{"count":220324,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2082","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=2080","results":[{"created":"2019-11-29T13:38:23.158402+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.108","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: COX14 were set to ","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:38:09.158809+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.107","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: COX14 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:38:01.028560+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.106","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: COX14 as Amber List (moderate evidence)","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:38:01.018703+11:00","panel_name":"Mendeliome_VCGS","panel_id":137,"panel_version":"0.106","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cox14 has been classified as Amber List (Moderate Evidence).","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:29:27.923946+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COX14 as ready","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:29:27.916833+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cox14 has been classified as Amber List (Moderate Evidence).","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:29:23.597259+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: COX14 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:28:46.238925+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.13","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: COX14 were changed from  to Mitochondrial complex IV deficiency, MIM#220110","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:28:13.597373+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: COX14 were set to ","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:27:46.972157+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: COX14 as Amber List (moderate evidence)","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:27:46.964744+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cox14 has been classified as Amber List (Moderate Evidence).","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:27:19.789328+11:00","panel_name":"Regression_VCGS","panel_id":206,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COX14: Rating: AMBER; Mode of pathogenicity: None; Publications: 22243966; Phenotypes: Mitochondrial complex IV deficiency, MIM#220110; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:22:31.670520+11:00","panel_name":"Mitochondrial_AustralianGenomics_VCGS","panel_id":203,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COX14 as ready","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:22:31.662363+11:00","panel_name":"Mitochondrial_AustralianGenomics_VCGS","panel_id":203,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cox14 has been classified as Amber List (Moderate Evidence).","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:19:15.796361+11:00","panel_name":"Mitochondrial_AustralianGenomics_VCGS","panel_id":203,"panel_version":"0.11","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: COX14 were changed from  to Mitochondrial complex IV deficiency, MIM#220110","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:18:56.121403+11:00","panel_name":"Mitochondrial_AustralianGenomics_VCGS","panel_id":203,"panel_version":"0.10","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: COX14 were set to ","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:18:31.640974+11:00","panel_name":"Mitochondrial_AustralianGenomics_VCGS","panel_id":203,"panel_version":"0.9","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: COX14 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:18:04.918332+11:00","panel_name":"Mitochondrial_AustralianGenomics_VCGS","panel_id":203,"panel_version":"0.8","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: COX14 as Amber List (moderate evidence)","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:18:04.903256+11:00","panel_name":"Mitochondrial_AustralianGenomics_VCGS","panel_id":203,"panel_version":"0.8","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cox14 has been classified as Amber List (Moderate Evidence).","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:17:38.104549+11:00","panel_name":"Mitochondrial_AustralianGenomics_VCGS","panel_id":203,"panel_version":"0.7","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COX14: Rating: AMBER; Mode of pathogenicity: None; Publications: 22243966; Phenotypes: Mitochondrial complex IV deficiency, MIM#220110; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:15:56.590682+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.37","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COX14 as ready","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:15:56.582350+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.37","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cox14 has been classified as Amber List (Moderate Evidence).","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:15:52.335364+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.37","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: COX14 were changed from  to Mitochondrial complex IV deficiency, MIM#220110","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:15:37.061307+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.36","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: COX14 were set to ","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:15:22.273100+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.35","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: COX14 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:15:10.782153+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.34","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: COX14 as Amber List (moderate evidence)","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:15:10.773763+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.34","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cox14 has been classified as Amber List (Moderate Evidence).","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T13:14:58.165135+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.33","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COX14: