{"count":220917,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1960","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1958","results":[{"created":"2020-01-26T21:44:11.742016+11:00","panel_name":"Ciliary Dyskinesia","panel_id":82,"panel_version":"0.17","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TTC12 as Green List (high evidence)","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:44:11.734546+11:00","panel_name":"Ciliary Dyskinesia","panel_id":82,"panel_version":"0.17","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ttc12 has been classified as Green List (High Evidence).","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:44:05.082501+11:00","panel_name":"Ciliary Dyskinesia","panel_id":82,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TTC12 as ready","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:44:05.074346+11:00","panel_name":"Ciliary Dyskinesia","panel_id":82,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ttc12 has been classified as Green List (High Evidence).","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:43:48.013797+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.974","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TTC12 as ready","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:43:47.299587+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.974","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ttc12 has been classified as Green List (High Evidence).","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:43:35.579077+11:00","panel_name":"Ciliary Dyskinesia","panel_id":82,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TTC12 as Green List (high evidence)","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:43:35.572299+11:00","panel_name":"Ciliary Dyskinesia","panel_id":82,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ttc12 has been classified as Green List (High Evidence).","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:43:16.510752+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.974","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TTC12 as Green List (high evidence)","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:43:16.502228+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.974","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ttc12 has been classified as Green List (High Evidence).","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:42:42.252623+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.973","user_name":"Zornitza Stark","item_type":"entity","text":"gene: TTC12 was added\ngene: TTC12 was added to Mendeliome. Sources: Literature\nMode of inheritance for gene: TTC12 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: TTC12 were set to 31978331\nPhenotypes for gene: TTC12 were set to Ciliary dyskinesia\nReview for gene: TTC12 was set to GREEN\nAdded comment: Four unrelated families reported, LoF variants, respiratory phenotype. \nSources: Literature","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:41:04.135656+11:00","panel_name":"Ciliary Dyskinesia","panel_id":82,"panel_version":"0.15","user_name":"Zornitza Stark","item_type":"entity","text":"gene: TTC12 was added\ngene: TTC12 was added to Ciliary Dyskinesia. Sources: Literature\nMode of inheritance for gene: TTC12 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: TTC12 were set to 31978331\nPhenotypes for gene: TTC12 were set to Ciliary dyskinesia\nReview for gene: TTC12 was set to GREEN\nAdded comment: Four unrelated families with LoF variants reported with a respiratory phenotype. \nSources: Literature","entity_name":"TTC12","entity_type":"gene"},{"created":"2020-01-26T21:07:36.157080+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1702","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC6A9 as ready","entity_name":"SLC6A9","entity_type":"gene"},{"created":"2020-01-26T21:07:36.149261+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1702","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc6a9 has been classified as Green List (High Evidence).","entity_name":"SLC6A9","entity_type":"gene"},{"created":"2020-01-26T21:07:26.385276+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1702","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SLC6A9 were changed from Glycine encephalopathy with normal serum glycine 617301 to Glycine encephalopathy with normal serum glycine 617301","entity_name":"SLC6A9","entity_type":"gene"},{"created":"2020-01-26T21:06:43.617574+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1701","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SLC6A9 were changed from  to Glycine encephalopathy with normal serum glycine 617301","entity_name":"SLC6A9","entity_type":"gene"},{"created":"2020-01-26T21:06:08.391710+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1701","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SLC6A9 were set to ","entity_name":"SLC6A9","entity_type":"gene"},{"created":"2020-01-26T21:05:33.009861+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1700","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SLC6A9 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLC6A9","entity_type":"gene"},{"created":"2020-01-26T21:04:46.923007+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1699","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SLC6A9: Rating: GREEN; Mode of pathogenicity: None; Publications: 27481395, 27773429; Phenotypes: Glycine encephalopathy with normal serum glycine 617301; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal; Current diagnostic: yes","entity_name":"SLC6A9","entity_type":"gene"},{"created":"2020-01-26T21:02:29.772597+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.972","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: GCSH as ready","entity_name":"GCSH","entity_type":"gene"},{"created":"2020-01-26T21:02:29.765292+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.972","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: gcsh has been classified as Red List (Low Evidence).","entity_name":"GCSH","entity_type":"gene"},{"created":"2020-01-26T21:02:20.518013+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.972","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: GCSH were changed from  to Glycine encephalopathy, MIM# 605899","entity_name":"GCSH","entity_type":"gene"},{"created":"2020-01-26T21:02:02.478364+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1699","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: DHFR as ready","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T21:02:02.471093+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1699","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: dhfr has been classified as Green