{"count":221415,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=357","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=355","results":[{"created":"2024-10-31T12:36:52.921072+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.535","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: ANKS6 as ready","entity_name":"ANKS6","entity_type":"gene"},{"created":"2024-10-31T12:36:52.910316+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.535","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: anks6 has been classified as Green List (High Evidence).","entity_name":"ANKS6","entity_type":"gene"},{"created":"2024-10-31T12:36:47.911949+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.535","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: ANKS6 were changed from Nephronophthisis 16, 615382 (3) to Nephronophthisis 16 MIM#615382","entity_name":"ANKS6","entity_type":"gene"},{"created":"2024-10-31T12:36:35.678987+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.534","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: ANKS6 were set to ","entity_name":"ANKS6","entity_type":"gene"},{"created":"2024-10-31T12:36:06.698901+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.533","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: BBS9 as ready","entity_name":"BBS9","entity_type":"gene"},{"created":"2024-10-31T12:36:06.683079+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.533","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: bbs9 has been classified as Green List (High Evidence).","entity_name":"BBS9","entity_type":"gene"},{"created":"2024-10-31T12:36:03.368047+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.533","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: BBS9 were changed from Bardet-Biedl syndrome 9, 615986 (3) to Bardet-Biedl syndrome 9 MIM#615986","entity_name":"BBS9","entity_type":"gene"},{"created":"2024-10-31T12:35:49.472700+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.532","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: BBS9 were set to ","entity_name":"BBS9","entity_type":"gene"},{"created":"2024-10-31T12:35:24.437103+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.531","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: BOLA3 as ready","entity_name":"BOLA3","entity_type":"gene"},{"created":"2024-10-31T12:35:24.400613+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.531","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: bola3 has been classified as Green List (High Evidence).","entity_name":"BOLA3","entity_type":"gene"},{"created":"2024-10-31T12:35:21.330346+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.531","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: BOLA3 were changed from Multiple mitochondrial dysfunctions syndrome 2, 614299 (3) to Multiple mitochondrial dysfunctions syndrome 2 with hyperglycinemia MIM#614299","entity_name":"BOLA3","entity_type":"gene"},{"created":"2024-10-31T12:35:10.959854+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.530","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: BOLA3 were set to ","entity_name":"BOLA3","entity_type":"gene"},{"created":"2024-10-31T12:34:43.539047+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.529","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CASR as ready","entity_name":"CASR","entity_type":"gene"},{"created":"2024-10-31T12:34:43.527453+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.529","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: casr has been classified as Green List (High Evidence).","entity_name":"CASR","entity_type":"gene"},{"created":"2024-10-31T12:34:40.274430+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.529","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CASR were changed from Hyperparathyroidism, neonatal, 239200 (3) to Hyperparathyroidism, neonatal MIM#239200","entity_name":"CASR","entity_type":"gene"},{"created":"2024-10-31T12:34:28.213477+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.528","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CASR were set to ","entity_name":"CASR","entity_type":"gene"},{"created":"2024-10-31T12:33:04.255533+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.527","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CCBE1 as ready","entity_name":"CCBE1","entity_type":"gene"},{"created":"2024-10-31T12:33:04.239829+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.527","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ccbe1 has been classified as Green List (High Evidence).","entity_name":"CCBE1","entity_type":"gene"},{"created":"2024-10-31T12:32:57.700898+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.527","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CCBE1 were set to ","entity_name":"CCBE1","entity_type":"gene"},{"created":"2024-10-31T12:32:18.320101+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.526","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CCDC39 as ready","entity_name":"CCDC39","entity_type":"gene"},{"created":"2024-10-31T12:32:18.305204+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.526","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ccdc39 has been classified as Green List (High Evidence).","entity_name":"CCDC39","entity_type":"gene"},{"created":"2024-10-31T12:32:14.022819+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.526","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CCDC39 were set to ","entity_name":"CCDC39","entity_type":"gene"},{"created":"2024-10-31T12:31:19.164443+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.525","user_name":"Zornitza Stark","item_type":"entity","text":"Tag review tag was added to gene: FYCO1.","entity_name":"FYCO1","entity_type":"gene"},{"created":"2024-10-31T12:30:30.075016+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.525","user_name":"Lucy