Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
SCN5A	gene	SCN5A	Expert Review Green;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Atrial fibrillation, familial, 10;Brugada syndrome 1;Cardiomyopathy, dilated, 1E;Heart block, nonprogressive;Heart block, progressive, type IA;Long QT syndrome 3;Sick sinus syndrome 1;Ventricular fibrillation, familial, 1;{Sudden infant death syndrome, susceptibility to}				29806494;18929244		False	3	100;0;0	0.46	True	Other	ENSG00000183873	ENSG00000183873	HGNC:10593													
ABCC9	gene	ABCC9	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000069431	ENSG00000069431	HGNC:60													
ANK2	gene	ANK2	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000145362	ENSG00000145362	HGNC:493													
CACNA1C	gene	CACNA1C	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	Unknown					29959160		False	1	0;0;100	0.46	True		ENSG00000151067	ENSG00000151067	HGNC:1390													
CACNA2D1	gene	CACNA2D1	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	Unknown	Brugada syndrome 1, MONDO:0011001				29959160		False	1	0;0;100	0.46	True		ENSG00000153956	ENSG00000153956	HGNC:1399													
CACNB2	gene	CACNB2	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	Unknown					29959160		False	1	0;0;100	0.46	True		ENSG00000165995	ENSG00000165995	HGNC:1402													
FGF12	gene	FGF12	ClinGen	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome MONDO:0015263						False	1	0;0;100	0.46	False		ENSG00000114279	ENSG00000114279	HGNC:3668													
GPD1L	gene	GPD1L	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome 2, MIM# 611777				17967977;19666841;29959160		False	1	0;50;50	0.46	True		ENSG00000152642	ENSG00000152642	HGNC:28956													
HCN4	gene	HCN4	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000138622	ENSG00000138622	HGNC:16882													
KCND3	gene	KCND3	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	Unknown	Brugada syndrome				29959160		False	1	0;0;100	0.46	True		ENSG00000171385	ENSG00000171385	HGNC:6239													
KCNE3	gene	KCNE3	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	Unknown	Brugada syndrome, MONDO:0015263				29959160		False	1	0;0;100	0.46	True		ENSG00000175538	ENSG00000175538	HGNC:6243													
KCNE5	gene	KCNE5	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000176076	ENSG00000176076	HGNC:6241													
KCNH2	gene	KCNH2	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000055118	ENSG00000055118	HGNC:6251													
KCNJ8	gene	KCNJ8	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	Unknown	Brugada syndrome 1, MONDO:0011001				29959160		False	1	0;0;100	0.46	True		ENSG00000121361	ENSG00000121361	HGNC:6269													
PKP2	gene	PKP2	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000057294	ENSG00000057294	HGNC:9024													
RANGRF	gene	RANGRF	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000108961	ENSG00000108961	HGNC:17679													
SCN10A	gene	SCN10A	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	Unknown	Brugada syndrome				29959160		False	1	0;0;100	0.46	True		ENSG00000185313	ENSG00000185313	HGNC:10582													
SCN1B	gene	SCN1B	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	Unknown	Brugada syndrome 1, MONDO:0011001				29959160		False	1	0;0;100	0.46	True		ENSG00000105711	ENSG00000105711	HGNC:10586													
SCN2B	gene	SCN2B	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000149575	ENSG00000149575	HGNC:10589													
SCN3B	gene	SCN3B	Expert Review Red;Victorian Clinical Genetics Services	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome 7 MIM#613120						False	1	0;0;100	0.46	True		ENSG00000166257	ENSG00000166257	HGNC:20665													
SLMAP	gene	SLMAP	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000163681	ENSG00000163681	HGNC:16643													
TMEM168	gene	TMEM168	ClinGen	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome MONDO:0015263				https://search.clinicalgenome.org/CCID:009114		False	1	0;0;100	0.46	False		ENSG00000146802	ENSG00000146802	HGNC:25826													
TRPM4	gene	TRPM4	ClinGen;Expert Review Red	Brugada syndrome		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	0.46	True		ENSG00000130529	ENSG00000130529	HGNC:17993