{"count":220377,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2059","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2057","results":[{"created":"2019-12-08T18:12:03.613523+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.915","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PCDH12 were set to ","entity_name":"PCDH12","entity_type":"gene"},{"created":"2019-12-08T18:11:50.000669+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.914","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PCDH12 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCDH12","entity_type":"gene"},{"created":"2019-12-08T18:11:35.859858+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.913","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PCDH12: Rating: GREEN; Mode of pathogenicity: None; Publications: 27164683, 30178464; Phenotypes: Diencephalic-mesencephalic junction dysplasia syndrome 1, MIM#251280; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCDH12","entity_type":"gene"},{"created":"2019-12-08T18:08:03.476767+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.913","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PCBD1 were changed from  to Hyperphenylalaninemia, BH4-deficient, D, MIM#264070","entity_name":"PCBD1","entity_type":"gene"},{"created":"2019-12-08T18:07:51.198552+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.912","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PCBD1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCBD1","entity_type":"gene"},{"created":"2019-12-08T18:07:44.039521+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.911","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: PCBD1 as Red List (low evidence)","entity_name":"PCBD1","entity_type":"gene"},{"created":"2019-12-08T18:07:44.030623+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.911","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pcbd1 has been classified as Red List (Low Evidence).","entity_name":"PCBD1","entity_type":"gene"},{"created":"2019-12-08T18:07:30.149891+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.910","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PCBD1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Hyperphenylalaninemia, BH4-deficient, D, MIM#264070; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PCBD1","entity_type":"gene"},{"created":"2019-12-08T18:05:55.422542+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.910","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PAX3 as ready","entity_name":"PAX3","entity_type":"gene"},{"created":"2019-12-08T18:05:55.415309+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.910","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pax3 has been classified as Red List (Low Evidence).","entity_name":"PAX3","entity_type":"gene"},{"created":"2019-12-08T18:05:50.905836+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.910","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PAX3 were changed from  to Craniofacial-deafness-hand syndrome, MIM#122880; Waardenburg syndrome, type 1, MIM#193500; Waardenburg syndrome, type 3, MIM#148820","entity_name":"PAX3","entity_type":"gene"},{"created":"2019-12-08T18:05:41.315023+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.909","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PAX3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PAX3","entity_type":"gene"},{"created":"2019-12-08T18:05:33.450326+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.908","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: PAX3 as Red List (low evidence)","entity_name":"PAX3","entity_type":"gene"},{"created":"2019-12-08T18:05:33.442899+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.908","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pax3 has been classified as Red List (Low Evidence).","entity_name":"PAX3","entity_type":"gene"},{"created":"2019-12-08T18:05:21.573142+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.907","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PAX3: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Craniofacial-deafness-hand syndrome, MIM#122880, Waardenburg syndrome, type 1, MIM#193500, Waardenburg syndrome, type 3, MIM#148820; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PAX3","entity_type":"gene"},{"created":"2019-12-08T18:02:54.214870+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.907","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PAX2 as ready","entity_name":"PAX2","entity_type":"gene"},{"created":"2019-12-08T18:02:54.204054+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.907","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pax2 has been classified as Red List (Low Evidence).","entity_name":"PAX2","entity_type":"gene"},{"created":"2019-12-08T18:02:50.173689+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.907","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PAX2 were changed from  to Papillorenal syndrome, MIM#120330","entity_name":"PAX2","entity_type":"gene"},{"created":"2019-12-08T18:02:39.172500+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.906","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PAX2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PAX2","entity_type":"gene"},{"created":"2019-12-08T18:02:32.225468+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.905","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: PAX2 as Red List (low evidence)","entity_name":"PAX2","entity_type":"gene"},{"created":"2019-12-08T18:02:32.218563+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.905","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pax2 has been classified as Red List (Low Evidence).","entity_name":"PAX2","entity_type":"gene"},{"created":"2019-12-08T18:02:19.155918+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.904","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PAX2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Papillorenal syndrome, MIM#120330; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PAX2","entity_type":"gene"},{"created":"2019-12-08T18:00:31.403829+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.904","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PANK2 as ready","entity_name":"PANK2","entity_type":"gene"},{"created":"2019-12-08T18:00:31.396155+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.904","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pank2 