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Mendeliome v1.4386 AKAP3 Bryony Thompson Classified gene: AKAP3 as Amber List (moderate evidence)
Mendeliome v1.4386 AKAP3 Bryony Thompson Gene: akap3 has been classified as Amber List (Moderate Evidence).
Mendeliome v1.4385 AKAP3 Bryony Thompson gene: AKAP3 was added
gene: AKAP3 was added to Mendeliome. Sources: Literature
Mode of inheritance for gene: AKAP3 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: AKAP3 were set to 35228300; 31969357
Phenotypes for gene: AKAP3 were set to spermatogenic failure MONDO:0004983
Review for gene: AKAP3 was set to AMBER
Added comment: 2 unrelated males from consanguineous families with homozygous variants (frameshift, missense), and supporting mouse model.
Sources: Literature