Spencer","item_type":"entity","text":"edited their review of gene: SPG11: Changed phenotypes: Hereditary spastic paraplegia 11 MONDO:0011445","entity_name":"SPG11","entity_type":"gene"},{"created":"2024-10-31T12:30:09.874873+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.525","user_name":"Lucy Spencer","item_type":"entity","text":"changed review comment from: OMIM:\r\nCharcot-Marie-Tooth disease type 2X (CMT2X) is an autosomal recessive, slowly progressive, axonal peripheral sensorimotor neuropathy characterized by lower limb muscle weakness and atrophy associated with distal sensory impairment and gait difficulties. Some patients also have involvement of the upper limbs. Onset usually occurs in the first 2 decades of life, although later onset can also occur (summary by Montecchiani et al., 2016). Mean age of onset 11.4 years.\r\n\r\nHereditary spastic paraplegia (SPG or HSP) is characterized by progressive weakness and spasticity of the lower limbs due to degeneration of corticospinal axons. SPG11 is a form of complicated SPG, in that it has neurologic features in addition to spasticity.\r\n\r\nClinGen lumps all 3 conditions under spastic paraplegia 11\r\n\r\nAutosomal recessive juvenile amyotrophic lateral sclerosis-5 (ALS5) is a neurodegenerative disorder characterized by onset of upper and lower motor neuron signs before age 25. Affected individuals have progressive spasticity of limb and facial muscles associated with distal amyotrophy. The disorder is slowly progressive, with cases of prolonged survival of more than 3 decades (summary by Orlacchio et al., 2010).; to: OMIM:\r\nCharcot-Marie-Tooth disease type 2X (CMT2X) is an autosomal recessive, slowly progressive, axonal peripheral sensorimotor neuropathy characterized by lower limb muscle weakness and atrophy associated with distal sensory impairment and gait difficulties. Some patients also have involvement of the upper limbs. Onset usually occurs in the first 2 decades of life, although later onset can also occur (summary by Montecchiani et al., 2016). Mean age of onset 11.4 years.\r\n\r\nHereditary spastic paraplegia (SPG or HSP) is characterized by progressive weakness and spasticity of the lower limbs due to degeneration of corticospinal axons. SPG11 is a form of complicated SPG, in that it has neurologic features in addition to spasticity.\r\n\r\nAutosomal recessive juvenile amyotrophic lateral sclerosis-5 (ALS5) is a neurodegenerative disorder characterized by onset of upper and lower motor neuron signs before age 25. Affected individuals have progressive spasticity of limb and facial muscles associated with distal amyotrophy. The disorder is slowly progressive, with cases of prolonged survival of more than 3 decades (summary by Orlacchio et al., 2010).\r\n\r\nThese 3 conditions represent a spectrum of disease and ClinGen lumps all 3 conditions under hereditary spastic paraplegia 11 MONDO:0011445 ","entity_name":"SPG11","entity_type":"gene"},{"created":"2024-10-31T12:30:07.226827+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.525","user_name":"Zornitza Stark","item_type":"entity","text":"Tag founder tag was added to gene: CTPS1.","entity_name":"CTPS1","entity_type":"gene"},{"created":"2024-10-31T12:28:16.048041+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.525","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: DMD as ready","entity_name":"DMD","entity_type":"gene"},{"created":"2024-10-31T12:28:16.027173+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.525","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: dmd has been classified as Green List (High Evidence).","entity_name":"DMD","entity_type":"gene"},{"created":"2024-10-31T12:28:12.227675+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.525","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: DMD were changed from Duchenne muscular dystrophy, 310200 (3) to Becker muscular dystrophy MIM#300376; Duchenne muscular dystrophy MIM#310200","entity_name":"DMD","entity_type":"gene"},{"created":"2024-10-31T12:27:50.654311+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.524","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: DMD were set to ","entity_name":"DMD","entity_type":"gene"},{"created":"2024-10-31T12:27:38.424263+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.523","user_name":"Zornitza Stark","item_type":"entity","text":"Tag SV/CNV tag was added to gene: DMD.","entity_name":"DMD","entity_type":"gene"},{"created":"2024-10-31T12:27:12.105725+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.523","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CTNS as ready","entity_name":"CTNS","entity_type":"gene"},{"created":"2024-10-31T12:27:12.072896+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.523","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ctns has been classified as Green List (High Evidence).","entity_name":"CTNS","entity_type":"gene"},{"created":"2024-10-31T12:27:09.166708+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.523","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CTNS were changed from Cystinosis, nephropathic, 219800 (3) to Cystinosis, nephropathic MIM#219800; Cystinosis, late-onset juvenile or adolescent nephropathic MIM#219900; Cystinosis, atypical nephropathic MIM#219800","entity_name":"CTNS","entity_type":"gene"},{"created":"2024-10-31T12:26:50.067033+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.522","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CTNS were set to ","entity_name":"CTNS","entity_type":"gene"},{"created":"2024-10-31T12:26:19.846241+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.521","user_name":"Zornitza Stark","item_type":"entity","text":"Tag SV/CNV tag was added to gene: CTNS.","entity_name":"CTNS","entity_type":"gene"},{"created":"2024-10-31T12:07:36.023295+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.521","user_name":"Zornitza Stark","item_type":"entity","text":"Tag review tag was added to gene: TSPYL1.","entity_name":"TSPYL1","entity_type":"gene"},{"created":"2024-10-31T11:48:51.109570+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.521","user_name":"Andrew Coventry","item_type":"entity","text":"reviewed gene: GOSR2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29855340 33639315 1549339 23449775 24458321 30838261 32105965; Phenotypes: Epilepsy, progressive myoclonic 6 MIM#614018, Muscular dystrophy, congenital, with or without seizures MIM#620166; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"GOSR2","entity_type":"gene"},{"created":"2024-10-31T11:09:38.026527+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.521","user_name":"Andrew Coventry","item_type":"entity","text":"reviewed gene: GLB1: Rating: GREEN; Mode of pathogenicity: None; Publications: 34539759 24156116 16941474 17309651 25936995 32219518 1928092 33558080 10841810; Phenotypes: GM1-gangliosidosis, type I MIM#230500, GM1-gangliosidosis, type II MIM#230600, GM1-gangliosidosis, type III MIM#230650, Mucopolysaccharidosis type IVB (Morquio) MIM#253010; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"GLB1","entity_type":"gene"},{"created":"2024-10-31T10:25:14.437137+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.2073","user_name":"Eleanor Williams","item_type":"entity","text":"commented on gene: TOMM7","entity_name":"TOMM7","entity_type":"gene"},{"created":"2024-10-30T18:12:29.685748+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.521","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CCDC40 as ready","entity_name":"CCDC40","entity_type":"gene"},{"created":"2024-10-30T18:12:29.659937+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.521","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ccdc40 has been classified as Green List (High Evidence).","entity_name":"CCDC40","entity_type":"gene"},{"created":"2024-10-30T18:12:24.520655+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.521","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CCDC40 were changed from Ciliary dyskinesia, primary, 15, 613808 (3) to Ciliary dyskinesia, primary, 15 MIM#613808","entity_name":"CCDC40","entity_type":"gene"},{"created":"2024-10-30T18:12:13.827589+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.520","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: CCDC40 were set to ","entity_name":"CCDC40","entity_type":"gene"},{"created":"2024-10-30T18:11:48.855725+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.519","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RAPSN as ready","entity_name":"RAPSN","entity_type":"gene"},{"created":"2024-10-30T18:11:48.844841+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.519","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rapsn has been classified as Green List (High Evidence).","entity_name":"RAPSN","entity_type":"gene"},{"created":"2024-10-30T18:11:42.599229+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.519","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RAPSN were changed from Fetal akinesia deformation sequence, 208150 (3) to Myasthenic syndrome, congenital, 11, associated with acetylcholine receptor deficiency MIM#616326; Fetal akinesia deformation sequence 2 MIM#618388","entity_name":"RAPSN","entity_type":"gene"},{"created":"2024-10-30T18:11:31.776300+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.518","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: RAPSN were set to ","entity_name":"RAPSN","entity_type":"gene"},{"created":"2024-10-30T18:11:08.213193+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.517","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: REEP6 as ready","entity_name":"REEP6","entity_type":"gene"},{"created":"2024-10-30T18:11:08.173438+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.517","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: reep6 has been classified as Green List (High Evidence).","entity_name":"REEP6","entity_type":"gene"},{"created":"2024-10-30T18:11:05.455687+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.517","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: REEP6 were changed from Retinitis pigmentosa 77, 617304 (3), Autosomal recessive to Retinitis pigmentosa 77 MIM#617304","entity_name":"REEP6","entity_type":"gene"},{"created":"2024-10-30T18:10:40.895027+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.516","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: REN as ready","entity_name":"REN","entity_type":"gene"},{"created":"2024-10-30T18:10:40.873234+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.516","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ren has been classified as Green List (High Evidence).","entity_name":"REN","entity_type":"gene"},{"created":"2024-10-30T18:10:37.158073+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.516","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: REN were changed from Renal tubular dysgenesis, 267430 (3) to Renal tubular dysgenesis MIM#267430","entity_name":"REN","entity_type":"gene"},{"created":"2024-10-30T18:10:14.191420+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.515","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RLIM as ready","entity_name":"RLIM","entity_type":"gene"},{"created":"2024-10-30T18:10:14.175764+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.515","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rlim has been classified as Green List (High Evidence).","entity_name":"RLIM","entity_type":"gene"},{"created":"2024-10-30T18:10:10.485570+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.515","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RLIM