{"count":220497,"next":"https://panelapp-aus.org/api/v1/activities/?format=json&page=98","previous":"https://panelapp-aus.org/api/v1/activities/?format=json&page=96","results":[{"created":"2025-12-07T17:51:36.722112+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1252","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pdhx has been classified as Green List (High Evidence).","entity_name":"PDHX","entity_type":"gene"},{"created":"2025-12-07T17:51:32.848893+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1252","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PDHX were changed from Lacticacidaemia due to PDX1 deficiency MIM#245349 to Lactic acidaemia due to PDX1 deficiency MIM#245349","entity_name":"PDHX","entity_type":"gene"},{"created":"2025-12-07T17:50:59.993399+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1251","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PDHX were changed from  to Lacticacidaemia due to PDX1 deficiency MIM#245349","entity_name":"PDHX","entity_type":"gene"},{"created":"2025-12-07T17:50:26.333846+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1250","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: PDHX were set to ","entity_name":"PDHX","entity_type":"gene"},{"created":"2025-12-07T17:49:55.529482+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1249","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PDHX was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PDHX","entity_type":"gene"},{"created":"2025-12-07T17:49:15.268502+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1248","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: PDHB as ready","entity_name":"PDHB","entity_type":"gene"},{"created":"2025-12-07T17:49:15.261513+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1248","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: pdhb has been classified as Green List (High Evidence).","entity_name":"PDHB","entity_type":"gene"},{"created":"2025-12-07T17:49:11.975796+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1248","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: PDHB were changed from  to Pyruvate dehydrogenase E1-beta deficiency - MIM#614111","entity_name":"PDHB","entity_type":"gene"},{"created":"2025-12-07T17:48:37.415449+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1247","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: PDHB was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"PDHB","entity_type":"gene"},{"created":"2025-12-07T17:45:12.405385+11:00","panel_name":"Ataxia","panel_id":271,"panel_version":"1.155","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OPA1 were changed from Behr syndrome, 210000; Optic atrophy plus syndrome, 125250; Optic atrophy 1, 165500 to OPA1-related optic atrophy with or without extraocular features, MONDO:0800181","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:44:03.165727+11:00","panel_name":"Deafness_IsolatedAndComplex","panel_id":209,"panel_version":"1.302","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OPA1 were changed from Optic atrophy plus syndrome, MIM# 125250 to OPA1-related optic atrophy with or without extraocular features, MONDO:0800181","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:43:37.025046+11:00","panel_name":"Deafness_IsolatedAndComplex","panel_id":209,"panel_version":"1.301","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: OPA1: Changed phenotypes: OPA1-related optic atrophy with or without extraocular features, MONDO:0800181","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:43:19.433991+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"1.61","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OPA1 were changed from Optic atrophy 1 165500; Optic atrophy plus syndrome, MIM# 125250; Behr syndrome, MIM# 210000 to OPA1-related optic atrophy with or without extraocular features, MONDO:0800181","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:42:26.651221+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.3744","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OPA1 were changed from Mitochondrial DNA depletion syndrome 14 (encephalocardiomyopathic type)MIM# 616896; Behr syndrome MIM#210000, AR; Optic atrophy 1, MIM#165500; Optic atrophy plus syndrome, MIM# 125250 to OPA1-related optic atrophy with or without extraocular features, MONDO:0800181","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:41:42.697137+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.3743","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: OPA1 were set to 30165240","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:41:39.744716+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.3743","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: OPA1 were set to ","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:41:39.688230+11:00","panel_name":"Optic Atrophy","panel_id":149,"panel_version":"1.60","user_name":"Zornitza Stark","item_type":"panel","text":"Added reviews for gene OPA1 from panel Mitochondrial disease","entity_name":null,"entity_type":null},{"created":"2025-12-07T17:40:59.454437+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.3743","user_name":"Zornitza Stark","item_type":"panel","text":"Added reviews for gene OPA1 from panel Mitochondrial