{"count":220790,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1982","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=1980","results":[{"created":"2020-01-16T10:05:05.451206+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.798","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TET3 as Green List (high evidence)","entity_name":"TET3","entity_type":"gene"},{"created":"2020-01-16T10:05:05.443808+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.798","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tet3 has been classified as Green List (High Evidence).","entity_name":"TET3","entity_type":"gene"},{"created":"2020-01-16T10:04:44.015466+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.797","user_name":"Zornitza Stark","item_type":"entity","text":"gene: TET3 was added\ngene: TET3 was added to Mendeliome. Sources: Literature\nMode of inheritance for gene: TET3 was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal\nPublications for gene: TET3 were set to 31928709\nPhenotypes for gene: TET3 were set to Intellectual disability; dysmorphic features; abnormal growth; movement disorders\nReview for gene: TET3 was set to GREEN\nAdded comment: Eleven individuals from 8 families described. Mono-allelic frameshift and nonsense variants occur throughout the coding region. Mono-allelic and bi-allelic missense variants localize to conserved residues; all but one such variant occur within the catalytic domain, and most display hypomorphic function in an assay of catalytic activity. \nSources: Literature","entity_name":"TET3","entity_type":"gene"},{"created":"2020-01-16T10:02:21.598402+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.796","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T10:00:52.062059+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1599","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TET3 as ready","entity_name":"TET3","entity_type":"gene"},{"created":"2020-01-16T10:00:52.054789+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1599","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tet3 has been classified as Green List (High Evidence).","entity_name":"TET3","entity_type":"gene"},{"created":"2020-01-16T10:00:09.896912+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1599","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TET3 as Green List (high evidence)","entity_name":"TET3","entity_type":"gene"},{"created":"2020-01-16T10:00:09.889399+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1599","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tet3 has been classified as Green List (High Evidence).","entity_name":"TET3","entity_type":"gene"},{"created":"2020-01-16T09:59:32.028089+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1598","user_name":"Zornitza Stark","item_type":"entity","text":"gene: TET3 was added\ngene: TET3 was added to Intellectual disability syndromic and non-syndromic. Sources: Literature\nMode of inheritance for gene: TET3 was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal\nPublications for gene: TET3 were set to 31928709\nPhenotypes for gene: TET3 were set to Intellectual disability; dysmorphic features; abnormal growth; movement disorders\nReview for gene: TET3 was set to GREEN\nAdded comment: Eleven individuals from 8 families described. Mono-allelic frameshift and nonsense variants occur throughout the coding region. Mono-allelic and bi-allelic missense variants localize to conserved residues; all but one such variant occur within the catalytic domain, and most display hypomorphic function in an assay of catalytic activity. \nSources: Literature","entity_name":"TET3","entity_type":"gene"},{"created":"2020-01-16T09:18:05.589475+11:00","panel_name":"Cholestasis","panel_id":78,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T09:15:55.746874+11:00","panel_name":"Channelopathy","panel_id":74,"panel_version":"0.5","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T09:15:07.052530+11:00","panel_name":"Cerebral Palsy","panel_id":73,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T09:13:03.157128+11:00","panel_name":"Cerebellar and Pontocerebellar Hypoplasia","panel_id":72,"panel_version":"0.9","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Cerebellar and Pontocerebellar hypoplasia to Cerebellar and Pontocerebellar Hypoplasia\nPanel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T09:12:16.597941+11:00","panel_name":"Central Hypoventilation","panel_id":71,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T09:11:29.421288+11:00","panel_name":"Catecholaminergic Polymorphic Ventricular Tachycardia","panel_id":92,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T09:10:39.618533+11:00","panel_name":"Cardiomyopathy_SuperPanel","panel_id":253,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Superpanel; Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T07:13:14.423958+11:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Australian Genomics; Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-16T07:12:30.866627+11:00","panel_name":"Lissencephaly and Band