were changed from Mental retardation, X-linked 61, 300978 (3), X-linked recessive to Tonne-Kalscheuer syndrome MIM#300978","entity_name":"RLIM","entity_type":"gene"},{"created":"2024-10-30T18:09:45.362684+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.514","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RTN4IP1 as ready","entity_name":"RTN4IP1","entity_type":"gene"},{"created":"2024-10-30T18:09:45.328777+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.514","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: rtn4ip1 has been classified as Green List (High Evidence).","entity_name":"RTN4IP1","entity_type":"gene"},{"created":"2024-10-30T18:09:42.404893+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.514","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: RTN4IP1 were changed from Optic atrophy 10 with or without ataxia, mental retardation, and seizures, 616732 (3), Autosomal recessive to Optic atrophy 10 with or without ataxia, impaired intellectual development and seizures MIM#616732","entity_name":"RTN4IP1","entity_type":"gene"},{"created":"2024-10-30T18:09:14.728786+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.513","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SCYL1 as ready","entity_name":"SCYL1","entity_type":"gene"},{"created":"2024-10-30T18:09:14.716159+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.513","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: scyl1 has been classified as Green List (High Evidence).","entity_name":"SCYL1","entity_type":"gene"},{"created":"2024-10-30T18:09:10.836944+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.513","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SCYL1 were changed from Spinocerebellar ataxia, autosomal recessive 21, 616719 (3) to Spinocerebellar ataxia, autosomal recessive 21, MIM#616719","entity_name":"SCYL1","entity_type":"gene"},{"created":"2024-10-30T18:08:34.296929+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.512","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SH3TC2 as ready","entity_name":"SH3TC2","entity_type":"gene"},{"created":"2024-10-30T18:08:34.281115+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.512","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: sh3tc2 has been classified as Green List (High Evidence).","entity_name":"SH3TC2","entity_type":"gene"},{"created":"2024-10-30T18:08:31.251208+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.512","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SH3TC2 were changed from Charcot-Marie-Tooth disease, type 4C, 601596 (3) to Charcot-Marie-Tooth disease, type 4C, MIM#601596","entity_name":"SH3TC2","entity_type":"gene"},{"created":"2024-10-30T18:07:18.892533+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.511","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SPINK5 as ready","entity_name":"SPINK5","entity_type":"gene"},{"created":"2024-10-30T18:07:18.872384+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.511","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: spink5 has been classified as Green List (High Evidence).","entity_name":"SPINK5","entity_type":"gene"},{"created":"2024-10-30T18:07:14.239346+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.511","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SPINK5 were changed from Netherton syndrome, 256500 (3) to Netherton syndrome MIM#256500","entity_name":"SPINK5","entity_type":"gene"},{"created":"2024-10-30T18:06:51.944031+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.510","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SUCLA2 as ready","entity_name":"SUCLA2","entity_type":"gene"},{"created":"2024-10-30T18:06:51.932206+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.510","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: sucla2 has been classified as Green List (High Evidence).","entity_name":"SUCLA2","entity_type":"gene"},{"created":"2024-10-30T18:06:48.333542+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.510","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SUCLA2 were changed from Mitochondrial DNA depletion syndrome 5 (encephalomyopathic with or without methylmalonic aciduria), 612073 (3) to Mitochondrial DNA depletion syndrome 5 (encephalomyopathic with or without methylmalonic aciduria), MIM#612073","entity_name":"SUCLA2","entity_type":"gene"},{"created":"2024-10-30T18:06:14.209933+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.509","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TANGO2 as ready","entity_name":"TANGO2","entity_type":"gene"},{"created":"2024-10-30T18:06:14.179643+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.509","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tango2 has been classified as Green List (High Evidence).","entity_name":"TANGO2","entity_type":"gene"},{"created":"2024-10-30T18:06:09.203597+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.509","user_name":"Zornitza Stark","item_type":"entity","text":"Tag SV/CNV tag was added to gene: TANGO2.","entity_name":"TANGO2","entity_type":"gene"},{"created":"2024-10-30T18:05:24.516395+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.509","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: DNAAF3 as ready","entity_name":"DNAAF3","entity_type":"gene"},{"created":"2024-10-30T18:05:24.486721+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.509","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: dnaaf3 has been classified as Green List (High Evidence).","entity_name":"DNAAF3","entity_type":"gene"},{"created":"2024-10-30T18:05:21.135133+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.509","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: DNAAF3 were changed from Ciliary dyskinesia, primary, 2, 