List (High Evidence).","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T21:00:16.936905+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.971","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: STT3B as ready","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T21:00:16.929079+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.971","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: stt3b has been classified as Red List (Low Evidence).","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T21:00:07.888352+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.971","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: GCSH were set to ","entity_name":"GCSH","entity_type":"gene"},{"created":"2020-01-26T20:59:51.095683+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.970","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: GCSH was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"GCSH","entity_type":"gene"},{"created":"2020-01-26T20:59:32.356754+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.969","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: GCSH as Red List (low evidence)","entity_name":"GCSH","entity_type":"gene"},{"created":"2020-01-26T20:59:32.348599+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.969","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: gcsh has been classified as Red List (Low Evidence).","entity_name":"GCSH","entity_type":"gene"},{"created":"2020-01-26T20:59:12.631624+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.968","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: GCSH: Rating: RED; Mode of pathogenicity: None; Publications: 1671321; Phenotypes: Glycine encephalopathy, MIM# 605899; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"GCSH","entity_type":"gene"},{"created":"2020-01-26T20:58:07.114683+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1699","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: DHFR were changed from  to Megaloblastic anemia due to dihydrofolate reductase deficiency, MIM# 613839","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:56:42.569504+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.549","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: DHFR as ready","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:56:42.561947+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.549","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: dhfr has been classified as Amber List (Moderate Evidence).","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:54:01.451392+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.549","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: DHFR as Amber List (moderate evidence)","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:54:01.443592+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.549","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: dhfr has been classified as Amber List (Moderate Evidence).","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:53:53.386519+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.968","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: STT3B were set to 23842455","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:53:03.001013+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.548","user_name":"Zornitza Stark","item_type":"entity","text":"gene: DHFR was added\ngene: DHFR was added to Genetic Epilepsy. Sources: Expert Review\nMode of inheritance for gene: DHFR was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: DHFR were set to 21310276; 21310277\nPhenotypes for gene: DHFR were set to Megaloblastic anemia due to dihydrofolate reductase deficiency, MIM# 613839\nReview for gene: DHFR was set to AMBER\nAdded comment: Three unrelated families reported, neurological disease in some severe (including seizures), others predominantly haematological presentation. \nSources: Expert Review","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:51:35.927035+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1698","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: DHFR were set to ","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:50:11.731422+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1697","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: DHFR was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:49:23.945748+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1696","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: DHFR: Rating: GREEN; Mode of pathogenicity: None; Publications: 21310276, 21310277; Phenotypes: Megaloblastic anemia due to dihydrofolate reductase deficiency, MIM# 613839; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"DHFR","entity_type":"gene"},{"created":"2020-01-26T20:44:35.980015+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.967","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: STT3B was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:44:13.542522+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.966","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: STT3B were set to ","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:43:57.407908+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.29","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: STT3B as ready","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:43:57.399429+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.29","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: stt3b has been classified as Red List (Low Evidence).","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:43:54.592945+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.965","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: STT3B were changed from  to Congenital disorder of glycosylation, type Ix 615597","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:41:49.837210+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.29","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: STT3B was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:41:18.361934+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.29","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: STT3B were changed from Congenital disorder of glycosylation, type Ix 615597 to Congenital disorder of glycosylation, type Ix 615597","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:40:57.361421+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.964","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: STT3B as Red List (low evidence)","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:40:56.572838+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.964","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: stt3b has been classified