{"count":220377,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2054","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2052","results":[{"created":"2019-12-10T07:52:37.081486+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1109","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RUBCN as ready","entity_name":"RUBCN","entity_type":"gene"},{"created":"2019-12-10T07:52:37.074416+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1109","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rubcn has been classified as Red List (Low Evidence).","entity_name":"RUBCN","entity_type":"gene"},{"created":"2019-12-10T07:52:30.298201+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1109","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RUBCN were changed from  to Spinocerebellar ataxia, autosomal recessive 15, MIM#615705","entity_name":"RUBCN","entity_type":"gene"},{"created":"2019-12-10T07:52:18.278694+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1108","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RUBCN were set to ","entity_name":"RUBCN","entity_type":"gene"},{"created":"2019-12-10T07:52:07.327014+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1107","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RUBCN as Red List (low evidence)","entity_name":"RUBCN","entity_type":"gene"},{"created":"2019-12-10T07:52:07.319550+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1107","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rubcn has been classified as Red List (Low Evidence).","entity_name":"RUBCN","entity_type":"gene"},{"created":"2019-12-10T07:51:54.280392+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1106","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RUBCN: Rating: RED; Mode of pathogenicity: None; Publications: 30237576, 20826435, 23728897; Phenotypes: Spinocerebellar ataxia, autosomal recessive 15, MIM#615705; Mode of inheritance: None","entity_name":"RUBCN","entity_type":"gene"},{"created":"2019-12-10T07:47:24.342187+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1106","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RTN4IP1 were changed from  to Optic atrophy 10 with or without ataxia, mental retardation, and seizures, MIM#616732","entity_name":"RTN4IP1","entity_type":"gene"},{"created":"2019-12-10T07:47:16.271174+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1105","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RTN4IP1 were set to ","entity_name":"RTN4IP1","entity_type":"gene"},{"created":"2019-12-10T07:47:07.920334+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1104","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RTN4IP1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RTN4IP1","entity_type":"gene"},{"created":"2019-12-10T07:46:53.842171+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1103","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RTN4IP1: Rating: GREEN; Mode of pathogenicity: None; Publications: 26593267; Phenotypes: Optic atrophy 10 with or without ataxia, mental retardation, and seizures, MIM#616732; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RTN4IP1","entity_type":"gene"},{"created":"2019-12-10T07:43:45.857917+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1103","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RPS28 as ready","entity_name":"RPS28","entity_type":"gene"},{"created":"2019-12-10T07:43:45.850650+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1103","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rps28 has been classified as Red List (Low Evidence).","entity_name":"RPS28","entity_type":"gene"},{"created":"2019-12-10T07:43:40.567807+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1103","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RPS28 were changed from  to Diamond Blackfan anemia 15 with mandibulofacial dysostosis, MIM#606164","entity_name":"RPS28","entity_type":"gene"},{"created":"2019-12-10T07:43:30.357683+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1102","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RPS28 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RPS28","entity_type":"gene"},{"created":"2019-12-10T07:43:19.391945+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1101","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RPS28 as Red List (low evidence)","entity_name":"RPS28","entity_type":"gene"},{"created":"2019-12-10T07:43:19.383674+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1101","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rps28 has been classified as Red List (Low Evidence).","entity_name":"RPS28","entity_type":"gene"},{"created":"2019-12-10T07:43:07.319582+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1100","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RPS28: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Diamond Blackfan anemia 15 with mandibulofacial dysostosis, MIM#606164; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RPS28","entity_type":"gene"},{"created":"2019-12-10T07:40:28.371402+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1100","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RPS19 as ready","entity_name":"RPS19","entity_type":"gene"},{"created":"2019-12-10T07:40:28.363949+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1100","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rps19 has been classified as Red List (Low Evidence).","entity_name":"RPS19","entity_type":"gene"},{"created":"2019-12-10T07:40:19.491381+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1100","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RPS19 were changed from  to Diamond-Blackfan anemia 1, MIM#105650","entity_name":"RPS19","entity_type":"gene"},{"created":"2019-12-10T07:40:13.266652+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1099","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RPS19 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RPS19","entity_type":"gene"},{"created":"2019-12-10T07:38:26.765969+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1098","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RPS19 as Red List (low evidence)","entity_name":"RPS19","entity_type":"gene"},{"created":"2019-12-10T07:38:26.758479+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1098","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rps19 has been classified as Red List (Low Evidence).","entity_name":"RPS19","entity_type":"gene"},{"created":"2019-12-10T07:38:13.370278+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1097","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RPS19: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Diamond-Blackfan anemia 1, MIM#105650; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RPS19","entity_type":"gene"},{"created":"2019-12-10T07:35:12.653723+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1097","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RPL11 