Heterotopia","panel_id":15,"panel_version":"0.9","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Lissencephaly and band heterotopia to Lissencephaly and Band Heterotopia","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:48:46.453233+11:00","panel_name":"Renal Tubulointerstitial Disease","panel_id":199,"panel_version":"0.9","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; KidGen; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:46:58.253098+11:00","panel_name":"Renal Macrocystic Disease","panel_id":194,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; KidGen; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:45:56.025292+11:00","panel_name":"Renal Ciliopathies and Nephronophthisis","panel_id":193,"panel_version":"0.94","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; KidGen; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:41:04.051310+11:00","panel_name":"Cancer Predisposition_Paediatric","panel_id":152,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:40:10.847937+11:00","panel_name":"Callosome","panel_id":205,"panel_version":"0.57","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:38:58.216036+11:00","panel_name":"Brugada syndrome","panel_id":60,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:36:06.878188+11:00","panel_name":"Brain Calcification","panel_id":58,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Brain calcification to Brain Calcification\nPanel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:35:12.806870+11:00","panel_name":"Bone Marrow Failure","panel_id":56,"panel_version":"0.23","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:34:27.473788+11:00","panel_name":"Blepharophimosis","panel_id":55,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:33:37.173646+11:00","panel_name":"Bleeding Disorders","panel_id":54,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:31:42.122672+11:00","panel_name":"Bardet Biedl syndrome","panel_id":53,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:30:52.267219+11:00","panel_name":"Autism","panel_id":51,"panel_version":"0.38","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:30:10.789967+11:00","panel_name":"Atypical Haemolytic Uraemic Syndrome_MPGN","panel_id":211,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; KidGen; Royal Melbourne Hospital; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:28:52.039605+11:00","panel_name":"Atrial Fibrillation","panel_id":210,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Atrial fibrillation to Atrial Fibrillation\nPanel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:17:25.197830+11:00","panel_name":"Arthrogryposis","panel_id":47,"panel_version":"0.15","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:16:42.303365+11:00","panel_name":"Arrhythmogenic Right Ventricular Cardiomyopathy","panel_id":48,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:14:06.940489+11:00","panel_name":"Arrhythmia_SuperPanel","panel_id":254,"panel_version":"0.13","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Superpanel; Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:12:59.720970+11:00","panel_name":"Aortopathy_Connective Tissue Disorders","panel_id":44,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Aortopathy_Connective tissue disorders to Aortopathy_Connective Tissue Disorders\nPanel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:12:02.195671+11:00","panel_name":"Anophthalmia_Microphthalmia_Coloboma","panel_id":42,"panel_version":"0.40","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:10:49.345275+11:00","panel_name":"Angelman Rett like syndromes","panel_id":41,"panel_version":"0.5","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:09:24.281697+11:00","panel_name":"Alternating Hemiplegia and Hemiplegic Migraine","panel_id":40,"panel_version":"0.7","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T20:05:46.295335+11:00","panel_name":"Alagille syndrome","panel_id":36,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services; Rare Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T19:23:30.790953+11:00","panel_name":"Severe Combined Immunodeficiency (absent T present B cells)","panel_id":235,"panel_version":"0.6","user_name":"Sebastian Lunke","item_type":"panel","text":"Panel name changed from Severe Combined Immunodeficiency (absent T, present B cells) to Severe Combined Immunodeficiency (absent T present B cells)","entity_name":null,"entity_type":null},{"created":"2020-01-15T19:22:40.632871+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.1596","user_name":"Sebastian Lunke","item_type":"panel","text":"Panel name changed from Intellectual disability, syndromic and non-syndromic to Intellectual disability syndromic and non-syndromic","entity_name":null,"entity_type":null},{"created":"2020-01-15T18:05:20.621108+11:00","panel_name":"Alternating Hemiplegia and Hemiplegic Migraine","panel_id":40,"panel_version":"0.6","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Alternating hemiplegia including hemiplegic migraine to Alternating Hemiplegia and Hemiplegic Migraine","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:57:35.055675+11:00","panel_name":"Storage