disease","entity_name":null,"entity_type":null},{"created":"2025-12-07T17:40:46.563664+11:00","panel_name":"Deafness_IsolatedAndComplex","panel_id":209,"panel_version":"1.301","user_name":"Zornitza Stark","item_type":"panel","text":"Added reviews for gene OPA1 from panel Mitochondrial disease","entity_name":null,"entity_type":null},{"created":"2025-12-07T17:40:11.181294+11:00","panel_name":"Ataxia","panel_id":271,"panel_version":"1.154","user_name":"Zornitza Stark","item_type":"panel","text":"Added reviews for gene OPA1 from panel Mitochondrial disease","entity_name":null,"entity_type":null},{"created":"2025-12-07T17:38:29.873399+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1246","user_name":"Zornitza Stark","item_type":"entity","text":"reviewed gene: OPA1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: OPA1-related optic atrophy with or without extraocular features, MONDO:0800181; Mode of inheritance: BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:36:04.709886+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1246","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: OPA1 as ready","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:36:04.694141+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1246","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: opa1 has been classified as Green List (High Evidence).","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:35:58.813179+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1246","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: OPA1 were changed from  to OPA1-related optic atrophy with or without extraocular features, MONDO:0800181","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:34:37.653368+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1245","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: OPA1 were set to ","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:34:02.936388+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1244","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: OPA1 was changed from Unknown to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal","entity_name":"OPA1","entity_type":"gene"},{"created":"2025-12-07T17:33:13.403764+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1243","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDUFV1 as ready","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2025-12-07T17:33:13.394081+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1243","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ndufv1 has been classified as Green List (High Evidence).","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2025-12-07T17:30:32.177881+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1243","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFV1 were changed from  to Mitochondrial complex I deficiency, nuclear type 4 MIM#618225","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2025-12-07T17:30:04.777407+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1242","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDUFV1 were set to ","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2025-12-07T17:29:36.558109+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1241","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDUFV1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NDUFV1","entity_type":"gene"},{"created":"2025-12-07T17:28:59.584238+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1240","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDUFS8 as ready","entity_name":"NDUFS8","entity_type":"gene"},{"created":"2025-12-07T17:28:59.573554+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1240","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ndufs8 has been classified as Green List (High Evidence).","entity_name":"NDUFS8","entity_type":"gene"},{"created":"2025-12-07T17:28:56.886504+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1240","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFS8 were changed from  to Mitochondrial complex I deficiency, nuclear type 2 MIM#618222","entity_name":"NDUFS8","entity_type":"gene"},{"created":"2025-12-07T17:28:15.894607+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1239","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDUFS8 were set to ","entity_name":"NDUFS8","entity_type":"gene"},{"created":"2025-12-07T17:27:39.752606+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1238","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDUFS8 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NDUFS8","entity_type":"gene"},{"created":"2025-12-07T17:27:03.993108+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1237","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDUFS7 as ready","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2025-12-07T17:27:03.978875+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1237","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ndufs7 has been classified as Green List (High Evidence).","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2025-12-07T17:27:01.037568+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1237","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFS7 were changed from  to Mitochondrial complex I deficiency, nuclear type 3 (MIM# 