as ready","entity_name":"RPL11","entity_type":"gene"},{"created":"2019-12-10T07:35:12.646156+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1097","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rpl11 has been classified as Red List (Low Evidence).","entity_name":"RPL11","entity_type":"gene"},{"created":"2019-12-10T07:35:06.236540+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1097","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RPL11 were changed from  to Diamond-Blackfan anemia 7, MIM#612562","entity_name":"RPL11","entity_type":"gene"},{"created":"2019-12-10T07:34:53.893904+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1096","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RPL11 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RPL11","entity_type":"gene"},{"created":"2019-12-10T07:34:47.446814+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1095","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RPL11 as Red List (low evidence)","entity_name":"RPL11","entity_type":"gene"},{"created":"2019-12-10T07:34:47.439252+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1095","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rpl11 has been classified as Red List (Low Evidence).","entity_name":"RPL11","entity_type":"gene"},{"created":"2019-12-10T07:34:35.239169+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1094","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RPL11: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Diamond-Blackfan anemia 7, MIM#612562; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RPL11","entity_type":"gene"},{"created":"2019-12-10T07:31:42.524469+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1094","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RORA as ready","entity_name":"RORA","entity_type":"gene"},{"created":"2019-12-10T07:31:42.516904+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1094","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rora has been classified as Green List (High Evidence).","entity_name":"RORA","entity_type":"gene"},{"created":"2019-12-10T07:31:35.404267+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1094","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RORA as Green List (high evidence)","entity_name":"RORA","entity_type":"gene"},{"created":"2019-12-10T07:31:35.396819+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1094","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rora has been classified as Green List (High Evidence).","entity_name":"RORA","entity_type":"gene"},{"created":"2019-12-10T07:31:22.958456+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1093","user_name":"Zornitza Stark","item_type":"entity","text":"gene: RORA was added\ngene: RORA was added to Intellectual disability, syndromic and non-syndromic_GHQ_VCGS. Sources: Expert list\nMode of inheritance for gene: RORA was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: RORA were set to 29656859\nPhenotypes for gene: RORA were set to Intellectual developmental disorder with or without epilepsy or cerebellar ataxia, MIM#618060\nMode of pathogenicity for gene: RORA was set to Other\nReview for gene: RORA was set to GREEN\nAdded comment: Eleven unrelated individuals with de novo variants in this gene; postulated that some variants exert dominant-negative effect resulting in a more severe phenotype than the LoF variants. \nSources: Expert list","entity_name":"RORA","entity_type":"gene"},{"created":"2019-12-10T06:38:51.995922+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1092","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RNU4ATAC as ready","entity_name":"RNU4ATAC","entity_type":"gene"},{"created":"2019-12-10T06:38:51.988343+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1092","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rnu4atac has been classified as Green List (High Evidence).","entity_name":"RNU4ATAC","entity_type":"gene"},{"created":"2019-12-10T06:38:33.856942+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1092","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RNU4ATAC were changed from  to Microcephalic osteodysplastic primordial dwarfism, type I, MIM#210710; Roifman syndrome, MIM#616651","entity_name":"RNU4ATAC","entity_type":"gene"},{"created":"2019-12-10T06:38:21.470315+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1091","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RNU4ATAC was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RNU4ATAC","entity_type":"gene"},{"created":"2019-12-10T06:38:04.127892+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1090","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RNU4ATAC: Rating: GREEN; Mode of pathogenicity: Other; Publications: ; Phenotypes: Microcephalic osteodysplastic primordial dwarfism, type I, MIM#210710, Roifman syndrome, MIM#616651; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RNU4ATAC","entity_type":"gene"},{"created":"2019-12-10T06:32:17.666900+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1090","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RMRP as ready","entity_name":"RMRP","entity_type":"gene"},{"created":"2019-12-10T06:32:17.659519+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1090","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rmrp has been classified as Amber List (Moderate Evidence).","entity_name":"RMRP","entity_type":"gene"},{"created":"2019-12-10T06:32:13.883442+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1090","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RMRP were changed from  to Anauxetic dysplasia 1, MIM#607095","entity_name":"RMRP","entity_type":"gene"},{"created":"2019-12-10T06:32:07.309708+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1089","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RMRP was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RMRP","entity_type":"gene"},{"created":"2019-12-10T06:31:01.555681+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1088","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RMRP as Amber List (moderate evidence)","entity_name":"RMRP","entity_type":"gene"},{"created":"2019-12-10T06:31:01.545007+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1088","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rmrp has been classified as Amber List (Moderate Evidence).","entity_name":"RMRP","entity_type":"gene"},{"created":"2019-12-10T06:30:49.160081+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1087","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RMRP: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: Anauxetic dysplasia 1, MIM#607095; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RMRP","entity_type":"gene"},{"created":"2019-12-10T06:25:24.438945+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1087","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RIN2 