{"count":221415,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=376","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=374","results":[{"created":"2024-10-03T18:01:19.374809+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6365","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NPC2 as ready","entity_name":"NPC2","entity_type":"gene"},{"created":"2024-10-03T18:01:19.361511+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6365","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: npc2 has been classified as Green List (High Evidence).","entity_name":"NPC2","entity_type":"gene"},{"created":"2024-10-03T18:00:57.875153+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6365","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NPC2 were changed from  to Niemann-pick disease, type C2, MIM# 607625; MONDO:0011873","entity_name":"NPC2","entity_type":"gene"},{"created":"2024-10-03T18:00:07.700478+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6364","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NPC2 were set to 11125141; 17470133","entity_name":"NPC2","entity_type":"gene"},{"created":"2024-10-03T17:59:17.995594+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6363","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NPC2 were set to ","entity_name":"NPC2","entity_type":"gene"},{"created":"2024-10-03T17:58:25.513287+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6362","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NPC2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NPC2","entity_type":"gene"},{"created":"2024-10-03T17:57:31.235080+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6361","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NPC1 as ready","entity_name":"NPC1","entity_type":"gene"},{"created":"2024-10-03T17:57:31.217325+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6361","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: npc1 has been classified as Green List (High Evidence).","entity_name":"NPC1","entity_type":"gene"},{"created":"2024-10-03T17:57:18.683716+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6361","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NPC1 were changed from  to Niemann-Pick disease, type C1 and type D, MIM# 257220; MONDO:0009757","entity_name":"NPC1","entity_type":"gene"},{"created":"2024-10-03T17:56:38.157162+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6360","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NPC1 were set to ","entity_name":"NPC1","entity_type":"gene"},{"created":"2024-10-03T17:55:55.112691+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6359","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NPC1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NPC1","entity_type":"gene"},{"created":"2024-10-03T17:54:18.178575+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6358","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NKX2-1 as ready","entity_name":"NKX2-1","entity_type":"gene"},{"created":"2024-10-03T17:54:18.151679+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6358","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nkx2-1 has been classified as Green List (High Evidence).","entity_name":"NKX2-1","entity_type":"gene"},{"created":"2024-10-03T17:54:05.437284+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6358","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NKX2-1 were changed from Choreoathetosis, hypothyroidism, and neonatal respiratory distress MIM#610978 to Choreoathetosis, hypothyroidism, and neonatal respiratory distress MIM#610978","entity_name":"NKX2-1","entity_type":"gene"},{"created":"2024-10-03T17:49:36.387504+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6357","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NKX2-1 were changed from  to Choreoathetosis, hypothyroidism, and neonatal respiratory distress MIM#610978","entity_name":"NKX2-1","entity_type":"gene"},{"created":"2024-10-03T17:48:47.789564+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6356","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NKX2-1 were set to 10931427; 27066577; 26839702; 26103969; 23911641; 11854319; 24714694","entity_name":"NKX2-1","entity_type":"gene"},{"created":"2024-10-03T17:45:58.239724+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6355","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NKX2-1 were set to ","entity_name":"NKX2-1","entity_type":"gene"},{"created":"2024-10-03T17:44:50.775698+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6354","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NKX2-1 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NKX2-1","entity_type":"gene"},{"created":"2024-10-03T17:43:46.559127+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6353","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NGLY1 as ready","entity_name":"NGLY1","entity_type":"gene"},{"created":"2024-10-03T17:43:46.544532+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6353","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ngly1 has been classified as Green List (High Evidence).","entity_name":"NGLY1","entity_type":"gene"},{"created":"2024-10-03T17:43:40.208189+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6353","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NGLY1 were changed from  to Congenital disorder of deglycosylation (OMIM 615273)","entity_name":"NGLY1","entity_type":"gene"},{"created":"2024-10-03T17:42:50.742226+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6352","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: NGLY1: Rating: GREEN; Mode of pathogenicity: None; Publications: 24651605, 27388694, 32259258; Phenotypes: Congenital disorder of deglycosylation (OMIM 615273); Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"NGLY1","entity_type":"gene"},{"created":"2024-10-03T17:42:20.149338+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6352","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NGLY1 were set to ","entity_name":"NGLY1","entity_type":"gene"},{"created":"2024-10-03T17:41:27.172025+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6351","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NGLY1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NGLY1","entity_type":"gene"},{"created":"2024-10-03T17:40:28.469103+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6350","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NFIX as ready","entity_name":"NFIX","entity_type":"gene"},{"created":"2024-10-03T17:40:28.438263+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6350","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nfix