has been classified as Red List (Low Evidence).","entity_name":"PANK2","entity_type":"gene"},{"created":"2019-12-08T18:00:27.435328+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.904","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PANK2 were changed from  to Neurodegeneration with brain iron accumulation 1, MIM#234200","entity_name":"PANK2","entity_type":"gene"},{"created":"2019-12-08T18:00:15.290597+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.903","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PANK2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PANK2","entity_type":"gene"},{"created":"2019-12-08T18:00:04.149364+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.902","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: PANK2 as Red List (low evidence)","entity_name":"PANK2","entity_type":"gene"},{"created":"2019-12-08T18:00:04.141182+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.902","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pank2 has been classified as Red List (Low Evidence).","entity_name":"PANK2","entity_type":"gene"},{"created":"2019-12-08T17:59:50.275388+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.901","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PANK2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Neurodegeneration with brain iron accumulation 1, MIM#234200; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PANK2","entity_type":"gene"},{"created":"2019-12-08T17:57:07.907851+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.901","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PAM16 as ready","entity_name":"PAM16","entity_type":"gene"},{"created":"2019-12-08T17:57:07.900043+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.901","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pam16 has been classified as Green List (High Evidence).","entity_name":"PAM16","entity_type":"gene"},{"created":"2019-12-08T17:56:56.361979+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.901","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PAM16 were changed from  to Spondylometaphyseal dysplasia, Megarbane-Dagher-Melike type, MIM#613320","entity_name":"PAM16","entity_type":"gene"},{"created":"2019-12-08T17:56:44.726497+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.900","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PAM16 were set to ","entity_name":"PAM16","entity_type":"gene"},{"created":"2019-12-08T17:56:30.311450+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.899","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PAM16 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PAM16","entity_type":"gene"},{"created":"2019-12-08T17:56:07.698712+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.898","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PAM16: Rating: GREEN; Mode of pathogenicity: None; Publications: 24786642, 27354339; Phenotypes: Spondylometaphyseal dysplasia, Megarbane-Dagher-Melike type, MIM#613320; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"PAM16","entity_type":"gene"},{"created":"2019-12-08T17:51:01.704363+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.898","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PACS2 as ready","entity_name":"PACS2","entity_type":"gene"},{"created":"2019-12-08T17:51:01.696444+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.898","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pacs2 has been classified as Green List (High Evidence).","entity_name":"PACS2","entity_type":"gene"},{"created":"2019-12-08T17:50:56.032043+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.898","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PACS2 were changed from  to Epileptic encephalopathy, early infantile, 66, MIM#618067","entity_name":"PACS2","entity_type":"gene"},{"created":"2019-12-08T17:50:44.668615+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.897","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PACS2 were set to ","entity_name":"PACS2","entity_type":"gene"},{"created":"2019-12-08T17:50:34.659253+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.896","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PACS2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PACS2","entity_type":"gene"},{"created":"2019-12-08T17:50:19.881044+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.895","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: PACS2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29656858; Phenotypes: Epileptic encephalopathy, early infantile, 66, MIM#618067; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"PACS2","entity_type":"gene"},{"created":"2019-12-08T15:24:34.457199+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","panel_id":250,"panel_version":"0.895","user_name":"Zornitza Stark","item_type":"panel","text":"Panel name changed from Intellectual disability, syndromic and non-syndromic_GHQ to Intellectual disability, syndromic and non-syndromic_GHQ_VCGS","entity_name":null,"entity_type":null},{"created":"2019-12-08T15:16:41.927860+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NUP62 as Green List (high evidence)","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:16:41.920501+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nup62 has been classified as Green List (High Evidence).","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:16:16.317240+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NUP62 as Green List (high evidence)","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:16:16.308436+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nup62 has been classified as Green List (High Evidence).","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:16:12.166396+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NUP62 as ready","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:16:12.156206+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nup62 has been classified as Red List (Low Evidence).","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:15:46.992011+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"gene: NUP62 was added\ngene: NUP62 was added to Regression_VCGS. Sources: Expert Review\nMode of inheritance for gene: NUP62 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NUP62 were set to 16786527\nPhenotypes for gene: NUP62 were set to Striatonigral