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Mendeliome v1.1945 CLDN2 Zornitza Stark Classified gene: CLDN2 as Red List (low evidence)
Mendeliome v1.1945 CLDN2 Zornitza Stark Gene: cldn2 has been classified as Red List (Low Evidence).
Mendeliome v1.1944 CLDN2 Zornitza Stark changed review comment from: Azoospermia and nephrolithiasis: single multigenerational family reported.; to: Azoospermia and nephrolithiasis: single multigenerational family reported.

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Mendeliome v1.1944 CLDN2 Zornitza Stark changed review comment from: Pancreatitis: Numerous publications linking common variants at this locus with susceptibility to pancreatitis. KO mice do not have a pancreatic phenotype. Likely polygenic susceptibility rather than Mendelian disorder.; to: Pancreatitis: Numerous publications linking common variants at this locus with susceptibility to pancreatitis. KO mice do not have a pancreatic phenotype; have calciuria. Likely polygenic susceptibility rather than Mendelian disorder.
Mendeliome v1.1944 CLDN2 Zornitza Stark changed review comment from: Azoospermia: single multigenerational family reported.; to: Azoospermia and nephrolithiasis: single multigenerational family reported.
Mendeliome v1.1944 CLDN2 Zornitza Stark edited their review of gene: CLDN2: Changed rating: RED
Mendeliome v0.6881 CLDN2 Zornitza Stark Phenotypes for gene: CLDN2 were changed from Susceptibility to pancreatitis to Susceptibility to pancreatitis; Azoospermia, obstructive, with nephrolithiasis, MIM# 301060
Mendeliome v0.6880 CLDN2 Zornitza Stark Publications for gene: CLDN2 were set to 29884332; 31163246
Mendeliome v0.6879 CLDN2 Zornitza Stark Mode of inheritance for gene: CLDN2 was changed from Other to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Mendeliome v0.6878 CLDN2 Zornitza Stark changed review comment from: Numerous publications linking common variants at this locus with susceptibility to pancreatitis. KO mice do not have a pancreatic phenotype. Likely polygenic susceptibility rather than Mendelian disorder.; to: Pancreatitis: Numerous publications linking common variants at this locus with susceptibility to pancreatitis. KO mice do not have a pancreatic phenotype. Likely polygenic susceptibility rather than Mendelian disorder.
Mendeliome v0.6878 CLDN2 Zornitza Stark edited their review of gene: CLDN2: Added comment: Azoospermia: single multigenerational family reported.; Changed publications: 29884332, 31163246, 31320686; Changed phenotypes: Susceptibility to pancreatitis, Azoospermia, obstructive, with nephrolithiasis, MIM# 301060; Changed mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Mendeliome v0.3529 CLDN2 Zornitza Stark Marked gene: CLDN2 as ready
Mendeliome v0.3529 CLDN2 Zornitza Stark Gene: cldn2 has been classified as Amber List (Moderate Evidence).
Mendeliome v0.3529 CLDN2 Zornitza Stark Phenotypes for gene: CLDN2 were changed from to Susceptibility to pancreatitis
Mendeliome v0.3528 CLDN2 Zornitza Stark Publications for gene: CLDN2 were set to
Mendeliome v0.3527 CLDN2 Zornitza Stark Mode of inheritance for gene: CLDN2 was changed from Unknown to Other
Mendeliome v0.3526 CLDN2 Zornitza Stark Classified gene: CLDN2 as Amber List (moderate evidence)
Mendeliome v0.3526 CLDN2 Zornitza Stark Gene: cldn2 has been classified as Amber List (Moderate Evidence).
Mendeliome v0.3525 CLDN2 Zornitza Stark reviewed gene: CLDN2: Rating: AMBER; Mode of pathogenicity: None; Publications: 29884332, 31163246; Phenotypes: Susceptibility to pancreatitis; Mode of inheritance: Other
Mendeliome v0.0 CLDN2 Zornitza Stark gene: CLDN2 was added
gene: CLDN2 was added to Mendeliome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services
Mode of inheritance for gene: CLDN2 was set to Unknown