618224)","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2025-12-07T17:26:25.098162+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1236","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDUFS7 were set to ","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2025-12-07T17:25:51.218677+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1235","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDUFS7 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NDUFS7","entity_type":"gene"},{"created":"2025-12-07T17:25:08.522827+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1234","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDUFAF5 as ready","entity_name":"NDUFAF5","entity_type":"gene"},{"created":"2025-12-07T17:25:08.512384+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1234","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ndufaf5 has been classified as Green List (High Evidence).","entity_name":"NDUFAF5","entity_type":"gene"},{"created":"2025-12-07T17:25:05.657477+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1234","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFAF5 were changed from  to Mitochondrial complex I deficiency, nuclear type 3 MIM#618224","entity_name":"NDUFAF5","entity_type":"gene"},{"created":"2025-12-07T17:24:32.209970+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1233","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDUFAF5 were set to ","entity_name":"NDUFAF5","entity_type":"gene"},{"created":"2025-12-07T17:24:01.004309+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1232","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDUFAF5 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"NDUFAF5","entity_type":"gene"},{"created":"2025-12-07T17:23:15.222710+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1231","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: NDUFA1 as ready","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2025-12-07T17:23:15.212708+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1231","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: ndufa1 has been classified as Green List (High Evidence).","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2025-12-07T17:23:12.620148+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1231","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: NDUFA1 were changed from  to Mitochondrial complex I deficiency, nuclear type 12 MIM#301020","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2025-12-07T17:22:35.880061+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1230","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: NDUFA1 were set to ","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2025-12-07T17:22:01.336297+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1229","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: NDUFA1 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"NDUFA1","entity_type":"gene"},{"created":"2025-12-07T17:20:59.768313+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1228","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: MPV17 as ready","entity_name":"MPV17","entity_type":"gene"},{"created":"2025-12-07T17:20:59.760731+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1228","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: mpv17 has been classified as Green List (High Evidence).","entity_name":"MPV17","entity_type":"gene"},{"created":"2025-12-07T17:20:42.871555+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1228","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: MPV17 were changed from  to Charcot-Marie-Tooth disease, axonal, type 2EE, MIM# 618400","entity_name":"MPV17","entity_type":"gene"},{"created":"2025-12-07T17:20:08.910109+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1227","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: MPV17 were set to ","entity_name":"MPV17","entity_type":"gene"},{"created":"2025-12-07T17:19:35.215508+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1226","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: MPV17 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"MPV17","entity_type":"gene"},{"created":"2025-12-07T17:18:54.573266+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1225","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: MFN2 as ready","entity_name":"MFN2","entity_type":"gene"},{"created":"2025-12-07T17:18:54.562621+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1225","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: mfn2 has been classified as Green List (High Evidence).","entity_name":"MFN2","entity_type":"gene"},{"created":"2025-12-07T17:18:44.628464+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1225","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: MFN2 were changed from  to Charcot-Marie-Tooth disease, axonal, type 2A2A 609260; Charcot-Marie-Tooth disease, axonal, type 2A2B, MIM# 617087; Hereditary motor and sensory neuropathy VIA, MIM# 601152","entity_name":"MFN2","entity_type":"gene"},{"created":"2025-12-07T17:17:55.856361+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1224","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: MFN2 were set to ","entity_name":"MFN2","entity_type":"gene"},{"created":"2025-12-07T17:17:06.537343+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1223","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: MFN2 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal","entity_name":"MFN2","entity_type":"gene"},{"created":"2025-12-07T17:15:08.021551+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1222","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: TAZ as ready","entity_name":"TAZ","entity_type":"gene"},{"created":"2025-12-07T17:15:08.011673+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1222","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: taz has been classified as Green List (High Evidence).","entity_name":"TAZ","entity_type":"gene"},{"created":"2025-12-07T17:15:04.458286+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1222","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: TAZ were changed from  to Barth syndrome, MIM# 302060","entity_name":"TAZ","entity_type":"gene"},{"created":"2025-12-07T17:09:54.631656+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1221","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: TAZ was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females","entity_name":"TAZ","entity_type":"gene"},{"created":"2025-12-07T17:09:02.801432+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1220","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: MFF as ready","entity_name":"MFF","entity_type":"gene"},{"created":"2025-12-07T17:09:02.791324+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1220","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: mff has been classified as Green List (High Evidence).","entity_name":"MFF","entity_type":"gene"},{"created":"2025-12-07T17:08:59.185891+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1220","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: MFF were changed from  to Encephalopathy due to defective mitochondrial and peroxisomal fission 2, MIM# 617086","entity_name":"MFF","entity_type":"gene"},{"created":"2025-12-07T17:08:26.438386+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1219","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: MFF were set to ","entity_name":"MFF","entity_type":"gene"},{"created":"2025-12-07T16:47:05.081786+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1218","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: MFF was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"MFF","entity_type":"gene"},{"created":"2025-12-07T16:38:10.927878+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1217","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: MDH2 as ready","entity_name":"MDH2","entity_type":"gene"},{"created":"2025-12-07T16:38:10.920906+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1217","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: mdh2 has been classified as Green List (High Evidence).","entity_name":"MDH2","entity_type":"gene"},{"created":"2025-12-07T16:37:01.995952+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1217","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: MDH2 were changed from  to Developmental and epileptic encephalopathy 51 MIM#617339","entity_name":"MDH2","entity_type":"gene"},{"created":"2025-12-07T16:36:12.921406+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1216","user_name":"Zornitza Stark","item_type":"entity","text":"Publications for gene: MDH2 were set to ","entity_name":"MDH2","entity_type":"gene"},{"created":"2025-12-07T16:35:43.746750+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1215","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: MDH2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"MDH2","entity_type":"gene"},{"created":"2025-12-07T16:35:08.219886+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1214","user_name":"Zornitza Stark","item_type":"entity","text":"Marked gene: LYRM7 as ready","entity_name":"LYRM7","entity_type":"gene"},{"created":"2025-12-07T16:35:08.212603+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1214","user_name":"Zornitza Stark","item_type":"entity","text":"Gene: lyrm7 has been classified as Green List (High Evidence).","entity_name":"LYRM7","entity_type":"gene"},{"created":"2025-12-07T16:35:05.487231+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1214","user_name":"Zornitza Stark","item_type":"entity","text":"Phenotypes for gene: LYRM7 were changed from  to Mitochondrial complex III deficiency, nuclear type 8 - MIM#615838","entity_name":"LYRM7","entity_type":"gene"},{"created":"2025-12-07T16:34:29.408573+11:00","panel_name":"Mitochondrial disease","panel_id":203,"panel_version":"0.1213","user_name":"Zornitza Stark","item_type":"entity","text":"Mode of inheritance for gene: LYRM7 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal","entity_name":"LYRM7","entity_type":"gene"},{"created":"2025-12-07T13:11:37.555682+11:00","panel_name":"Mendeliome","panel_id":137,"panel_version":"1.3742","user_name":"Zornitza Stark","item_type":"panel","text":"Added reviews for gene PPM1K from panel Aminoacidopathy","entity_name":null,"entity_type":null},{"created":"2025-12-07T13:11:24.083027+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"1.487","user_name":"Zornitza Stark","item_type":"panel","text":"Added reviews for gene PPM1K from panel