has been classified as Green List (High Evidence).","entity_name":"NFIX","entity_type":"gene"},{"created":"2024-10-03T17:40:15.399895+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6350","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NFIX were changed from  to Sotos syndrome 2 (MIM#614753); Marshall-Smith syndrome, MIM# 602535","entity_name":"NFIX","entity_type":"gene"},{"created":"2024-10-03T17:39:27.944812+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6349","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NFIX were set to 33034087; 29897170; 30548146; 25118028","entity_name":"NFIX","entity_type":"gene"},{"created":"2024-10-03T17:38:35.979773+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6348","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NFIX were set to ","entity_name":"NFIX","entity_type":"gene"},{"created":"2024-10-03T17:37:25.449642+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6347","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NFIX was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"NFIX","entity_type":"gene"},{"created":"2024-10-03T17:36:29.787010+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6346","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NEU1 as ready","entity_name":"NEU1","entity_type":"gene"},{"created":"2024-10-03T17:36:29.773373+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6346","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: neu1 has been classified as Green List (High Evidence).","entity_name":"NEU1","entity_type":"gene"},{"created":"2024-10-03T17:36:20.271196+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6346","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NEU1 were changed from  to Sialidosis, type I and type II, MIM# 256550; MONDO:0009738","entity_name":"NEU1","entity_type":"gene"},{"created":"2024-10-03T17:32:31.960070+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6345","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NEU1 were set to ","entity_name":"NEU1","entity_type":"gene"},{"created":"2024-10-03T17:31:43.080889+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6344","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NEU1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NEU1","entity_type":"gene"},{"created":"2024-10-03T17:30:47.042267+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6343","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDUFV1 as ready","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2024-10-03T17:30:47.026961+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6343","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ndufv1 has been classified as Green List (High Evidence).","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2024-10-03T17:30:39.839361+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6343","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFV1 were changed from  to Mitochondrial complex I deficiency, nuclear type 4 MIM#618225","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2024-10-03T17:29:36.754829+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6342","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDUFV1 were set to ","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2024-10-03T17:28:58.246796+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6341","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDUFV1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2024-10-03T17:28:08.633172+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6340","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDUFS7 as ready","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2024-10-03T17:28:08.607651+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6340","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ndufs7 has been classified as Green List (High Evidence).","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2024-10-03T17:28:04.592763+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6340","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFS7 were changed from  to Mitochondrial complex I deficiency, nuclear type 3 (MIM# 618224)","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2024-10-03T17:27:11.334918+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6339","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDUFS7 were set to ","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2024-10-03T17:26:32.241992+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6338","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDUFS7 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2024-10-03T17:25:32.624600+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6337","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDUFA1 as ready","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2024-10-03T17:25:32.592920+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6337","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ndufa1 has been classified as Green List (High Evidence).","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2024-10-03T17:25:26.212928+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6337","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFA1 were changed from Mitochondrial complex I deficiency, nuclear type 12 MIM#301020 to Mitochondrial complex I deficiency, nuclear type 12 MIM#301020","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2024-10-03T17:24:50.356038+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6336","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFA1 were changed from  to Mitochondrial complex I deficiency, nuclear type 12 MIM#301020","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2024-10-03T17:24:07.998073+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6335","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDUFA1 were set to ","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2024-10-03T17:20:25.529211+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6334","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDUFA1 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2024-10-03T17:18:58.774371+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6333","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NALCN as ready","entity_name":"NALCN","entity_type":"gene"},{"created":"2024-10-03T17:18:58.759475+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6333","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: nalcn has been classified as Green List (High