Pulmonary Fibrosis_Interstitial Lung Disease

Gene: FGF10

Green List (high evidence)

FGF10 (fibroblast growth factor 10)
EnsemblGeneIds (GRCh38): ENSG00000070193
EnsemblGeneIds (GRCh37): ENSG00000070193
OMIM: 602115, Gene2Phenotype
FGF10 is in 9 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

Association with pulmonary hypoplasia and interstitial lung disease reported in multiple families.
Sources: Expert list
Created: 1 Aug 2025, 6:33 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Lacrimoauriculodentodigital (LAAD) syndrome - pulmonary hypoplasia

Publications

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Lacrimoauriculodentodigital (LAAD) syndrome - pulmonary hypoplasia
OMIM
602115
Clinvar variants
Variants in FGF10
Penetrance
None
Publications
Panels with this gene

History Filter Activity

1 Aug 2025, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: fgf10 has been classified as Green List (High Evidence).

1 Aug 2025, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: fgf10 has been classified as Green List (High Evidence).

1 Aug 2025, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: FGF10 was added gene: FGF10 was added to Pulmonary Fibrosis_Interstitial Lung Disease. Sources: Expert list Mode of inheritance for gene: FGF10 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: FGF10 were set to 30639323; 30429870; 9916808 Phenotypes for gene: FGF10 were set to Lacrimoauriculodentodigital (LAAD) syndrome - pulmonary hypoplasia Review for gene: FGF10 was set to GREEN