{"count":220363,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2071","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2069","results":[{"created":"2019-12-05T12:42:43.766645+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.445","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mrps16 has been classified as Red List (Low Evidence).","entity_name":"MRPS16","entity_type":"gene"},{"created":"2019-12-05T12:42:43.515647+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.445","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MRPS16 as Red List (low evidence)","entity_name":"MRPS16","entity_type":"gene"},{"created":"2019-12-05T12:42:43.506804+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.445","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mrps16 has been classified as Red List (Low Evidence).","entity_name":"MRPS16","entity_type":"gene"},{"created":"2019-12-05T12:42:04.271653+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.444","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MRPS16.\nSource Expert list was added to MRPS16.\nMode of inheritance for gene MRPS16 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MRPS16 were changed from  to Combined oxidative phosphorylation deficiency 2; OMIM #610498\nPublications for gene MRPS16 were changed from PubMed: 15505824 to PubMed: 15505824","entity_name":"MRPS16","entity_type":"gene"},{"created":"2019-12-05T12:40:45.359558+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.443","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MRPS16: Rating: RED; Mode of pathogenicity: None; Publications: PubMed: 15505824; Phenotypes: Combined oxidative phosphorylation deficiency 2, OMIM #610498; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MRPS16","entity_type":"gene"},{"created":"2019-12-05T12:37:41.850670+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.443","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MRPL3 as Amber List (moderate evidence)","entity_name":"MRPL3","entity_type":"gene"},{"created":"2019-12-05T12:37:41.841334+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.443","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mrpl3 has been classified as Amber List (Moderate Evidence).","entity_name":"MRPL3","entity_type":"gene"},{"created":"2019-12-05T12:35:48.922972+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.442","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MRPL3.\nSource Expert list was added to MRPL3.\nMode of inheritance for gene MRPL3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MRPL3 were changed from  to Combined oxidative phosphorylation deficiency 9; OMIM #614582\nPublications for gene MRPL3 were changed from PubMed: 27815843; 21786366 to PubMed: 27815843; 21786366","entity_name":"MRPL3","entity_type":"gene"},{"created":"2019-12-05T12:35:08.416359+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.441","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MRPL3: Rating: AMBER; Mode of pathogenicity: None; Publications: PubMed: 27815843, 21786366; Phenotypes: Combined oxidative phosphorylation deficiency 9, OMIM #614582; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MRPL3","entity_type":"gene"},{"created":"2019-12-05T12:31:53.323318+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.441","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MRAP as Red List (low evidence)","entity_name":"MRAP","entity_type":"gene"},{"created":"2019-12-05T12:31:53.314423+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.441","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mrap has been classified as Red List (Low Evidence).","entity_name":"MRAP","entity_type":"gene"},{"created":"2019-12-05T12:31:37.490917+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.440","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MRAP.\nSource Expert list was added to MRAP.\nMode of inheritance for gene MRAP was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MRAP were changed from  to Glucocorticoid deficiency 2; OMIM #607398","entity_name":"MRAP","entity_type":"gene"},{"created":"2019-12-05T12:30:42.961465+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.439","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MRAP: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Glucocorticoid deficiency 2, OMIM #607398; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MRAP","entity_type":"gene"},{"created":"2019-12-05T12:28:38.188876+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.439","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MPV17.\nSource Expert list was added to MPV17.\nMode of inheritance for gene MPV17 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MPV17 were changed from  to Charcot-Marie-Tooth disease, axonal, type 2EE, OMIM #618400; Mitochondrial DNA depletion syndrome 6 (hepatocerebral type), OMIM #256810\nPublications for gene MPV17 were changed from PMID: 22593919 to PMID: 22593919","entity_name":"MPV17","entity_type":"gene"},{"created":"2019-12-05T12:27:47.946300+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.438","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MPV17: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22593919; Phenotypes: Charcot-Marie-Tooth disease, axonal, type 2EE, OMIM #618400, Mitochondrial DNA depletion syndrome 6 (hepatocerebral type), OMIM #256810; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MPV17","entity_type":"gene"},{"created":"2019-12-05T12:27:11.943354+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.438","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: IBA57 as ready","entity_name":"IBA57","entity_type":"gene"},{"created":"2019-12-05T12:27:11.935914+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.438","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: iba57 has been classified as Green List (High Evidence).","entity_name":"IBA57","entity_type":"gene"},{"created":"2019-12-05T12:27:07.933342+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.438","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: IBA57 were changed from  to Multiple mitochondrial dysfunctions syndrome 3, MIM#615330","entity_name":"IBA57","entity_type":"gene"},{"created":"2019-12-05T12:26:50.224746+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.437","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: IBA57 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"IBA57","entity_type":"gene"},{"created":"2019-12-05T12:26:33.661388+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.436","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: IBA57: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Multiple mitochondrial dysfunctions syndrome 3, MIM#615330; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"IBA57","entity_type":"gene"},{"created":"2019-12-05T12:23:13.090962+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.436","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MPZ as Red List (low evidence)","entity_name":"MPZ","entity_type":"gene"},{"created":"2019-12-05T12:23:13.083425+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.436","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mpz has been classified as Red List (Low Evidence).","entity_name":"MPZ","entity_type":"gene"},{"created":"2019-12-05T12:23:02.313974+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.435","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MPZ.\nSource Expert list was added to MPZ.\nMode of inheritance for gene MPZ was changed from Unknown to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal\nPhenotypes for gene: MPZ were changed from  to Various CMT types","entity_name":"MPZ","entity_type":"gene"},{"created":"2019-12-05T12:22:11.882499+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.434","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MPZ: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Various CMT types; Mode of inheritance: BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal","entity_name":"MPZ","entity_type":"gene"},{"created":"2019-12-05T12:20:24.708898+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.434","user_name":"Chirag Patel","item_type":"entity","text":"Publications for gene MPDZ were changed from PubMed: 28556411; 23240096 to PubMed: 28556411; 23240096","entity_name":"MPDZ","entity_type":"gene"},{"created":"2019-12-05T12:19:59.074904+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.433","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MPDZ.\nSource Expert list was added to MPDZ.\nMode of inheritance for gene MPDZ was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MPDZ were changed from  to Hydrocephalus, congenital, 2, with or without brain or eye anomalies; OMIM #615219","entity_name":"MPDZ","entity_type":"gene"},{"created":"2019-12-05T12:19:23.800157+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.432","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MPDZ: Rating: GREEN; Mode of pathogenicity: None; Publications: PubMed: 28556411, 23240096; Phenotypes: Hydrocephalus, congenital, 2, with or without brain or eye anomalies, OMIM #615219; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MPDZ","entity_type":"gene"},{"created":"2019-12-05T12:13:12.666291+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.432","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MNX1 as Red List (low evidence)","entity_name":"MNX1","entity_type":"gene"},{"created":"2019-12-05T12:13:12.659213+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.432","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mnx1 has been classified as Red List (Low Evidence).","entity_name":"MNX1","entity_type":"gene"},{"created":"2019-12-05T12:13:02.097121+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.431","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MNX1.\nSource Expert list was added to MNX1.\nMode of inheritance for gene MNX1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: MNX1 were changed from  to Currarino syndrome; OMIM #176450","entity_name":"MNX1","entity_type":"gene"},{"created":"2019-12-05T12:12:46.388648+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.430","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MNX1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Currarino syndrome, OMIM #176450; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"MNX1","entity_type":"gene"},{"created":"2019-12-05T12:11:35.770911+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.430","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MLH1 as Red List (low evidence)","entity_name":"MLH1","entity_type":"gene"},{"created":"2019-12-05T12:11:35.762369+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.430","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mlh1 has been classified as Red List (Low Evidence).","entity_name":"MLH1","entity_type":"gene"},{"created":"2019-12-05T12:11:24.584236+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.429","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MLH1.