degeneration, infantile, MIM#271930\nReview for gene: NUP62 was set to GREEN\nAdded comment: Multiple affected individuals, variable age of onset, may be after a viral trigger. \nSources: Expert Review","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:14:52.557262+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.893","user_name":"Zornitza Stark","item_type":"entity","text":"Deleted their comment","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:14:24.374857+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.893","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NUP62 as ready","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:14:24.371728+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.893","user_name":"Zornitza Stark","item_type":"entity","text":"Added comment: Comment when marking as ready: Multiple affected individuals, age of onset variable, may be after viral trigger.","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:14:24.353497+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.893","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nup62 has been classified as Red List (Low Evidence).","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:14:02.738055+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.893","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NUP62 were set to ","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:12:21.140396+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.892","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NUP62 were changed from  to Striatonigral degeneration, infantile, MIM#271930","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:12:10.099840+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.891","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NUP62 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:12:03.103529+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.890","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NUP62 as Red List (low evidence)","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:12:03.095739+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.890","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nup62 has been classified as Red List (Low Evidence).","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:11:50.910829+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.889","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NUP62: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Striatonigral degeneration, infantile, MIM#271930; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"NUP62","entity_type":"gene"},{"created":"2019-12-08T15:08:51.302315+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.889","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NRXN2 as ready","entity_name":"NRXN2","entity_type":"gene"},{"created":"2019-12-08T15:08:51.294614+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.889","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nrxn2 has been classified as Red List (Low Evidence).","entity_name":"NRXN2","entity_type":"gene"},{"created":"2019-12-08T15:08:46.719405+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.889","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NRXN2 were changed from  to Autism","entity_name":"NRXN2","entity_type":"gene"},{"created":"2019-12-08T15:08:38.477149+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.888","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NRXN2 were set to ","entity_name":"NRXN2","entity_type":"gene"},{"created":"2019-12-08T15:08:31.878759+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.887","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NRXN2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NRXN2","entity_type":"gene"},{"created":"2019-12-08T15:08:11.800425+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.886","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NRXN2 as Red List (low evidence)","entity_name":"NRXN2","entity_type":"gene"},{"created":"2019-12-08T15:08:11.792545+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.886","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nrxn2 has been classified as Red List (Low Evidence).","entity_name":"NRXN2","entity_type":"gene"},{"created":"2019-12-08T15:08:00.433952+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.885","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NRXN2: Rating: RED; Mode of pathogenicity: None; Publications: 21424692, 30709877, 25745399; Phenotypes: Autism; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NRXN2","entity_type":"gene"},{"created":"2019-12-08T15:02:29.165127+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.885","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NR4A2 as ready","entity_name":"NR4A2","entity_type":"gene"},{"created":"2019-12-08T15:02:29.157899+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.885","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nr4a2 has been classified as Amber List (Moderate Evidence).","entity_name":"NR4A2","entity_type":"gene"},{"created":"2019-12-08T15:02:24.564310+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.885","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NR4A2 were changed from  to Intellectual disability; rolandic epilepsy; autism","entity_name":"NR4A2","entity_type":"gene"},{"created":"2019-12-08T15:02:16.333438+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.884","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NR4A2 were set to ","entity_name":"NR4A2","entity_type":"gene"},{"created":"2019-12-08T15:02:08.224523+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.883","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NR4A2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NR4A2","entity_type":"gene"},{"created":"2019-12-08T15:02:01.339505+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.882","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NR4A2 as Amber List (moderate evidence)","entity_name":"NR4A2","entity_type":"gene"},{"created":"2019-12-08T15:02:01.330715+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.882","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nr4a2 has been classified as Amber List (Moderate Evidence).","entity_name":"NR4A2","entity_type":"gene"},{"created":"2019-12-08T15:01:48.601874+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.881","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NR4A2: Rating: AMBER; Mode of pathogenicity: None; Publications: 31428396, 30504930, 29770430; Phenotypes: Intellectual disability, rolandic epilepsy, autism; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NR4A2","entity_type":"gene"},{"created":"2019-12-08T14:52:10.172288+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.881","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NIN as ready","entity_name":"NIN","entity_type":"gene"},{"created":"2019-12-08T14:52:10.164271+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.881","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nin has been classified as Red List (Low Evidence).","entity_name":"NIN","entity_type":"gene"},{"created":"2019-12-08T14:52:05.410146+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.881","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NIN were changed from  to Seckel syndrome 7, MIM#614851","entity_name":"NIN","entity_type":"gene"},{"created":"2019-12-08T14:51:55.233443+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.880","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NIN were set to ","entity_name":"NIN","entity_type":"gene"},{"created":"2019-12-08T14:51:42.128356+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.879","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NIN was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NIN","entity_type":"gene"},{"created":"2019-12-08T14:51:30.665827+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.878","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NIN as Red List (low evidence)","entity_name":"NIN","entity_type":"gene"},{"created":"2019-12-08T14:51:30.657067+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.878","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nin has been classified as Red List (Low Evidence).","entity_name":"NIN","entity_type":"gene"},{"created":"2019-12-08T14:46:29.163890+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NPR3 as ready","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:46:29.156857+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: npr3 has been classified as Green List (High Evidence).","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:46:25.184437+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NPR3 as Green List (high evidence)","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:46:25.177272+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: npr3 has been classified as Green List (High Evidence).","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:45:59.074647+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"gene: NPR3 was added\ngene: NPR3 was added to Aortopathy, Connective tissue disorder_VCGS. Sources: Literature\nMode of inheritance for gene: NPR3 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: NPR3 were set to 30032985\nPhenotypes for gene: NPR3 were set to Tall stature, skeletal abnormalities, aortic dilatation\nReview for gene: NPR3 was set to GREEN\nAdded comment: 4 individuals from three unrelated families. \nSources: Literature","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:43:27.616426+11:00","panel_name":"Overgrowth_VCGS","panel_id":151,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NPR3 as ready","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:43:27.608882+11:00","panel_name":"Overgrowth_VCGS","panel_id":151,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: npr3 has been classified as Green List (High Evidence).","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:43:14.525244+11:00","panel_name":"Overgrowth_VCGS","panel_id":151,"panel_version":"0.4","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NPR3 were changed from  to Tall stature, skeletal abnormalities, aortic dilatation","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:42:58.023519+11:00","panel_name":"Overgrowth_VCGS","panel_id":151,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NPR3 were set to ","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:42:41.415928+11:00","panel_name":"Overgrowth_VCGS","panel_id":151,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NPR3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T14:42:13.290129+11:00","panel_name":"Overgrowth_VCGS","panel_id":151,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NPR3: Rating: GREEN; Mode of pathogenicity: None; Publications: 30032985; Phenotypes: Tall stature, skeletal abnormalities, aortic dilatation; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"NPR3","entity_type":"gene"},{"created":"2019-12-08T08:03:48.832159+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.877","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NOTCH3 as ready","entity_name":"NOTCH3","entity_type":"gene"},{"created":"2019-12-08T08:03:48.825269+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.877","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: notch3 has been classified as Red List (Low Evidence).","entity_name":"NOTCH3","entity_type":"gene"},{"created":"2019-12-08T08:03:44.191229+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.877","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NOTCH3 were changed from  to Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1, MIM#125310","entity_name":"NOTCH3","entity_type":"gene"},{"created":"2019-12-08T08:03:27.616462+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.876","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NOTCH3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NOTCH3","entity_type":"gene"},{"created":"2019-12-08T08:03:14.872502+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.875","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: NOTCH3 as Red List (low evidence)","entity_name":"NOTCH3","entity_type":"gene"},{"created":"2019-12-08T08:03:14.865324+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.875","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: notch3 has been classified as Red List (Low Evidence).","entity_name":"NOTCH3","entity_type":"gene"},{"created":"2019-12-08T08:03:01.337276+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.874","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NOTCH3: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1, MIM#125310; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NOTCH3","entity_type":"gene"}]}