Disorder","panel_id":181,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Storage Disorder_VCGS to Storage Disorder\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:53:48.454235+11:00","panel_name":"Skeletal Dysplasia_Fetal","panel_id":28,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Skeletal dysplasia Fetal_MelbourneGenomics_VCGS to Skeletal Dysplasia_Fetal\nPanel types changed to Victorian Clinical Genetics Services; Melbourne Genomics","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:51:23.516159+11:00","panel_name":"Skeletal dysplasia","panel_id":258,"panel_version":"0.6","user_name":"Zornitza Stark","item_type":"panel","text":"Panel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:47:40.987859+11:00","panel_name":"Short Rib Polydactyly_Jeune Asphyxiating Thoracic Dystrophy","panel_id":179,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Short Rib Polydactyly, Jeune Asphyxiating Thoracic Dystrophy_VCGS to Short Rib Polydactyly_Jeune Asphyxiating Thoracic Dystrophy\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:46:34.995753+11:00","panel_name":"Short QT syndrome","panel_id":174,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Short QT syndrome_VCGS to Short QT syndrome\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:44:52.644429+11:00","panel_name":"Severe Combined Immunodeficiency (absent T, present B cells)","panel_id":235,"panel_version":"0.5","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Severe combined immunodeficiency (absent T, present B cells)_MelbourneGenomics_VCGS to Severe Combined Immunodeficiency (absent T, present B cells)\nPanel types changed to Victorian Clinical Genetics Services; Melbourne Genomics","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:36:47.995871+11:00","panel_name":"Renal Tubulointerstitial Disease","panel_id":199,"panel_version":"0.8","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Renal tubulointerstitial disease_KidGen_VCGS to Renal Tubulointerstitial Disease\nPanel types changed to Victorian Clinical Genetics Services; KidGen","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:34:17.338315+11:00","panel_name":"Renal Macrocystic Disease","panel_id":194,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Renal macrocystic disease_KidGen_VCGS to Renal Macrocystic Disease\nPanel types changed to Victorian Clinical Genetics Services; KidGen","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:33:17.157719+11:00","panel_name":"Renal Hypertension and Disorders of Aldosterone Metabolism","panel_id":190,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Renal hypertension and disorders of aldosterone metabolism_KidGen_VCGS to Renal Hypertension and Disorders of Aldosterone Metabolism\nPanel types changed to Victorian Clinical Genetics Services; KidGen","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:31:55.069687+11:00","panel_name":"Renal Glomerular Disease_SuperPanel","panel_id":262,"panel_version":"0.149","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Renal glomerular disease_SuperPanel_VCGS_KidGen to Renal Glomerular Disease_SuperPanel\nPanel types changed to Superpanel; Victorian Clinical Genetics Services; KidGen","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:31:22.048654+11:00","panel_name":"Renal Cystic Disease_SuperPanel","panel_id":263,"panel_version":"0.104","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Renal cystic disease_SuperPanel_KidGen_VCGS to Renal Cystic Disease_SuperPanel\nPanel types changed to Superpanel; Victorian Clinical Genetics Services; KidGen","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:31:01.060269+11:00","panel_name":"Renal Ciliopathies and Nephronophthisis","panel_id":193,"panel_version":"0.93","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Renal ciliopathies and nephronophthisis_KidGen_VCGS to Renal Ciliopathies and Nephronophthisis\nPanel types changed to Victorian Clinical Genetics Services; KidGen","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:30:03.200495+11:00","panel_name":"Renal Amyloidosis","panel_id":191,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Renal amyloidosis_KidGen_VCGS to Renal Amyloidosis\nPanel types changed to Victorian Clinical Genetics Services; KidGen","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:25:11.524011+11:00","panel_name":"Regression","panel_id":206,"panel_version":"0.60","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Regression_VCGS to Regression\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:24:23.589154+11:00","panel_name":"Rasopathy","panel_id":164,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Rasopathy_VCGS to Rasopathy\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:23:19.402349+11:00","panel_name":"Radial Ray Abnormalities","panel_id":163,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Radial Ray Abnormalities_VCGS to Radial Ray Abnormalities\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:22:16.925151+11:00","panel_name":"Pulmonary Fibrosis_Interstitial Lung Disease","panel_id":162,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Pulmonary Fibrosis_VCGS to Pulmonary