{"count":221276,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=688","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=686","results":[{"created":"2022-11-23T17:30:38.563871+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1050","user_name":"Zornitza Stark","item_type":"entity","text":"Tag for review was removed from gene: TSC1.","entity_name":"TSC1","entity_type":"gene"},{"created":"2022-11-23T17:30:29.708989+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1050","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TSC1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Tuberous sclerosis-1 MIM#191100; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"TSC1","entity_type":"gene"},{"created":"2022-11-23T17:29:46.052428+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1050","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TSC2 as Red List (low evidence)","entity_name":"TSC2","entity_type":"gene"},{"created":"2022-11-23T17:29:46.040646+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1050","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tsc2 has been classified as Red List (Low Evidence).","entity_name":"TSC2","entity_type":"gene"},{"created":"2022-11-23T17:29:36.991015+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1049","user_name":"Zornitza Stark","item_type":"entity","text":"Tag for review was removed from gene: TSC2.","entity_name":"TSC2","entity_type":"gene"},{"created":"2022-11-23T17:29:27.603081+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1049","user_name":"Zornitza Stark","item_type":"entity","text":"changed review comment from: Treatment is largely symptomatic.; to: Treatment is symptomatic.","entity_name":"TSC2","entity_type":"gene"},{"created":"2022-11-23T17:29:19.229085+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1049","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TSC2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Tuberous sclerosis-2 MIM#613254; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"TSC2","entity_type":"gene"},{"created":"2022-11-23T17:25:02.135180+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1049","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: TTC7A as Red List (low evidence)","entity_name":"TTC7A","entity_type":"gene"},{"created":"2022-11-23T17:25:02.116941+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1049","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ttc7a has been classified as Red List (Low Evidence).","entity_name":"TTC7A","entity_type":"gene"},{"created":"2022-11-23T17:24:52.503359+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1048","user_name":"Zornitza Stark","item_type":"entity","text":"Tag for review was removed from gene: TTC7A.","entity_name":"TTC7A","entity_type":"gene"},{"created":"2022-11-23T17:24:43.959573+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1048","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TTC7A: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Gastrointestinal defects and immunodeficiency syndrome MIM#243150; Mode of inheritance: None","entity_name":"TTC7A","entity_type":"gene"},{"created":"2022-11-23T17:17:48.769221+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1048","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: ERCC2 as Red List (low evidence)","entity_name":"ERCC2","entity_type":"gene"},{"created":"2022-11-23T17:17:48.754278+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1048","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ercc2 has been classified as Red List (Low Evidence).","entity_name":"ERCC2","entity_type":"gene"},{"created":"2022-11-23T17:17:39.264319+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1047","user_name":"Zornitza Stark","item_type":"entity","text":"Tag for review was removed from gene: ERCC2.","entity_name":"ERCC2","entity_type":"gene"},{"created":"2022-11-23T17:17:12.309610+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1047","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: ERCC2: Changed rating: RED","entity_name":"ERCC2","entity_type":"gene"},{"created":"2022-11-23T17:17:03.834169+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1047","user_name":"Zornitza Stark","item_type":"entity","text":"changed review comment from: Bi-allelic variants in this gene cause a range of conditions, including COFS, trichothiodystrophy and XPE.\r\n\r\nDNA repair disorder.\r\n\r\nSome features are treatable: avoid exposure to UVA and UVB (found in sunlight) and UVC (found in some artificial light sources). Oral isotretinoin, oral niacinamide, topical imiquimod and topical fluorouracil.\r\n\r\nFor discussion.; to: Bi-allelic variants in this gene cause a range of conditions, including COFS, trichothiodystrophy and XPE.\r\n\r\nDNA repair disorder.\r\n\r\nSome features are treatable: avoid exposure to UVA and UVB (found in sunlight) and UVC (found in some artificial light sources). Oral isotretinoin, oral niacinamide, topical imiquimod and topical fluorouracil.\r\n","entity_name":"ERCC2","entity_type":"gene"},{"created":"2022-11-23T17:15:48.861730+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1047","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TSHR were changed from Hypothyroidism, congenital, nongoitrous, 1 - MIM#275200 to Hypothyroidism, congenital, nongoitrous, 1 - MIM#275200; HYPERTHYROIDISM, FAMILIAL GESTATIONAL HYPERTHYROIDISM","entity_name":"TSHR","entity_type":"gene"},{"created":"2022-11-23T17:15:27.696148+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1046","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TSHR was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"TSHR","entity_type":"gene"},{"created":"2022-11-23T17:13:32.777852+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1045","user_name":"Zornitza Stark","item_type":"entity","text":"Tag for review was removed from gene: FLCN.","entity_name":"FLCN","entity_type":"gene"},{"created":"2022-11-23T17:11:52.683676+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1045","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: FBN1 as Amber List (moderate evidence)","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T17:11:52.671738+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1045","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fbn1 has been classified as Amber List (Moderate Evidence).","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T17:11:38.401928+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1044","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: FBN1: Changed rating: AMBER","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T17:04:57.857507+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1044","user_name":"Zornitza