{"count":221272,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=708","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=706","results":[{"created":"2022-10-27T18:22:35.704771+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.686","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COL13A1 as ready","entity_name":"COL13A1","entity_type":"gene"},{"created":"2022-10-27T18:22:35.695762+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.686","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: col13a1 has been classified as Green List (High Evidence).","entity_name":"COL13A1","entity_type":"gene"},{"created":"2022-10-27T18:22:27.952351+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.686","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: COL13A1.","entity_name":"COL13A1","entity_type":"gene"},{"created":"2022-10-27T18:22:19.799789+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.686","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COL13A1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Myasthenic syndrome, congenital, 19 (OMIM #616720); Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COL13A1","entity_type":"gene"},{"created":"2022-10-27T18:00:11.503867+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.686","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: COL11A2 as Green List (high evidence)","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T18:00:11.490056+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.686","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: col11a2 has been classified as Green List (High Evidence).","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:59:56.671006+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.685","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: COL11A2: Changed rating: GREEN","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:59:03.942076+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.685","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COL11A2 as ready","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:59:03.931865+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.685","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: col11a2 has been classified as Red List (Low Evidence).","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:57:20.440275+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.685","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: COL11A2 were changed from Otospondylomegaepiphyseal dysplasia to Deafness, autosomal recessive 53, MIM# 609706","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:55:37.540124+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.684","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: COL11A2 was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to BIALLELIC, autosomal or pseudoautosomal","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:55:27.513405+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.683","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: COL11A2 as Red List (low evidence)","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:55:27.496401+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.683","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: col11a2 has been classified as Red List (Low Evidence).","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:55:13.917319+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.682","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COL11A2: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Deafness, autosomal recessive 53, MIM# 609706; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COL11A2","entity_type":"gene"},{"created":"2022-10-27T17:51:11.684870+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.682","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COL11A1 as ready","entity_name":"COL11A1","entity_type":"gene"},{"created":"2022-10-27T17:51:11.673356+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.682","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: col11a1 has been classified as Green List (High Evidence).","entity_name":"COL11A1","entity_type":"gene"},{"created":"2022-10-27T17:51:08.138038+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.682","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: COL11A1 were changed from Stickler syndrome to Stickler syndrome, type II, MIM# 604841","entity_name":"COL11A1","entity_type":"gene"},{"created":"2022-10-27T17:50:53.864091+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.681","user_name":"Zornitza Stark","item_type":"entity","text":"Tag for review tag was added to gene: COL11A1.","entity_name":"COL11A1","entity_type":"gene"},{"created":"2022-10-27T17:50:43.393519+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.681","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COL11A1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Stickler syndrome, type II, MIM# 604841; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"COL11A1","entity_type":"gene"},{"created":"2022-10-27T17:44:32.417266+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.681","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: COG5 as ready","entity_name":"COG5","entity_type":"gene"},{"created":"2022-10-27T17:44:32.401040+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.681","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cog5 has been classified as Red List (Low Evidence).","entity_name":"COG5","entity_type":"gene"},{"created":"2022-10-27T17:44:24.157472+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.681","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: COG5 were changed from Congenital disorder of glycosylation, type IIi to Congenital disorder of glycosylation, type IIi, MIM# 613612","entity_name":"COG5","entity_type":"gene"},{"created":"2022-10-27T17:44:10.647181+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.680","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: COG5 as Red List (low evidence)","entity_name":"COG5","entity_type":"gene"},{"created":"2022-10-27T17:44:10.629981+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.680","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: cog5 has been classified as Red List (Low Evidence).","entity_name":"COG5","entity_type":"gene"},{"created":"2022-10-27T17:43:59.627147+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.679","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: COG5: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: Congenital disorder of glycosylation, type IIi, MIM# 613612; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"COG5","entity_type":"gene"},{"created":"2022-10-27T15:09:58.084485+11:00","panel_name":"Defects of innate immunity","panel_id":231,"panel_version":"0.126","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: TMC6: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 12426567, PMID 15042430; Phenotypes: Epidermodysplasia