as Red List (Low Evidence).","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:40:45.297073+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: STT3B were changed from  to Congenital disorder of glycosylation, type Ix 615597","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:40:13.474942+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: STT3B were set to ","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:39:57.882527+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.963","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: STT3B: Rating: RED; Mode of pathogenicity: None; Publications: 23842455; Phenotypes: Congenital disorder of glycosylation, type Ix 615597; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:39:09.548209+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1696","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SLC39A8 were changed from Congenital disorder of glycosylation, type IIn , MIM#16721 to Congenital disorder of glycosylation, type IIn , MIM#16721","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:38:48.125392+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1695","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC39A8 as ready","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:38:48.117097+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1695","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc39a8 has been classified as Green List (High Evidence).","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:38:42.022131+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.27","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: STT3B as Red List (low evidence)","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:38:40.664746+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.27","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: stt3b has been classified as Red List (Low Evidence).","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:37:54.478389+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: STT3B: Rating: RED; Mode of pathogenicity: None; Publications: 23842455; Phenotypes: Congenital disorder of glycosylation, type Ix 615597; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"STT3B","entity_type":"gene"},{"created":"2020-01-26T20:35:26.564764+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.963","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC39A8 as ready","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:35:26.557210+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.963","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc39a8 has been classified as Green List (High Evidence).","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:33:59.463943+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.547","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC39A8 as ready","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:33:59.457208+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.547","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc39a8 has been classified as Green List (High Evidence).","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:32:13.318353+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.963","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SLC39A8 were changed from  to Congenital disorder of glycosylation, type IIn , MIM#16721","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:32:12.523826+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.547","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SLC39A8 as Green List (high evidence)","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:32:12.515653+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.547","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc39a8 has been classified as Green List (High Evidence).","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:31:50.449688+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.962","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SLC39A8 were set to ","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:31:11.379078+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.961","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SLC39A8 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:31:09.586159+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.546","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SLC39A8 was added\ngene: SLC39A8 was added to Genetic Epilepsy. Sources: Expert Review\nMode of inheritance for gene: SLC39A8 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: SLC39A8 were set to 26637978; 26637979\nPhenotypes for gene: SLC39A8 were set to Congenital disorder of glycosylation, type IIn , MIM#16721\nReview for gene: SLC39A8 was set to GREEN\nAdded comment: 6 individuals from Hutterite descent and two other unrelated families reported. Seizures reported in 2 Hutterite individuals and also in the other two unrelated families. \nSources: Expert Review","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:28:59.453809+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.545","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-26T20:28:53.725621+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC39A8 as ready","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:28:53.717105+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc39a8 has been classified as Green List (High Evidence).","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:28:40.130208+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SLC39A8 as Green List (high evidence)","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:28:39.922040+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc39a8 has been classified as Green List (High Evidence).","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:28:14.026421+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1695","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SLC39A8 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:27:52.409677+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SLC39A8 was added\ngene: SLC39A8 was added to Congenital Disorders of Glycosylation. Sources: Expert Review\nMode of inheritance for gene: SLC39A8 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: SLC39A8 were set to 26637978; 26637979\nPhenotypes for gene: SLC39A8 were set to Congenital disorder of glycosylation, type IIn , MIM#16721\nReview for gene: SLC39A8 was set to GREEN\ngene: SLC39A8 was marked as current diagnostic\nAdded comment: 6 individuals from Hutterite descent and two other unrelated families reported. \nSources: Expert Review","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:27:40.137731+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1694","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SLC39A8 