Stark","item_type":"entity","text":"Tag clinical trial tag was added to gene: FGFR3.","entity_name":"FGFR3","entity_type":"gene"},{"created":"2022-11-23T16:59:32.393868+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1044","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FAM161A as ready","entity_name":"FAM161A","entity_type":"gene"},{"created":"2022-11-23T16:59:32.381357+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1044","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fam161a has been classified as Red List (Low Evidence).","entity_name":"FAM161A","entity_type":"gene"},{"created":"2022-11-23T16:59:28.417452+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1044","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FAM161A were changed from Retinal dystrophy to Retinitis pigmentosa 28, 606068","entity_name":"FAM161A","entity_type":"gene"},{"created":"2022-11-23T16:57:56.949318+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1043","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: FAM161A as Red List (low evidence)","entity_name":"FAM161A","entity_type":"gene"},{"created":"2022-11-23T16:57:56.936771+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1043","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fam161a has been classified as Red List (Low Evidence).","entity_name":"FAM161A","entity_type":"gene"},{"created":"2022-11-23T16:57:45.347334+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1042","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FAM161A: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Retinitis pigmentosa 28, 606068; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FAM161A","entity_type":"gene"},{"created":"2022-11-23T16:53:18.788874+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1042","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FAM20C as ready","entity_name":"FAM20C","entity_type":"gene"},{"created":"2022-11-23T16:53:18.770367+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1042","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fam20c has been classified as Red List (Low Evidence).","entity_name":"FAM20C","entity_type":"gene"},{"created":"2022-11-23T16:53:14.914063+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1042","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FAM20C were changed from Osteosclerotic bone dysplasia to Raine syndrome, MIM# 259775","entity_name":"FAM20C","entity_type":"gene"},{"created":"2022-11-23T16:53:02.862102+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1041","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: FAM20C as Red List (low evidence)","entity_name":"FAM20C","entity_type":"gene"},{"created":"2022-11-23T16:53:02.837374+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1041","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fam20c has been classified as Red List (Low Evidence).","entity_name":"FAM20C","entity_type":"gene"},{"created":"2022-11-23T16:52:50.270301+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1040","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FAM20C: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Raine syndrome, MIM# 259775; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FAM20C","entity_type":"gene"},{"created":"2022-11-23T15:49:23.694342+11:00","panel_name":"Genetic Epilepsy","panel_id":202,"panel_version":"0.1803","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: GPHN were set to 22040219; 11095995; 26613940; 24561070; 23393157","entity_name":"GPHN","entity_type":"gene"},{"created":"2022-11-23T15:47:55.278068+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1040","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: ACAT1.","entity_name":"ACAT1","entity_type":"gene"},{"created":"2022-11-23T15:43:01.925535+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1040","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FAM58A as ready","entity_name":"FAM58A","entity_type":"gene"},{"created":"2022-11-23T15:43:01.912058+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1040","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fam58a has been classified as Red List (Low Evidence).","entity_name":"FAM58A","entity_type":"gene"},{"created":"2022-11-23T15:42:49.316536+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1040","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FAM58A were changed from Syndactyly - telecanthus - anogenital and renal malformations to syndactyly-telecanthus-anogenital and renal malformations syndrome MONDO:0010408","entity_name":"FAM58A","entity_type":"gene"},{"created":"2022-11-23T15:42:35.194338+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1039","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: FAM58A as Red List (low evidence)","entity_name":"FAM58A","entity_type":"gene"},{"created":"2022-11-23T15:42:35.182587+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1039","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fam58a has been classified as Red List (Low Evidence).","entity_name":"FAM58A","entity_type":"gene"},{"created":"2022-11-23T15:42:15.451683+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1038","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FAM58A: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: syndactyly-telecanthus-anogenital and renal malformations syndrome MONDO:0010408; Mode of inheritance: Other","entity_name":"FAM58A","entity_type":"gene"},{"created":"2022-11-23T15:39:45.949694+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1038","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FANCA as ready","entity_name":"FANCA","entity_type":"gene"},{"created":"2022-11-23T15:39:45.937371+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1038","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fanca has been classified as Green List (High Evidence).","entity_name":"FANCA","entity_type":"gene"},{"created":"2022-11-23T15:39:42.440018+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1038","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FANCA were changed from Fanconi anaemia, MIM#227650 to Fanconi anaemia, complementation group A, MIM# 227650; MONDO:0009215","entity_name":"FANCA","entity_type":"gene"},{"created":"2022-11-23T15:39:24.938963+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1037","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FANCA: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Fanconi anaemia, complementation group A, MIM# 