{"count":220363,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2067","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2065","results":[{"created":"2019-12-06T14:09:17.681939+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.600","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LYRM7 as ready","entity_name":"LYRM7","entity_type":"gene"},{"created":"2019-12-06T14:09:17.674267+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.600","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lyrm7 has been classified as Green List (High Evidence).","entity_name":"LYRM7","entity_type":"gene"},{"created":"2019-12-06T14:09:13.076329+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.600","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LYRM7 were changed from  to Mitochondrial complex III deficiency, nuclear type 8, MIM#615838","entity_name":"LYRM7","entity_type":"gene"},{"created":"2019-12-06T14:08:58.532862+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.599","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LYRM7 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LYRM7","entity_type":"gene"},{"created":"2019-12-06T14:08:44.914315+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.598","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LYRM7: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Mitochondrial complex III deficiency, nuclear type 8, MIM#615838; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LYRM7","entity_type":"gene"},{"created":"2019-12-06T13:44:33.110822+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.598","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LMNB1 as ready","entity_name":"LMNB1","entity_type":"gene"},{"created":"2019-12-06T13:44:33.103354+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.598","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lmnb1 has been classified as Red List (Low Evidence).","entity_name":"LMNB1","entity_type":"gene"},{"created":"2019-12-06T13:44:21.361266+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.598","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LMNB1 were changed from  to Leukodystrophy, adult-onset, autosomal dominant, MIM#169500","entity_name":"LMNB1","entity_type":"gene"},{"created":"2019-12-06T13:44:08.804601+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.597","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LMNB1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"LMNB1","entity_type":"gene"},{"created":"2019-12-06T13:43:51.447100+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.596","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: LMNB1 as Red List (low evidence)","entity_name":"LMNB1","entity_type":"gene"},{"created":"2019-12-06T13:43:51.440000+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.596","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lmnb1 has been classified as Red List (Low Evidence).","entity_name":"LMNB1","entity_type":"gene"},{"created":"2019-12-06T13:42:20.974591+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.595","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LMNB1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Leukodystrophy, adult-onset, autosomal dominant, MIM#169500; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"LMNB1","entity_type":"gene"},{"created":"2019-12-06T13:40:54.695548+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.595","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LMNA as ready","entity_name":"LMNA","entity_type":"gene"},{"created":"2019-12-06T13:40:54.688423+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.595","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lmna has been classified as Red List (Low Evidence).","entity_name":"LMNA","entity_type":"gene"},{"created":"2019-12-06T13:40:48.862188+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.595","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: LMNA as Red List (low evidence)","entity_name":"LMNA","entity_type":"gene"},{"created":"2019-12-06T13:40:48.851752+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.595","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lmna has been classified as Red List (Low Evidence).","entity_name":"LMNA","entity_type":"gene"},{"created":"2019-12-06T13:40:36.964669+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.594","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LMNA: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None","entity_name":"LMNA","entity_type":"gene"},{"created":"2019-12-06T13:36:05.188859+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.594","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LIPT1 as ready","entity_name":"LIPT1","entity_type":"gene"},{"created":"2019-12-06T13:36:05.181235+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.594","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lipt1 has been classified as Green List (High Evidence).","entity_name":"LIPT1","entity_type":"gene"},{"created":"2019-12-06T13:36:00.823390+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.594","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LIPT1 were changed from  to Lipoyltransferase 1 deficiency, MIM#616299","entity_name":"LIPT1","entity_type":"gene"},{"created":"2019-12-06T13:35:47.293017+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.593","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LIPT1 were set to ","entity_name":"LIPT1","entity_type":"gene"},{"created":"2019-12-06T13:35:34.292232+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.592","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LIPT1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LIPT1","entity_type":"gene"},{"created":"2019-12-06T13:35:21.119342+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.591","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LIPT1: Rating: GREEN; Mode of pathogenicity: None; Publications: 24341803, 24256811, 29681092; Phenotypes: Lipoyltransferase 1 deficiency, MIM#616299; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LIPT1","entity_type":"gene"},{"created":"2019-12-06T13:30:17.604358+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.591","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: LINGO1 as Amber List (moderate evidence)","entity_name":"LINGO1","entity_type":"gene"},{"created":"2019-12-06T13:30:17.597232+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.591","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lingo1 has been classified as Amber List (Moderate Evidence).","entity_name":"LINGO1","entity_type":"gene"},{"created":"2019-12-06T13:29:50.299605+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.590","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LINGO1 as