gene"},{"created":"2020-03-04T13:45:40.539136+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: BEST1 was added\ngene: BEST1 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: BEST1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: BEST1 were set to Vitreoretinochoroidopathy, MIM# 193220","entity_name":"BEST1","entity_type":"gene"},{"created":"2020-03-04T13:45:40.473189+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"entity","text":"gene: ATOH7 was added\ngene: ATOH7 was added to Vitreoretinopathy. Sources: Expert Review Green,Victorian Clinical Genetics Services\nMode of inheritance for gene: ATOH7 was set to Unknown","entity_name":"ATOH7","entity_type":"gene"},{"created":"2020-03-04T13:45:21.022482+11:00","panel_name":"Stickler Syndrome","panel_id":3114,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"panel","text":"Added panel Stickler Syndrome","entity_name":null,"entity_type":null},{"created":"2020-03-04T13:45:21.010035+11:00","panel_name":"Vitreoretinopathy","panel_id":3113,"panel_version":"0.0","user_name":"Alison Yeung","item_type":"panel","text":"Added panel Vitreoretinopathy","entity_name":null,"entity_type":null},{"created":"2020-03-04T12:31:47.602473+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1624","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ZDHHC15 as ready","entity_name":"ZDHHC15","entity_type":"gene"},{"created":"2020-03-04T12:31:47.586681+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1624","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zdhhc15 has been classified as Red List (Low Evidence).","entity_name":"ZDHHC15","entity_type":"gene"},{"created":"2020-03-04T12:31:32.847076+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1624","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ZDHHC15 were changed from  to Mental retardation, X-linked 91, 300577","entity_name":"ZDHHC15","entity_type":"gene"},{"created":"2020-03-04T12:31:18.584260+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1623","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ZDHHC15 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"ZDHHC15","entity_type":"gene"},{"created":"2020-03-04T12:31:06.045385+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1622","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ZDHHC15 as Red List (low evidence)","entity_name":"ZDHHC15","entity_type":"gene"},{"created":"2020-03-04T12:31:06.031741+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1622","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zdhhc15 has been classified as Red List (Low Evidence).","entity_name":"ZDHHC15","entity_type":"gene"},{"created":"2020-03-04T12:30:44.247668+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1621","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ZDHHC15: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Mental retardation, X-linked 91, 300577; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"ZDHHC15","entity_type":"gene"},{"created":"2020-03-04T11:33:07.106353+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2371","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ZBTB24 as ready","entity_name":"ZBTB24","entity_type":"gene"},{"created":"2020-03-04T11:33:07.092553+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2371","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zbtb24 has been classified as Green List (High Evidence).","entity_name":"ZBTB24","entity_type":"gene"},{"created":"2020-03-04T11:33:00.016208+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2371","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ZBTB24 were changed from  to Immunodeficiency-centromeric instability-facial anomalies syndrome 2; OMIM # 614069","entity_name":"ZBTB24","entity_type":"gene"},{"created":"2020-03-04T11:32:32.577571+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2370","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ZBTB24 were set to ","entity_name":"ZBTB24","entity_type":"gene"},{"created":"2020-03-04T11:32:02.923564+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2369","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ZBTB24 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ZBTB24","entity_type":"gene"},{"created":"2020-03-04T11:24:27.875465+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1621","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ZBTB16 as ready","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:24:27.867120+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1621","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zbtb16 has been classified as Amber List (Moderate Evidence).","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:23:59.510669+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1621","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ZBTB16 were changed from  to Skeletal defects, genital hypoplasia, and mental retardation, OMIM #612447","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:23:45.313728+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1620","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ZBTB16 were set to ","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:23:30.800503+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1619","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ZBTB16 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:23:13.746358+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1618","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ZBTB16 as Amber List (moderate evidence)","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:23:13.737584+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1618","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zbtb16 has been classified as Amber List (Moderate Evidence).","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:22:52.410702+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1617","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ZBTB16: Rating: AMBER; Mode of pathogenicity: None; Publications: 18611983; Phenotypes: Skeletal defects, genital hypoplasia, and mental retardation, OMIM #612447; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:22:06.814316+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2368","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ZBTB16 as ready","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:22:06.805224+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2368","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zbtb16 has been classified as Amber List (Moderate Evidence).","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:22:01.744257+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2368","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ZBTB16 were changed from  to Skeletal defects, genital hypoplasia, and mental retardation, OMIM #612447","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:21:34.377572+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2367","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ZBTB16 were set to ","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:21:04.712946+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2366","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ZBTB16 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ZBTB16","entity_type":"gene"},{"created":"2020-03-04T11:19:12.363414+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1617","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ZBTB11 as ready","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:19:12.350042+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1617","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zbtb11 has been classified as Amber List (Moderate Evidence).","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:19:04.643977+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1617","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ZBTB11 were changed from  to Intellectual developmental disorder, autosomal recessive 69, OMIM #618383","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:18:42.298984+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1616","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ZBTB11 were set to ","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:18:29.125572+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1615","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ZBTB11 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:18:03.488888+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1614","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ZBTB11 as Amber List (moderate evidence)","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:18:03.480162+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1614","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zbtb11 has been classified as Amber List (Moderate Evidence).","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:17:39.233773+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1613","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ZBTB11: Rating: AMBER; Mode of pathogenicity: None; Publications: 29893856; Phenotypes: Intellectual developmental disorder, autosomal recessive 69, OMIM #618383; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:16:51.547314+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2365","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ZBTB11 as ready","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:16:51.532505+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2365","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zbtb11 has been classified as Amber List (Moderate Evidence).","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:16:43.646353+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2365","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ZBTB11 were changed from  to Intellectual developmental disorder, autosomal recessive 69; OMIM #618383","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:16:11.166829+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2364","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ZBTB11 were set to ","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:15:38.630743+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2363","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ZBTB11 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ZBTB11","entity_type":"gene"},{"created":"2020-03-04T11:13:51.393728+11:00","panel_name":"Anophthalmia_Microphthalmia_Coloboma","panel_id":42,"panel_version":"0.49","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: YAP1 were set to ","entity_name":"YAP1","entity_type":"gene"},{"created":"2020-03-04T11:13:17.452124+11:00","panel_name":"Anophthalmia_Microphthalmia_Coloboma","panel_id":42,"panel_version":"0.48","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: YAP1: Added comment: Four families reported; incomplete penetrance and variable expressivity.; Changed publications: 24462371, 27267789, 28801591","entity_name":"YAP1","entity_type":"gene"},{"created":"2020-03-04T11:04:36.465996+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2362","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: XPA were set to ","entity_name":"XPA","entity_type":"gene"},{"created":"2020-03-04T11:03:53.033047+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2361","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: XPA: Rating: GREEN; Mode of pathogenicity: None; Publications: 26302748, 25566891, 24135642; Phenotypes: Xeroderma pigmentosum, group A, OMIM# 278700; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"XPA","entity_type":"gene"},{"created":"2020-03-04T10:49:20.486723+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.2361","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: WNT5A: Rating: GREEN; Mode of pathogenicity: None; Publications: 17256787; Phenotypes: Robinow syndrome, autosomal dominant 1, OMIM# 180700; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"WNT5A","entity_type":"gene"},{"created":"2020-03-04T10:44:16.258623+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1613","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: WNT3 as ready","entity_name":"WNT3","entity_type":"gene"},{"created":"2020-03-04T10:44:16.249078+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.1613","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: wnt3 has been classified as Red List (Low Evidence).","entity_name":"WNT3","entity_type":"gene"}]}