as ready","entity_name":"RIN2","entity_type":"gene"},{"created":"2019-12-10T06:25:24.431243+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1087","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rin2 has been classified as Red List (Low Evidence).","entity_name":"RIN2","entity_type":"gene"},{"created":"2019-12-10T06:25:20.329309+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1087","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RIN2 were changed from  to Macrocephaly, alopecia, cutis laxa, and scoliosis, MIM#613075","entity_name":"RIN2","entity_type":"gene"},{"created":"2019-12-10T06:25:12.709934+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1086","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RIN2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RIN2","entity_type":"gene"},{"created":"2019-12-10T06:24:15.818569+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1085","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RIN2 as Red List (low evidence)","entity_name":"RIN2","entity_type":"gene"},{"created":"2019-12-10T06:24:15.811055+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1085","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rin2 has been classified as Red List (Low Evidence).","entity_name":"RIN2","entity_type":"gene"},{"created":"2019-12-10T06:24:01.737566+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1084","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RIN2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Macrocephaly, alopecia, cutis laxa, and scoliosis, MIM#613075; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RIN2","entity_type":"gene"},{"created":"2019-12-10T06:18:52.121929+11:00","panel_name":"Genetic Epilepsy_AustralianGenomics_VCGS","panel_id":202,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RHOBTB2 as ready","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:18:52.114540+11:00","panel_name":"Genetic Epilepsy_AustralianGenomics_VCGS","panel_id":202,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rhobtb2 has been classified as Green List (High Evidence).","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:18:46.681337+11:00","panel_name":"Genetic Epilepsy_AustralianGenomics_VCGS","panel_id":202,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RHOBTB2 were changed from  to Epileptic encephalopathy, early infantile, 64, MIM#618004","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:18:25.967305+11:00","panel_name":"Genetic Epilepsy_AustralianGenomics_VCGS","panel_id":202,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RHOBTB2 were set to ","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:18:04.722735+11:00","panel_name":"Genetic Epilepsy_AustralianGenomics_VCGS","panel_id":202,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RHOBTB2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:17:28.235671+11:00","panel_name":"Genetic Epilepsy_AustralianGenomics_VCGS","panel_id":202,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RHOBTB2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29768694, 29276004; Phenotypes: Epileptic encephalopathy, early infantile, 64, MIM#618004; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:16:00.764835+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1084","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RHOBTB2 as ready","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:16:00.756718+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1084","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rhobtb2 has been classified as Green List (High Evidence).","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:15:53.199744+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1084","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RHOBTB2 as Green List (high evidence)","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:15:53.191874+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1084","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rhobtb2 has been classified as Green List (High Evidence).","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:15:39.650184+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1083","user_name":"Zornitza Stark","item_type":"entity","text":"gene: RHOBTB2 was added\ngene: RHOBTB2 was added to Intellectual disability, syndromic and non-syndromic_GHQ_VCGS. Sources: Literature\nMode of inheritance for gene: RHOBTB2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: RHOBTB2 were set to 29768694; 29276004\nPhenotypes for gene: RHOBTB2 were set to Epileptic encephalopathy, early infantile, 64, MIM#618004\nReview for gene: RHOBTB2 was set to GREEN\nAdded comment: 13 individuals from unrelated families reported in the literature in 2018 with de novo variants in this gene and ID/EE. \nSources: Literature","entity_name":"RHOBTB2","entity_type":"gene"},{"created":"2019-12-10T06:10:24.156069+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1082","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RFX6 as ready","entity_name":"RFX6","entity_type":"gene"},{"created":"2019-12-10T06:10:24.091221+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1082","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rfx6 has been classified as Red List (Low Evidence).","entity_name":"RFX6","entity_type":"gene"},{"created":"2019-12-10T06:10:17.439826+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1082","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RFX6 were changed from  to Mitchell-Riley syndrome, MIM#615710","entity_name":"RFX6","entity_type":"gene"},{"created":"2019-12-10T06:10:02.493840+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1081","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RFX6 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RFX6","entity_type":"gene"},{"created":"2019-12-10T06:09:54.763559+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1080","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RFX6 as Red List (low evidence)","entity_name":"RFX6","entity_type":"gene"},{"created":"2019-12-10T06:09:54.755449+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1080","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rfx6 has been classified as Red List (Low Evidence).","entity_name":"RFX6","entity_type":"gene"},{"created":"2019-12-10T06:08:34.310608+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1079","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RFX6: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Mitchell-Riley syndrome, MIM#615710; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RFX6","entity_type":"gene"},{"created":"2019-12-10T06:06:56.326676+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1079","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RET