Rating: AMBER; Mode of pathogenicity: None; Publications: 22243966; Phenotypes: Mitochondrial complex IV deficiency, MIM#220110; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COX14","entity_type":"gene"},{"created":"2019-11-29T10:41:35.111878+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.33","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CORO1A as ready","entity_name":"CORO1A","entity_type":"gene"},{"created":"2019-11-29T10:41:35.104335+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.33","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: coro1a has been classified as Red List (Low Evidence).","entity_name":"CORO1A","entity_type":"gene"},{"created":"2019-11-29T10:41:31.027998+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.33","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CORO1A were changed from  to Immunodeficiency 8, MIM#615401","entity_name":"CORO1A","entity_type":"gene"},{"created":"2019-11-29T10:41:12.680896+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.32","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CORO1A was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"CORO1A","entity_type":"gene"},{"created":"2019-11-29T10:40:59.803211+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.31","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: CORO1A as Red List (low evidence)","entity_name":"CORO1A","entity_type":"gene"},{"created":"2019-11-29T10:40:59.795234+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.31","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: coro1a has been classified as Red List (Low Evidence).","entity_name":"CORO1A","entity_type":"gene"},{"created":"2019-11-29T10:40:16.159975+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.30","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CORO1A: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Immunodeficiency 8, MIM#615401; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"CORO1A","entity_type":"gene"},{"created":"2019-11-29T10:25:07.380010+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.30","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COQ9: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Coenzyme Q10 deficiency, primary, 5, MIM#614654; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COQ9","entity_type":"gene"},{"created":"2019-11-29T08:50:51.644089+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ATP7A as ready","entity_name":"ATP7A","entity_type":"gene"},{"created":"2019-11-29T08:50:51.636918+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: atp7a has been classified as Green List (High Evidence).","entity_name":"ATP7A","entity_type":"gene"},{"created":"2019-11-29T08:50:41.437199+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ATP7A as Green List (high evidence)","entity_name":"ATP7A","entity_type":"gene"},{"created":"2019-11-29T08:50:41.425451+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.2","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: atp7a has been classified as Green List (High Evidence).","entity_name":"ATP7A","entity_type":"gene"},{"created":"2019-11-29T08:50:13.399437+11:00","panel_name":"Aortopathy, Connective tissue disorder_VCGS","panel_id":44,"panel_version":"0.1","user_name":"Zornitza Stark","item_type":"entity","text":"gene: ATP7A was added\ngene: ATP7A was added to Aortopathy, Connective tissue disorder_VCGS. Sources: Expert list\nMode of inheritance for gene: ATP7A was set to X-LINKED: hemizygous mutation in males, biallelic mutations in females\nPhenotypes for gene: ATP7A were set to Occipital horn syndrome, MIM#304150; Menkes disease, MIM#309400\nReview for gene: ATP7A was set to GREEN\nAdded comment: Connective tissue laxity is a prominent part of the phenotype. \nSources: Expert list","entity_name":"ATP7A","entity_type":"gene"},{"created":"2019-11-29T07:37:06.117516+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.30","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COQ2 as ready","entity_name":"COQ2","entity_type":"gene"},{"created":"2019-11-29T07:37:06.109972+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.30","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: coq2 has been classified as Green List (High Evidence).","entity_name":"COQ2","entity_type":"gene"},{"created":"2019-11-29T07:37:01.429434+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.30","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: COQ2 were changed from  to Coenzyme Q10 deficiency, primary, 1, MIM#607426","entity_name":"COQ2","entity_type":"gene"},{"created":"2019-11-29T07:36:43.260005+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.29","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: COQ2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"COQ2","entity_type":"gene"},{"created":"2019-11-29T07:36:25.870447+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COQ2: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Coenzyme Q10 deficiency, primary, 1, MIM#607426; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COQ2","entity_type":"gene"},{"created":"2019-11-29T07:27:43.273385+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COL18A1 as ready","entity_name":"COL18A1","entity_type":"gene"},{"created":"2019-11-29T07:27:43.264590+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: col18a1 has been classified as Red List (Low Evidence).","entity_name":"COL18A1","entity_type":"gene"},{"created":"2019-11-29T07:27:38.546013+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.28","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: COL18A1 were changed from  to Knobloch syndrome, type 1, MIM#267750","entity_name":"COL18A1","entity_type":"gene"},{"created":"2019-11-29T07:27:21.422164+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.27","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: COL18A1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"COL18A1","entity_type":"gene"},{"created":"2019-11-29T07:27:12.791315+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: COL18A1 as Red List (low evidence)","entity_name":"COL18A1","entity_type":"gene"},{"created":"2019-11-29T07:27:12.783310+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.26","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: col18a1 has been classified as Red