ready","entity_name":"LINGO1","entity_type":"gene"},{"created":"2019-12-06T13:29:50.291540+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.590","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lingo1 has been classified as Green List (High Evidence).","entity_name":"LINGO1","entity_type":"gene"},{"created":"2019-12-06T13:29:44.095431+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.590","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: LINGO1 as Green List (high evidence)","entity_name":"LINGO1","entity_type":"gene"},{"created":"2019-12-06T13:29:44.088394+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.590","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lingo1 has been classified as Green List (High Evidence).","entity_name":"LINGO1","entity_type":"gene"},{"created":"2019-12-06T13:29:25.094513+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.589","user_name":"Zornitza Stark","item_type":"entity","text":"gene: LINGO1 was added\ngene: LINGO1 was added to Intellectual disability, syndromic and non-syndromic_GHQ. Sources: Expert list\nMode of inheritance for gene: LINGO1 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: LINGO1 were set to 28837161\nPhenotypes for gene: LINGO1 were set to Mental retardation, autosomal recessive 64, MIM#618103\nReview for gene: LINGO1 was set to GREEN\nAdded comment: Five individuals from two unrelated families, no functional evidence. \nSources: Expert list","entity_name":"LINGO1","entity_type":"gene"},{"created":"2019-12-06T13:15:00.552356+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.588","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LIAS as ready","entity_name":"LIAS","entity_type":"gene"},{"created":"2019-12-06T13:15:00.541466+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.588","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lias has been classified as Green List (High Evidence).","entity_name":"LIAS","entity_type":"gene"},{"created":"2019-12-06T13:14:55.945035+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.588","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LIAS were changed from  to Hyperglycinemia, lactic acidosis, and seizures, MIM#614462","entity_name":"LIAS","entity_type":"gene"},{"created":"2019-12-06T13:14:41.481774+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.587","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: LIAS were set to ","entity_name":"LIAS","entity_type":"gene"},{"created":"2019-12-06T13:14:29.600111+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.586","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LIAS was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LIAS","entity_type":"gene"},{"created":"2019-12-06T13:14:13.627374+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.585","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LIAS: Rating: GREEN; Mode of pathogenicity: None; Publications: 24334290, 22152680; Phenotypes: Hyperglycinemia, lactic acidosis, and seizures, MIM#614462; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LIAS","entity_type":"gene"},{"created":"2019-12-06T13:11:18.973687+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.585","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LGI4 as ready","entity_name":"LGI4","entity_type":"gene"},{"created":"2019-12-06T13:11:18.966481+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.585","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lgi4 has been classified as Red List (Low Evidence).","entity_name":"LGI4","entity_type":"gene"},{"created":"2019-12-06T13:11:12.838437+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.585","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LGI4 were changed from  to Arthrogryposis multiplex congenita, neurogenic, with myelin defect, MIM#617468","entity_name":"LGI4","entity_type":"gene"},{"created":"2019-12-06T13:11:01.086641+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.584","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LGI4 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LGI4","entity_type":"gene"},{"created":"2019-12-06T13:09:51.519681+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.583","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: LGI4 as Red List (low evidence)","entity_name":"LGI4","entity_type":"gene"},{"created":"2019-12-06T13:09:51.512131+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.583","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lgi4 has been classified as Red List (Low Evidence).","entity_name":"LGI4","entity_type":"gene"},{"created":"2019-12-06T13:09:38.700318+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.582","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LGI4: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Arthrogryposis multiplex congenita, neurogenic, with myelin defect, MIM#617468; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"LGI4","entity_type":"gene"},{"created":"2019-12-06T12:58:19.471056+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.582","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LBR as ready","entity_name":"LBR","entity_type":"gene"},{"created":"2019-12-06T12:58:19.463838+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.582","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lbr has been classified as Red List (Low Evidence).","entity_name":"LBR","entity_type":"gene"},{"created":"2019-12-06T12:58:10.986031+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.582","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LBR were changed from  to Greenberg skeletal dysplasia, MIM#215140; 3 Pelger-Huet anomaly, MIM#169400","entity_name":"LBR","entity_type":"gene"},{"created":"2019-12-06T12:57:53.010662+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.581","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LBR was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"LBR","entity_type":"gene"},{"created":"2019-12-06T12:57:45.660098+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.580","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: LBR as Red List (low evidence)","entity_name":"LBR","entity_type":"gene"},{"created":"2019-12-06T12:57:45.651782+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.580","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lbr has been classified as Red List (Low Evidence).","entity_name":"LBR","entity_type":"gene"},{"created":"2019-12-06T12:57:28.858430+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.579","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: LBR: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Greenberg skeletal dysplasia, MIM#215140, 3 Pelger-Huet anomaly, MIM#169400; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"LBR","entity_type":"gene"},{"created":"2019-12-06T12:43:33.839887+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.579","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: KYNU: Changed phenotypes: Hydroxykynureninuria, MIM#236800, Vertebral, cardiac, renal, and limb defects syndrome 2, MIM#617661","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-12-06T12:41:53.884184+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.579","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KYNU as ready","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-12-06T12:41:53.876955+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.579","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kynu has been classified as Red List (Low Evidence).","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-12-06T12:41:36.556422+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.579","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KYNU were changed from  to Hydroxykynureninuria, MIM#236800","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-12-06T12:41:20.650284+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.578","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KYNU were set to ","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-12-06T12:41:04.803130+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.577","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: KYNU as Red List (low evidence)","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-12-06T12:41:04.795444+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.577","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kynu has been classified as Red List (Low Evidence).","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-12-06T12:40:44.787913+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.576","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KYNU: Rating: RED; Mode of pathogenicity: None; Publications: 28792876, 17334708; Phenotypes: Hydroxykynureninuria, MIM#236800; Mode of inheritance: None","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-12-06T12:23:40.647104+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.576","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KMT5B as ready","entity_name":"KMT5B","entity_type":"gene"},{"created":"2019-12-06T12:23:40.639944+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.576","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kmt5b has been classified as Green List (High Evidence).","entity_name":"KMT5B","entity_type":"gene"},{"created":"2019-12-06T12:23:33.950340+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.576","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: KMT5B as Green List (high evidence)","entity_name":"KMT5B","entity_type":"gene"},{"created":"2019-12-06T12:23:33.943594+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.576","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kmt5b has been classified as Green List (High Evidence).","entity_name":"KMT5B","entity_type":"gene"},{"created":"2019-12-06T12:23:15.854401+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.575","user_name":"Zornitza Stark","item_type":"entity","text":"gene: KMT5B was added\ngene: KMT5B was added to Intellectual disability, syndromic and non-syndromic_GHQ. Sources: Expert list\nMode of inheritance for gene: KMT5B was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: KMT5B were set to 25363768; 28191889; 29276005\nPhenotypes for gene: KMT5B were set to Mental retardation, autosomal dominant 51, MIM#617788\nReview for gene: KMT5B was set to GREEN\nAdded comment: Multiple affected individuals from unrelated families. \nSources: Expert list","entity_name":"KMT5B","entity_type":"gene"},{"created":"2019-12-06T12:09:10.334356+11:00","panel_name":"Cancer Predisposition_Paediatric_VCGS","panel_id":152,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CHEK2 as ready","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:09:10.327305+11:00","panel_name":"Cancer Predisposition_Paediatric_VCGS","panel_id":152,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: chek2 has been classified as Green List (High Evidence).","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:09:05.160288+11:00","panel_name":"Cancer Predisposition_Paediatric_VCGS","panel_id":152,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: CHEK2 as Green List (high evidence)","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:09:05.152735+11:00","panel_name":"Cancer Predisposition_Paediatric_VCGS","panel_id":152,"panel_version":"0.3","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: chek2 has been classified as Green List (High Evidence).","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:08:20.215366+11:00","panel_name":"Cancer Predisposition_Paediatric_VCGS","panel_id":152,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"gene: CHEK2 was added\ngene: CHEK2 was added to Cancer Predisposition_Paediatric_VCGS. Sources: Expert Review\nMode of inheritance for gene: CHEK2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: CHEK2 were set to 10617473\nPhenotypes for gene: CHEK2 were set to Li-Fraumeni syndrome, MIM#609265\nReview for gene: CHEK2 was set to GREEN\nAdded comment: Affected individuals from three unrelated families reported originally. \nSources: Expert Review","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:04:12.286111+11:00","panel_name":"Incidentalome_VCGS","panel_id":126,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CHEK2 as ready","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:04:12.282898+11:00","panel_name":"Incidentalome_VCGS","panel_id":126,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Added comment: Comment when marking as ready: Decision to add to Incidentalome by Genomics MDT 6/12/19.","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:04:12.264476+11:00","panel_name":"Incidentalome_VCGS","panel_id":126,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: chek2 has been classified as Green List (High Evidence).","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:03:41.828525+11:00","panel_name":"Incidentalome_VCGS","panel_id":126,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: CHEK2 as Green List (high evidence)","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:03:41.815093+11:00","panel_name":"Incidentalome_VCGS","panel_id":126,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: chek2 has been classified as Green List (High Evidence).","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T12:03:11.202841+11:00","panel_name":"Incidentalome_VCGS","panel_id":126,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"entity","text":"gene: CHEK2 was added\ngene: CHEK2 was added to Incidentalome_VCGS. Sources: Other\nMode of inheritance for gene: CHEK2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: CHEK2 were set to Breast cancer\nReview for gene: CHEK2 was set to GREEN\nAdded