as ready","entity_name":"RET","entity_type":"gene"},{"created":"2019-12-10T06:06:56.319194+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1079","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ret has been classified as Red List (Low Evidence).","entity_name":"RET","entity_type":"gene"},{"created":"2019-12-10T06:06:42.745058+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1079","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RET were changed from  to Central hypoventilation syndrome, congenital, MIM#209880; Medullary thyroid carcinoma, MIM#155240; Multiple endocrine neoplasia IIA, MIM#171400; Multiple endocrine neoplasia IIB, MIM#162300","entity_name":"RET","entity_type":"gene"},{"created":"2019-12-10T06:06:30.286623+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1078","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RET was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RET","entity_type":"gene"},{"created":"2019-12-10T06:06:22.822357+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1077","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RET as Red List (low evidence)","entity_name":"RET","entity_type":"gene"},{"created":"2019-12-10T06:06:22.814886+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1077","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ret has been classified as Red List (Low Evidence).","entity_name":"RET","entity_type":"gene"},{"created":"2019-12-10T06:06:10.822315+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1076","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RET: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Central hypoventilation syndrome, congenital, MIM#209880, Medullary thyroid carcinoma, MIM#155240, Multiple endocrine neoplasia IIA, MIM#171400, Multiple endocrine neoplasia IIB, MIM#162300; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RET","entity_type":"gene"},{"created":"2019-12-10T06:02:46.595511+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1076","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RECQL4 as ready","entity_name":"RECQL4","entity_type":"gene"},{"created":"2019-12-10T06:02:46.588341+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1076","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: recql4 has been classified as Red List (Low Evidence).","entity_name":"RECQL4","entity_type":"gene"},{"created":"2019-12-10T06:02:41.650578+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1076","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RECQL4 were changed from  to Baller-Gerold syndrome, MIM#218600; RAPADILINO syndrome, MIM#266280; Rothmund-Thomson syndrome, type 2,MIM#268400","entity_name":"RECQL4","entity_type":"gene"},{"created":"2019-12-10T06:02:29.724497+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1075","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RECQL4 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RECQL4","entity_type":"gene"},{"created":"2019-12-10T06:02:19.008239+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1074","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RECQL4 as Red List (low evidence)","entity_name":"RECQL4","entity_type":"gene"},{"created":"2019-12-10T06:02:19.000824+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1074","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: recql4 has been classified as Red List (Low Evidence).","entity_name":"RECQL4","entity_type":"gene"},{"created":"2019-12-10T06:02:05.895951+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1073","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RECQL4: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Baller-Gerold syndrome, MIM#218600, RAPADILINO syndrome, MIM#266280, Rothmund-Thomson syndrome, type 2,MIM#268400; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"RECQL4","entity_type":"gene"},{"created":"2019-12-10T05:56:07.946976+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1073","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RBPJ as ready","entity_name":"RBPJ","entity_type":"gene"},{"created":"2019-12-10T05:56:07.939363+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1073","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rbpj has been classified as Red List (Low Evidence).","entity_name":"RBPJ","entity_type":"gene"},{"created":"2019-12-10T05:56:01.280323+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1073","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RBPJ were changed from  to Adams-Oliver syndrome 3, MIM#614814","entity_name":"RBPJ","entity_type":"gene"},{"created":"2019-12-10T05:55:49.905706+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1072","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RBPJ were set to ","entity_name":"RBPJ","entity_type":"gene"},{"created":"2019-12-10T05:55:36.736202+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1071","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RBPJ as Red List (low evidence)","entity_name":"RBPJ","entity_type":"gene"},{"created":"2019-12-10T05:55:36.729136+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1071","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rbpj has been classified as Red List (Low Evidence).","entity_name":"RBPJ","entity_type":"gene"},{"created":"2019-12-10T05:55:22.836372+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1070","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: RBPJ: Rating: RED; Mode of pathogenicity: None; Publications: 22883147, 29924900; Phenotypes: Adams-Oliver syndrome 3, MIM#614814; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"RBPJ","entity_type":"gene"},{"created":"2019-12-10T05:48:28.103199+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1070","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RBM8A as ready","entity_name":"RBM8A","entity_type":"gene"},{"created":"2019-12-10T05:48:28.094781+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1070","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rbm8a has been classified as Red List (Low Evidence).","entity_name":"RBM8A","entity_type":"gene"},{"created":"2019-12-10T05:48:23.599928+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1070","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RBM8A were changed from  to Thrombocytopenia-absent radius syndrome, MIM#274000","entity_name":"RBM8A","entity_type":"gene"},{"created":"2019-12-10T05:48:11.369061+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1069","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: RBM8A was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"RBM8A","entity_type":"gene"},{"created":"2019-12-10T05:48:00.116265+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.1068","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: RBM8A as Red List (low evidence)","entity_name":"RBM8A","entity_type":"gene"}]}