Fibrosis_Interstitial Lung Disease\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:21:14.855763+11:00","panel_name":"Pseudohypoparathyroidism and Albright Hereditary Osteodystrophy","panel_id":161,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Pseudohypoparathyroidism, Albright Hereditary Osteodystrophy_VCGS to Pseudohypoparathyroidism and Albright Hereditary Osteodystrophy\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:19:49.650897+11:00","panel_name":"Proteinuria","panel_id":144,"panel_version":"0.100","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Proteinuria_VCGS_KidGen to Proteinuria\nPanel types changed to Victorian Clinical Genetics Services; KidGen","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:18:51.316389+11:00","panel_name":"Predominantly Antibody Deficiency","panel_id":222,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Predominantly antibody deficiency_MelbourneGenomics_VCGS to Predominantly Antibody Deficiency\nPanel types changed to Victorian Clinical Genetics Services; Melbourne Genomics","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:17:09.107470+11:00","panel_name":"Polymicrogyria and Schizencephaly","panel_id":18,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Polymicrogyria and schizencephaly_AustralianGenomics_VCGS to Polymicrogyria and Schizencephaly\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:14:02.744036+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ALMS1 as ready","entity_name":"ALMS1","entity_type":"gene"},{"created":"2020-01-15T17:14:02.734838+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: alms1 has been classified as Red List (Low Evidence).","entity_name":"ALMS1","entity_type":"gene"},{"created":"2020-01-15T17:13:59.064610+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: ALMS1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"ALMS1","entity_type":"gene"},{"created":"2020-01-15T17:13:27.211142+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ALMS1 were changed from  to Alstrom syndrome, MIM#203800","entity_name":"ALMS1","entity_type":"gene"},{"created":"2020-01-15T17:13:01.696124+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.17","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ALMS1 as Red List (low evidence)","entity_name":"ALMS1","entity_type":"gene"},{"created":"2020-01-15T17:13:01.688379+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.17","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: alms1 has been classified as Red List (Low Evidence).","entity_name":"ALMS1","entity_type":"gene"},{"created":"2020-01-15T17:12:25.332570+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: ALMS1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Alstrom syndrome, MIM#203800; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ALMS1","entity_type":"gene"},{"created":"2020-01-15T17:10:49.409675+11:00","panel_name":"Polydactyly","panel_id":159,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Polydactyly_VCGS to Polydactyly\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:09:28.586034+11:00","panel_name":"Pierre Robin Sequence","panel_id":160,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Pierre Robin sequence _VCGS to Pierre Robin Sequence\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:08:34.017640+11:00","panel_name":"Photosensitivity Syndromes","panel_id":156,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Photosensitivity syndromes_VCGS to Photosensitivity Syndromes\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:07:22.841526+11:00","panel_name":"Phagocyte Defects","panel_id":233,"panel_version":"0.5","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Phagocyte defects_MelbourneGenomics_VCGS to Phagocyte Defects\nPanel types changed to Victorian Clinical Genetics Services; Melbourne Genomics","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:06:02.912398+11:00","panel_name":"Peroxisomal Disorders","panel_id":155,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Peroxisomal Disorders_VCGS to Peroxisomal Disorders\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:05:07.082925+11:00","panel_name":"Periventricular Grey Matter Heterotopia","panel_id":19,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Periventricular grey matter heterotopia_AustralianGenomics_VCGS to Periventricular Grey Matter Heterotopia\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:03:48.081301+11:00","panel_name":"Paroxysmal Dyskinesia","panel_id":259,"panel_version":"0.6","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Paroxysmal dyskinesia_VCGS to Paroxysmal Dyskinesia\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:03:02.537331+11:00","panel_name":"Pancreatitis","panel_id":154,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Pancreatitis_VCGS to Pancreatitis\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:02:17.951798+11:00","panel_name":"Palmoplantar Keratoderma and Erythrokeratoderma","panel_id":153,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Palmoplantar keratoderma and erythrokeratoderma_VCGS to Palmoplantar Keratoderma and