comment: Sources: Other","entity_name":"CHEK2","entity_type":"gene"},{"created":"2019-12-06T10:55:50.917709+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.574","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KMT2B as ready","entity_name":"KMT2B","entity_type":"gene"},{"created":"2019-12-06T10:55:50.910172+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.574","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kmt2b has been classified as Green List (High Evidence).","entity_name":"KMT2B","entity_type":"gene"},{"created":"2019-12-06T10:55:44.305687+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.574","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KMT2B were changed from  to Dystonia 28, childhood-onset, MIM#617284","entity_name":"KMT2B","entity_type":"gene"},{"created":"2019-12-06T10:55:29.769912+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.573","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KMT2B was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KMT2B","entity_type":"gene"},{"created":"2019-12-06T10:55:15.598065+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.572","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KMT2B: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Dystonia 28, childhood-onset, MIM#617284; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KMT2B","entity_type":"gene"},{"created":"2019-12-06T10:53:19.244607+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.572","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KLLN were set to ","entity_name":"KLLN","entity_type":"gene"},{"created":"2019-12-06T10:53:06.711150+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.571","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: KLLN as Red List (low evidence)","entity_name":"KLLN","entity_type":"gene"},{"created":"2019-12-06T10:53:06.702898+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.571","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: klln has been classified as Red List (Low Evidence).","entity_name":"KLLN","entity_type":"gene"},{"created":"2019-12-06T10:52:54.517838+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.570","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KLLN: Rating: RED; Mode of pathogenicity: None; Publications: 21177507; Phenotypes: ; Mode of inheritance: None","entity_name":"KLLN","entity_type":"gene"},{"created":"2019-12-06T10:48:59.923645+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.570","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KLF8 as ready","entity_name":"KLF8","entity_type":"gene"},{"created":"2019-12-06T10:48:59.915158+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.570","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: klf8 has been classified as Red List (Low Evidence).","entity_name":"KLF8","entity_type":"gene"},{"created":"2019-12-06T10:48:52.505082+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.570","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KLF8 were set to ","entity_name":"KLF8","entity_type":"gene"},{"created":"2019-12-06T10:48:42.931472+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.569","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: KLF8 as Red List (low evidence)","entity_name":"KLF8","entity_type":"gene"},{"created":"2019-12-06T10:48:42.920593+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.569","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: klf8 has been classified as Red List (Low Evidence).","entity_name":"KLF8","entity_type":"gene"},{"created":"2019-12-06T10:47:45.297114+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.568","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KLF8: Rating: RED; Mode of pathogenicity: None; Publications: 11836360; Phenotypes: ; Mode of inheritance: None","entity_name":"KLF8","entity_type":"gene"},{"created":"2019-12-06T10:10:11.828981+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.166","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KLF7 as ready","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T10:10:11.820756+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.166","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: klf7 has been classified as Green List (High Evidence).","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T10:10:03.195588+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.166","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: KLF7 as Green List (high evidence)","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T10:10:03.187504+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.166","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: klf7 has been classified as Green List (High Evidence).","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T10:09:44.921232+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.165","user_name":"Zornitza Stark","item_type":"entity","text":"gene: KLF7 was added\ngene: KLF7 was added to Mendeliome_VCGS. Sources: Literature\nMode of inheritance for gene: KLF7 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: KLF7 were set to 29251763\nPhenotypes for gene: KLF7 were set to Intellectual disability\nReview for gene: KLF7 was set to GREEN\nAdded comment: Four unrelated individuals with de novo missense variants; animal model data supportive. \nSources: Literature","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T09:30:51.238566+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.568","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: KLF7 were changed from  to Intellectual disability","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T09:30:42.764881+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.567","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: KLF7 were set to ","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T09:30:28.189320+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.566","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: KLF7 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T09:30:09.727504+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.565","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: KLF7: Rating: GREEN; Mode of pathogenicity: None; Publications: 29251763; Phenotypes: Intellectual disability; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"KLF7","entity_type":"gene"},{"created":"2019-12-06T09:18:36.151916+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.565","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KIRREL3 as ready","entity_name":"KIRREL3","entity_type":"gene"},{"created":"2019-12-06T09:18:36.144261+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.565","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kirrel3 has been classified as Red List (Low Evidence).","entity_name":"KIRREL3","entity_type":"gene"}]}