veruciformis; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMC6","entity_type":"gene"},{"created":"2022-10-27T15:08:56.808420+11:00","panel_name":"Defects of innate immunity","panel_id":231,"panel_version":"0.126","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: TLR3: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 17872438, PMID: 25339207; Phenotypes: Susceptibility to viral disease; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"TLR3","entity_type":"gene"},{"created":"2022-10-27T15:07:38.470875+11:00","panel_name":"Defects of innate immunity","panel_id":231,"panel_version":"0.126","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: TICAM1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 22105173, 26513235; Phenotypes: Herpes encephalitis; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"TICAM1","entity_type":"gene"},{"created":"2022-10-27T15:05:30.331921+11:00","panel_name":"Defects of innate immunity","panel_id":231,"panel_version":"0.126","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: TBK1: Rating: GREEN; Mode of pathogenicity: Other; Publications: PMID: 34363755, PMID: 22851595; Phenotypes: Autoinflammation, susceptibility to HSV; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"TBK1","entity_type":"gene"},{"created":"2022-10-27T15:00:10.658409+11:00","panel_name":"Defects of innate immunity","panel_id":231,"panel_version":"0.126","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: STAT2: Rating: GREEN; Mode of pathogenicity: Other; Publications: PMID: 34448086; Phenotypes: Susceptibility to viral disease, interferonopathy; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"STAT2","entity_type":"gene"},{"created":"2022-10-27T14:55:49.080435+11:00","panel_name":"Defects of innate immunity","panel_id":231,"panel_version":"0.126","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: STAT1: Rating: GREEN; Mode of pathogenicity: Other; Publications: PMID: 12590259, PMID: 16585605; Phenotypes: Immunodeficiency 31B, mycobacterial and viral infections, autosomal recessive, Immunodeficiency 31C, autosomal dominant, MIM# 614162, Predisposition to Mucocutaneous Candidiasis; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"STAT1","entity_type":"gene"},{"created":"2022-10-27T14:47:55.337132+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.106","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: TMC8: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 34459021, 28646613, 12426567; Phenotypes: Epidermodysplasia verruciformis 2; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMC8","entity_type":"gene"},{"created":"2022-10-27T14:46:11.182916+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.106","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: TMC6: Rating: ; Mode of pathogenicity: None; Publications: PMID: 12426567, PMID 15042430; Phenotypes: Epidermodysplasia veruciformis; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"TMC6","entity_type":"gene"},{"created":"2022-10-27T14:41:53.759711+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.106","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: CXCR4: Rating: GREEN; Mode of pathogenicity: None; Publications: 12692554; Phenotypes: WHIM syndrome; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"CXCR4","entity_type":"gene"},{"created":"2022-10-27T10:58:06.949247+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.106","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TLR3 as ready","entity_name":"TLR3","entity_type":"gene"},{"created":"2022-10-27T10:58:06.921289+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.106","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tlr3 has been classified as Green List (High Evidence).","entity_name":"TLR3","entity_type":"gene"},{"created":"2022-10-27T10:58:02.053199+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.106","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TLR3 were changed from  to {Immunodeficiency 83, susceptibility to viral infections}, MIM# 613002","entity_name":"TLR3","entity_type":"gene"},{"created":"2022-10-27T10:57:19.795541+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.105","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TLR3 were set to ","entity_name":"TLR3","entity_type":"gene"},{"created":"2022-10-27T10:56:48.801219+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.104","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TLR3 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"TLR3","entity_type":"gene"},{"created":"2022-10-27T10:54:28.438461+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.103","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TLR3: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: {Immunodeficiency 83, susceptibility to viral infections}, MIM# 613002; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"TLR3","entity_type":"gene"},{"created":"2022-10-27T10:47:24.543087+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.679","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: OXCT1 as ready","entity_name":"OXCT1","entity_type":"gene"},{"created":"2022-10-27T10:47:24.534364+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.679","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: oxct1 has been classified as Green List (High Evidence).","entity_name":"OXCT1","entity_type":"gene"},{"created":"2022-10-27T10:46:56.124311+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.679","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: OXCT1.","entity_name":"OXCT1","entity_type":"gene"},{"created":"2022-10-27T10:46:11.151158+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.679","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: OTOGL as ready","entity_name":"OTOGL","entity_type":"gene"},{"created":"2022-10-27T10:46:11.142725+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.679","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: otogl has been classified as Green List (High Evidence).","entity_name":"OTOGL","entity_type":"gene"},{"created":"2022-10-27T10:46:07.064559+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.679","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OTOGL were changed from Deafness, autosomal recessive to Deafness, autosomal recessive 84B, MIM# 614944","entity_name":"OTOGL","entity_type":"gene"},{"created":"2022-10-27T10:45:51.719616+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.678","user_name":"Zornitza Stark","item_type":"entity","text":"Tag for review tag was added to gene: OTOGL.","entity_name":"OTOGL","entity_type":"gene"},{"created":"2022-10-27T10:45:42.470317+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.678","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: OTOGL: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Deafness, autosomal recessive 84B, MIM# 