227650, MONDO:0009215; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FANCA","entity_type":"gene"},{"created":"2022-11-23T15:38:07.446630+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1037","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FANCB as ready","entity_name":"FANCB","entity_type":"gene"},{"created":"2022-11-23T15:38:07.433436+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1037","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fancb has been classified as Green List (High Evidence).","entity_name":"FANCB","entity_type":"gene"},{"created":"2022-11-23T15:38:03.906477+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1037","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FANCB were changed from Fanconi anaemia, MIM#300514 to Fanconi anaemia, complementation group B, MIM# 300514","entity_name":"FANCB","entity_type":"gene"},{"created":"2022-11-23T15:37:49.651857+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1036","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: FANCB.","entity_name":"FANCB","entity_type":"gene"},{"created":"2022-11-23T15:37:39.994594+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1036","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FANCB: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Fanconi anaemia, complementation group B, MIM# 300514; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"FANCB","entity_type":"gene"},{"created":"2022-11-23T15:36:13.571046+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1036","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FANCC as ready","entity_name":"FANCC","entity_type":"gene"},{"created":"2022-11-23T15:36:13.558283+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1036","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fancc has been classified as Green List (High Evidence).","entity_name":"FANCC","entity_type":"gene"},{"created":"2022-11-23T15:36:10.093456+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1036","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FANCC were changed from Fanconi anaemia, MIM#227645 to Fanconi anemia, complementation group C, MIM# 227645; MONDO:0009213","entity_name":"FANCC","entity_type":"gene"},{"created":"2022-11-23T15:35:46.071533+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1035","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FANCC: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Fanconi anemia, complementation group C, MIM# 227645 MONDO:0009213; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FANCC","entity_type":"gene"},{"created":"2022-11-23T15:34:51.361300+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1035","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FANCD2 as ready","entity_name":"FANCD2","entity_type":"gene"},{"created":"2022-11-23T15:34:51.347647+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1035","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fancd2 has been classified as Green List (High Evidence).","entity_name":"FANCD2","entity_type":"gene"},{"created":"2022-11-23T15:33:55.962497+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1035","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FANCD2 were changed from Fanconi anaemia, MIM#227646 to Fanconi anaemia, complementation group D2, MIM# 227646; MONDO:0009214","entity_name":"FANCD2","entity_type":"gene"},{"created":"2022-11-23T15:33:37.649599+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FANCD2: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Fanconi anaemia, complementation group D2, MIM# 227646, MONDO:0009214; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FANCD2","entity_type":"gene"},{"created":"2022-11-23T15:32:21.152732+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FANCG as ready","entity_name":"FANCG","entity_type":"gene"},{"created":"2022-11-23T15:32:21.140462+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fancg has been classified as Green List (High Evidence).","entity_name":"FANCG","entity_type":"gene"},{"created":"2022-11-23T15:32:13.431394+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: FANCG.","entity_name":"FANCG","entity_type":"gene"},{"created":"2022-11-23T15:32:01.995075+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FANCG: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Fanconi anaemia, complementation group G, MIM# 614082, MONDO:0013565; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FANCG","entity_type":"gene"},{"created":"2022-11-23T15:31:17.135270+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FANCI as ready","entity_name":"FANCI","entity_type":"gene"},{"created":"2022-11-23T15:31:17.122224+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fanci has been classified as Green List (High Evidence).","entity_name":"FANCI","entity_type":"gene"},{"created":"2022-11-23T15:31:08.183040+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: FANCI.","entity_name":"FANCI","entity_type":"gene"},{"created":"2022-11-23T15:30:58.845044+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FANCI: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Fanconi anemia, complementation group I, MIM# 609053; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FANCI","entity_type":"gene"},{"created":"2022-11-23T15:28:25.290153+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FAS as ready","entity_name":"FAS","entity_type":"gene"},{"created":"2022-11-23T15:28:25.278144+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fas has been classified as Red List (Low Evidence).","entity_name":"FAS","entity_type":"gene"},{"created":"2022-11-23T15:28:20.209697+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: FAS as Red List (low evidence)","entity_name":"FAS","entity_type":"gene"},{"created":"2022-11-23T15:28:20.193506+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1034","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fas has been classified as Red List (Low Evidence).","entity_name":"FAS","entity_type":"gene"},{"created":"2022-11-23T15:28:07.227040+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1033","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FAS: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Autoimmune lymphoproliferative syndrome MONDO:0017979; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"FAS","entity_type":"gene"},{"created":"2022-11-23T15:24:57.245808+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1033","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FBN1 as ready","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T15:24:57.186585+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1033","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fbn1 has been classified as Red List (Low