Evidence).","entity_name":"NALCN","entity_type":"gene"},{"created":"2024-10-03T17:18:49.405139+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6333","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NALCN were changed from  to Congenital contractures of the limbs and face, hypotonia, and developmental delay, MIM# 616266; Hypotonia, infantile, with psychomotor retardation and characteristic facies 1, MIM # 615419","entity_name":"NALCN","entity_type":"gene"},{"created":"2024-10-03T17:11:51.768405+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6332","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NALCN were set to ","entity_name":"NALCN","entity_type":"gene"},{"created":"2024-10-03T17:11:00.229675+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6331","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NALCN was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"NALCN","entity_type":"gene"},{"created":"2024-10-03T17:10:00.376314+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6330","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NAGLU as ready","entity_name":"NAGLU","entity_type":"gene"},{"created":"2024-10-03T17:10:00.344510+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6330","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: naglu has been classified as Green List (High Evidence).","entity_name":"NAGLU","entity_type":"gene"},{"created":"2024-10-03T17:09:50.722957+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6330","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NAGLU were changed from  to Mucopolysaccharidosis type IIIB (Sanfilippo B), MIM# 252920","entity_name":"NAGLU","entity_type":"gene"},{"created":"2024-10-03T17:09:11.833849+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6329","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NAGLU were set to ","entity_name":"NAGLU","entity_type":"gene"},{"created":"2024-10-03T17:08:10.732057+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6328","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NAGLU was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NAGLU","entity_type":"gene"},{"created":"2024-10-03T17:03:05.089128+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6327","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NAGA as ready","entity_name":"NAGA","entity_type":"gene"},{"created":"2024-10-03T17:03:05.067697+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6327","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: naga has been classified as Green List (High Evidence).","entity_name":"NAGA","entity_type":"gene"},{"created":"2024-10-03T17:02:16.431040+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6327","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NAGA were changed from Kanzaki disease, MIM# 609242; Schindler disease, type I and type II 609241; alpha-N-acetylgalactosaminidase deficiency MONDO:0017779 to Kanzaki disease, MIM# 609242; Schindler disease, type I and type II 609241; alpha-N-acetylgalactosaminidase deficiency MONDO:0017779","entity_name":"NAGA","entity_type":"gene"},{"created":"2024-10-03T17:01:52.410798+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6327","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NAGA were changed from  to Kanzaki disease, MIM# 609242; Schindler disease, type I and type II 609241; alpha-N-acetylgalactosaminidase deficiency MONDO:0017779","entity_name":"NAGA","entity_type":"gene"},{"created":"2024-10-03T17:00:56.896422+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6326","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NAGA were set to ","entity_name":"NAGA","entity_type":"gene"},{"created":"2024-10-03T16:59:59.584365+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6325","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NAGA was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NAGA","entity_type":"gene"},{"created":"2024-10-03T16:58:55.876007+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6324","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SCO2 as ready","entity_name":"SCO2","entity_type":"gene"},{"created":"2024-10-03T16:58:55.846188+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6324","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: sco2 has been classified as Green List (High Evidence).","entity_name":"SCO2","entity_type":"gene"},{"created":"2024-10-03T16:58:50.614800+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6324","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SCO2 were changed from  to Mitochondrial complex IV deficiency, nuclear type 2, MIM# 604377","entity_name":"SCO2","entity_type":"gene"},{"created":"2024-10-03T16:58:08.835336+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6323","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SCO2 were set to ","entity_name":"SCO2","entity_type":"gene"},{"created":"2024-10-03T16:57:25.282263+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6322","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SCO2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"SCO2","entity_type":"gene"},{"created":"2024-10-03T16:55:47.673307+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6321","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SKI as ready","entity_name":"SKI","entity_type":"gene"},{"created":"2024-10-03T16:55:47.605493+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6321","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ski has been classified as Green List (High Evidence).","entity_name":"SKI","entity_type":"gene"},{"created":"2024-10-03T16:55:36.916868+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6321","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SKI were changed from  to Shprintzen-Goldberg syndrome, MIM# 182212; Neurodevelopmental disorder, MONDO:0700092, SKI-related","entity_name":"SKI","entity_type":"gene"},{"created":"2024-10-03T16:55:02.212191+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6320","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SKI were set to ","entity_name":"SKI","entity_type":"gene"},{"created":"2024-10-03T16:50:01.648918+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6319","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SKI was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SKI","entity_type":"gene"},{"created":"2024-10-03T16:49:17.424368+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6318","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: SKI: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Neurodevelopmental