\nSource Expert list was added to MLH1.\nMode of inheritance for gene MLH1 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal\nPhenotypes for gene: MLH1 were changed from  to Mismatch repair cancer syndrome, OMIM #276300; Muir-Torre syndrome, OMIM #158320","entity_name":"MLH1","entity_type":"gene"},{"created":"2019-12-05T12:11:05.985368+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.428","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MLH1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Mismatch repair cancer syndrome, OMIM #276300, Muir-Torre syndrome, OMIM #158320; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"MLH1","entity_type":"gene"},{"created":"2019-12-05T12:09:51.458212+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.428","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MIR17HG.\nSource Expert list was added to MIR17HG.\nMode of inheritance for gene MIR17HG was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: MIR17HG were changed from  to Feingold syndrome 2; OMIM #614326\nPublications for gene MIR17HG were changed from PMID: 25391829; 21892160 to PMID: 25391829; 21892160","entity_name":"MIR17HG","entity_type":"gene"},{"created":"2019-12-05T12:09:24.174894+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.427","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MIR17HG: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 25391829, 21892160; Phenotypes: Feingold syndrome 2, OMIM #614326; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"MIR17HG","entity_type":"gene"},{"created":"2019-12-05T12:05:58.910876+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.427","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MID2 as Red List (low evidence)","entity_name":"MID2","entity_type":"gene"},{"created":"2019-12-05T12:05:58.902024+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.427","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mid2 has been classified as Red List (Low Evidence).","entity_name":"MID2","entity_type":"gene"},{"created":"2019-12-05T12:05:47.881526+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.426","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MID2.\nSource Expert list was added to MID2.\nMode of inheritance for gene MID2 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females\nPhenotypes for gene: MID2 were changed from  to ?Mental retardation, X-linked 101; OMIM#300928\nPublications for gene MID2 were changed from PubMed: 24115387 to PubMed: 24115387","entity_name":"MID2","entity_type":"gene"},{"created":"2019-12-05T12:05:21.693302+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.425","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MID2: Rating: RED; Mode of pathogenicity: None; Publications: PubMed: 24115387; Phenotypes: ?Mental retardation, X-linked 101, OMIM#300928; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"MID2","entity_type":"gene"},{"created":"2019-12-05T12:03:06.144692+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.425","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MGP as Red List (low evidence)","entity_name":"MGP","entity_type":"gene"},{"created":"2019-12-05T12:03:06.136949+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.425","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mgp has been classified as Red List (Low Evidence).","entity_name":"MGP","entity_type":"gene"},{"created":"2019-12-05T12:02:54.161362+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.424","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MGP.\nSource Expert list was added to MGP.\nMode of inheritance for gene MGP was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MGP were changed from  to Keutel syndrome; OMIM #245150","entity_name":"MGP","entity_type":"gene"},{"created":"2019-12-05T12:02:12.120053+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.423","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MGP: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Keutel syndrome, OMIM #245150; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MGP","entity_type":"gene"},{"created":"2019-12-05T12:01:21.999667+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.423","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MGME1 as Red List (low evidence)","entity_name":"MGME1","entity_type":"gene"},{"created":"2019-12-05T12:01:21.991413+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.423","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mgme1 has been classified as Red List (Low Evidence).","entity_name":"MGME1","entity_type":"gene"},{"created":"2019-12-05T12:01:12.589651+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.422","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MGME1.\nSource Expert list was added to MGME1.