| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Mendeliome v1.4851 | ADGB | Zornitza Stark Marked gene: ADGB as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v1.4851 | ADGB | Zornitza Stark Gene: adgb has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v1.4851 | ADGB | Zornitza Stark Classified gene: ADGB as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v1.4851 | ADGB | Zornitza Stark Gene: adgb has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v1.4847 | ADGB |
Rylee Peters gene: ADGB was added gene: ADGB was added to Mendeliome. Sources: Literature Mode of inheritance for gene: ADGB was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: ADGB were set to 38385883; 36995441 Phenotypes for gene: ADGB were set to Infertility disorder, MONDO:0005047, ADGB-related Review for gene: ADGB was set to GREEN Added comment: PMID: 36995441 and PMID: 38385883 report four unrelated individuals with biallelic ADGB variants causing severe asthenoteratozoospermia. Functional studies including loss of ADGB protein in patient sperm and Adgb-/- male mice were infertile with immobile sperm. Sources: Literature |
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