606763 (3) to Ciliary dyskinesia, primary, 2, MIM#606763","entity_name":"DNAAF3","entity_type":"gene"},{"created":"2024-10-30T18:05:10.526097+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.508","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: DNAAF3 were set to ","entity_name":"DNAAF3","entity_type":"gene"},{"created":"2024-10-30T18:04:20.131730+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.507","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: EXTL3 as ready","entity_name":"EXTL3","entity_type":"gene"},{"created":"2024-10-30T18:04:20.105974+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.507","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: extl3 has been classified as Green List (High Evidence).","entity_name":"EXTL3","entity_type":"gene"},{"created":"2024-10-30T18:04:17.071075+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.507","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: EXTL3 were changed from Immunoskeletal dysplasia with neurodevelopmental abnormalities, 617425 (3), Autosomal recessive to Immunoskeletal dysplasia with neurodevelopmental abnormalities, MIM#617425","entity_name":"EXTL3","entity_type":"gene"},{"created":"2024-10-30T18:03:57.045089+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.506","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: EXTL3 were set to ","entity_name":"EXTL3","entity_type":"gene"},{"created":"2024-10-30T18:03:27.029316+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.505","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FANCF as ready","entity_name":"FANCF","entity_type":"gene"},{"created":"2024-10-30T18:03:27.000441+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.505","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fancf has been classified as Green List (High Evidence).","entity_name":"FANCF","entity_type":"gene"},{"created":"2024-10-30T18:03:24.228808+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.505","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FANCF were changed from Fanconi anemia, complementation group F, 603467 (3) to Fanconi anaemia, complementation group F, MIM#603467","entity_name":"FANCF","entity_type":"gene"},{"created":"2024-10-30T18:03:09.610993+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.504","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: FANCF were set to ","entity_name":"FANCF","entity_type":"gene"},{"created":"2024-10-30T18:02:39.527289+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.503","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FOLR1 as ready","entity_name":"FOLR1","entity_type":"gene"},{"created":"2024-10-30T18:02:39.515319+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.503","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: folr1 has been classified as Green List (High Evidence).","entity_name":"FOLR1","entity_type":"gene"},{"created":"2024-10-30T18:02:35.849799+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.503","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FOLR1 were changed from Neurodegeneration due to cerebral folate transport deficiency, 613068 (3) to Neurodegeneration due to cerebral folate transport deficiency, MIM#613068","entity_name":"FOLR1","entity_type":"gene"},{"created":"2024-10-30T18:02:21.552364+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.502","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: FOLR1 were set to ","entity_name":"FOLR1","entity_type":"gene"},{"created":"2024-10-30T18:01:54.995931+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.501","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: GFPT1 as ready","entity_name":"GFPT1","entity_type":"gene"},{"created":"2024-10-30T18:01:54.975484+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.501","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: gfpt1 has been classified as Green List (High Evidence).","entity_name":"GFPT1","entity_type":"gene"},{"created":"2024-10-30T18:01:45.198735+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.501","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: GFPT1 were changed from Myasthenia, congenital, 12, with tubular aggregates, 610542 (3) to Myasthenia, congenital, 12, with tubular aggregates, MIM#610542","entity_name":"GFPT1","entity_type":"gene"},{"created":"2024-10-30T18:01:29.491635+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.500","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: GFPT1 were set to ","entity_name":"GFPT1","entity_type":"gene"},{"created":"2024-10-30T18:00:03.561537+11:00","panel_name":"Skeletal dysplasia","panel_id":258,"panel_version":"0.289","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: DDX41 as ready","entity_name":"DDX41","entity_type":"gene"},{"created":"2024-10-30T18:00:03.540762+11:00","panel_name":"Skeletal dysplasia","panel_id":258,"panel_version":"0.289","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ddx41 has been classified as Red List (Low Evidence).","entity_name":"DDX41","entity_type":"gene"},{"created":"2024-10-30T17:59:42.296584+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.499","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: CLRN1 as ready","entity_name":"CLRN1","entity_type":"gene"},{"created":"2024-10-30T17:59:42.278026+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.499","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: clrn1 has been classified as Green List (High Evidence).","entity_name":"CLRN1","entity_type":"gene"},{"created":"2024-10-30T17:59:39.374636+11:00","panel_name":"Prepair 1000+","panel_id":3861,"panel_version":"1.499","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: CLRN1 were changed from Usher syndrome, type 3A, 276902 (3) to Usher syndrome, type 3A (MIM#276902)","entity_name":"CLRN1","entity_type":"gene"}]}