\nMode of inheritance for gene MGME1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MGME1 were changed from  to Mitochondrial DNA depletion syndrome 11; OMIM#615084\nPublications for gene MGME1 were changed from PubMed: 23313956 to PubMed: 23313956","entity_name":"MGME1","entity_type":"gene"},{"created":"2019-12-05T12:00:34.757940+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.421","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MGME1: Rating: RED; Mode of pathogenicity: None; Publications: PubMed: 23313956; Phenotypes: Mitochondrial DNA depletion syndrome 11, OMIM#615084; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MGME1","entity_type":"gene"},{"created":"2019-12-05T11:57:49.477230+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.421","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MFN2 as Red List (low evidence)","entity_name":"MFN2","entity_type":"gene"},{"created":"2019-12-05T11:57:49.464844+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.421","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mfn2 has been classified as Red List (Low Evidence).","entity_name":"MFN2","entity_type":"gene"},{"created":"2019-12-05T11:57:35.749350+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.420","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MFN2.\nSource Expert list was added to MFN2.\nMode of inheritance for gene MFN2 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal\nPhenotypes for gene: MFN2 were changed from  to Charcot-Marie-Tooth disease, axonal, type 2A2A, OMIM #609260; Charcot-Marie-Tooth disease, axonal, type 2A2B, OMIM #617087; Hereditary motor and sensory neuropathy VIA, OMIM #601152","entity_name":"MFN2","entity_type":"gene"},{"created":"2019-12-05T11:57:20.552723+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.419","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MFN2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Charcot-Marie-Tooth disease, axonal, type 2A2A, OMIM #609260, Charcot-Marie-Tooth disease, axonal, type 2A2B, OMIM #617087, Hereditary motor and sensory neuropathy VIA, OMIM #601152; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"MFN2","entity_type":"gene"},{"created":"2019-12-05T11:55:23.404868+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.419","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from METTL23.\nSource Expert list was added to METTL23.\nMode of inheritance for gene METTL23 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: METTL23 were changed from  to Mental retardation, autosomal recessive 44; OMIM#615942\nPublications for gene METTL23 were changed from PubMed: 24501276; 24626631 to PubMed: 24501276; 24626631","entity_name":"METTL23","entity_type":"gene"},{"created":"2019-12-05T11:54:49.229435+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.418","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: METTL23: Rating: GREEN; Mode of pathogenicity: None; Publications: PubMed: 24501276, 24626631; Phenotypes: Mental retardation, autosomal recessive 44, OMIM#615942; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"METTL23","entity_type":"gene"},{"created":"2019-12-05T11:51:03.102599+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.418","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MET as Red List (low evidence)","entity_name":"MET","entity_type":"gene"},{"created":"2019-12-05T11:51:03.094299+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.418","user_name":"Chirag Patel","item_type":"entity","text":"Gene: met has been classified as Red List (Low Evidence).","entity_name":"MET","entity_type":"gene"},{"created":"2019-12-05T11:50:47.844900+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.417","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MET.\nSource Expert list was added to MET.\nMode of inheritance for gene MET was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal\nPhenotypes for gene: MET were changed from  to ?Deafness, autosomal recessive 97, OMIM #616705; {Osteofibrous dysplasia, susceptibility to}, OMIM #607278","entity_name":"MET","entity_type":"gene"},{"created":"2019-12-05T11:50:33.327669+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.416","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MET: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ?Deafness, autosomal recessive 97, OMIM #616705, {Osteofibrous dysplasia, susceptibility to}, OMIM #607278; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"MET","entity_type":"gene"},{"created":"2019-12-05T11:49:17.790203+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.416","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MEGF8.\nSource Expert list was added to MEGF8.\nMode of inheritance for gene MEGF8 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MEGF8 were changed from  to Carpenter syndrome 2; OMIM #614976","entity_name":"MEGF8","entity_type":"gene"},{"created":"2019-12-05T11:48:27.916872+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.415","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MEGF8: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 3993675; Phenotypes: Carpenter syndrome 2, OMIM #614976; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MEGF8","entity_type":"gene"},{"created":"2019-12-05T11:44:08.357649+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.415","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MCM4 as Red List (low evidence)","entity_name":"MCM4","entity_type":"gene"},{"created":"2019-12-05T11:44:08.350384+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.415","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mcm4 has been classified as Red List (Low Evidence).","entity_name":"MCM4","entity_type":"gene"},{"created":"2019-12-05T11:43:59.171762+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.414","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MCM4.\nSource Expert list was added to MCM4.