were changed from  to Congenital disorder of glycosylation, type IIn , MIM#16721","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:26:48.776966+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1694","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SLC39A8 were set to ","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:24:56.191081+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1693","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SLC39A8: Rating: GREEN; Mode of pathogenicity: None; Publications: 26637978, 26637979; Phenotypes: Congenital disorder of glycosylation, type IIn , MIM#16721; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLC39A8","entity_type":"gene"},{"created":"2020-01-26T20:22:02.060478+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.544","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC35A3 as ready","entity_name":"SLC35A3","entity_type":"gene"},{"created":"2020-01-26T20:22:02.052608+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.544","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc35a3 has been classified as Amber List (Moderate Evidence).","entity_name":"SLC35A3","entity_type":"gene"},{"created":"2020-01-26T20:21:35.265483+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.544","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SLC35A3 as Amber List (moderate evidence)","entity_name":"SLC35A3","entity_type":"gene"},{"created":"2020-01-26T20:21:35.258418+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.544","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc35a3 has been classified as Amber List (Moderate Evidence).","entity_name":"SLC35A3","entity_type":"gene"},{"created":"2020-01-26T20:20:32.833261+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.543","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SLC35A3 was added\ngene: SLC35A3 was added to Genetic Epilepsy. Sources: Expert Review\nMode of inheritance for gene: SLC35A3 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: SLC35A3 were set to 28328131; 24031089; 28777481\nPhenotypes for gene: SLC35A3 were set to Arthrogryposis, mental retardation, and seizures; OMIM #615553\nReview for gene: SLC35A3 was set to AMBER\nAdded comment: Three families reported; seizures in two. \nSources: Expert Review","entity_name":"SLC35A3","entity_type":"gene"},{"created":"2020-01-26T19:53:39.479677+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.542","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC35A1 as ready","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:53:39.469302+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.542","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc35a1 has been classified as Amber List (Moderate Evidence).","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:53:17.596535+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.24","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SLC35A1 as ready","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:53:17.589591+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.24","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc35a1 has been classified as Green List (High Evidence).","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:51:33.061278+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.24","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PGM1 as ready","entity_name":"PGM1","entity_type":"gene"},{"created":"2020-01-26T19:51:33.052761+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.24","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pgm1 has been classified as Green List (High Evidence).","entity_name":"PGM1","entity_type":"gene"},{"created":"2020-01-26T19:49:23.556698+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.24","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PGM1 were changed from  to Congenital disorder of glycosylation, type It 614921","entity_name":"PGM1","entity_type":"gene"},{"created":"2020-01-26T19:49:00.915640+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.542","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: SLC35A1 as Amber List (moderate evidence)","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:49:00.136631+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.542","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: slc35a1 has been classified as Amber List (Moderate Evidence).","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:47:57.467281+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.541","user_name":"Zornitza Stark","item_type":"entity","text":"gene: SLC35A1 was added\ngene: SLC35A1 was added to Genetic Epilepsy. Sources: Expert Review\nMode of inheritance for gene: SLC35A1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: SLC35A1 were set to 28856833; 23873973; 11157507\nPhenotypes for gene: SLC35A1 were set to Congenital disorder of glycosylation, type IIf, MIM# 603585\nReview for gene: SLC35A1 was set to AMBER\nAdded comment: Three unrelated families reported, neurological presentation including seizures in two. \nSources: Expert Review","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:47:03.797321+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.23","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SLC35A1 were changed from  to Congenital disorder of glycosylation, type IIf, MIM# 603585","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:45:51.471636+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.22","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SLC35A1 were set to ","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:45:36.841049+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1693","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PIGS as ready","entity_name":"PIGS","entity_type":"gene"},{"created":"2020-01-26T19:45:36.832290+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1693","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pigs has been classified as Green List (High Evidence).","entity_name":"PIGS","entity_type":"gene"},{"created":"2020-01-26T19:45:16.012352+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SLC35A1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLC35A1","entity_type":"gene"},{"created":"2020-01-26T19:44:33.213436+11:00","panel_name":"Congenital Disorders of Glycosylation","panel_id":68,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SLC35A1: Rating: GREEN; Mode of pathogenicity: None; Publications: 28856833, 23873973, 11157507; Phenotypes: Congenital disorder of glycosylation, type IIf, MIM# 603585; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"SLC35A1","entity_type":"gene"}]}