List (Low Evidence).","entity_name":"COL18A1","entity_type":"gene"},{"created":"2019-11-29T07:26:58.230440+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COL18A1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Knobloch syndrome, type 1, MIM#267750; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COL18A1","entity_type":"gene"},{"created":"2019-11-29T06:33:28.518909+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COG6: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Congenital disorder of glycosylation, type Iil, MIM#614576; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COG6","entity_type":"gene"},{"created":"2019-11-29T06:31:52.330154+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CNTNAP5 as ready","entity_name":"CNTNAP5","entity_type":"gene"},{"created":"2019-11-29T06:31:52.322727+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cntnap5 has been classified as Red List (Low Evidence).","entity_name":"CNTNAP5","entity_type":"gene"},{"created":"2019-11-29T06:31:47.459255+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.25","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CNTNAP5 were changed from  to Autism","entity_name":"CNTNAP5","entity_type":"gene"},{"created":"2019-11-29T06:31:31.576984+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.24","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CNTNAP5 were set to ","entity_name":"CNTNAP5","entity_type":"gene"},{"created":"2019-11-29T06:31:14.953625+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.23","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CNTNAP5 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"CNTNAP5","entity_type":"gene"},{"created":"2019-11-29T06:30:48.127546+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.22","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: CNTNAP5 as Red List (low evidence)","entity_name":"CNTNAP5","entity_type":"gene"},{"created":"2019-11-29T06:30:48.119502+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.22","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cntnap5 has been classified as Red List (Low Evidence).","entity_name":"CNTNAP5","entity_type":"gene"},{"created":"2019-11-29T06:30:14.635695+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CNTNAP5: Rating: RED; Mode of pathogenicity: None; Publications: 20346443; Phenotypes: Autism; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"CNTNAP5","entity_type":"gene"},{"created":"2019-11-28T18:42:52.803484+11:00","panel_name":"Arthrogryposis_VCGS","panel_id":47,"panel_version":"0.7","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CNTNAP1 as ready","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:42:52.795582+11:00","panel_name":"Arthrogryposis_VCGS","panel_id":47,"panel_version":"0.7","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cntnap1 has been classified as Green List (High Evidence).","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:42:44.285399+11:00","panel_name":"Arthrogryposis_VCGS","panel_id":47,"panel_version":"0.7","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CNTNAP1 were changed from  to Hypomyelinating neuropathy, congenital, 3, MIM#618186; Lethal congenital contracture syndrome 7, MIM# 616286","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:41:58.987231+11:00","panel_name":"Arthrogryposis_VCGS","panel_id":47,"panel_version":"0.6","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CNTNAP1 were set to ","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:41:27.912874+11:00","panel_name":"Arthrogryposis_VCGS","panel_id":47,"panel_version":"0.5","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CNTNAP1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:35:43.576459+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CNTNAP1 as ready","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:35:43.564838+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cntnap1 has been classified as Green List (High Evidence).","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:27:54.612663+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CNTNAP1 were changed from  to Hypomyelinating neuropathy, congenital, 3, MIM#618186; Lethal congenital contracture syndrome 7, MIM# 616286","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:27:37.707046+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CNTNAP1 were set to ","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:27:25.462238+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: CNTNAP1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T18:27:10.149590+11:00","panel_name":"Intellectual disability, syndromic and non-syndromic_GHQ","panel_id":250,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: CNTNAP1: Rating: GREEN; Mode of pathogenicity: None; Publications: 28374019, 29511323, 27668699; Phenotypes: Hypomyelinating neuropathy, congenital, 3, MIM#618186, Lethal congenital contracture syndrome 7, MIM# 616286; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"CNTNAP1","entity_type":"gene"},{"created":"2019-11-28T17:16:47.903248+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.22","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ZIC3 as ready","entity_name":"ZIC3","entity_type":"gene"},{"created":"2019-11-28T17:16:47.895994+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.22","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zic3 has been classified as Green List (High Evidence).","entity_name":"ZIC3","entity_type":"gene"},{"created":"2019-11-28T17:16:43.024821+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.22","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ZIC3 as Green List (high evidence)","entity_name":"ZIC3","entity_type":"gene"},{"created":"2019-11-28T17:16:43.016761+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.22","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: zic3 has been classified as Green List (High Evidence).","entity_name":"ZIC3","entity_type":"gene"},{"created":"2019-11-28T17:16:15.531752+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.21","user_name":"Zornitza Stark","item_type":"entity","text":"gene: ZIC3 was added\ngene: ZIC3 was added to Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS. Sources: Expert list\nMode of inheritance for gene: ZIC3 was set to X-LINKED: hemizygous mutation in males, biallelic