disorder, MONDO:0700092, SKI-related; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SKI","entity_type":"gene"},{"created":"2024-10-03T16:47:41.987840+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6318","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: SHH as ready","entity_name":"SHH","entity_type":"gene"},{"created":"2024-10-03T16:47:41.973272+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6318","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: shh has been classified as Green List (High Evidence).","entity_name":"SHH","entity_type":"gene"},{"created":"2024-10-03T16:47:34.812512+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6318","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: SHH were changed from  to Holoprosencephaly 3 (MIM#142945)","entity_name":"SHH","entity_type":"gene"},{"created":"2024-10-03T16:46:41.050910+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6317","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: SHH were set to ","entity_name":"SHH","entity_type":"gene"},{"created":"2024-10-03T16:45:03.908865+10:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.6316","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: SHH was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"SHH","entity_type":"gene"},{"created":"2024-10-03T16:43:52.360561+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.2047","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: IL7 as ready","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:43:52.348221+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.2047","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: il7 has been classified as Green List (High Evidence).","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:43:39.181549+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.2047","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: IL7 as Green List (high evidence)","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:43:39.161165+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.2047","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: il7 has been classified as Green List (High Evidence).","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:43:12.589137+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.2046","user_name":"Zornitza Stark","item_type":"entity","text":"gene: IL7 was added\ngene: IL7 was added to Mendeliome. Sources: Literature\nMode of inheritance for gene: IL7 was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: IL7 were set to 39352394\nPhenotypes for gene: IL7 were set to Combined immunodeficiency, MONDO:0015131, IL7-related\nReview for gene: IL7 was set to GREEN\nAdded comment: 6 indviduals from 4 kindreds with combined immune deficiency and recurrent infections. Extensive immunophenotyping revealing IL7 dependent and independent development of T cells. \nSources: Literature","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:42:40.415831+10:00","panel_name":"Combined Immunodeficiency","panel_id":223,"panel_version":"1.73","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: IL7 as ready","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:42:40.404849+10:00","panel_name":"Combined Immunodeficiency","panel_id":223,"panel_version":"1.73","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: il7 has been classified as Green List (High Evidence).","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:41:36.590147+10:00","panel_name":"Combined Immunodeficiency","panel_id":223,"panel_version":"1.73","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: IL7 were changed from Combined Immune deficiency to Combined immunodeficiency, MONDO:0015131, IL7-related","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:40:37.059924+10:00","panel_name":"Combined Immunodeficiency","panel_id":223,"panel_version":"1.72","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: IL7 as Green List (high evidence)","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:40:37.050785+10:00","panel_name":"Combined Immunodeficiency","panel_id":223,"panel_version":"1.72","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: il7 has been classified as Green List (High Evidence).","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:40:00.404621+10:00","panel_name":"Combined Immunodeficiency","panel_id":223,"panel_version":"1.71","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: IL7: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Combined immunodeficiency, MONDO:0015131, IL7-related; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"IL7","entity_type":"gene"},{"created":"2024-10-03T16:37:28.930305+10:00","panel_name":"Severe early-onset obesity","panel_id":3764,"panel_version":"1.12","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LRRC7 as ready","entity_name":"LRRC7","entity_type":"gene"},{"created":"2024-10-03T16:37:28.916636+10:00","panel_name":"Severe early-onset obesity","panel_id":3764,"panel_version":"1.12","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lrrc7 has been classified as Green List (High Evidence).","entity_name":"LRRC7","entity_type":"gene"},{"created":"2024-10-03T16:37:16.394315+10:00","panel_name":"Severe early-onset obesity","panel_id":3764,"panel_version":"1.12","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: LRRC7 as Green List (high evidence)","entity_name":"LRRC7","entity_type":"gene"},{"created":"2024-10-03T16:37:16.378974+10:00","panel_name":"Severe early-onset obesity","panel_id":3764,"panel_version":"1.12","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lrrc7 has been classified as Green List (High Evidence).","entity_name":"LRRC7","entity_type":"gene"},{"created":"2024-10-03T16:36:57.076036+10:00","panel_name":"Severe early-onset obesity","panel_id":3764,"panel_version":"1.11","user_name":"Zornitza Stark","item_type":"entity","text":"gene: LRRC7 was added\ngene: LRRC7 was added to Severe early-onset obesity. Sources: Literature\nMode of inheritance for gene: LRRC7 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPublications for gene: LRRC7 were set to 39256359\nPhenotypes for gene: LRRC7 were set to neurodevelopmental disorder (MONDO:0700092), LRRC7-related\nReview for gene: LRRC7 was set to GREEN\nAdded comment: Over 30 individuals reported with a neurodevelopmental disorder and variants in this gene. Hyperphagia and early-onset obesity is a common feature. \nSources: Literature","entity_name":"LRRC7","entity_type":"gene"},{"created":"2024-10-03T16:36:10.876065+10:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.2045","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LRRC7 as ready","entity_name":"LRRC7","entity_type":"gene"}]}