Erythrokeratoderma\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:01:22.380061+11:00","panel_name":"Overgrowth","panel_id":151,"panel_version":"0.8","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Overgrowth_VCGS to Overgrowth\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T17:00:28.716547+11:00","panel_name":"Osteopetrosis","panel_id":150,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Osteopetrosis_VCGS to Osteopetrosis\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:59:42.681035+11:00","panel_name":"Osteogenesis Imperfecta","panel_id":147,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Osteogenesis imperfecta_VCGS to Osteogenesis Imperfecta\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:58:55.223194+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"0.5","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Optic Atrophy_VCGS to Optic Atrophy\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:58:10.519574+11:00","panel_name":"Oligodontia","panel_id":148,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Oligodontia_VCGS to Oligodontia\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:57:19.197837+11:00","panel_name":"Ocular and Oculocutaneous Albinism","panel_id":37,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Ocular and oculocutaneous albinism_VCGS to Ocular and Oculocutaneous Albinism\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:54:25.906484+11:00","panel_name":"Neurotransmitter Defects","panel_id":145,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Neurotransmitter Defect_VCGS to Neurotransmitter Defects\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:53:22.741655+11:00","panel_name":"Motor Neuron Disease","panel_id":25,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Motor neuron disease_MND to Motor Neuron Disease","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:47:38.986506+11:00","panel_name":"Arrhythmogenic Right Ventricular Cardiomyopathy","panel_id":48,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Arrhythmogenic right ventricular cardiomyopathy_ARVC to Arrhythmogenic Right Ventricular Cardiomyopathy","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:45:47.056461+11:00","panel_name":"Catecholaminergic Polymorphic Ventricular Tachycardia","panel_id":92,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Catecholaminergic polymorphic ventricular tachycardia_CPVT to Catecholaminergic Polymorphic Ventricular Tachycardia","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:44:06.982938+11:00","panel_name":"Dilated Cardiomyopathy","panel_id":95,"panel_version":"0.7","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Dilated cardiomyopathy_DCM to Dilated Cardiomyopathy","entity_name":null,"entity_type":null},{"created":"2020-01-15T16:36:44.016007+11:00","panel_name":"Brugada syndrome","panel_id":60,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Brugada syndrome_VCGS to Brugada syndrome","entity_name":null,"entity_type":null},{"created":"2020-01-15T15:43:00.782912+11:00","panel_name":"Muscular dystrophy","panel_id":141,"panel_version":"0.6","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Muscular dystrophy_VCGS to Muscular dystrophy\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T15:42:01.922256+11:00","panel_name":"Multiple pterygium syndrome","panel_id":139,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Multiple pterygium syndromeVCGS to Multiple pterygium syndrome\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T15:41:19.971486+11:00","panel_name":"Motor neuron disease_MND","panel_id":25,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Motor neuron disease MND_MelbourneGenomics_VCGS to Motor neuron disease_MND\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T15:40:33.792687+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.39","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Mitochondrial_AustralianGenomics_VCGS to Mitochondrial disease\nPanel types changed to Victorian Clinical Genetics Services; Australian Genomics","entity_name":null,"entity_type":null},{"created":"2020-01-15T15:38:08.092676+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"0.70","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Microcephaly_VCGS to Microcephaly\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T15:37:30.113090+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"0.795","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Mendeliome_VCGS to Mendeliome","entity_name":null,"entity_type":null},{"created":"2020-01-15T15:35:31.384999+11:00","panel_name":"Mandibulofacial Acrofacial dysostosis","panel_id":136,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Mandibulofacial Acrofacial dysostosis_VCGS to Mandibulofacial Acrofacial dysostosis\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null},{"created":"2020-01-15T15:34:56.943013+11:00","panel_name":"Macrocephaly_Megalencephaly","panel_id":135,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Macrocephaly/Megalencephaly_VCGS to Macrocephaly_Megalencephaly\nPanel types changed to Victorian Clinical Genetics Services","entity_name":null,"entity_type":null}]}