614944; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"OTOGL","entity_type":"gene"},{"created":"2022-10-27T10:43:52.608967+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.678","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: OTOF as ready","entity_name":"OTOF","entity_type":"gene"},{"created":"2022-10-27T10:43:52.596521+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.678","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: otof has been classified as Green List (High Evidence).","entity_name":"OTOF","entity_type":"gene"},{"created":"2022-10-27T10:43:48.373569+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.678","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OTOF were changed from Deafness, autosomal recessive to Deafness, autosomal recessive 9, MIM#601071","entity_name":"OTOF","entity_type":"gene"},{"created":"2022-10-27T10:43:02.544747+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.677","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: OTOA as ready","entity_name":"OTOA","entity_type":"gene"},{"created":"2022-10-27T10:43:02.529481+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.677","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: otoa has been classified as Green List (High Evidence).","entity_name":"OTOA","entity_type":"gene"},{"created":"2022-10-27T10:42:59.570096+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.677","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OTOA were changed from Deafness, autosomal recessive to Deafness, autosomal recessive 22, MIM#607039","entity_name":"OTOA","entity_type":"gene"},{"created":"2022-10-27T10:42:44.022698+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.676","user_name":"Zornitza Stark","item_type":"entity","text":"Tag SV/CNV tag was added to gene: OTOA.","entity_name":"OTOA","entity_type":"gene"},{"created":"2022-10-27T10:42:03.102231+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.5007","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: OTC as ready","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:42:03.083923+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.5007","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: otc has been classified as Green List (High Evidence).","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:41:57.448423+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.5007","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OTC were changed from  to Ornithine transcarbamylase deficiency, MIM#311250","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:41:20.441667+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.5006","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: OTC was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:40:50.367491+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.5005","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: OTC: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Ornithine transcarbamylase deficiency, MIM#311250; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:39:34.272804+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"0.5005","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: OTC.","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:39:12.109337+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.424","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: OTC.","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:38:51.092495+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.676","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: OTC as ready","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:38:51.083908+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.676","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: otc has been classified as Green List (High Evidence).","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:38:39.752045+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.676","user_name":"Zornitza Stark","item_type":"entity","text":"Tag treatable tag was added to gene: OTC.","entity_name":"OTC","entity_type":"gene"},{"created":"2022-10-27T10:37:19.080028+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.676","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: OSTM1 as ready","entity_name":"OSTM1","entity_type":"gene"},{"created":"2022-10-27T10:37:19.071544+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.676","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ostm1 has been classified as Red List (Low Evidence).","entity_name":"OSTM1","entity_type":"gene"},{"created":"2022-10-27T10:37:15.811208+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.676","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OSTM1 were changed from Osteopetrosis to Osteopetrosis, autosomal recessive 5, MIM#259720","entity_name":"OSTM1","entity_type":"gene"},{"created":"2022-10-27T10:36:42.810149+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.675","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: OSTM1 were set to ","entity_name":"OSTM1","entity_type":"gene"},{"created":"2022-10-27T10:36:30.978456+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.674","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: OSTM1 as Red List (low evidence)","entity_name":"OSTM1","entity_type":"gene"},{"created":"2022-10-27T10:36:30.968514+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.674","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ostm1 has been classified as Red List (Low Evidence).","entity_name":"OSTM1","entity_type":"gene"},{"created":"2022-10-27T10:26:38.435589+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.103","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TICAM1 as ready","entity_name":"TICAM1","entity_type":"gene"},{"created":"2022-10-27T10:26:38.426537+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.103","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ticam1 has been classified as Green List (High Evidence).","entity_name":"TICAM1","entity_type":"gene"},{"created":"2022-10-27T09:30:23.566654+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.103","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TICAM1 were changed from  to {Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 6}, MIM# 614850","entity_name":"TICAM1","entity_type":"gene"},{"created":"2022-10-27T09:29:44.924746+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.102","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TICAM1 were set to ","entity_name":"TICAM1","entity_type":"gene"},{"created":"2022-10-27T09:29:08.170907+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.101","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: TICAM1: Added comment: Two each with bi-allelic and mono-allelic variants (total of 4 patients), plus functional data.; Changed publications: 22105173, 26513235","entity_name":"TICAM1","entity_type":"gene"},{"created":"2022-10-27T09:29:06.048274+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.101","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: STAT2: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 23391734, PMID: 34448086; Phenotypes: Susceptibility to viral disease; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"STAT2","entity_type":"gene"},{"created":"2022-10-27T09:28:14.362968+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.101","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TICAM1 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"TICAM1","entity_type":"gene"},{"created":"2022-10-27T09:27:47.619236+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.100","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: TICAM1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: {Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 6}, MIM# 614850; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"TICAM1","entity_type":"gene"},{"created":"2022-10-27T09:27:04.832299+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.100","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: STAT1 as ready","entity_name":"STAT1","entity_type":"gene"},{"created":"2022-10-27T09:27:04.814614+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.100","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: stat1 has been classified as Green List (High Evidence).","entity_name":"STAT1","entity_type":"gene"},{"created":"2022-10-27T09:27:01.470645+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.100","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: STAT1 were changed from  to Immunodeficiency 31B, mycobacterial and viral infections, autosomal recessive, MIM# 613796","entity_name":"STAT1","entity_type":"gene"},{"created":"2022-10-27T09:26:28.659639+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.99","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: STAT1 were set to ","entity_name":"STAT1","entity_type":"gene"},{"created":"2022-10-27T09:25:59.797098+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.98","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: STAT1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"STAT1","entity_type":"gene"},{"created":"2022-10-27T09:25:26.239242+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.97","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: STAT1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Immunodeficiency 31B, mycobacterial and viral infections, autosomal recessive, MIM# 613796; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal","entity_name":"STAT1","entity_type":"gene"},{"created":"2022-10-27T09:24:27.356075+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.673","user_name":"Zornitza Stark","item_type":"entity","text":"changed review comment from: Bi-allelic variants cause either multi-system CDG or congenital myasthenia graves.\r\n\r\nDifficult to predict phenotype from genotype but MG may be responsive to treatment.\r\n\r\nPhenotype may already be apparent in newborn period so clinical correlation possible.; to: Bi-allelic variants cause either multi-system CDG or congenital myasthenia gravis.\r\n\r\nDifficult to predict phenotype from genotype but MG may be responsive to treatment.\r\n\r\nPhenotype may already be apparent in newborn period so clinical correlation possible.","entity_name":"DPAGT1","entity_type":"gene"},{"created":"2022-10-27T09:22:30.520422+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.673","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: UMOD as ready","entity_name":"UMOD","entity_type":"gene"},{"created":"2022-10-27T09:22:30.512431+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.673","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: umod has been classified as Red List (Low Evidence).","entity_name":"UMOD","entity_type":"gene"},{"created":"2022-10-27T09:22:26.592048+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.673","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: UMOD were changed from Nephropathy to Tubulointerstitial kidney disease MIM#162000","entity_name":"UMOD","entity_type":"gene"},{"created":"2022-10-27T09:22:15.530839+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.672","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: UMOD were set to ","entity_name":"UMOD","entity_type":"gene"},{"created":"2022-10-27T09:22:03.182960+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.671","user_name":"Zornitza Stark","item_type":"entity","text":"Classified gene: UMOD as Red List (low evidence)","entity_name":"UMOD","entity_type":"gene"},{"created":"2022-10-27T09:22:03.151920+11:00","panel_name":"gNBS","panel_id":3931,"panel_version":"0.671","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: umod has been classified as Red List (Low Evidence).","entity_name":"UMOD","entity_type":"gene"},{"created":"2022-10-27T09:20:38.711337+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.97","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TBK1 as ready","entity_name":"TBK1","entity_type":"gene"},{"created":"2022-10-27T09:20:38.703011+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.97","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: tbk1 has been classified as Green List (High Evidence).","entity_name":"TBK1","entity_type":"gene"},{"created":"2022-10-27T09:20:28.711259+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.97","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TBK1 were changed from  to Hereditary predisposition to infections, MONDO:0015979, TBK1-related","entity_name":"TBK1","entity_type":"gene"},{"created":"2022-10-27T09:20:02.143585+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.96","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: TBK1 were set to ","entity_name":"TBK1","entity_type":"gene"},{"created":"2022-10-27T09:18:30.788406+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.95","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of pathogenicity for gene: TBK1 was changed from Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments to Other","entity_name":"TBK1","entity_type":"gene"},{"created":"2022-10-27T09:18:13.377523+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.95","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of pathogenicity for gene: TBK1 was changed from  to Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments","entity_name":"TBK1","entity_type":"gene"},{"created":"2022-10-27T09:17:46.693007+11:00","panel_name":"Susceptibility to Viral Infections","panel_id":237,"panel_version":"0.94","user_name":"Peter McNaughton","item_type":"entity","text":"reviewed gene: TLR3: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 17872438, PMID: 25339207; Phenotypes: Herpes encephalitis; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","entity_name":"TLR3","entity_type":"gene"},{"created":"2022-10-27T07:13:36.875862+11:00","panel_name":"Retinitis pigmentosa_Autosomal Recessive/X-linked","panel_id":277,"panel_version":"0.130","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: RAX2 as ready","entity_name":"RAX2","entity_type":"gene"}]}