Evidence).","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T15:24:53.523879+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1033","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FBN1 were changed from Marfan's syndrome; Weill-Marchesani syndrome 2, dominant; Shprintzen-Goldberg syndrome to Marfan syndrome, MIM# 154700","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T15:24:35.128582+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1032","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: FBN1 as Red List (low evidence)","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T15:24:35.116789+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1032","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fbn1 has been classified as Red List (Low Evidence).","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T15:24:25.904492+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1031","user_name":"Zornitza Stark","item_type":"entity","text":"Tag for review tag was added to gene: FBN1.","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T15:24:15.137699+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1031","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FBN1: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Marfan syndrome, MIM# 154700; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"FBN1","entity_type":"gene"},{"created":"2022-11-23T15:17:48.354530+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1031","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: GDAP1 as ready","entity_name":"GDAP1","entity_type":"gene"},{"created":"2022-11-23T15:17:48.320636+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1031","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: gdap1 has been classified as Red List (Low Evidence).","entity_name":"GDAP1","entity_type":"gene"},{"created":"2022-11-23T15:17:43.100389+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1031","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: GDAP1 were changed from Charcot-Marie-Tooth disease to Charcot-Marie-Tooth disease, axonal, type 2K, MIM#607831; Charcot-Marie-Tooth disease, axonal, with vocal cord paresis, MIM#607706; Charcot-Marie-Tooth disease, recessive intermediate, A, MIM#608340; Charcot-Marie-Tooth disease, type 4A, MIM#214400","entity_name":"GDAP1","entity_type":"gene"},{"created":"2022-11-23T15:17:28.095341+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1030","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: GDAP1 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal","entity_name":"GDAP1","entity_type":"gene"},{"created":"2022-11-23T15:17:19.158541+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1029","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: GDAP1 was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"GDAP1","entity_type":"gene"},{"created":"2022-11-23T15:17:08.478405+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1028","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: GDAP1 as Red List (low evidence)","entity_name":"GDAP1","entity_type":"gene"},{"created":"2022-11-23T15:17:08.465014+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1028","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: gdap1 has been classified as Red List (Low Evidence).","entity_name":"GDAP1","entity_type":"gene"},{"created":"2022-11-23T10:51:35.447206+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1027","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FERMT3 as ready","entity_name":"FERMT3","entity_type":"gene"},{"created":"2022-11-23T10:51:35.431022+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1027","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fermt3 has been classified as Green List (High Evidence).","entity_name":"FERMT3","entity_type":"gene"},{"created":"2022-11-23T10:50:34.109353+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1027","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: FERMT3.","entity_name":"FERMT3","entity_type":"gene"},{"created":"2022-11-23T10:50:20.157130+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1027","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FERMT3: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Leukocyte adhesion deficiency, type III, MIM# 612840; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FERMT3","entity_type":"gene"},{"created":"2022-11-23T10:46:39.742824+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1027","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FGA as ready","entity_name":"FGA","entity_type":"gene"},{"created":"2022-11-23T10:46:39.729019+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1027","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fga has been classified as Green List (High Evidence).","entity_name":"FGA","entity_type":"gene"},{"created":"2022-11-23T10:46:35.954700+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1027","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FGA were changed from Afibrinogenaemia to Afibrinogenemia, congenital (MIM#202400)","entity_name":"FGA","entity_type":"gene"},{"created":"2022-11-23T10:46:18.175419+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1026","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FGA: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Afibrinogenemia, congenital (MIM#202400); Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FGA","entity_type":"gene"},{"created":"2022-11-23T10:43:54.575853+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1026","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FGB as ready","entity_name":"FGB","entity_type":"gene"},{"created":"2022-11-23T10:43:54.552947+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1026","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: fgb has been classified as Green List (High Evidence).","entity_name":"FGB","entity_type":"gene"},{"created":"2022-11-23T10:43:51.120458+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1026","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: FGB were changed from Afibrinogenaemia to Afibrinogenaemia, congenital, MIM# 202400","entity_name":"FGB","entity_type":"gene"},{"created":"2022-11-23T10:43:36.061832+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1025","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: FGB: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Afibrinogenaemia, congenital, MIM# 202400; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"FGB","entity_type":"gene"},{"created":"2022-11-23T10:41:26.704010+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.1025","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: FGD1 as ready","entity_name":"FGD1","entity_type":"gene"}]}