\nMode of inheritance for gene MCM4 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MCM4 were changed from  to Immunodeficiency 54; OMIM #609981","entity_name":"MCM4","entity_type":"gene"},{"created":"2019-12-05T11:43:39.137986+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.413","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MCM4: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Immunodeficiency 54, OMIM #609981; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MCM4","entity_type":"gene"},{"created":"2019-12-05T11:42:05.920329+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.413","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MARS2 as Amber List (moderate evidence)","entity_name":"MARS2","entity_type":"gene"},{"created":"2019-12-05T11:42:05.911479+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.413","user_name":"Chirag Patel","item_type":"entity","text":"Gene: mars2 has been classified as Amber List (Moderate Evidence).","entity_name":"MARS2","entity_type":"gene"},{"created":"2019-12-05T11:41:55.478380+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.412","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MARS2.\nSource Expert list was added to MARS2.\nMode of inheritance for gene MARS2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: MARS2 were changed from  to ?Combined oxidative phosphorylation deficiency 25, OMIM #616430; Spastic ataxia 3, autosomal recessive, OMIM #611390\nPublications for gene MARS2 were changed from PMID: 25754315 to PMID: 25754315","entity_name":"MARS2","entity_type":"gene"},{"created":"2019-12-05T11:41:23.280379+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.411","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MARS2: Rating: AMBER; Mode of pathogenicity: None; Publications: PubMed: 25754315; Phenotypes: ?Combined oxidative phosphorylation deficiency 25, OMIM #616430, Spastic ataxia 3, autosomal recessive, OMIM #611390; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"MARS2","entity_type":"gene"},{"created":"2019-12-05T10:58:27.604897+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.411","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: HYLS1 as ready","entity_name":"HYLS1","entity_type":"gene"},{"created":"2019-12-05T10:58:27.597618+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.411","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: hyls1 has been classified as Red List (Low Evidence).","entity_name":"HYLS1","entity_type":"gene"},{"created":"2019-12-05T10:58:21.999346+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.411","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: HYLS1 were changed from  to Hydrolethalus syndrome, MIM#236680","entity_name":"HYLS1","entity_type":"gene"},{"created":"2019-12-05T10:58:10.627021+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.410","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: HYLS1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"HYLS1","entity_type":"gene"},{"created":"2019-12-05T10:57:59.555163+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.409","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: HYLS1 as Red List (low evidence)","entity_name":"HYLS1","entity_type":"gene"},{"created":"2019-12-05T10:57:59.547670+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.409","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: hyls1 has been classified as Red List (Low Evidence).","entity_name":"HYLS1","entity_type":"gene"},{"created":"2019-12-05T10:57:46.807901+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.408","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: HYLS1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Hydrolethalus syndrome, MIM#236680; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"HYLS1","entity_type":"gene"},{"created":"2019-12-05T10:52:34.524936+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.408","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: HSPG2 as ready","entity_name":"HSPG2","entity_type":"gene"},{"created":"2019-12-05T10:52:34.513383+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.408","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: hspg2 has been classified as Green List (High Evidence).","entity_name":"HSPG2","entity_type":"gene"},{"created":"2019-12-05T10:52:29.860300+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.408","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: HSPG2 were changed from  to Schwartz-Jampel syndrome, type 1, MIM#255800","entity_name":"HSPG2","entity_type":"gene"},{"created":"2019-12-05T10:52:14.583715+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.407","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: HSPG2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"HSPG2","entity_type":"gene"},{"created":"2019-12-05T10:52:01.548273+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.406","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: HSPG2: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Schwartz-Jampel syndrome, type 1, MIM#255800; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"HSPG2","entity_type":"gene"},{"created":"2019-12-05T10:51:17.055773+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.406","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: MAGT1 as Amber List (moderate evidence)","entity_name":"MAGT1","entity_type":"gene"},{"created":"2019-12-05T10:51:17.048745+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.406","user_name":"Chirag Patel","item_type":"entity","text":"Gene: magt1 has been classified as Amber List (Moderate Evidence).","entity_name":"MAGT1","entity_type":"gene"},{"created":"2019-12-05T10:51:07.357526+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.405","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from MAGT1.