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Mendeliome v2.213 ATG9A chirag patel Mode of inheritance for gene: ATG9A was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Mendeliome v2.212 ATG9A chirag patel Publications for gene: ATG9A were set to 35838483
Mendeliome v2.212 ATG9A chirag patel Phenotypes for gene: ATG9A were changed from Autophagy-associated immune dysregulation and hyperplasia; Young-onset Parkinson disease, MONDO:0017279 to Autophagy-associated immune dysregulation and hyperplasia; Young-onset Parkinson disease, MONDO:0017279
Mendeliome v2.211 ATG9A chirag patel Phenotypes for gene: ATG9A were changed from Autophagy-associated immune dysregulation and hyperplasia to Autophagy-associated immune dysregulation and hyperplasia; Young-onset Parkinson disease, MONDO:0017279
Mendeliome v2.210 ATG9A chirag patel reviewed gene: ATG9A: Rating: RED; Mode of pathogenicity: None; Publications: 42327715; Phenotypes: Young-onset Parkinson disease, MONDO:0017279; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Mendeliome v2.0 ATG9A Gene migrated from ENSG00000198925 to ENSG00000198925 (gene set migration)
Mendeliome v1.2119 ATG9A Bryony Thompson Marked gene: ATG9A as ready
Mendeliome v1.2119 ATG9A Bryony Thompson Gene: atg9a has been classified as Red List (Low Evidence).
Mendeliome v1.2119 ATG9A Bryony Thompson gene: ATG9A was added
gene: ATG9A was added to Mendeliome. Sources: Literature
Mode of inheritance for gene: ATG9A was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: ATG9A were set to 35838483
Phenotypes for gene: ATG9A were set to Autophagy-associated immune dysregulation and hyperplasia
Review for gene: ATG9A was set to RED
Added comment: A single case with compound heterozygous variants was reported. After infection with Epstein-Barr virus (EBV), the patient developed hyperplastic proliferation of T and B cells in the lung and brain and exhibited defects in lymphocyte memory cell populations. In vitro functional assays.
Sources: Literature