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Ataxia v2.17 ABCA2 Sangavi Sivagnanasundram Classified gene: ABCA2 as Green List (high evidence)
Ataxia v2.17 ABCA2 Sangavi Sivagnanasundram Gene: abca2 has been classified as Green List (High Evidence).
Ataxia v2.16 ABCA2 Sangavi Sivagnanasundram Classified gene: ABCA2 as Green List (high evidence)
Ataxia v2.16 ABCA2 Sangavi Sivagnanasundram Gene: abca2 has been classified as Green List (High Evidence).
Ataxia v2.15 ABCA2 Sangavi Sivagnanasundram gene: ABCA2 was added
gene: ABCA2 was added to Ataxia. Sources: Literature
Mode of inheritance for gene: ABCA2 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: ABCA2 were set to 38228874
Phenotypes for gene: ABCA2 were set to intellectual developmental disorder with poor growth and with or without seizures or ataxia, MONDO:0032930
Review for gene: ABCA2 was set to GREEN
Added comment: Biallelic ABCA2 variants present with a neurological disorder characterised by global developmental delay apparent from infancy, hypotonia, and poor overall growth, sometimes with borderline microcephaly.
3 unrelated individuals reported with ataxia as a presenting feature.
Sources: Literature