\nSource Expert list was added to MAGT1.\nMode of inheritance for gene MAGT1 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females\nPhenotypes for gene: MAGT1 were changed from  to Congenital disorder of glycosylation, type Icc, OMIM #301031; Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia, OMIM #300853\nPublications for gene MAGT1 were changed from PMID: 31036665 to PMID: 31036665","entity_name":"MAGT1","entity_type":"gene"},{"created":"2019-12-05T10:50:42.993439+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.404","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: MAGT1: Rating: AMBER; Mode of pathogenicity: None; Publications: PubMed: 31036665; Phenotypes: Congenital disorder of glycosylation, type Icc, OMIM #301031, Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia, OMIM #300853; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"MAGT1","entity_type":"gene"},{"created":"2019-12-05T10:48:39.375250+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.404","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: HOXD10 as ready","entity_name":"HOXD10","entity_type":"gene"},{"created":"2019-12-05T10:48:39.367931+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.404","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: hoxd10 has been classified as Red List (Low Evidence).","entity_name":"HOXD10","entity_type":"gene"},{"created":"2019-12-05T10:48:35.298168+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.404","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: HOXD10 were changed from  to Vertical talus, congenital, MIM#192950","entity_name":"HOXD10","entity_type":"gene"},{"created":"2019-12-05T10:48:19.998478+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.403","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: HOXD10 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"HOXD10","entity_type":"gene"},{"created":"2019-12-05T10:48:09.222543+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.402","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: HOXD10 as Red List (low evidence)","entity_name":"HOXD10","entity_type":"gene"},{"created":"2019-12-05T10:48:09.214967+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.402","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: hoxd10 has been classified as Red List (Low Evidence).","entity_name":"HOXD10","entity_type":"gene"},{"created":"2019-12-05T10:47:56.235892+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.401","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: HOXD10: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Vertical talus, congenital, MIM#192950; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"HOXD10","entity_type":"gene"},{"created":"2019-12-05T10:45:46.807691+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.401","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: ORC4 as Red List (low evidence)","entity_name":"ORC4","entity_type":"gene"},{"created":"2019-12-05T10:45:46.798468+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.401","user_name":"Chirag Patel","item_type":"entity","text":"Gene: orc4 has been classified as Red List (Low Evidence).","entity_name":"ORC4","entity_type":"gene"},{"created":"2019-12-05T10:45:33.890909+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.400","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from ORC4.\nSource Expert list was added to ORC4.\nMode of inheritance for gene ORC4 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: ORC4 were changed from  to Meier-Gorlin syndrome 2; OMIM #613800","entity_name":"ORC4","entity_type":"gene"},{"created":"2019-12-05T10:45:15.373878+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.399","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: ORC4: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Meier-Gorlin syndrome 2, OMIM #613800; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ORC4","entity_type":"gene"},{"created":"2019-12-05T10:44:21.593698+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.399","user_name":"Chirag Patel","item_type":"entity","text":"Classified gene: ORC6 as Red List (low evidence)","entity_name":"ORC6","entity_type":"gene"},{"created":"2019-12-05T10:44:21.585180+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.399","user_name":"Chirag Patel","item_type":"entity","text":"Gene: orc6 has been classified as Red List (Low Evidence).","entity_name":"ORC6","entity_type":"gene"},{"created":"2019-12-05T10:44:11.575006+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.398","user_name":"Chirag Patel","item_type":"entity","text":"Source Genetic Health Queensland was removed from ORC6.\nSource Expert list was added to ORC6.\nMode of inheritance for gene ORC6 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: ORC6 were changed from  to Meier-Gorlin syndrome 3; OMIM #613803","entity_name":"ORC6","entity_type":"gene"},{"created":"2019-12-05T10:43:57.121401+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.397","user_name":"Chirag Patel","item_type":"entity","text":"reviewed gene: ORC6: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Meier-Gorlin syndrome 3, OMIM #613803; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"ORC6","entity_type":"gene"}]}