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Mendeliome v1.4401 NANOS1 Bryony Thompson Classified gene: NANOS1 as Amber List (moderate evidence)
Mendeliome v1.4401 NANOS1 Bryony Thompson Gene: nanos1 has been classified as Amber List (Moderate Evidence).
Mendeliome v1.4400 NANOS1 Bryony Thompson gene: NANOS1 was added
gene: NANOS1 was added to Mendeliome. Sources: Literature
Mode of inheritance for gene: NANOS1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for gene: NANOS1 were set to 23315541
Phenotypes for gene: NANOS1 were set to spermatogenic failure MONDO:0004983
Review for gene: NANOS1 was set to AMBER
Added comment: 5 men with 3 different non-synonymous variants and incomplete segregation. 2 of the variants are inframe deletions in repeat regions.
Sources: Literature
Mendeliome v0.9625 ANOS1 Zornitza Stark Marked gene: ANOS1 as ready
Mendeliome v0.9625 ANOS1 Zornitza Stark Gene: anos1 has been classified as Green List (High Evidence).
Mendeliome v0.9625 ANOS1 Zornitza Stark Phenotypes for gene: ANOS1 were changed from to Hypogonadotropic hypogonadism 1 with or without anosmia (Kallmann syndrome 1), MIM# 308700
Mendeliome v0.9624 ANOS1 Zornitza Stark Publications for gene: ANOS1 were set to
Mendeliome v0.9623 ANOS1 Zornitza Stark Mode of inheritance for gene: ANOS1 was changed from Unknown to X-LINKED: hemizygous mutation in males, biallelic mutations in females
Mendeliome v0.9622 ANOS1 Zornitza Stark reviewed gene: ANOS1: Rating: GREEN; Mode of pathogenicity: None; Publications: 1594017, 8504298, 8989261; Phenotypes: Hypogonadotropic hypogonadism 1 with or without anosmia (Kallmann syndrome 1), MIM# 308700; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females
Mendeliome v0.0 ANOS1 Zornitza Stark gene: ANOS1 was added
gene: ANOS1 was added to Mendeliome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services
Mode of inheritance for gene: ANOS1 was set to Unknown