Aminoacidopathy","entity_name":null,"entity_type":null},{"created":"2025-12-07T13:09:56.012319+11:00","panel_name":"Aminoacidopathy","panel_id":3929,"panel_version":"1.138","user_name":"Zornitza Stark","item_type":"entity","text":"edited their review of gene: PPM1K: Added comment: Additional individual reported in PMID 40047138 noted. However, variant is homozygous missense and thus a VOUS.; Changed rating: AMBER; Changed publications: 23086801, 40047138","entity_name":"PPM1K","entity_type":"gene"},{"created":"2025-12-07T13:06:02.662019+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"1.486","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37390-Loss as ready","entity_name":"ISCA-37390-Loss","entity_type":"region"},{"created":"2025-12-07T13:06:02.655449+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"1.486","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37390-loss has been classified as Green List (High Evidence).","entity_name":"ISCA-37390-Loss","entity_type":"region"},{"created":"2025-12-07T13:05:45.973028+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"1.374","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37390-Loss as ready","entity_name":"ISCA-37390-Loss","entity_type":"region"},{"created":"2025-12-07T13:05:45.965783+11:00","panel_name":"Microcephaly","panel_id":138,"panel_version":"1.374","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37390-loss has been classified as Green List (High Evidence).","entity_name":"ISCA-37390-Loss","entity_type":"region"},{"created":"2025-12-07T13:05:28.741562+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"1.486","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37392-Gain as ready","entity_name":"ISCA-37392-Gain","entity_type":"region"},{"created":"2025-12-07T13:05:28.732475+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"1.486","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37392-gain has been classified as Green List (High Evidence).","entity_name":"ISCA-37392-Gain","entity_type":"region"},{"created":"2025-12-07T13:05:11.329244+11:00","panel_name":"Congenital Heart Defect","panel_id":76,"panel_version":"0.509","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37392-Loss as ready","entity_name":"ISCA-37392-Loss","entity_type":"region"},{"created":"2025-12-07T13:05:11.320141+11:00","panel_name":"Congenital Heart Defect","panel_id":76,"panel_version":"0.509","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37392-loss has been classified as Green List (High Evidence).","entity_name":"ISCA-37392-Loss","entity_type":"region"},{"created":"2025-12-07T13:04:56.942441+11:00","panel_name":"Growth failure","panel_id":3631,"panel_version":"1.86","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37392-Loss as ready","entity_name":"ISCA-37392-Loss","entity_type":"region"},{"created":"2025-12-07T13:04:56.936072+11:00","panel_name":"Growth failure","panel_id":3631,"panel_version":"1.86","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37392-loss has been classified as Green List (High Evidence).","entity_name":"ISCA-37392-Loss","entity_type":"region"},{"created":"2025-12-07T13:04:35.291518+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"1.486","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37392-Loss as ready","entity_name":"ISCA-37392-Loss","entity_type":"region"},{"created":"2025-12-07T13:04:35.283932+11:00","panel_name":"Intellectual disability syndromic and non-syndromic","panel_id":250,"panel_version":"1.486","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37392-loss has been classified as Green List (High Evidence).","entity_name":"ISCA-37392-Loss","entity_type":"region"},{"created":"2025-12-07T13:04:17.402889+11:00","panel_name":"Anophthalmia_Microphthalmia_Coloboma","panel_id":42,"panel_version":"1.53","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37393-Gain as ready","entity_name":"ISCA-37393-Gain","entity_type":"region"},{"created":"2025-12-07T13:04:17.382241+11:00","panel_name":"Anophthalmia_Microphthalmia_Coloboma","panel_id":42,"panel_version":"1.53","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37393-gain has been classified as Green List (High Evidence).","entity_name":"ISCA-37393-Gain","entity_type":"region"},{"created":"2025-12-07T13:03:59.211851+11:00","panel_name":"Clefting disorders","panel_id":3368,"panel_version":"0.293","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37393-Gain as ready","entity_name":"ISCA-37393-Gain","entity_type":"region"},{"created":"2025-12-07T13:03:59.201349+11:00","panel_name":"Clefting disorders","panel_id":3368,"panel_version":"0.293","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37393-gain has been classified as Green List (High Evidence).","entity_name":"ISCA-37393-Gain","entity_type":"region"},{"created":"2025-12-07T13:03:40.383954+11:00","panel_name":"Congenital Heart Defect","panel_id":76,"panel_version":"0.509","user_name":"Zornitza Stark","item_type":"entity","text":"Marked Region: ISCA-37393-Gain as ready","entity_name":"ISCA-37393-Gain","entity_type":"region"},{"created":"2025-12-07T13:03:40.375644+11:00","panel_name":"Congenital Heart Defect","panel_id":76,"panel_version":"0.509","user_name":"Zornitza Stark","item_type":"entity","text":"Region: isca-37393-gain has been classified as Green List (High Evidence).","entity_name":"ISCA-37393-Gain","entity_type":"region"}]}