mutations in females\nPhenotypes for gene: ZIC3 were set to VACTERL association, X-linked, MIM#314390\nReview for gene: ZIC3 was set to GREEN\nAdded comment: Sources: Expert list","entity_name":"ZIC3","entity_type":"gene"},{"created":"2019-11-28T17:10:45.467433+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: WNT5A as ready","entity_name":"WNT5A","entity_type":"gene"},{"created":"2019-11-28T17:10:45.460059+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: wnt5a has been classified as Green List (High Evidence).","entity_name":"WNT5A","entity_type":"gene"},{"created":"2019-11-28T17:10:39.686782+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: WNT5A as Green List (high evidence)","entity_name":"WNT5A","entity_type":"gene"},{"created":"2019-11-28T17:10:39.679436+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.20","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: wnt5a has been classified as Green List (High Evidence).","entity_name":"WNT5A","entity_type":"gene"},{"created":"2019-11-28T17:10:11.378748+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.19","user_name":"Zornitza Stark","item_type":"entity","text":"gene: WNT5A was added\ngene: WNT5A was added to Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS. Sources: Expert list\nMode of inheritance for gene: WNT5A was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: WNT5A were set to Robinow syndrome, autosomal dominant 1, MIM#180700\nReview for gene: WNT5A was set to GREEN\nAdded comment: Renal anomalies in about a quarter. \nSources: Expert list","entity_name":"WNT5A","entity_type":"gene"},{"created":"2019-11-28T17:04:30.230862+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: STRA6 as ready","entity_name":"STRA6","entity_type":"gene"},{"created":"2019-11-28T17:04:30.222238+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: stra6 has been classified as Green List (High Evidence).","entity_name":"STRA6","entity_type":"gene"},{"created":"2019-11-28T17:04:25.625826+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: STRA6 as Green List (high evidence)","entity_name":"STRA6","entity_type":"gene"},{"created":"2019-11-28T17:04:25.614645+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.18","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: stra6 has been classified as Green List (High Evidence).","entity_name":"STRA6","entity_type":"gene"},{"created":"2019-11-28T17:03:57.214001+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.17","user_name":"Zornitza Stark","item_type":"entity","text":"gene: STRA6 was added\ngene: STRA6 was added to Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS. Sources: Expert list\nMode of inheritance for gene: STRA6 was set to BIALLELIC, autosomal or pseudoautosomal\nPhenotypes for gene: STRA6 were set to Microphthalmia, isolated, with coloboma 8, MIM#601186\nReview for gene: STRA6 was set to GREEN\nAdded comment: CAKUT is part of the phenotype \nSources: Expert list","entity_name":"STRA6","entity_type":"gene"},{"created":"2019-11-28T16:56:07.184882+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: KYNU as ready","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-11-28T16:56:07.177316+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kynu has been classified as Green List (High Evidence).","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-11-28T16:56:02.187557+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: KYNU as Green List (high evidence)","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-11-28T16:56:02.178918+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.16","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: kynu has been classified as Green List (High Evidence).","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-11-28T16:55:36.335418+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.15","user_name":"Zornitza Stark","item_type":"entity","text":"gene: KYNU was added\ngene: KYNU was added to Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS. Sources: Expert list\nMode of inheritance for gene: KYNU was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: KYNU were set to 28792876\nPhenotypes for gene: KYNU were set to Vertebral, cardiac, renal, and limb defects syndrome 2, MIM#617661\nReview for gene: KYNU was set to GREEN\nAdded comment: Two unrelated individuals plus functional data. \nSources: Expert list","entity_name":"KYNU","entity_type":"gene"},{"created":"2019-11-28T16:51:09.976543+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: HAAO as ready","entity_name":"HAAO","entity_type":"gene"},{"created":"2019-11-28T16:51:09.969312+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: haao has been classified as Green List (High Evidence).","entity_name":"HAAO","entity_type":"gene"},{"created":"2019-11-28T16:51:01.805518+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: HAAO as Green List (high evidence)","entity_name":"HAAO","entity_type":"gene"},{"created":"2019-11-28T16:51:01.797625+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.14","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: haao has been classified as Green List (High Evidence).","entity_name":"HAAO","entity_type":"gene"},{"created":"2019-11-28T16:50:24.820774+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.13","user_name":"Zornitza Stark","item_type":"entity","text":"gene: HAAO was added\ngene: HAAO was added to Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS. Sources: Expert list\nMode of inheritance for gene: HAAO was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: HAAO were set to 28792876\nPhenotypes for gene: HAAO were set to Vertebral, cardiac, renal, and limb defects syndrome 1, MIM#617660\nReview for gene: HAAO was set to GREEN\nAdded comment: Two unrelated individuals, functional data. \nSources: Expert list","entity_name":"HAAO","entity_type":"gene"},{"created":"2019-11-28T16:46:20.419160+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FGFR3 as ready","entity_name":"FGFR3","entity_type":"gene"},{"created":"2019-11-28T16:46:20.411591+11:00","panel_name":"Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic_VCGS","panel_id":63,"panel_version":"0.12","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fgfr3 has been classified as Green List (High Evidence).","entity_name":"FGFR3","entity_type":"gene"}]}