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| Mendeliome v2.194 | ARR3 | Zornitza Stark Publications for gene: ARR3 were set to 27829781; 35001458 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v2.193 | ARR3 | Zornitza Stark Mode of inheritance for gene: ARR3 was changed from Other to X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v2.192 | ARR3 | Zornitza Stark reviewed gene: ARR3: Rating: GREEN; Mode of pathogenicity: None; Publications: 35001458, 37795829, 36964802, 37268727, 32215939, 36180177, 38789272, 42326764, 38517428, 38958970, 41631463, 39420435, 39495751, 34966409, 36769483; Phenotypes: Myopia 26, X-linked, female-limited MIM#301010; Mode of inheritance: X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v2.0 | ARR3 | Gene migrated from ENSG00000120500 to ENSG00000120500 (gene set migration) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v0.10908 | ARR3 | Bryony Thompson Marked gene: ARR3 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v0.10908 | ARR3 | Bryony Thompson Gene: arr3 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v0.10908 | ARR3 | Bryony Thompson Classified gene: ARR3 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v0.10908 | ARR3 | Bryony Thompson Gene: arr3 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mendeliome v0.10907 | ARR3 |
Bryony Thompson gene: ARR3 was added gene: ARR3 was added to Mendeliome. Sources: Literature Mode of inheritance for gene: ARR3 was set to Other Publications for gene: ARR3 were set to 27829781; 35001458 Phenotypes for gene: ARR3 were set to Myopia 26, X-linked, female-limited MIM#301010 Review for gene: ARR3 was set to GREEN Added comment: At least 6 multi-generational families with female-limited early-onset high myopia. Only female carriers are affected and hemizygous males are unaffected. Authors hypothesise the mode of inheritance might be explained by metabolic interference due to X-inactivation. Sources: Literature |
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